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Showing 8725 to 8736 of 8736 entries
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The pharmacokinetic properties of artemether and lumefantrine in Malaysian patients with Plasmodium knowlesi malaria.

British journal of clinical pharmacology

Sugiarto SR, Singh B, Page-Sharp M, Davis WA, Salman S, Hii KC, Davis TME.
PMID: 34296469
Br J Clin Pharmacol. 2021 Jul 23; doi: 10.1111/bcp.15001. Epub 2021 Jul 23.

AIMS: The aim of this study was to assess the pharmacokinetic properties of artemether, lumefantrine and their active metabolites in Plasmodium knowlesi malaria.METHODS: Malaysian adults presenting with uncomplicated P. knowlesi infections received six doses of artemether (1.7 mg/kg) plus...

Safety and efficacy of azathioprine in immune thrombocytopenia.

American journal of blood research

Mishra K, Pramanik S, Sandal R, Jandial A, Sahu KK, Singh K, Khera S, Meshram A, Khurana H, Somasundaram V, Kumar R, Kapoor R, Verma T, Sharma S, Singh J, Das S, Chaterjee T, Sharma A, Nair V.
PMID: 34322284
Am J Blood Res. 2021 Jun 15;11(3):217-226. eCollection 2021.

BACKGROUND: Immune thrombocytopenia (ITP) is a benign hematological disorder characterized by low platelet counts in peripheral blood and spectrum of various bleeding manifestations. Azathioprine is one of the effective, readily available, and affordable immunosupressants available for ITP management in...

Molecular epidemiological studies on avian pathogenic Escherichia coli associated with septicemia in chickens in India.

Microbial pathogenesis

Narasinakuppe Krishnegowda D, Singh BR, Mariappan AK, Munuswamy P, Singh KP, Monalisa Sahoo, Saminathan M, Ramalingam R, Chellappa MM, Singh V, Dhama K, Reddy MR.
PMID: 34902538
Microb Pathog. 2021 Dec 10;105313. doi: 10.1016/j.micpath.2021.105313. Epub 2021 Dec 10.

Bacterial septicemia causes huge economic losses in the poultry industry and there is no systematic research available in India on the connection of various pathogens associated with septicemia. The present molecular epidemiological study was conducted to investigate the association...

Imaging of Pulmonary Superinfections and Co-Infections in COVID-19.

Current problems in diagnostic radiology

Naranje P, Bhalla AS, Jana M, Garg M, Nair AD, Singh SK, Banday I.
PMID: 34903396
Curr Probl Diagn Radiol. 2021 Nov 11; doi: 10.1067/j.cpradiol.2021.09.009. Epub 2021 Nov 11.

New challenges in imaging and management of COVID-19 pneumonia emerge as the pandemic continues across the globe. These arise not only due to the COVID-19 pneumonia but also related to various superinfections and co-infections. Limited use of bronchoscopic and...

Combining Ivacaftor and Intensive Antibiotics Achieves Limited Clearance of Cystic Fibrosis Infections.

mBio

Durfey SL, Pipavath S, Li A, Vo AT, Ratjen A, Carter S, Morgan SJ, Radey MC, Grogan B, Salipante SJ, Welsh MJ, Stoltz DA, Goss CH, McKone EF, Singh PK.
PMID: 34903059
mBio. 2021 Dec 14;e0314821. doi: 10.1128/mbio.03148-21. Epub 2021 Dec 14.

Drugs called CFTR modulators improve the physiologic defect underlying cystic fibrosis (CF) and alleviate many disease manifestations. However, studies to date indicate that chronic lung infections that are responsible for most disease-related mortality generally persist. Here, we investigated whether...

Organocatalytic Asymmetric Cascade Michael-acyl Transfer Reaction between 2-Fluoro-1,3-diketones and Unsaturated Thiazolones: Access to Fluorinated 4-Acyloxy Thiazoles.

Organic letters

Biswas RG, Ray SK, Unhale RA, Singh VK.
PMID: 34351776
Org Lett. 2021 Aug 20;23(16):6504-6509. doi: 10.1021/acs.orglett.1c02313. Epub 2021 Aug 05.

Quinine derived bifunctional urea catalyzed cascade Michael-acyl transfer reaction of 5-alkenyl thiazolones and monofluorinated β-diketones has been developed. The fluorine containing 4-acyloxy thiazoles were synthesized in high yields and good diastereo-and excellent enantioselectivities. Synthetic transformations, including synthesis of 4-hydroxy...

Social-ecological analysis of timely rice planting in Eastern India.

Agronomy for sustainable development

Urfels A, McDonald AJ, van Halsema G, Struik PC, Kumar P, Malik RK, Poonia SP, Balwinder-Singh, Singh DK, Singh M, Krupnik TJ.
PMID: 33680098
Agron Sustain Dev. 2021;41(2):14. doi: 10.1007/s13593-021-00668-1. Epub 2021 Feb 18.

Timely crop planting is a foundation for climate-resilient rice-wheat systems of the Eastern Gangetic Plains-a global food insecurity and poverty hotspot. We hypothesize that the capacity of individual farmers to plant on time varies considerably, shaped by multifaceted enabling...

Role of heterotrophic nitrifiers and aerobic denitrifiers in simultaneous nitrification and denitrification process: a nonconventional nitrogen removal pathway in wastewater treatment.

Letters in applied microbiology

Gupta RK, Poddar BJ, Nakhate SP, Chavan AR, Singh AK, Purohit HJ, Khardenavis AA.
PMID: 34402087
Lett Appl Microbiol. 2021 Aug 17; doi: 10.1111/lam.13553. Epub 2021 Aug 17.

Bacterial species capable of performing both nitrification and denitrification in a single vessel under similar conditions have gained significance in the wastewater treatment scenario considering their unique character of performing the above reactions under heterotrophic and aerobic conditions respectively....

How necessary are animal models for modern drug discovery?.

Expert opinion on drug discovery

Singh VK, Seed TM.
PMID: 34455867
Expert Opin Drug Discov. 2021 Dec;16(12):1391-1397. doi: 10.1080/17460441.2021.1972255. Epub 2021 Sep 03.

No abstract available.

Bioactive glasses and glass-ceramics for hyperthermia treatment of cancer: state-of-art, challenges, and future perspectives.

Materials today. Bio

Danewalia SS, Singh K.
PMID: 33778466
Mater Today Bio. 2021 Feb 24;10:100100. doi: 10.1016/j.mtbio.2021.100100. eCollection 2021 Mar.

Bioactive glasses and glass-ceramics are well-proven potential biomaterials for bone-tissue engineering applications because of their compositional flexibility. Many research groups have been focused to explore the utility of bioactive glass-ceramics beyond bone engineering to hyperthermia treatment of cancer. Hyperthermia...

Women in computer-related majors: A critical synthesis of research and theory from 1994 to 2005.

Singh K, Allen KR, Scheckler R, Darlington L.
UIID-AD: 298
2007;77:500-533. doi: 10.3102/0034654307309919.

In this article, the authors review, critique, and synthesize the emerging research literature from 1994 to 2005 on women's enrollment and persistence in computer-related majors. A thorough examination of 44 empirical studies in scholarly journals reveals that this literature...

A commentary on "Recruiting researchers in psychiatry: the influence of residency vs. early motivation".

Singh MK.
UIID-AD: 2886
2012;36:83-4. doi: 10.1176/appi.ap.12010002.

No abstract available.

Showing 8725 to 8736 of 8736 entries