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Showing 9985 to 9996 of 27590 entries
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Assessement of Blood Lead and Cadmium Levels in Occupationally Exposed Workers of Jodhpur, Rajasthan.

Indian journal of clinical biochemistry : IJCB

Goyal T, Mitra P, Singh P, Sharma S, Sharma P.
PMID: 33505134
Indian J Clin Biochem. 2021 Jan;36(1):100-107. doi: 10.1007/s12291-020-00878-6. Epub 2020 Mar 14.

In spite of the established knowledge regarding their toxicities, occupational exposure to heavy metals like lead and cadmium still continues because of their wide distribution in environment. Due to lack of awareness, most of the workers usually eat, smoke,...

Patient experiences and perceptions of chronic disease care during the COVID-19 pandemic in India: a qualitative study.

BMJ open

Singh K, Kaushik A, Johnson L, Jaganathan S, Jarhyan P, Deepa M, Kong S, Venkateshmurthy NS, Kondal D, Mohan S, Anjana RM, Ali MK, Tandon N, Narayan KMV, Mohan V, Eggleston K, Prabhakaran D.
PMID: 34145019
BMJ Open. 2021 Jun 18;11(6):e048926. doi: 10.1136/bmjopen-2021-048926.

OBJECTIVE: People with chronic conditions are known to be vulnerable to the COVID-19 pandemic. This study aims to describe patients' lived experiences, challenges faced by people with chronic conditions, their coping strategies, and the social and economic impacts of...

Intensive care outcome of left main stem disease surgery: A single center three years' experience.

World journal of critical care medicine

Omar AS, Hanoura S, Shouman Y, Sivadasan PC, Sudarsanan S, Osman H, Pattath AR, Singh R, AlKhulaifi A.
PMID: 33505869
World J Crit Care Med. 2021 Jan 09;10(1):12-21. doi: 10.5492/wjccm.v10.i1.12. eCollection 2021 Jan 09.

BACKGROUND: Left main coronary artery (LMCA) supplies more than 80% of the left ventricle, and significant disease of this artery carries a high mortality unless intervened surgically. However, the influence of coronary artery bypass grafting (CABG) surgery on patients...

Prevalence and predictors of low bone mineral density in treatment-naive HIV-infected patients and its correlation with CD4 cell counts.

Tzu chi medical journal

Gupta PK, Singh S, Mahto SK, Sheoran A, Garga UC, Lal AK, Jain P, Mathews SE.
PMID: 33505878
Tzu Chi Med J. 2020 Apr 10;33(1):49-54. doi: 10.4103/tcmj.tcmj_177_19. eCollection 2021.

OBJECTIVE: HIV virtually affects every organ system of the body. The skeletal system is no exception, and antiretroviral therapy (ART) has been implicated in bone diseases. However, not many studies have been done to evaluate bone disease in treatment...

Clinical Profile and Risk Factors for Severe Disease in 402 Children Hospitalized with SARS-CoV-2 from India: Collaborative Indian Pediatric COVID Study Group.

Journal of tropical pediatrics

Jat KR, Sankar J, Das RR, Ratageri VH, Choudhary B, Bhat JI, Mishra B, Bhatnagar S, Behera B, Charoo BA, Goyal JP, Gupta AK, Gulla KM, Gera R, Illalu S, Kabra SK, Khera D, Kumar B, Lodha R, Mohan A, Mohanty PK, Satapathy AK, Singh K, Singh A, Sharma SV, Tiwari P, Trikha A, Wari PK.
PMID: 34152424
J Trop Pediatr. 2021 Jul 02;67(3). doi: 10.1093/tropej/fmab048.

INTRODUCTION: There is a lack of large multicentric studies in children with COVID-19 from developing countries. We aimed to describe the clinical profile and risk factors for severe disease in children hospitalized with COVID-19 from India.METHODS: In this multicentric...

FDA Approval Summary: Nivolumab with Ipilimumab and Chemotherapy for Metastatic Non-small Cell Lung Cancer, A Collaborative Project Orbis Review.

Clinical cancer research : an official journal of the American Association for Cancer Research

Vellanki PJ, Mulkey F, Jaigirdar AA, Rodriguez L, Wang Y, Xu Y, Zhao H, Liu J, Howe G, Wang J, Choo Q, Golding SJ, Mansell V, Korsah K, Spillman D, de Claro RA, Pazdur R, Beaver JA, Singh H.
PMID: 33632925
Clin Cancer Res. 2021 Jul 01;27(13):3522-3527. doi: 10.1158/1078-0432.CCR-20-4338. Epub 2021 Feb 25.

