Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 25 to 36 of 262 entries
Sorted by: Best Match Show Resources per page
Osimertinib as first-line therapy in advanced NSCLC: a profile of its use.

Drugs & therapy perspectives : for rational drug selection and use

Scott LJ.
PMID: 30631243
Drugs Ther Perspect. 2018;34(8):351-357. doi: 10.1007/s40267-018-0536-9. Epub 2018 Jul 06.

Osimertinib (Tagrisso

Serum Vascular Endothelial Growth Factor Levels in the IVAN Trial; Relationships with Drug, Dosing, and Systemic Serious Adverse Events.

Ophthalmology. Retina

Rogers CA, Scott LJ, Reeves BC, Downes S, Lotery AJ, Dick AD, Chakravarthy U.
PMID: 30555977
Ophthalmol Retina. 2018 Feb;2(2):118-127. doi: 10.1016/j.oret.2017.05.015.

PURPOSE: To describe serum vascular endothelial growth factor (sVEGF) in patients with neovascular age-related macular degeneration (nAMD) receiving anti-VEGF agents and associations between sVEGF and systemic serious adverse events (SSAEs).DESIGN: Exploratory analyses of a randomized controlled trial that enrolled...

A bacterial index to estimate lake trophic level: National scale validation.

The Science of the total environment

Pearman JK, Wood SA, Vandergoes MJ, Atalah J, Waters S, Adamson J, Thomson-Laing G, Thompson L, Howarth JD, Hamilton DP, Pochon X, Biessy L, Brasell KA, Dahl J, Ellison R, Fitzsimons SJ, Gard H, Gerrard T, Gregersen R, Holloway M, Li X, Kelly DJ, Martin R, McFarlane K, McKay NP, Moody A, Moy CM, Naeher S, Newnham R, Parai R, Picard M, Puddick J, Rees ABH, Reyes L, Schallenberg M, Shepherd C, Short J, Simon KS, Steiner K, Šunde C, Terezow M, Tibby J.
PMID: 34942258
Sci Total Environ. 2021 Dec 21;812:152385. doi: 10.1016/j.scitotenv.2021.152385. Epub 2021 Dec 21.

Lakes and their catchments have been subjected to centuries to millennia of exploitation by humans. Efficient monitoring methods are required to promote proactive protection and management. Traditional monitoring is time consuming and expensive, which limits the number of lakes...

A bacterial index to estimate lake trophic level: National scale validation.

The Science of the total environment

Pearman JK, Wood SA, Vandergoes MJ, Atalah J, Waters S, Adamson J, Thomson-Laing G, Thompson L, Howarth JD, Hamilton DP, Pochon X, Biessy L, Brasell KA, Dahl J, Ellison R, Fitzsimons SJ, Gard H, Gerrard T, Gregersen R, Holloway M, Li X, Kelly DJ, Martin R, McFarlane K, McKay NP, Moody A, Moy CM, Naeher S, Newnham R, Parai R, Picard M, Puddick J, Rees ABH, Reyes L, Schallenberg M, Shepherd C, Short J, Simon KS, Steiner K, Šunde C, Terezow M, Tibby J.
PMID: 34942258
Sci Total Environ. 2021 Dec 21;812:152385. doi: 10.1016/j.scitotenv.2021.152385. Epub 2021 Dec 21.

Lakes and their catchments have been subjected to centuries to millennia of exploitation by humans. Efficient monitoring methods are required to promote proactive protection and management. Traditional monitoring is time consuming and expensive, which limits the number of lakes...

Optimizing the treatment of acute lymphoblastic leukemia in younger and older adults: new drugs and evolving paradigms.

Leukemia

Short NJ, Kantarjian H, Jabbour E.
PMID: 34172894
Leukemia. 2021 Nov;35(11):3044-3058. doi: 10.1038/s41375-021-01277-3. Epub 2021 Jun 25.

In the past decade, the available treatments for patients with acute lymphoblastic leukemia (ALL) have rapidly expanded, in parallel with an increased understanding of the genomic features that impact the disease biology and clinical outcomes. With the development of...

Dietary Intake and Representativeness of a Diverse College-Attending Population Compared with an Age-Matched US Population.

Nutrients

Rana ZH, Frankenfeld CL, de Jonge L, Kennedy EJ, Bertoldo J, Short JL, Cheskin LJ.
PMID: 34836066
Nutrients. 2021 Oct 26;13(11). doi: 10.3390/nu13113810.

Young adults typically gain more dietary autonomy as they start college, though this can also present nutritional challenges; however, research on the generalizability of their dietary intake data is scarce. To address this representativeness concern, we compared food and...

