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Showing 13 to 24 of 198 entries
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Relationship between Changes in Plasma Adiponectin Concentration and Insulin Sensitivity after Niacin Therapy.

Cardiorenal medicine

Fraterrigo G, Fabbrini E, Mittendorfer B, O'Rahilly S, Scherer PE, Patterson BW, Klein S.
PMID: 22969777
Cardiorenal Med. 2012 Aug;2(3):211-217. doi: 10.1159/000340037. Epub 2012 Jul 18.

BACKGROUND: Niaspan® (extended-release niacin) is a nicotinic acid formulation used to treat dyslipidemia in obese subjects. Niaspan binds to the GPR109A receptor in adipose tissue and stimulates adiponectin secretion, which should improve insulin sensitivity. However, Niaspan therapy often causes...

An elusive blind-thrust fault beneath metropolitan los angeles .

Science (New York, N.Y.)

Shaw JH, Shearer PM.
PMID: 10066170
Science. 1999 Mar 05;283(5407):1516-8. doi: 10.1126/science.283.5407.1516.

Seismic reflection profiles, petroleum wells, and relocated earthquakes reveal the presence of an active blind-thrust fault beneath metropolitan Los Angeles. A segment of this fault likely caused the 1987 Whittier Narrows (magnitude 6.0) earthquake. Mapped sizes of other fault...

Caveolin-1 as a pathophysiological factor and target in psoriasis.

NPJ aging and mechanisms of disease

Kruglikov IL, Scherer PE.
PMID: 30729030
NPJ Aging Mech Dis. 2019 Feb 05;5:4. doi: 10.1038/s41514-019-0034-x. eCollection 2019.

Low expression of caveolin-1 (Cav-1) is typical in psoriatic lesions and overexpression of Cav-1 leads to a reduction of inflammation and suppression of epidermal hyperproliferation, thus ameliorating these two well-known hallmarks of psoriasis. At the same time, the interfacial...

Simulated Optimum Sowing Date for Forage Pearl Millet Cultivars in Multilocation Trials in Brazilian Semi-Arid Region.

Frontiers in plant science

Santos RD, Boote KJ, Sollenberger LE, Neves ALA, Pereira LGR, Scherer CB, Gonçalves LC.
PMID: 29276521
Front Plant Sci. 2017 Dec 08;8:2074. doi: 10.3389/fpls.2017.02074. eCollection 2017.

Forage production is primarily limited by weather conditions under dryland production systems in Brazilian semi-arid regions, therefore sowing at the appropriate time is critical. The objectives of this study were to evaluate the CSM-CERES-Pearl Millet model from the DSSAT...

A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions.

Chemical science

Ji Y, Li H, Hyde AM, Chen Q, Belyk KM, Lexa KW, Yin J, Sherer EC, Williamson RT, Brunskill A, Ren S, Campeau LC, Davies IW, Ruck RT.
PMID: 28553522
Chem Sci. 2017 Apr 01;8(4):2841-2851. doi: 10.1039/c6sc05472b. Epub 2017 Jan 19.

Significant catalyst loading reduction and increased reaction robustness have been achieved for a Pd-catalyzed asymmetric intramolecular C-N coupling through comprehensive mechanistic studies. Detailed kinetic, spectroscopic, and crystallographic analyses revealed that the mono-oxidation of the bis-phosphine ligand is critical for...

A review of the Best Practice in Radiation Oncology project from 2008 to 2018.

Technical innovations & patient support in radiation oncology

Coffey M, Rosenblatt E, Vandevelde G, Osztavics A, Pasini D, Scherer P, Dickie C, Karadza V, Van Egten V, Leech M.
PMID: 32095580
Tech Innov Patient Support Radiat Oncol. 2018 Nov 13;8:3-7. doi: 10.1016/j.tipsro.2018.09.002. eCollection 2018 Dec.

The European Society of Radiotherapy and Oncology (ESTRO)/International Atomic Energy Agency (IAEA) Best Practice in Radiation Oncology-a project to train RTT trainers has reached its ten year anniversary and will commence its fifth iteration in 2018. This project commenced...

Life history stage explains behavior in a social network before and during the early breeding season in a cooperatively breeding bird.

PeerJ

Tringali A, Sherer DL, Cosgrove J, Bowman R.
PMID: 32095315
PeerJ. 2020 Feb 10;8:e8302. doi: 10.7717/peerj.8302. eCollection 2020.

In species with stage-structured populations selection pressures may vary between different life history stages and result in stage-specific behaviors. We use life history stage to explain variation in the pre and early breeding season social behavior of a cooperatively...

The metabolic syndrome, thiazolidinediones, and implications for intersection of chronic and inflammatory disease.

Molecular metabolism

Colca JR, Scherer PE.
PMID: 34863942
Mol Metab. 2021 Dec 01;55:101409. doi: 10.1016/j.molmet.2021.101409. Epub 2021 Dec 01.

BACKGROUND: Chronic disease appears connected to obesity. However, evidence suggests that chronic metabolic diseases are more specifically related to adipose dysfunction rather than to body weight itself.SCOPE OF REVIEW: Further study of the first generation "insulin sensitizer" pioglitazone and...

Assessment of skeletal age in youth female soccer players: Agreement between Greulich-Pyle and Fels protocols.

American journal of human biology : the official journal of the Human Biology Council

Martinho DV, Coelho-E-Silva MJ, Valente-Dos-Santos J, Minderico C, Oliveira TG, Rodrigues I, Conde J, Sherar LB, Malina RM.
PMID: 33749124
Am J Hum Biol. 2021 Mar 21;e23591. doi: 10.1002/ajhb.23591. Epub 2021 Mar 21.

OBJECTIVE: The purpose of the study was to evaluate the agreement between the Fels and Greulich-Pyle methods for the assessment of skeletal age (SA) in female youth soccer players.METHODS: The sample included 441 Portuguese players 10.08-16.73 years of age...

Adiponectin and cardiometabolic trait and mortality: where do we go?.

Cardiovascular research

Jang AY, Scherer PE, Kim JY, Lim S, Koh KK.
PMID: 34117867
Cardiovasc Res. 2021 Jun 12; doi: 10.1093/cvr/cvab199. Epub 2021 Jun 12.

Adiponectin is an adipocyte-derived cytokine known for its cardioprotective effects in preclinical studies. Early epidemiologic studies replicated these findings and drew great interest. Subsequent large-scale prospective cohorts, however, showed that adiponectin levels seemed not to relate to incident coronary...

Obesity, Diabetes, and Increased Cancer Progression.

Diabetes & metabolism journal

Kim DS, Scherer PE.
PMID: 34847640
Diabetes Metab J. 2021 Nov;45(6):799-812. doi: 10.4093/dmj.2021.0077. Epub 2021 Nov 22.

Rates of obesity and diabetes have increased significantly over the past decades and the prevalence is expected to continue to rise further in the coming years. Many observations suggest that obesity and diabetes are associated with an increased risk...

Mid-trimester isolated bilateral rocker bottom feet leading to prenatal diagnosis of 7q11.23 microdeletion: Williams syndrome.

Journal of ultrasound

Sherer DM, Hsieh V, Granderson F, Yusuf H, Dalloul M.
PMID: 35001324
J Ultrasound. 2022 Jan 10; doi: 10.1007/s40477-021-00638-z. Epub 2022 Jan 10.

Prenatal sonographic depiction of congenital vertical talus (rocker bottom feet), describing a prominent calcaneus and rounded convex appearance of the ventral aspect of the foot, has been reported with fetal Trisomies 18, 13, 9 HOXD10 mutations and recently 2q13...

Showing 13 to 24 of 198 entries