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Showing 13 to 24 of 1130 entries
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Enantioselective incorporation of dicarboxylate guests by octacalcium phosphate.

Chemical communications (Cambridge, England)

Yokoi T, Machida S, Sugahara Y, Hashimoto M, Kitaoka S.
PMID: 28573292
Chem Commun (Camb). 2017 Jun 13;53(48):6524-6527. doi: 10.1039/c7cc01169e.

Enantioselectivity by octacalcium phosphate (OCP) is revealed through the incorporation of (S)-(-)-methylsuccinic acid (MeSuc) into its crystal lattice, with hardly any (R)-(+)-MeSuc incorporated. This phenomenon clearly indicates that OCP recognizes the steric structures of guest molecules, extending chiral recognition...

Comparison of incretin immunoassays with or without plasma extraction: Incretin secretion in Japanese patients with type 2 diabetes.

Journal of diabetes investigation

Yabe D, Watanabe K, Sugawara K, Kuwata H, Kitamoto Y, Sugizaki K, Fujiwara S, Hishizawa M, Hyo T, Kuwabara K, Yokota K, Iwasaki M, Kitatani N, Kurose T, Inagaki N, Seino Y.
PMID: 24843548
J Diabetes Investig. 2012 Feb 20;3(1):70-9. doi: 10.1111/j.2040-1124.2011.00141.x.

UNLABELLED: Aims/Introduction:  The effectiveness of incretin-based therapies in Asian type 2 diabetes requires investigation of the secretion and metabolism of glucose-dependent insulinotropic polypepide (GIP) and glucagon-like peptide 1 (GLP-1). Plasma extractions have been suggested to reduce variability in intact...

Polyunsaturated fatty acids in serum and homocysteine concentrations in Japanese men and women: a cross-sectional study.

Nutrition & metabolism

Kume A, Kurotani K, Sato M, Ejima Y, Pham NM, Nanri A, Kuwahara K, Mizoue T.
PMID: 23758810
Nutr Metab (Lond). 2013 Jun 10;10(1):41. doi: 10.1186/1743-7075-10-41.

BACKGROUND: Supplementation studies have suggested a role of n-3 polyunsaturated fatty acids (PUFAs) in homocysteine metabolism, but the evidence is limited and inconsistent among studies that measured blood levels of n-3 and n-6 PUFAs. We examined the association between...

Factors Contributing to Erythropoietin Hyporesponsiveness in Patients on Long-Term Continuous Ambulatory Peritoneal Dialysis: A Cross-Sectional Study.

Nephron extra

Hara T, Mukai H, Nakashima T, Sagara R, Furusho M, Miura S, Toyonaga J, Sugawara K, Takeda K.
PMID: 26648974
Nephron Extra. 2015 Oct 28;5(3):79-86. doi: 10.1159/000441154. eCollection 2015.

BACKGROUND: Factors contributing to erythropoietin (EPO) hyporesponsiveness in patients on long-term continuous ambulatory peritoneal dialysis are not well understood. Therefore, we investigated the factors contributing to EPO hyporesponsiveness using the EPO resistance index (ERI).METHODS: A total of 14 patients...

Draft Genome Sequence of Acinetobacter calcoaceticus Strain P23, a Plant Growth-Promoting Bacterium of Duckweed.

Genome announcements

Sugawara M, Hosoyama A, Yamazoe A, Morikawa M.
PMID: 25720680
Genome Announc. 2015 Feb 26;3(1). doi: 10.1128/genomeA.00026-15.

Acinetobacter calcoaceticus strain P23 is a plant growth-promoting bacterium, which was isolated from the surface of duckweed. We report here the draft genome sequence of strain P23. The genome data will serve as a valuable reference for understanding the...

Diallyl sulfides: Selective inhibitors of family X DNA polymerases from garlic (Allium sativum L.).

Food chemistry

Nishida M, Hada T, Kuramochi K, Yoshida H, Yonezawa Y, Kuriyama I, Sugawara F, Yoshida H, Mizushina Y.
PMID: 26059133
Food Chem. 2008 May 15;108(2):551-60. doi: 10.1016/j.foodchem.2007.11.007. Epub 2007 Nov 13.

Diallyl sulfides, organosulfur compounds isolated from garlic (Allium sativum L.), selectively inhibit the activities of mammalian family X DNA polymerases (pols), such as pol β, pol λ and terminal deoxynucleotidyl transferase (TdT), in vitro. The purified fraction (i.e., Sample-A)...