A bacterial index to estimate lake trophic level: National scale validation.

The Science of the total environment

Pearman JK, Wood SA, Vandergoes MJ, Atalah J, Waters S, Adamson J, Thomson-Laing G, Thompson L, Howarth JD, Hamilton DP, Pochon X, Biessy L, Brasell KA, Dahl J, Ellison R, Fitzsimons SJ, Gard H, Gerrard T, Gregersen R, Holloway M, Li X, Kelly DJ, Martin R, McFarlane K, McKay NP, Moody A, Moy CM, Naeher S, Newnham R, Parai R, Picard M, Puddick J, Rees ABH, Reyes L, Schallenberg M, Shepherd C, Short J, Simon KS, Steiner K, Šunde C, Terezow M, Tibby J.
PMID: 34942258
Sci Total Environ. 2021 Dec 21;812:152385. doi: 10.1016/j.scitotenv.2021.152385. Epub 2021 Dec 21.

Lakes and their catchments have been subjected to centuries to millennia of exploitation by humans. Efficient monitoring methods are required to promote proactive protection and management. Traditional monitoring is time consuming and expensive, which limits the number of lakes...

Harnessing the benefits of available targeted therapies in acute myeloid leukaemia.

The Lancet. Haematology

Kantarjian H, Short NJ, DiNardo C, Stein EM, Daver N, Perl AE, Wang ES, Wei A, Tallman M.
PMID: 34687602
Lancet Haematol. 2021 Dec;8(12):e922-e933. doi: 10.1016/S2352-3026(21)00270-2. Epub 2021 Oct 20.

Research has resulted in regulatory approval of nine agents for acute myeloid leukaemia indications by the US Food and Drug Administration since 2017: the Bcl-2 inhibitor, venetoclax; two FLT3 inhibitors, midostaurin and gilteritinib; two IDH inhibitors, ivosidenib (IDH1 inhibitor)...

A cross-species assay demonstrates that reward responsiveness is enduringly impacted by adverse, unpredictable early-life experiences.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Kangas BD, Short AK, Luc OT, Stern HS, Baram TZ, Pizzagalli DA.
PMID: 34921225
Neuropsychopharmacology. 2021 Dec 17; doi: 10.1038/s41386-021-01250-9. Epub 2021 Dec 17.

Exposure to early-life adversity (ELA) is associated with several neuropsychiatric conditions, including major depressive disorder, yet causality is difficult to establish in humans. Recent work in rodents has implicated impaired reward circuit signaling in anhedonic-like behavior after ELA exposure....

Emergence of .

Frontiers in oncology

Alotaibi AS, Yilmaz M, Loghavi S, DiNardo C, Borthakur G, Kadia TM, Thakral B, Pemmaraju N, Issa GC, Konopleva M, Short NJ, Patel K, Tang G, Ravandi F, Daver N.
PMID: 33194747
Front Oncol. 2020 Oct 20;10:588876. doi: 10.3389/fonc.2020.588876. eCollection 2020.

Despite the promising result with FLT3 inhibitors in AML, the emergence of resistance poses a significant challenge, leading to a shorter response duration and inferior survival. This is frequently driven by on-target or parallel prosurvival mutations. The emergence of

Correction to: The help for people with money, employment or housing problems (HOPE) intervention: pilot randomised trial with mixed methods feasibility research.

Pilot and feasibility studies

Barnes MC, Haase AM, Scott LJ, Linton MJ, Bard AM, Donovan JL, Davies R, Dursley S, Williams S, Elliott D, Potokar J, Kapur N, Hawton K, O'Connor RC, Hollingworth W, Metcalfe C, Gunnell D.
PMID: 30505459
Pilot Feasibility Stud. 2018 Nov 28;4:177. doi: 10.1186/s40814-018-0374-5. eCollection 2018.

[This corrects the article DOI: 10.1186/s40814-018-0365-6.].

Evaluation and management of measurable residual disease in acute lymphoblastic leukemia.

Therapeutic advances in hematology

Abou Dalle I, Jabbour E, Short NJ.
PMID: 32215194
Ther Adv Hematol. 2020 Mar 06;11:2040620720910023. doi: 10.1177/2040620720910023. eCollection 2020.

With standard chemotherapy regimens for adults with acute lymphoblastic leukemia, approximately 90% of patients achieve complete remission. However, up to half of patients have persistent minimal/measurable residual disease (MRD) not recognized by routine microscopy, which constitutes the leading determinant...

Showing 25 to 36 of 262 entries