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Showing 25 to 36 of 142 entries
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Nanoparticle Albumin-bound Paclitaxel Plus Carboplatin Induction Followed by Nanoparticle Albumin-bound Paclitaxel Maintenance in Squamous Non-Small-cell Lung Cancer (ABOUND.sqm): A Phase III Randomized Clinical Trial.

Clinical lung cancer

Spigel DR, Jotte RM, Aix SP, Gressot L, Morgensztern D, McCleod M, Socinski MA, Daniel D, Juan-Vidal O, Mileham KF, West H, Page R, Reinmuth N, Knoble J, Chen T, Bhore R, Wolfsteiner M, Ong TJ, Gridelli C, Thomas M.
PMID: 33097414
Clin Lung Cancer. 2021 Jan;22(1):6-15.e4. doi: 10.1016/j.cllc.2020.09.007. Epub 2020 Sep 18.

BACKGROUND: We evaluated maintenance nanoparticle albumin-bound (nab) paclitaxel in the treatment of advanced squamous non-small-cell lung cancer.PATIENTS AND METHODS: Patients with treatment-naive squamous non-small-cell lung cancer received four 21-day cycles of nab-paclitaxel 100 mg/mRESULTS: Overall, 420 patients had received...

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Spigel DR, Jotte RM, Aix SP, et al. Nanoparticle Albumin-bound Paclitaxel Plus Carboplatin Induction Followed by Nanoparticle Albumin-bound Paclitaxel Maintenance in Squamous Non-Small-cell Lung Cancer (ABOUND.sqm): A Phase III Randomized Clinical Trial. Clin Lung Cancer. 2020;22(1):6-15.e4doi: 10.1016/j.cllc.2020.09.007.
Spigel, D. R., Jotte, R. M., Aix, S. P., Gressot, L., Morgensztern, D., McCleod, M., Socinski, M. A., Daniel, D., Juan-Vidal, O., Mileham, K. F., West, H., Page, R., Reinmuth, N., Knoble, J., Chen, T., Bhore, R., Wolfsteiner, M., Ong, T. J., Gridelli, C., Thomas, M. (2021). Nanoparticle Albumin-bound Paclitaxel Plus Carboplatin Induction Followed by Nanoparticle Albumin-bound Paclitaxel Maintenance in Squamous Non-Small-cell Lung Cancer (ABOUND.sqm): A Phase III Randomized Clinical Trial. Clinical lung cancer, 22(1), 6-15.e4. https://doi.org/10.1016/j.cllc.2020.09.007
Spigel, David R, et al. "Nanoparticle Albumin-bound Paclitaxel Plus Carboplatin Induction Followed by Nanoparticle Albumin-bound Paclitaxel Maintenance in Squamous Non-Small-cell Lung Cancer (ABOUND.sqm): A Phase III Randomized Clinical Trial." Clinical lung cancer vol. 22,1 (2021): 6-15.e4. doi: https://doi.org/10.1016/j.cllc.2020.09.007
Spigel DR, Jotte RM, Aix SP, Gressot L, Morgensztern D, McCleod M, Socinski MA, Daniel D, Juan-Vidal O, Mileham KF, West H, Page R, Reinmuth N, Knoble J, Chen T, Bhore R, Wolfsteiner M, Ong TJ, Gridelli C, Thomas M. Nanoparticle Albumin-bound Paclitaxel Plus Carboplatin Induction Followed by Nanoparticle Albumin-bound Paclitaxel Maintenance in Squamous Non-Small-cell Lung Cancer (ABOUND.sqm): A Phase III Randomized Clinical Trial. Clin Lung Cancer. 2021 Jan;22(1):6-15.e4. doi: 10.1016/j.cllc.2020.09.007. Epub 2020 Sep 18. PMID: 33097414.
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Is It the pH That Matters? Challenging the Pathophysiology of Acidemia in a Case of Severe Hypercapnia Secondary to Intraoperative CO.

Case reports in critical care

Merle E, Zaatari S, Spiegel R.
PMID: 33062341
Case Rep Crit Care. 2020 Sep 27;2020:1898759. doi: 10.1155/2020/1898759. eCollection 2020.

