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Showing 25 to 36 of 198 entries
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Covid-19 and smart beta: A case study on the role of sectors.

Financial markets and portfolio management

Hasaj M, Scherer B.
PMID: 34765080
Financ Mark Portf Mang. 2021 Apr 15;1-18. doi: 10.1007/s11408-021-00383-7. Epub 2021 Apr 15.

We investigate the role of sectors on the performance of smart beta products during the COVID-19 crisis. Cross-sectional differences in excess returns (versus a market capitalized portfolio) are driven by strong exposures to COVID-19-related industry rotation, rather than to...

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Hasaj M, Scherer B. Covid-19 and smart beta: A case study on the role of sectors. Financ Mark Portf Mang. 2021;1-18doi: 10.1007/s11408-021-00383-7.
Hasaj, M., & Scherer, B. (2021). Covid-19 and smart beta: A case study on the role of sectors. Financial markets and portfolio management, 1-18. https://doi.org/10.1007/s11408-021-00383-7
Hasaj, Milot, and Scherer, Bernd. "Covid-19 and smart beta: A case study on the role of sectors." Financial markets and portfolio management vol. (2021): 1-18. doi: https://doi.org/10.1007/s11408-021-00383-7
Hasaj M, Scherer B. Covid-19 and smart beta: A case study on the role of sectors. Financ Mark Portf Mang. 2021 Apr 15;1-18. doi: 10.1007/s11408-021-00383-7. Epub 2021 Apr 15. PMID: 34765080; PMCID: PMC8049398.
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The metabolic syndrome, thiazolidinediones, and implications for intersection of chronic and inflammatory disease.

Molecular metabolism

Colca JR, Scherer PE.
PMID: 34863942
Mol Metab. 2021 Dec 01;55:101409. doi: 10.1016/j.molmet.2021.101409. Epub 2021 Dec 01.

BACKGROUND: Chronic disease appears connected to obesity. However, evidence suggests that chronic metabolic diseases are more specifically related to adipose dysfunction rather than to body weight itself.SCOPE OF REVIEW: Further study of the first generation "insulin sensitizer" pioglitazone and...

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Colca JR, Scherer PE. The metabolic syndrome, thiazolidinediones, and implications for intersection of chronic and inflammatory disease. Mol Metab. 2021;55:101409doi: 10.1016/j.molmet.2021.101409.
Colca, J. R., & Scherer, P. E. (2021). The metabolic syndrome, thiazolidinediones, and implications for intersection of chronic and inflammatory disease. Molecular metabolism, 55101409. https://doi.org/10.1016/j.molmet.2021.101409
Colca, Jerry R, and Scherer, Philipp E. "The metabolic syndrome, thiazolidinediones, and implications for intersection of chronic and inflammatory disease." Molecular metabolism vol. 55 (2021): 101409. doi: https://doi.org/10.1016/j.molmet.2021.101409
Colca JR, Scherer PE. The metabolic syndrome, thiazolidinediones, and implications for intersection of chronic and inflammatory disease. Mol Metab. 2021 Dec 01;55:101409. doi: 10.1016/j.molmet.2021.101409. Epub 2021 Dec 01. PMID: 34863942; PMCID: PMC8688722.
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Comparability of The Netherlands Physical Activity Questionnaire with Accelerometer-Measured Physical Activity in Samoan Children: A Retrospective Analysis of .

International journal of environmental research and public health

Warmath CR, Choy CC, Frame EA, Sherar LB, Duckham RL, Soti-Ulberg C, Naseri T, Reupena MS, Hawley NL.
PMID: 34444185
Int J Environ Res Public Health. 2021 Aug 10;18(16). doi: 10.3390/ijerph18168438.

Accurate measurement of physical activity is critical to understand its role in cardiometabolic health and obesity development in children and to monitor trends in behavior and evaluate interventions. An ongoing mixed-longitudinal study of child growth and development in Samoa...

