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Showing 25 to 36 of 37 entries
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Human semen quality in the new millennium: a prospective cross-sectional population-based study of 4867 men.

BMJ open

Jørgensen N, Joensen UN, Jensen TK, Jensen MB, Almstrup K, Olesen IA, Juul A, Andersson AM, Carlsen E, Petersen JH, Toppari J, Skakkebæk NE.
PMID: 22761286
BMJ Open. 2012 Jul 02;2(4). doi: 10.1136/bmjopen-2012-000990. Print 2012.

OBJECTIVES: Considerable interest and controversy over a possible decline in semen quality during the 20th century raised concern that semen quality could have reached a critically low level where it might affect human reproduction. The authors therefore initiated a...

Maternal exposure to UV filters: associations with maternal thyroid hormones, IGF-I/IGFBP3 and birth outcomes.

Endocrine connections

Krause M, Frederiksen H, Sundberg K, Jørgensen FS, Jensen LN, Nørgaard P, Jørgensen C, Ertberg P, Petersen JH, Feldt-Rasmussen U, Juul A, Drzewiecki KT, Skakkebaek NE, Andersson AM.
PMID: 29362228
Endocr Connect. 2018 Feb;7(2):334-346. doi: 10.1530/EC-17-0375. Epub 2018 Jan 23.

BACKGROUND: Several chemical UV filters/absorbers ('UV filters' hereafter) have endocrine-disrupting properties OBJECTIVES: To examine maternal exposure to UV filters, associations with maternal thyroid hormone, with growth factor concentrations as well as to birth outcomes.METHODS: Prospective study of 183 pregnant...

Clinical aspects of testicular carcinoma-in-situ.

International journal of andrology

Skakkebaek NE, Berthelsen JG, Visfeldt J.
PMID: 29112258
Int J Androl. 1981 Mar;4:153-160. doi: 10.1111/j.1365-2605.1981.tb00668.x.

Carcinoma-in-situ germ cells were demonstrated in testicular biopsies from 9 of 826 patients (1.1%) from a selected group of Danish infertile men. A similar observation was noted in testicular biopsies from 9 Swiss patients (representing 0.55% of the total...

Environmental factors in declining human fertility.

Nature reviews. Endocrinology

Skakkebæk NE, Lindahl-Jacobsen R, Levine H, Andersson AM, Jørgensen N, Main KM, Lidegaard Ø, Priskorn L, Holmboe SA, Bräuner EV, Almstrup K, Franca LR, Znaor A, Kortenkamp A, Hart RJ, Juul A.
PMID: 34912078
Nat Rev Endocrinol. 2021 Dec 15; doi: 10.1038/s41574-021-00598-8. Epub 2021 Dec 15.

A severe decline in child births has occurred over the past half century, which will lead to considerable population declines, particularly in industrialized regions. A crucial question is whether this decline can be explained by economic and behavioural factors...

Endocrine Disrupting Chemicals and Risk of Testicular Cancer: A Systematic Review and Meta-analysis.

The Journal of clinical endocrinology and metabolism

Bräuner EV, Lim YH, Koch T, Uldbjerg CS, Gregersen LS, Pedersen MK, Frederiksen H, Petersen JH, Coull BA, Andersson AM, Hickey M, Skakkebæk NE, Hauser R, Juul A.
PMID: 34270734
J Clin Endocrinol Metab. 2021 Nov 19;106(12):e4834-e4860. doi: 10.1210/clinem/dgab523.

The incidence of many hormone-dependent diseases, including testicular cancer, has sharply increased in all high-income countries during the 20th century. This is not fully explained by established risk factors. Concurrent, increasing exposure to antiandrogenic environmental endocrine disrupting chemicals (EDCs)...

Semen quality of 1559 young men from four cities in Japan: a cross-sectional population-based study.

BMJ open

Iwamoto T, Nozawa S, Mieno MN, Yamakawa K, Baba K, Yoshiike M, Namiki M, Koh E, Kanaya J, Okuyama A, Matsumiya K, Tsujimura A, Kanetake H, Eguchi J, Skakkebaek NE, Vierula M, Toppari J, Jørgensen N.
PMID: 23633418
BMJ Open. 2013 Apr 29;3(4). doi: 10.1136/bmjopen-2012-002222. Print 2013.

OBJECTIVES: To provide information of semen quality among normal young Japanese men and indicate the frequency of reduced semen quality.DESIGN: Cross-sectional, coordinated studies of Japanese young men included from university areas. The men had to be 18-24 years, and...

Distribution of carcinoma-in-situ in testes from infertile men.

International journal of andrology

Berthelsen JG, Skakkebaek NE.
PMID: 29112256
Int J Androl. 1981 Mar;4:172-183. doi: 10.1111/j.1365-2605.1981.tb00672.x.

Quantitative histologial studies on 4 testes removed because of carcinoma-in-situ (CIS) were performed in order to determine the distribution of CIS within the testis and to estimate the likelihood of diagnosing testicular CIS by biopsy. The CIS changes were...

Foreword.

International journal of andrology

Skakkebœk NE, Grigor KM, Berthelsen JG, Visfeldt J.
PMID: 29112293
Int J Androl. 1981 Mar;4:9. doi: 10.1111/j.1365-2605.1981.tb00643.x.

No abstract available.

Sperm retrieval in adolescent males with Klinefelter syndrome: medical and ethical issues.

Translational pediatrics

Rogol AD, Skakkebaek NE.
PMID: 27186531
Transl Pediatr. 2016 Apr;5(2):104-6. doi: 10.21037/tp.2016.04.05.

No abstract available.

EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner.

Endocrine connections

Rehfeld A, Egeberg DL, Almstrup K, Petersen JH, Dissing S, Skakkebæk NE.
PMID: 28874401
Endocr Connect. 2018 Jan;7(1):16-25. doi: 10.1530/EC-17-0156. Epub 2017 Sep 05.

Human sperm cell function must be precisely regulated to achieve natural fertilization. Progesterone released by the cumulus cells surrounding the egg induces a Ca

Pubarche and Gonadarche Onset and Progression Are Differently Associated With Birth Weight and Infancy Growth Patterns.

Journal of the Endocrine Society

Wohlfahrt-Veje C, Tinggaard J, Juul A, Toppari J, Skakkebæk NE, Main KM.
PMID: 34250379
J Endocr Soc. 2021 Jun 10;5(8):bvab108. doi: 10.1210/jendso/bvab108. eCollection 2021 Aug 01.

CONTEXT: Controversy exists regarding associations between early-life growth patterns and timing of puberty.OBJECTIVE: This work aims to investigate associations between birth anthropometry, early growth patterns, and onset/progression of pubertal milestones in boys and girls.METHODS: Among children examined at birth...

Pubarche and Gonadarche Onset and Progression Are Differently Associated With Birth Weight and Infancy Growth Patterns.

Journal of the Endocrine Society

Wohlfahrt-Veje C, Tinggaard J, Juul A, Toppari J, Skakkebæk NE, Main KM.
PMID: 34250379
J Endocr Soc. 2021 Jun 10;5(8):bvab108. doi: 10.1210/jendso/bvab108. eCollection 2021 Aug 01.

CONTEXT: Controversy exists regarding associations between early-life growth patterns and timing of puberty.OBJECTIVE: This work aims to investigate associations between birth anthropometry, early growth patterns, and onset/progression of pubertal milestones in boys and girls.METHODS: Among children examined at birth...

Showing 25 to 36 of 37 entries