BACKGROUND: Acidemia has been long thought to lead to hemodynamic compromise. While some literature to date challenges this idea, there is no consensus on this topic.CASE SUMMARY: To our knowledge, this is the most severe case of hypercapnia and...

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Merle E, Zaatari S, Spiegel R. Is It the pH That Matters? Challenging the Pathophysiology of Acidemia in a Case of Severe Hypercapnia Secondary to Intraoperative CO. Case Rep Crit Care. 2020;2020:1898759doi: 10.1155/2020/1898759.
Merle, E., Zaatari, S., & Spiegel, R. (2020). Is It the pH That Matters? Challenging the Pathophysiology of Acidemia in a Case of Severe Hypercapnia Secondary to Intraoperative CO. Case reports in critical care, 20201898759. https://doi.org/10.1155/2020/1898759
Merle, Evan, et al. "Is It the pH That Matters? Challenging the Pathophysiology of Acidemia in a Case of Severe Hypercapnia Secondary to Intraoperative CO." Case reports in critical care vol. 2020 (2020): 1898759. doi: https://doi.org/10.1155/2020/1898759
Merle E, Zaatari S, Spiegel R. Is It the pH That Matters? Challenging the Pathophysiology of Acidemia in a Case of Severe Hypercapnia Secondary to Intraoperative CO. Case Rep Crit Care. 2020 Sep 27;2020:1898759. doi: 10.1155/2020/1898759. eCollection 2020. PMID: 33062341; PMCID: PMC7555461.
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Association of predation risk with a heterospecific vocalization by an anabantoid fish.

Journal of fish biology

Seigel AR, DeVriendt IG, Strand MC, Shastri A, Wisenden BD.
PMID: 34837222
J Fish Biol. 2021 Nov 27; doi: 10.1111/jfb.14965. Epub 2021 Nov 27.

Honey gouramis (Trichogaster chuna) received chemical alarm cues derived from conspecific epidermal tissue and, simultaneously, the vocalization produced by a heterospecific gourami species, the sparkling pygmy gourami (Trichopsis pumila). Control trials paired water with the vocalization. In trials that...

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Seigel AR, DeVriendt IG, Strand MC, et al. Association of predation risk with a heterospecific vocalization by an anabantoid fish. J Fish Biol. 2021;doi: 10.1111/jfb.14965.
Seigel, A. R., DeVriendt, I. G., Strand, M. C., Shastri, A., & Wisenden, B. D. (2021). Association of predation risk with a heterospecific vocalization by an anabantoid fish. Journal of fish biology, . https://doi.org/10.1111/jfb.14965
Seigel, Alex R, et al. "Association of predation risk with a heterospecific vocalization by an anabantoid fish." Journal of fish biology vol. (2021). doi: https://doi.org/10.1111/jfb.14965
Seigel AR, DeVriendt IG, Strand MC, Shastri A, Wisenden BD. Association of predation risk with a heterospecific vocalization by an anabantoid fish. J Fish Biol. 2021 Nov 27; doi: 10.1111/jfb.14965. Epub 2021 Nov 27. PMID: 34837222.
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Adavosertib with Chemotherapy in Patients with Primary Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer: An Open-Label, Four-Arm, Phase II Study.

Clinical cancer research : an official journal of the American Association for Cancer Research

Moore KN, Chambers SK, Hamilton EP, Chen LM, Oza AM, Ghamande SA, Konecny GE, Plaxe SC, Spitz DL, Geenen JJJ, Troso-Sandoval TA, Cragun JM, Rodrigo Imedio E, Kumar S, Mugundu GM, Lai Z, Chmielecki J, Jones SF, Spigel DR, Cadoo KA.
PMID: 34645648
Clin Cancer Res. 2022 Jan 01;28(1):36-44. doi: 10.1158/1078-0432.CCR-21-0158. Epub 2021 Oct 13.

PURPOSE: This study assessed the efficacy, safety, and pharmacokinetics of adavosertib in combination with four chemotherapy agents commonly used in patients with primary platinum-resistant ovarian cancer.PATIENTS AND METHODS: Women with histologically or cytologically confirmed epithelial ovarian, fallopian tube, or...