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Warmath CR, Choy CC, Frame EA, et al. Comparability of The Netherlands Physical Activity Questionnaire with Accelerometer-Measured Physical Activity in Samoan Children: A Retrospective Analysis of . Int J Environ Res Public Health. 2021;18(16)doi: 10.3390/ijerph18168438.
Warmath, C. R., Choy, C. C., Frame, E. A., Sherar, L. B., Duckham, R. L., Soti-Ulberg, C., Naseri, T., Reupena, M. S., & Hawley, N. L. (2021). Comparability of The Netherlands Physical Activity Questionnaire with Accelerometer-Measured Physical Activity in Samoan Children: A Retrospective Analysis of . International journal of environmental research and public health, 18(16), . https://doi.org/10.3390/ijerph18168438
Warmath, Clara R, et al. "Comparability of The Netherlands Physical Activity Questionnaire with Accelerometer-Measured Physical Activity in Samoan Children: A Retrospective Analysis of ." International journal of environmental research and public health vol. 18,16 (2021). doi: https://doi.org/10.3390/ijerph18168438
Warmath CR, Choy CC, Frame EA, Sherar LB, Duckham RL, Soti-Ulberg C, Naseri T, Reupena MS, Hawley NL. Comparability of The Netherlands Physical Activity Questionnaire with Accelerometer-Measured Physical Activity in Samoan Children: A Retrospective Analysis of . Int J Environ Res Public Health. 2021 Aug 10;18(16). doi: 10.3390/ijerph18168438. PMID: 34444185; PMCID: PMC8391931.
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PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart.

Circulation

Li Q, Li C, Elnwasany A, Sharma G, An YA, Zhang G, Elhelaly WM, Lin J, Gong Y, Chen G, Wang M, Zhao S, Dai C, Smart CD, Liu J, Luo X, Deng Y, Tan L, Lv SJ, Davidson SM, Locasale JW, Lorenzi PL, Malloy CR, Gillette TG, Vander Heiden MG, Scherer PE, Szweda LI, Fu G, Wang ZV.
PMID: 34102853
Circulation. 2021 Aug 31;144(9):712-727. doi: 10.1161/CIRCULATIONAHA.121.054885. Epub 2021 Jun 09.

BACKGROUND: Metabolic remodeling precedes most alterations during cardiac hypertrophic growth under hemodynamic stress. The elevation of glucose utilization has been recognized as a hallmark of metabolic remodeling. However, its role in cardiac hypertrophic growth and heart failure in response...

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Li Q, Li C, Elnwasany A, et al. PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart. Circulation. 2021;144(9):712-727doi: 10.1161/CIRCULATIONAHA.121.054885.
Li, Q., Li, C., Elnwasany, A., Sharma, G., An, Y. A., Zhang, G., Elhelaly, W. M., Lin, J., Gong, Y., Chen, G., Wang, M., Zhao, S., Dai, C., Smart, C. D., Liu, J., Luo, X., Deng, Y., Tan, L., Lv, S. J., Davidson, S. M., Locasale, J. W., Lorenzi, P. L., Malloy, C. R., Gillette, T. G., Vander Heiden, M. G., Scherer, P. E., Szweda, L. I., Fu, G., & Wang, Z. V. (2021). PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart. Circulation, 144(9), 712-727. https://doi.org/10.1161/CIRCULATIONAHA.121.054885
Li, Qinfeng, et al. "PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart." Circulation vol. 144,9 (2021): 712-727. doi: https://doi.org/10.1161/CIRCULATIONAHA.121.054885
Li Q, Li C, Elnwasany A, Sharma G, An YA, Zhang G, Elhelaly WM, Lin J, Gong Y, Chen G, Wang M, Zhao S, Dai C, Smart CD, Liu J, Luo X, Deng Y, Tan L, Lv SJ, Davidson SM, Locasale JW, Lorenzi PL, Malloy CR, Gillette TG, Vander Heiden MG, Scherer PE, Szweda LI, Fu G, Wang ZV. PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart. Circulation. 2021 Aug 31;144(9):712-727. doi: 10.1161/CIRCULATIONAHA.121.054885. Epub 2021 Jun 09. PMID: 34102853; PMCID: PMC8405569.
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Discovery of 4-aminopyrimidine analogs as highly potent dual P70S6K/Akt inhibitors.