Mechanisms of the immunosuppressive effects of mouse adipose tissue-derived mesenchymal stromal cells on mouse alloreactively stimulated spleen cells.

Experimental and therapeutic medicine

Nagaya R, Mizuno-Kamiya M, Takayama E, Kawaki H, Onoe I, Tanabe T, Nagahara K, Kondoh N.
PMID: 24348757
Exp Ther Med. 2014 Jan;7(1):17-22. doi: 10.3892/etm.2013.1382. Epub 2013 Nov 06.

The mechanisms of immunomodulation by mesenchymal stromal cells remain poorly understood. In this study, the effects of mouse adipose tissue-derived mesenchymal stromal cells (ASCs) on mouse spleen cells alloreactively stimulated by anti-CD3 and anti-CD28 antibody-coated (anti-CD3/CD28) beads were observed....

An Attempt at Captive Breeding of the Endangered Newt Echinotriton andersoni, from the Central Ryukyus in Japan.

Animals : an open access journal from MDPI

Igawa T, Sugawara H, Tado M, Nishitani T, Kurabayashi A, Islam MM, Oumi S, Katsuren S, Fujii T, Sumida M.
PMID: 26479528
Animals (Basel). 2013 Jul 31;3(3):680-92. doi: 10.3390/ani3030680.

Anderson's crocodile newt (Echinotriton andersoni) is distributed in the Central Ryukyu Islands of southern Japan, but environmental degradation and illegal collection over the last several decades have devastated the local populations. It has therefore been listed as a class...

Immunostimulatory activity of snake fruit peel extract on murine macrophage-like J774.1 cells.

Cytotechnology

Wijanarti S, Putra AB, Nishi K, Harmayani E, Sugahara T.
PMID: 26482737
Cytotechnology. 2016 Oct;68(5):1737-45. doi: 10.1007/s10616-015-9925-2. Epub 2015 Oct 19.

Snake fruit (Salacca edulis Reinw.) is a tropical fruit produced in Indonesia. Snake fruit peel is normally discarded as waste. In the present study, it was revealed that snake fruit peel has high bioactivities on stimulation of the immune...

Dietary phosphate exacerbates intestinal inflammation in experimental colitis.

Journal of clinical biochemistry and nutrition

Sugihara K, Masuda M, Nakao M, Abuduli M, Imi Y, Oda N, Okahisa T, Yamamoto H, Takeda E, Taketani Y.
PMID: 28955125
J Clin Biochem Nutr. 2017 Sep;61(2):91-99. doi: 10.3164/jcbn.16-117. Epub 2017 Jul 28.

The recent widespread consumption of Western diets and food additives worldwide is associated with excessive inorganic phosphate intake. However, researchers have known little about the impact of dietary phosphate intake on the development of inflammatory bowel disease to date....

Chronic hepatitis caused by hepatitis C virus showing a discrepancy between serogroup and genotype because of intergenotypic 2b/1b recombination: A pitfall in antiviral therapy with direct-acting antivirals.

Hepatology research : the official journal of the Japan Society of Hepatology

Kurata H, Uchida Y, Kouyama JI, Naiki K, Nakazawa M, Ando S, Nakao M, Motoya D, Sugawara K, Inao M, Imai Y, Nakayama N, Tomiya T, Mochida S.
PMID: 28872737
Hepatol Res. 2018 Feb;48(3):E372-E378. doi: 10.1111/hepr.12977. Epub 2017 Sep 25.

A 40-year-old male patient with virologic relapse after daclatasvir plus asunaprevir therapy for a serogroup 1 hepatitis C virus (HCV) infection visited our hospital for retreatment. Virologic examinations revealed that a genotype 2b HCV strain carrying both NS3-S122N /...

Next-Generation Sequencing-Based Molecular Diagnosis of Choroideremia.

Case reports in ophthalmology

Shimizu K, Oishi A, Oishi M, Ogino K, Morooka S, Sugahara M, Gotoh N, Yoshimura N.
PMID: 26327910
Case Rep Ophthalmol. 2015 Jul 25;6(2):246-50. doi: 10.1159/000437348. eCollection 2015.

We screened patients with choroideremia using next-generation sequencing (NGS) and identified a novel mutation and a known mutation in the CHM gene. One patient presented an atypical fundus appearance for choroideremia. Another patient presented macular hole retinal detachment in...

Showing 13 to 24 of 1130 entries