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Showing 2005 to 2015 of 2015 entries
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Burn Center Organization and Cellular Therapy Integration: Managing Risks and Costs.

Journal of burn care & research : official publication of the American Burn Association

Chemali M, Laurent A, Scaletta C, Waselle L, Simon JP, Michetti M, Brunet JF, Flahaut M, Hirt-Burri N, Raffoul W, Applegate LA, de Buys Roessingh AS, Abdel-Sayed P.
PMID: 33970273
J Burn Care Res. 2021 Sep 30;42(5):911-924. doi: 10.1093/jbcr/irab080.

The complex management of severe burn victims requires an integrative collaboration of multidisciplinary specialists in order to ensure quality and excellence in healthcare. This multidisciplinary care has quickly led to the integration of cell therapies in clinical care of...

A Unified Approach to Polycyclic Alkaloids of the Ingenamine Estate: Total Syntheses of Keramaphidin B, Ingenamine, and Nominal Njaoamine I.

Journal of the American Chemical Society

Meng Z, Spohr SM, Tobegen S, Farès C, Fürstner A.
PMID: 34448391
J Am Chem Soc. 2021 Sep 08;143(35):14402-14414. doi: 10.1021/jacs.1c07955. Epub 2021 Aug 27.

Many polycyclic marine alkaloids are thought to derive from partly reduced macrocyclic alkylpyridine derivatives via a transannular Diels-Alder reaction that forms their common etheno-bridged diaza-decaline core ("Baldwin-Whitehead hypothesis"). Rather than trying to emulate this biosynthesis pathway, a route to...

Retrospective Evaluation of Progenitor Biological Bandage Use: A Complementary and Safe Therapeutic Management Option for Prevention of Hypertrophic Scarring in Pediatric Burn Care.

Pharmaceuticals (Basel, Switzerland)

Al-Dourobi K, Laurent A, Deghayli L, Flahaut M, Abdel-Sayed P, Scaletta C, Michetti M, Waselle L, Simon JP, Ezzi OE, Raffoul W, Applegate LA, Hirt-Burri N, Roessingh ASB.
PMID: 33671009
Pharmaceuticals (Basel). 2021 Feb 28;14(3). doi: 10.3390/ph14030201.

Progenitor Biological Bandages (PBB) have been continuously applied clinically in the Lausanne Burn Center for over two decades. Vast translational experience and hindsight have been gathered, specifically for cutaneous healing promotion of donor-site grafts and second-degree pediatric burns. PBBs...

Tumor mutation burden testing: a survey of the International Quality Network for Pathology (IQN Path).

Virchows Archiv : an international journal of pathology

Fenizia F, Wolstenholme N, Fairley JA, Rouleau E, Cheetham MH, Horan MP, Torlakovic E, Besse B, Al Dieri R, Tiniakos DG, Deans ZC, Patton SJ, Normanno N.
PMID: 33856555
Virchows Arch. 2021 Dec;479(6):1067-1072. doi: 10.1007/s00428-021-03093-7. Epub 2021 Apr 15.

While tumour mutation burden (TMB) is emerging as a possible biomarker for immune-checkpoint inhibitors (ICI), methods for testing have not been standardised as yet. In April 2019, the International Quality Network for Pathology (IQN Path) launched a survey to...

Effects of exposure to single and multiple parabens on asthma development in an experimental mouse model and a prospective cohort study.

The Science of the total environment

Junge KM, Buchenauer L, Strunz S, Seiwert B, Thürmann L, Rolle-Kampczyk UE, Röder S, Borte M, Kiess W, von Bergen M, Simon JC, Zenclussen AC, Schöneberg T, Stangl GI, Herberth G, Lehmann I, Reemtsma T, Polte T.
PMID: 34973317
Sci Total Environ. 2021 Dec 30;814:152676. doi: 10.1016/j.scitotenv.2021.152676. Epub 2021 Dec 30.