Bioorganic & medicinal chemistry letters

Xiao Y, Huck BR, Lan R, DeSelm L, Chen X, Qiu H, Neagu C, Johnson T, Mochalkin I, Gardberg A, Jiang X, Tian H, Dutt V, Santos D, Head J, Jackson J, Syed S, Lin J, Wilker E, Ma J, Clark A, Machl A, Bankston D, Jones CCV, Goutopoulos A, Sherer B.
PMID: 34481987
Bioorg Med Chem Lett. 2021 Oct 15;50:128352. doi: 10.1016/j.bmcl.2021.128352. Epub 2021 Sep 02.

Activation of the PI3K/Akt/mTOR kinase pathway is associated with human cancers. A dual p70S6K/Akt inhibitor is sufficient to inhibit strong tumor growth and to block negative impact of the compensatory Akt feedback loop activation. A scaffold docking strategy based...

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Xiao Y, Huck BR, Lan R, et al. Discovery of 4-aminopyrimidine analogs as highly potent dual P70S6K/Akt inhibitors. Bioorg Med Chem Lett. 2021;50:128352doi: 10.1016/j.bmcl.2021.128352.
Xiao, Y., Huck, B. R., Lan, R., DeSelm, L., Chen, X., Qiu, H., Neagu, C., Johnson, T., Mochalkin, I., Gardberg, A., Jiang, X., Tian, H., Dutt, V., Santos, D., Head, J., Jackson, J., Syed, S., Lin, J., Wilker, E., Ma, J., Clark, A., Machl, A., Bankston, D., Jones, C. C. V., Goutopoulos, A., & Sherer, B. (2021). Discovery of 4-aminopyrimidine analogs as highly potent dual P70S6K/Akt inhibitors. Bioorganic & medicinal chemistry letters, 50128352. https://doi.org/10.1016/j.bmcl.2021.128352
Xiao, Yufang, et al. "Discovery of 4-aminopyrimidine analogs as highly potent dual P70S6K/Akt inhibitors." Bioorganic & medicinal chemistry letters vol. 50 (2021): 128352. doi: https://doi.org/10.1016/j.bmcl.2021.128352
Xiao Y, Huck BR, Lan R, DeSelm L, Chen X, Qiu H, Neagu C, Johnson T, Mochalkin I, Gardberg A, Jiang X, Tian H, Dutt V, Santos D, Head J, Jackson J, Syed S, Lin J, Wilker E, Ma J, Clark A, Machl A, Bankston D, Jones CCV, Goutopoulos A, Sherer B. Discovery of 4-aminopyrimidine analogs as highly potent dual P70S6K/Akt inhibitors. Bioorg Med Chem Lett. 2021 Oct 15;50:128352. doi: 10.1016/j.bmcl.2021.128352. Epub 2021 Sep 02. PMID: 34481987.
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Skin aging as a mechanical phenomenon: The main weak links.

Nutrition and healthy aging

Kruglikov IL, Scherer PE.
PMID: 29951590
Nutr Healthy Aging. 2018 Jun 15;4(4):291-307. doi: 10.3233/NHA-170037.

From a mechanical point of view, human skin appears as a layered composite containing the stiff thin cover layer presented by the stratum corneum, below which are the more compliant layers of viable epidermis and dermis and further below...