On May 26, 2020, the FDA approved nivolumab with ipilimumab and two cycles of platinum-doublet chemotherapy as first-line treatment for patients with metastatic or recurrent non-small cell lung cancer (NSCLC), with no

APOBEC3, TRIM5α, and BST2 polymorphisms in healthy individuals of various populations with special references to its impact on HIV transmission.

Microbial pathogenesis

Singh H, Jadhav S, Arif Khan A, Aggarwal SK, Choudhari R, Verma S, Aggarwal S, Gupta V, Singh A, Nain S, Maan HS.
PMID: 34863878
Microb Pathog. 2021 Dec 01;162:105326. doi: 10.1016/j.micpath.2021.105326. Epub 2021 Dec 01.

AIDS restriction genes (ARGs) like APOBEC3, TRIM5α, and BST2 can act as immunological detectors of the innate protective mechanism of the body. ARGs influence the course of viral pathogenesis and progression of the disease. The infection caused by different...

Hydrogen peroxide regulates antioxidant responses and redox related proteins in drought stressed wheat seedlings.

Physiology and molecular biology of plants : an international journal of functional plant biology

Bhardwaj RD, Singh N, Sharma A, Joshi R, Srivastava P.
PMID: 33679014
Physiol Mol Biol Plants. 2021 Jan;27(1):151-163. doi: 10.1007/s12298-021-00937-z. Epub 2021 Feb 01.

Hydrogen peroxide plays pivotal role as a potent regulator in signalling pathways when the plant is under stress. The current study appraised the potential of hydrogen peroxide through seed pre-treatment on the seedling growth and defense responses of three...

Correction: Loss of XIST in Breast Cancer Activates MSN-c-Met and Reprograms Microglia via Exosomal miRNA to Promote Brain Metastasis.

Cancer research

Xing F, Liu Y, Wu SY, Wu K, Sharma S, Mo YY, Feng J, Sanders S, Jin G, Singh R, Vidi PA, Tyagi A, Chan MD, Ruiz J, Debinski W, Pasche BC, Lo HW, Metheny-Barlow LJ, D'Agostino RB, Watabe K.
PMID: 34725134
Cancer Res. 2021 Nov 01;81(21):5582. doi: 10.1158/0008-5472.CAN-21-3056.

No abstract available.

Role of hyperpolarization-activated cyclic nucleotide-gated channels in aging bladder phenotype.

Life sciences

Singh N, Zabbarova I, Ikeda Y, Kanai A, Chermansky C, Yoshimura N, Tyagi P.
PMID: 34875252
Life Sci. 2022 Jan 15;289:120203. doi: 10.1016/j.lfs.2021.120203. Epub 2021 Dec 04.

OBJECTIVE: To assess the functional role of Hyperpolarization-activated cyclic nucleotide-gated gated channel (HCN) subtypes in the aging bladder phenotype characterized by diminished bladder volume sensation (BVS) with or without the detrusor instability (DI).METHODS: Expression of HCN subtypes was examined...

Overfeeding-induced weight gain elicits decreases in sex hormone-binding globulin in healthy males-Implications for body fat distribution.

Physiological reports

Singh P, Covassin N, Sert-Kuniyoshi FH, Marlatt KL, Romero-Corral A, Davison DE, Singh RJ, Jensen MD, Somers VK.
PMID: 34877821
Physiol Rep. 2021 Dec;9(23):e15127. doi: 10.14814/phy2.15127.

OBJECTIVE: Obesity and upper-body fat elevates cardiometabolic risk. However, mechanisms predisposing to upper-body fat accumulation are not completely understood. In males, low testosterone (T) frequently associates with obesity, and estrogen deficiency may contribute to upper-body adiposity. This study examines...

Zebrafish an experimental model of Huntington's disease: molecular aspects, therapeutic targets and current challenges.

Molecular biology reports

Kumar V, Singh C, Singh A.
PMID: 34665402
Mol Biol Rep. 2021 Dec;48(12):8181-8194. doi: 10.1007/s11033-021-06787-y. Epub 2021 Oct 19.

Huntington disease (HD) is a lethal autosomal dominant neurodegenerative disease whose exact causative mechanism is still unknown. It can transform from one generation to another generation. The CAG triplet expansion on polyglutamine (PolyQ) tract on Huntingtin protein primarily contributes...

Showing 9985 to 9996 of 27590 entries