Parabens are widely used preservatives present in consumer products like cosmetics and food. Although several epidemiological studies suggest that early-life exposure to parabens might alter the immune response and allergy risk in childhood, the evidence with respect to asthma...

Validation of the Use of Dried Blood Samples for the Detection of .

Pathogens (Basel, Switzerland)

Simon JA, Aubert D, Geers R, Villena I, Poulle ML.
PMID: 34358014
Pathogens. 2021 Jul 08;10(7). doi: 10.3390/pathogens10070864.

If validated beforehand, the analysis of dried blood on blotting paper (BP samples) is very useful for monitoring free-ranging animals. We aimed to validate this method for the detection of antibodies against

Ultrasonic Atomization: A Mechanism of Tissue Fractionation.

Proceedings of meetings on acoustics. Acoustical Society of America

Simon JC, Sapozhnikov OA, Khokhlova VA, Wang YN, Crum LA, Bailey MR.
PMID: 34322192
Proc Meet Acoust. 2013 May;133(5). doi: 10.1121/1.4805524. Epub 2013 May 06.

High intensity focused ultrasound (HIFU) can be used to atomize liquid by creating a fountain on the surface exposed to air. The mechanism of atomization can be most accurately described by the cavitation-wave hypothesis wherein a combination of capillary...

[Acute intoxications in the intensive care unit: A 10-year analysis].

Medizinische Klinik, Intensivmedizin und Notfallmedizin

Siedler S, Trageser HB, Grensemann J, Hilgarth H, Simon M, Kluge S.
PMID: 34302193
Med Klin Intensivmed Notfmed. 2021 Jul 23; doi: 10.1007/s00063-021-00839-8. Epub 2021 Jul 23.

BACKGROUND: Acute intoxications play a special role in preclinical emergency medicine, in the emergency department, and in intensive care. This study characterizes cases of acute intoxications from an intensive care perspective.OBJECTIVES: All cases of acute intoxications admitted to the...

Oxidation of Protein Kinase A Regulatory Subunit PKARIα Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release.

Circulation

Simon JN, Vrellaku B, Monterisi S, Chu SM, Rawlings N, Lomas O, Marchal GA, Waithe D, Syeda F, Gajendragadkar PR, Jayaram R, Sayeed R, Channon KM, Fabritz L, Swietach P, Zaccolo M, Eaton P, Casadei B.
PMID: 33185461
Circulation. 2021 Feb 02;143(5):449-465. doi: 10.1161/CIRCULATIONAHA.120.046761. Epub 2020 Nov 13.

BACKGROUND: Kinase oxidation is a critical signaling mechanism through which changes in the intracellular redox state alter cardiac function. In the myocardium, PKARIα (type-1 protein kinase A) can be reversibly oxidized, forming interprotein disulfide bonds in the holoenzyme complex....

Access to Highly Stereodefined 1,4-.

Journal of the American Chemical Society

Fiorito D, Simon M, Thomas CM, Mazet C.
PMID: 34379408
J Am Chem Soc. 2021 Aug 25;143(33):13401-13407. doi: 10.1021/jacs.1c06553. Epub 2021 Aug 11.

A [Ni/Mg]-catalyzed orthogonal tandem polymerization has been developed starting from enol phosphates. Initial investigations conducted on branched 1,3-dienes as monomers enabled identification of a Mg-initiated polymerization process leading to 1,4-

Mentoring the Mentors of Underrepresented Racial/Ethnic Minorities Who are Conducting HIV Research: Beyond Cultural Competency.

Duran B, Walters KL, Simoni JM, Evans-Campbell TT, Udell W, Johnson-Jennings M, Pearson CR, MacDonald MM.
UIID-AD: 3780
2016;288-293. doi: 10.1007/s10461-016-1491-x.

The majority of literature on mentoring focuses on mentee training needs, with significantly less guidance for the mentors. Moreover, many mentoring the mentor models assume generic (i.e. White) mentees with little attention to the concerns of underrepresented racial/ethnic minorities...

Showing 2005 to 2015 of 2015 entries