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Kruglikov IL, Scherer PE. Skin aging as a mechanical phenomenon: The main weak links. Nutr Healthy Aging. 2018;4(4):291-307doi: 10.3233/NHA-170037.
Kruglikov, I. L., & Scherer, P. E. (2018). Skin aging as a mechanical phenomenon: The main weak links. Nutrition and healthy aging, 4(4), 291-307. https://doi.org/10.3233/NHA-170037
Kruglikov, Ilja L, and Scherer, Philipp E. "Skin aging as a mechanical phenomenon: The main weak links." Nutrition and healthy aging vol. 4,4 (2018): 291-307. doi: https://doi.org/10.3233/NHA-170037
Kruglikov IL, Scherer PE. Skin aging as a mechanical phenomenon: The main weak links. Nutr Healthy Aging. 2018 Jun 15;4(4):291-307. doi: 10.3233/NHA-170037. PMID: 29951590; PMCID: PMC6004930.
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Screen-time during the after-school period: A contextual perspective.

Preventive medicine reports

Haycraft E, Sherar LB, Griffiths P, Biddle SJH, Pearson N.
PMID: 32455103
Prev Med Rep. 2020 May 08;19:101116. doi: 10.1016/j.pmedr.2020.101116. eCollection 2020 Sep.

Sedentary screen-time is an increasingly prevalent behaviour, associated with a range of adverse health outcomes. Sedentary time and screen-use increase during adolescence, making this age group a prime target for behaviour change interventions. Better understanding the context in which...

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Haycraft E, Sherar LB, Griffiths P, et al. Screen-time during the after-school period: A contextual perspective. Prev Med Rep. 2020;19:101116doi: 10.1016/j.pmedr.2020.101116.
Haycraft, E., Sherar, L. B., Griffiths, P., Biddle, S. J. H., & Pearson, N. (2020). Screen-time during the after-school period: A contextual perspective. Preventive medicine reports, 19101116. https://doi.org/10.1016/j.pmedr.2020.101116
Haycraft, Emma, et al. "Screen-time during the after-school period: A contextual perspective." Preventive medicine reports vol. 19 (2020): 101116. doi: https://doi.org/10.1016/j.pmedr.2020.101116
Haycraft E, Sherar LB, Griffiths P, Biddle SJH, Pearson N. Screen-time during the after-school period: A contextual perspective. Prev Med Rep. 2020 May 08;19:101116. doi: 10.1016/j.pmedr.2020.101116. eCollection 2020 Sep. PMID: 32455103; PMCID: PMC7236051.
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Correction to: The role of fat on cardiomyopathy outcome in mouse models of chronic Trypanosoma cruzi infection.

Parasitology research

Zaki P, Domingues ELBC, Amjad FM, Narde MB, Gonçalves KR, Viana ML, de Paula H, de Lima WG, Huang H, Bahia MT, Scherer PE, Dos Santos FM, Weiss LM, Tanowitz HB.
PMID: 32307581
Parasitol Res. 2020 Jun;119(6):1845. doi: 10.1007/s00436-020-06685-5.

The authors regret that Philipp E Scherer's name was spelt incorrectly in the author list. The name of the author is now corrected above.

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Zaki P, Domingues ELBC, Amjad FM, et al. Correction to: The role of fat on cardiomyopathy outcome in mouse models of chronic Trypanosoma cruzi infection. Parasitol Res. 2020;119(6):1845doi: 10.1007/s00436-020-06685-5.
Zaki, P., Domingues, E. L. B. C., Amjad, F. M., Narde, M. B., Gonçalves, K. R., Viana, M. L., de Paula, H., de Lima, W. G., Huang, H., Bahia, M. T., Scherer, P. E., Dos Santos, F. M., Weiss, L. M., & Tanowitz, H. B. (2020). Correction to: The role of fat on cardiomyopathy outcome in mouse models of chronic Trypanosoma cruzi infection. Parasitology research, 119(6), 1845. https://doi.org/10.1007/s00436-020-06685-5
Zaki, Paul, et al. "Correction to: The role of fat on cardiomyopathy outcome in mouse models of chronic Trypanosoma cruzi infection." Parasitology research vol. 119,6 (2020): 1845. doi: https://doi.org/10.1007/s00436-020-06685-5
Zaki P, Domingues ELBC, Amjad FM, Narde MB, Gonçalves KR, Viana ML, de Paula H, de Lima WG, Huang H, Bahia MT, Scherer PE, Dos Santos FM, Weiss LM, Tanowitz HB. Correction to: The role of fat on cardiomyopathy outcome in mouse models of chronic Trypanosoma cruzi infection. Parasitol Res. 2020 Jun;119(6):1845. doi: 10.1007/s00436-020-06685-5. PMID: 32307581.
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PEGylated AdipoRon derivatives improve glucose and lipid metabolism under insulinopenic and high-fat diet conditions.

