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Showing 13 to 24 of 132 entries
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Expression of amphiregulin, cripto-1, and heregulin-alpha in human breast-cancer cells.

International journal of oncology

Normanno N, Qi C, Gullick W, Persico G, Yarden Y, Wen D, Plowman G, Kenney N, Johnson G, Kim N, Brandt R, Martinezlacaci I, Dickson R, Salomon D.
PMID: 21573645
Int J Oncol. 1993 Jun;2(6):903-11. doi: 10.3892/ijo.2.6.903.

Cripto-1 (CR-1), amphiregulin (AR), and heregulin alpha (HRGalpha) are three recently discovered epidermal growth factor (EGF)-related peptides. The expression of these proteins was determined in MCF-7, ZR-75-1, T-47D, SK-BR-3, MDA-MB-231, MDA-MB-468, and Hs-578T human breast cancer cell lines using...

MultiCASE Expert Systems and the REACH Initiative.

Toxicology mechanisms and methods

Saiakhov RD, Klopman G.
PMID: 20020912
Toxicol Mech Methods. 2008;18(2):159-75. doi: 10.1080/15376510701857460.

ABSTRACT This article is a review of the MultiCASE Inc. software and expert systems and their use to assess acute toxicity, mutagenicity, carcinogenicity, and other health effects. It is demonstrated that MultiCASE expert systems satisfy the guidelines of the...

Missense Mutations of the Pro65 Residue of PCGF2 Cause a Recognizable Syndrome Associated with Craniofacial, Neurological, Cardiovascular, and Skeletal Features.

American journal of human genetics

Turnpenny PD, Wright MJ, Sloman M, Caswell R, van Essen AJ, Gerkes E, Pfundt R, White SM, Shaul-Lotan N, Carpenter L, Schaefer GB, Fryer A, Innes AM, Forbes KP, Chung WK, McLaughlin H, Henderson LB, Roberts AE, Heath KE, Paumard-Hernández B, Gener B, Fawcett KA, Gjergja-Juraški R, Pilz DT, Fry AE.
PMID: 30343942
Am J Hum Genet. 2018 Nov 01;103(5):786-793. doi: 10.1016/j.ajhg.2018.09.012. Epub 2018 Oct 18.

PCGF2 encodes the polycomb group ring finger 2 protein, a transcriptional repressor involved in cell proliferation, differentiation, and embryogenesis. PCGF2 is a component of the polycomb repressive complex 1 (PRC1), a multiprotein complex which controls gene silencing through histone...

A Novel Drug, CC-122, Inhibits Tumor Growth in Hepatocellular Carcinoma through Downregulation of an Oncogenic TCF-4 Isoform.

Translational oncology

Tomimaru Y, Aihara A, Wands JR, Aloman C, Kim M.
PMID: 31352197
Transl Oncol. 2019 Oct;12(10):1345-1356. doi: 10.1016/j.tranon.2019.07.002. Epub 2019 Jul 25.

Immunomodulatory drugs such as lenalidomide (LEN) have shown significant anti-tumor activity against hematologic malignancies and they may have similar actions on solid tumors as well. We studied the effect of a new analog of the immunomodulatory drugs (CC-122) on...

Surgical management of moderate adolescent idiopathic scoliosis with a fusionless posterior dynamic deformity correction device: interim results with bridging 5-6 disc levels at 2 or more years of follow-up.

Journal of neurosurgery. Spine

Floman Y, El-Hawary R, Millgram MA, Lonner BS, Betz RR.
PMID: 31923888
J Neurosurg Spine. 2020 Jan 10;1-7. doi: 10.3171/2019.11.SPINE19827. Epub 2020 Jan 10.

OBJECTIVE: A posterior dynamic deformity correction (PDDC) system was used to correct adolescent idiopathic scoliosis (AIS) without fusion. The preliminary outcomes of bridging only 3-4 discs in patients with variable curve severity have previously been reported. This paper examines...

Direct observation of incommensurate magnetism in Hubbard chains.