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Moore KN, Chambers SK, Hamilton EP, et al. Adavosertib with Chemotherapy in Patients with Primary Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer: An Open-Label, Four-Arm, Phase II Study. Clin Cancer Res. 2021;28(1):36-44doi: 10.1158/1078-0432.CCR-21-0158.
Moore, K. N., Chambers, S. K., Hamilton, E. P., Chen, L. M., Oza, A. M., Ghamande, S. A., Konecny, G. E., Plaxe, S. C., Spitz, D. L., Geenen, J. J. J., Troso-Sandoval, T. A., Cragun, J. M., Rodrigo Imedio, E., Kumar, S., Mugundu, G. M., Lai, Z., Chmielecki, J., Jones, S. F., Spigel, D. R., & Cadoo, K. A. (2022). Adavosertib with Chemotherapy in Patients with Primary Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer: An Open-Label, Four-Arm, Phase II Study. Clinical cancer research : an official journal of the American Association for Cancer Research, 28(1), 36-44. https://doi.org/10.1158/1078-0432.CCR-21-0158
Moore, Kathleen N, et al. "Adavosertib with Chemotherapy in Patients with Primary Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer: An Open-Label, Four-Arm, Phase II Study." Clinical cancer research : an official journal of the American Association for Cancer Research vol. 28,1 (2022): 36-44. doi: https://doi.org/10.1158/1078-0432.CCR-21-0158
Moore KN, Chambers SK, Hamilton EP, Chen LM, Oza AM, Ghamande SA, Konecny GE, Plaxe SC, Spitz DL, Geenen JJJ, Troso-Sandoval TA, Cragun JM, Rodrigo Imedio E, Kumar S, Mugundu GM, Lai Z, Chmielecki J, Jones SF, Spigel DR, Cadoo KA. Adavosertib with Chemotherapy in Patients with Primary Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer: An Open-Label, Four-Arm, Phase II Study. Clin Cancer Res. 2022 Jan 01;28(1):36-44. doi: 10.1158/1078-0432.CCR-21-0158. Epub 2021 Oct 13. PMID: 34645648.
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A Case of a Perinatal Woman on Methadone Maintenance Who Developed Postpartum Torsades de Pointes: Importance of Perinatal Changes in Drug Metabolism.

Journal of clinical psychopharmacology

Spiegel A, Spiegel DR, Byrd V, Hopkins K.
PMID: 34155161
J Clin Psychopharmacol. 2021 Jul-Aug 01;41(4):484-487. doi: 10.1097/JCP.0000000000001426.

No abstract available.

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Spiegel A, Spiegel DR, Byrd V, et al. A Case of a Perinatal Woman on Methadone Maintenance Who Developed Postpartum Torsades de Pointes: Importance of Perinatal Changes in Drug Metabolism. J Clin Psychopharmacol. 2021;41(4):484-487doi: 10.1097/JCP.0000000000001426.
Spiegel, A., Spiegel, D. R., Byrd, V., & Hopkins, K. (2021). A Case of a Perinatal Woman on Methadone Maintenance Who Developed Postpartum Torsades de Pointes: Importance of Perinatal Changes in Drug Metabolism. Journal of clinical psychopharmacology, 41(4), 484-487. https://doi.org/10.1097/JCP.0000000000001426
Spiegel, Ariana, et al. "A Case of a Perinatal Woman on Methadone Maintenance Who Developed Postpartum Torsades de Pointes: Importance of Perinatal Changes in Drug Metabolism." Journal of clinical psychopharmacology vol. 41,4 (2021): 484-487. doi: https://doi.org/10.1097/JCP.0000000000001426
Spiegel A, Spiegel DR, Byrd V, Hopkins K. A Case of a Perinatal Woman on Methadone Maintenance Who Developed Postpartum Torsades de Pointes: Importance of Perinatal Changes in Drug Metabolism. J Clin Psychopharmacol. 2021 Jul-Aug 01;41(4):484-487. doi: 10.1097/JCP.0000000000001426. PMID: 34155161.
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Survival Experience of 195 Patients with Hairy Cell Leukemia Treated in a Multi-Institutional Study with Interferon-Alfa 2B.