Journal of lipid research

Onodera T, Ghazvini Zadeh E, Xu P, Gordillo R, Guo Z, Joffin N, Yu B, Scherer PE, Li WH.
PMID: 34214600
J Lipid Res. 2021;62:100095. doi: 10.1016/j.jlr.2021.100095. Epub 2021 Jun 30.

The pleiotropic actions of adiponectin in improving cell survival and metabolism have motivated the development of small-molecule therapeutic agents for treating diabetes and lipotoxicity. AdipoRon is a synthetic agonist of the adiponectin receptors, yet is limited by its poor...

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Onodera T, Ghazvini Zadeh E, Xu P, et al. PEGylated AdipoRon derivatives improve glucose and lipid metabolism under insulinopenic and high-fat diet conditions. J Lipid Res. 2021;62:100095doi: 10.1016/j.jlr.2021.100095.
Onodera, T., Ghazvini Zadeh, E., Xu, P., Gordillo, R., Guo, Z., Joffin, N., Yu, B., Scherer, P. E., & Li, W. H. (2021). PEGylated AdipoRon derivatives improve glucose and lipid metabolism under insulinopenic and high-fat diet conditions. Journal of lipid research, 62100095. https://doi.org/10.1016/j.jlr.2021.100095
Onodera, Toshiharu, et al. "PEGylated AdipoRon derivatives improve glucose and lipid metabolism under insulinopenic and high-fat diet conditions." Journal of lipid research vol. 62 (2021): 100095. doi: https://doi.org/10.1016/j.jlr.2021.100095
Onodera T, Ghazvini Zadeh E, Xu P, Gordillo R, Guo Z, Joffin N, Yu B, Scherer PE, Li WH. PEGylated AdipoRon derivatives improve glucose and lipid metabolism under insulinopenic and high-fat diet conditions. J Lipid Res. 2021;62:100095. doi: 10.1016/j.jlr.2021.100095. Epub 2021 Jun 30. PMID: 34214600; PMCID: PMC8327158.
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Cross-sectional associations between domain-specific sitting time and other lifestyle health behaviours: the Stormont study.

Journal of public health (Oxford, England)

Kettle VE, Hamer M, Munir F, Houdmont J, Wilson K, Kerr R, Addley K, Sherar LB, Clemes SA.
PMID: 34343313
J Public Health (Oxf). 2021 Aug 03; doi: 10.1093/pubmed/fdab298. Epub 2021 Aug 03.

BACKGROUND: There is a dearth of literature on how different domains of sitting time relate to other health behaviours. Therefore, this study aimed to explore these associations in a sample of office workers.METHODS: 7170 Northern Irish Civil Servants completed...