Nature

Salomon G, Koepsell J, Vijayan J, Hilker TA, Nespolo J, Pollet L, Bloch I, Gross C.
PMID: 30542155
Nature. 2019 Jan;565(7737):56-60. doi: 10.1038/s41586-018-0778-7. Epub 2018 Dec 12.

The interplay between magnetism and doping is at the origin of exotic strongly correlated electronic phases and can lead to novel forms of magnetic ordering. One example is the emergence of incommensurate spin-density waves, which have wavevectors that do...

Managing evidence in food safety and nutrition.

EFSA journal. European Food Safety Authority

Cavalli E, Gilsenan M, Van Doren J, Grahek-Ogden D, Richardson J, Abbinante F, Cascio C, Devalier P, Brun N, Linkov I, Marchal K, Meek B, Pagliari C, Pasquetto I, Pirolli P, Sloman S, Tossounidis L, Waigmann E, Schünemann H, Verhagen H.
PMID: 32626441
EFSA J. 2019 Jul 08;17:e170704. doi: 10.2903/j.efsa.2019.e170704. eCollection 2019 Jul.

Evidence ('data') is at the heart of EFSA's 2020 Strategy and is addressed in three of its operational objectives: (1) adopt an open data approach, (2) improve data interoperability to facilitate data exchange, and (3) migrate towards structured scientific...

68Ga-Prostate-Specific Membrane Antigen Positron Emission Tomography-Computed Tomography-Based Primary Staging and Histological Correlation after Extended Pelvic Lymph Node Dissection in Intermediate-Risk Prostate Cancer.

Urologia internationalis

Kopp D, Kopp J, Bernhardt E, Manka L, Beck A, Gerullis H, Karakiewicz PI, Salomon G, Wiggermann P, Hammerer P, Schiffmann J.
PMID: 33965965
Urol Int. 2022;106(1):56-62. doi: 10.1159/000515651. Epub 2021 May 07.

OBJECTIVE: The objective of this study is to evaluate prostate-specific membrane antigen positron emission tomography-computed tomography (PSMA PET/CT)-based primary staging in exclusively D'Amico intermediate-risk prostate cancer (PCa) patients.PATIENTS AND METHODS: We relied on the Braunschweig institutional database and retrospectively...

Delayed Hematogenous Metastasis Versus Second Primary Squamous Cell Carcinoma of the Neck in a Patient With Previous Cancer of the Cervix.

The American surgeon

Coriell P, Engledow K, Roy S, Smith G, Nashed N, Slotman G.
PMID: 34818901
Am Surg. 2021 Nov 24;31348211060444. doi: 10.1177/00031348211060444. Epub 2021 Nov 24.

Squamous cell carcinoma (SCC) of the uterine cervix commonly spreads through direct infiltration and disseminates by lymphatic or hematogenous pathways. The most frequent locations for metastasis are lungs, liver, and bone. Other distant metastatic sites are rare, with only...

Evaluating Physician Burnout and the Need for Organizational Support.

Missouri medicine

Abid R, Salzman G.
PMID: 34149071
Mo Med. 2021 May-Jun;118(3):185-190.

No abstract available.

Microscopic evolution of doped Mott insulators from polaronic metal to Fermi liquid.

Science (New York, N.Y.)

Koepsell J, Bourgund D, Sompet P, Hirthe S, Bohrdt A, Wang Y, Grusdt F, Demler E, Salomon G, Gross C, Bloch I.
PMID: 34591626
Science. 2021 Oct;374(6563):82-86. doi: 10.1126/science.abe7165. Epub 2021 Sep 30.

[Figure: see text].

Varieties Of Evolved Forms Of Consciousness, Including Mathematical Consciousness.

Entropy (Basel, Switzerland)

Sloman A.
PMID: 33286386
Entropy (Basel). 2020 Jun 02;22(6). doi: 10.3390/e22060615.

I shall introduce a complex, apparently unique, cross-disciplinary approach to understanding consciousness, especially ancient forms of mathematical consciousness, based on joint work with Jackie Chappell (Birmingham Biosciences) on the Meta-Configured Genome (MCG) theory. All known forms of consciousness (apart...

Showing 13 to 24 of 132 entries