Leukemia & lymphoma

Golomb HM, Fefer A, Golde DW, Ozer H, Portlock C, Silber R, Rappeport J, Ratain MJ, Thompson J, Bonnem E, Spiegel R, Tensen L, Burke JS, Vardiman JW.
PMID: 27462938
Leuk Lymphoma. 1991;4(2):99-102. doi: 10.3109/10428199109068051.

One hundred ninety-five patients were entered into a multi-institutional study of interferon alfa 2b from 1983-1986; follow-up was completed through June 1989. A complete remission was documented in 7 patients, a partial remission in 152 patients, a minor response...

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Golomb HM, Fefer A, Golde DW, et al. Survival Experience of 195 Patients with Hairy Cell Leukemia Treated in a Multi-Institutional Study with Interferon-Alfa 2B. Leuk Lymphoma. 1991;4(2):99-102doi: 10.3109/10428199109068051.
Golomb, H. M., Fefer, A., Golde, D. W., Ozer, H., Portlock, C., Silber, R., Rappeport, J., Ratain, M. J., Thompson, J., Bonnem, E., Spiegel, R., Tensen, L., Burke, J. S., & Vardiman, J. W. (1991). Survival Experience of 195 Patients with Hairy Cell Leukemia Treated in a Multi-Institutional Study with Interferon-Alfa 2B. Leukemia & lymphoma, 4(2), 99-102. https://doi.org/10.3109/10428199109068051
Golomb, H M, et al. "Survival Experience of 195 Patients with Hairy Cell Leukemia Treated in a Multi-Institutional Study with Interferon-Alfa 2B." Leukemia & lymphoma vol. 4,2 (1991): 99-102. doi: https://doi.org/10.3109/10428199109068051
Golomb HM, Fefer A, Golde DW, Ozer H, Portlock C, Silber R, Rappeport J, Ratain MJ, Thompson J, Bonnem E, Spiegel R, Tensen L, Burke JS, Vardiman JW. Survival Experience of 195 Patients with Hairy Cell Leukemia Treated in a Multi-Institutional Study with Interferon-Alfa 2B. Leuk Lymphoma. 1991;4(2):99-102. doi: 10.3109/10428199109068051. PMID: 27462938.
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The Association of Malnutrition, illness duration, and pre-morbid weight status with anxiety and depression symptoms in adolescents and young adults with restrictive eating disorders: a cross-sectional study.

Journal of eating disorders

Lin JA, Jhe G, Vitagliano JA, Milliren CE, Spigel R, Woods ER, Forman SF, Richmond TK.
PMID: 34001260
J Eat Disord. 2021 May 17;9(1):60. doi: 10.1186/s40337-021-00415-7.

BACKGROUND: Restrictive eating disorders (EDs) are often comorbid with anxiety and depression symptoms, placing patients at risk for more severe disease, worse treatment outcomes, and higher rates of mortality. To identify risks for developing such co-morbidities, we assessed the...

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Lin JA, Jhe G, Vitagliano JA, et al. The Association of Malnutrition, illness duration, and pre-morbid weight status with anxiety and depression symptoms in adolescents and young adults with restrictive eating disorders: a cross-sectional study. J Eat Disord. 2021;9(1):60doi: 10.1186/s40337-021-00415-7.
Lin, J. A., Jhe, G., Vitagliano, J. A., Milliren, C. E., Spigel, R., Woods, E. R., Forman, S. F., & Richmond, T. K. (2021). The Association of Malnutrition, illness duration, and pre-morbid weight status with anxiety and depression symptoms in adolescents and young adults with restrictive eating disorders: a cross-sectional study. Journal of eating disorders, 9(1), 60. https://doi.org/10.1186/s40337-021-00415-7
Lin, Jessica A, et al. "The Association of Malnutrition, illness duration, and pre-morbid weight status with anxiety and depression symptoms in adolescents and young adults with restrictive eating disorders: a cross-sectional study." Journal of eating disorders vol. 9,1 (2021): 60. doi: https://doi.org/10.1186/s40337-021-00415-7
Lin JA, Jhe G, Vitagliano JA, Milliren CE, Spigel R, Woods ER, Forman SF, Richmond TK. The Association of Malnutrition, illness duration, and pre-morbid weight status with anxiety and depression symptoms in adolescents and young adults with restrictive eating disorders: a cross-sectional study. J Eat Disord. 2021 May 17;9(1):60. doi: 10.1186/s40337-021-00415-7. PMID: 34001260; PMCID: PMC8127488.
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A functional diagnosis of dysphagia using videoendoscopy.