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Kettle VE, Hamer M, Munir F, et al. Cross-sectional associations between domain-specific sitting time and other lifestyle health behaviours: the Stormont study. J Public Health (Oxf). 2021;doi: 10.1093/pubmed/fdab298.
Kettle, V. E., Hamer, M., Munir, F., Houdmont, J., Wilson, K., Kerr, R., Addley, K., Sherar, L. B., & Clemes, S. A. (2021). Cross-sectional associations between domain-specific sitting time and other lifestyle health behaviours: the Stormont study. Journal of public health (Oxford, England), . https://doi.org/10.1093/pubmed/fdab298
Kettle, Victoria E, et al. "Cross-sectional associations between domain-specific sitting time and other lifestyle health behaviours: the Stormont study." Journal of public health (Oxford, England) vol. (2021). doi: https://doi.org/10.1093/pubmed/fdab298
Kettle VE, Hamer M, Munir F, Houdmont J, Wilson K, Kerr R, Addley K, Sherar LB, Clemes SA. Cross-sectional associations between domain-specific sitting time and other lifestyle health behaviours: the Stormont study. J Public Health (Oxf). 2021 Aug 03; doi: 10.1093/pubmed/fdab298. Epub 2021 Aug 03. PMID: 34343313.
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Mouse Adipose Tissue Protein Extraction.

Bio-protocol

An YA, Scherer PE.
PMID: 33659303
Bio Protoc. 2020 Jun 05;10(11):e3631. doi: 10.21769/BioProtoc.3631. eCollection 2020 Jun 05.

As obesity becomes a global epidemic, the metabolism research field is increasingly focusing on studying the physiological and pathological roles of adipose tissues (AT). However, extracting proteins from AT is challenging due to abundant fat content of intracellular lipid...

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An YA, Scherer PE. Mouse Adipose Tissue Protein Extraction. Bio Protoc. 2020;10(11):e3631doi: 10.21769/BioProtoc.3631.
An, Y. A., & Scherer, P. E. (2020). Mouse Adipose Tissue Protein Extraction. Bio-protocol, 10(11), e3631. https://doi.org/10.21769/BioProtoc.3631
An, Yu A, and Scherer, Philipp E. "Mouse Adipose Tissue Protein Extraction." Bio-protocol vol. 10,11 (2020): e3631. doi: https://doi.org/10.21769/BioProtoc.3631
An YA, Scherer PE. Mouse Adipose Tissue Protein Extraction. Bio Protoc. 2020 Jun 05;10(11):e3631. doi: 10.21769/BioProtoc.3631. eCollection 2020 Jun 05. PMID: 33659303; PMCID: PMC7842653.
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Current Perspectives of Prenatal Sonographic Diagnosis and Clinical Management Challenges of Nuchal Cord(s).

International journal of women's health

Sherer DM, Ward K, Bennett M, Dalloul M.
PMID: 32982473
Int J Womens Health. 2020 Aug 10;12:613-631. doi: 10.2147/IJWH.S211124. eCollection 2020.

Umbilical cord accidents preceding labor are uncommon. In contrast, nuchal cords are a very common finding at delivery, with reported incidences of a single nuchal cord of approximately between 20% and 35% of all singleton deliveries at term. Multiple...

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Sherer DM, Ward K, Bennett M, et al. Current Perspectives of Prenatal Sonographic Diagnosis and Clinical Management Challenges of Nuchal Cord(s). Int J Womens Health. 2020;12:613-631doi: 10.2147/IJWH.S211124.
Sherer, D. M., Ward, K., Bennett, M., & Dalloul, M. (2020). Current Perspectives of Prenatal Sonographic Diagnosis and Clinical Management Challenges of Nuchal Cord(s). International journal of women's health, 12613-631. https://doi.org/10.2147/IJWH.S211124
Sherer, David M, et al. "Current Perspectives of Prenatal Sonographic Diagnosis and Clinical Management Challenges of Nuchal Cord(s)." International journal of women's health vol. 12 (2020): 613-631. doi: https://doi.org/10.2147/IJWH.S211124
Sherer DM, Ward K, Bennett M, Dalloul M. Current Perspectives of Prenatal Sonographic Diagnosis and Clinical Management Challenges of Nuchal Cord(s). Int J Womens Health. 2020 Aug 10;12:613-631. doi: 10.2147/IJWH.S211124. eCollection 2020. PMID: 32982473; PMCID: PMC7500175.
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Showing 25 to 36 of 198 entries