Ear, nose, & throat journal

Spiegel JR, Selber JC, Creed J.
PMID: 9745179
Ear Nose Throat J. 1998 Aug;77(8):628-32.

No abstract available.

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Spiegel JR, Selber JC, Creed J. A functional diagnosis of dysphagia using videoendoscopy. Ear Nose Throat J. 1998;77(8):628-32
Spiegel, J. R., Selber, J. C., & Creed, J. (1998). A functional diagnosis of dysphagia using videoendoscopy. Ear, nose, & throat journal, 77(8), 628-32.
Spiegel, J R, et al. "A functional diagnosis of dysphagia using videoendoscopy." Ear, nose, & throat journal vol. 77,8 (1998): 628-32.
Spiegel JR, Selber JC, Creed J. A functional diagnosis of dysphagia using videoendoscopy. Ear Nose Throat J. 1998 Aug;77(8):628-32. PMID: 9745179.
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Rimegepant in the Treatment of Migraine Headache: The Importance of Comparator Treatments: November 2019 Annals of Emergency Medicine Journal Club.

Annals of emergency medicine

Ju C, Spiegel R, Radecki R, Swaminathan AK.
PMID: 31668246
Ann Emerg Med. 2019 Nov;74(5):721-723. doi: 10.1016/j.annemergmed.2019.09.014.

No abstract available.

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Ju C, Spiegel R, Radecki R, et al. Rimegepant in the Treatment of Migraine Headache: The Importance of Comparator Treatments: November 2019 Annals of Emergency Medicine Journal Club. Ann Emerg Med. 2019;74(5):721-723doi: 10.1016/j.annemergmed.2019.09.014.
Ju, C., Spiegel, R., Radecki, R., & Swaminathan, A. K. (2019). Rimegepant in the Treatment of Migraine Headache: The Importance of Comparator Treatments: November 2019 Annals of Emergency Medicine Journal Club. Annals of emergency medicine, 74(5), 721-723. https://doi.org/10.1016/j.annemergmed.2019.09.014
Ju, Christine, et al. "Rimegepant in the Treatment of Migraine Headache: The Importance of Comparator Treatments: November 2019 Annals of Emergency Medicine Journal Club." Annals of emergency medicine vol. 74,5 (2019): 721-723. doi: https://doi.org/10.1016/j.annemergmed.2019.09.014
Ju C, Spiegel R, Radecki R, Swaminathan AK. Rimegepant in the Treatment of Migraine Headache: The Importance of Comparator Treatments: November 2019 Annals of Emergency Medicine Journal Club. Ann Emerg Med. 2019 Nov;74(5):721-723. doi: 10.1016/j.annemergmed.2019.09.014. PMID: 31668246.
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In Reply.

Anesthesiology

Safavynia SA, Keating G, Speigel I, Fidler JA, Kreuzer M, Rye DB, Jenkins A, García PS.
PMID: 28098616
Anesthesiology. 2017 Feb;126(2):352-353. doi: 10.1097/ALN.0000000000001446.

No abstract available.

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Safavynia SA, Keating G, Speigel I, et al. In Reply. Anesthesiology. 2017;126(2):352-353doi: 10.1097/ALN.0000000000001446.
Safavynia, S. A., Keating, G., Speigel, I., Fidler, J. A., Kreuzer, M., Rye, D. B., Jenkins, A., & García, P. S. (2017). In Reply. Anesthesiology, 126(2), 352-353. https://doi.org/10.1097/ALN.0000000000001446
Safavynia, Seyed A, et al. "In Reply." Anesthesiology vol. 126,2 (2017): 352-353. doi: https://doi.org/10.1097/ALN.0000000000001446
Safavynia SA, Keating G, Speigel I, Fidler JA, Kreuzer M, Rye DB, Jenkins A, García PS. In Reply. Anesthesiology. 2017 Feb;126(2):352-353. doi: 10.1097/ALN.0000000000001446. PMID: 28098616; PMCID: PMC5340312.
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A Case of Psychosis in a Patient with Secondary Adrenal Insufficiency: A Possible Etiological Role of a Hypocortisolemic-induced Increase in Proinflammatory Cytokines.

Innovations in clinical neuroscience

Spiegel DR, Nelson AB, Lieb DC, Pattison AM, Smith J, Zigrossi P, Godbout E.
PMID: 29344425
Innov Clin Neurosci. 2017 Oct 01;14(9):4-10. eCollection 2017.

Adrenal insufficiency is divided into three types based on the etiology of its development. In primary adrenal insufficiency, pathology resides in end-organ failure at the level of the adrenal cortex, while in secondary and tertiary adrenal insufficiency, impairment rests...

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Spiegel DR, Nelson AB, Lieb DC, et al. A Case of Psychosis in a Patient with Secondary Adrenal Insufficiency: A Possible Etiological Role of a Hypocortisolemic-induced Increase in Proinflammatory Cytokines. Innov Clin Neurosci. 2017;14(9):4-10
Spiegel, D. R., Nelson, A. B., Lieb, D. C., Pattison, A. M., Smith, J., Zigrossi, P., & Godbout, E. (2017). A Case of Psychosis in a Patient with Secondary Adrenal Insufficiency: A Possible Etiological Role of a Hypocortisolemic-induced Increase in Proinflammatory Cytokines. Innovations in clinical neuroscience, 14(9), 4-10.
Spiegel, David R, et al. "A Case of Psychosis in a Patient with Secondary Adrenal Insufficiency: A Possible Etiological Role of a Hypocortisolemic-induced Increase in Proinflammatory Cytokines." Innovations in clinical neuroscience vol. 14,9 (2017): 4-10.
Spiegel DR, Nelson AB, Lieb DC, Pattison AM, Smith J, Zigrossi P, Godbout E. A Case of Psychosis in a Patient with Secondary Adrenal Insufficiency: A Possible Etiological Role of a Hypocortisolemic-induced Increase in Proinflammatory Cytokines. Innov Clin Neurosci. 2017 Oct 01;14(9):4-10. eCollection 2017. PMID: 29344425; PMCID: PMC5749956.
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Reply to J.J. Tao et al.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Hainsworth JD, Meric-Bernstam F, Swanton C, Hurwitz H, Spigel DR, Sweeney C, Burris H, Bose R, Yoo B, Stein A, Beattie M, Kurzrock R.
PMID: 29856693
J Clin Oncol. 2018 Aug 10;36(23):2451. doi: 10.1200/JCO.2018.78.6392. Epub 2018 Jun 01.

No abstract available.

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Hainsworth JD, Meric-Bernstam F, Swanton C, et al. Reply to J.J. Tao et al. J Clin Oncol. 2018;36(23):2451doi: 10.1200/JCO.2018.78.6392.
Hainsworth, J. D., Meric-Bernstam, F., Swanton, C., Hurwitz, H., Spigel, D. R., Sweeney, C., Burris, H., Bose, R., Yoo, B., Stein, A., Beattie, M., & Kurzrock, R. (2018). Reply to J.J. Tao et al. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 36(23), 2451. https://doi.org/10.1200/JCO.2018.78.6392
Hainsworth, John D, et al. "Reply to J.J. Tao et al." Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 36,23 (2018): 2451. doi: https://doi.org/10.1200/JCO.2018.78.6392
Hainsworth JD, Meric-Bernstam F, Swanton C, Hurwitz H, Spigel DR, Sweeney C, Burris H, Bose R, Yoo B, Stein A, Beattie M, Kurzrock R. Reply to J.J. Tao et al. J Clin Oncol. 2018 Aug 10;36(23):2451. doi: 10.1200/JCO.2018.78.6392. Epub 2018 Jun 01. PMID: 29856693.
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