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Showing 13 to 24 of 27 entries
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Attenuation of Vaccinia Virus.

Acta naturae

Yakubitskiy SN, Kolosova IV, Maksyutov RA, Shchelkunov SN.
PMID: 26798498
Acta Naturae. 2015 Oct-Dec;7(4):113-21.

Since 1980, in the post-smallpox vaccination era the human population has become increasingly susceptible compared to a generation ago to not only the variola (smallpox) virus, but also other zoonotic orthopoxviruses. The need for safer vaccines against orthopoxviruses is...

Complete Genome Sequence of Sterol-Transforming Mycobacterium neoaurum Strain VKM Ac-1815D.

Genome announcements

Shtratnikova VY, Bragin EY, Dovbnya DV, Pekov YA, Schelkunov MI, Strizhov N, Ivashina TV, Ashapkin VV, Donova MV.
PMID: 24435872
Genome Announc. 2014 Jan 16;2(1). doi: 10.1128/genomeA.01177-13.

Mycobacterium neoaurum strain VKM Ac-1815D produces 4-androstene-3,17-dione as a major compound from phytosterols. Here, we report the complete genome sequence of the strain. The genome consists of a single circular 5,438,190-bp chromosome, with a G+C content of 66.88%, containing...

Adjuvant-Induced Arthritis in Guinea Pigs.

Acta naturae

Taranov OS, Yakubitskiy SN, Nepomnyashchikh TS, Nesterov AE, Shchelkunov SN.
PMID: 28050272
Acta Naturae. 2016 Oct-Dec;8(4):110-117.

We propose a model of rheumatoid arthritis (RA) induced in outbred guinea pigs using a single subcutaneous injection of complete Freund's adjuvant to the hind paw. Histological examination of this model shows fibrin deposition on the surface of the...

Comparing New-Generation Candidate Vaccines against Human Orthopoxvirus Infections.

Acta naturae

Maksyutov RA, Yakubitskyi SN, Kolosova IV, Shchelkunov SN.
PMID: 28740731
Acta Naturae. 2017 Apr-Jun;9(2):88-93.

The lack of immunity to the variola virus in the population, increasingly more frequent cases of human orthopoxvirus infection, and increased risk of the use of the variola virus (VARV) as a bioterrorism agent call for the development of...

PeerJ

Schelkunov MI, Nuraliev MS, Logacheva MD.
PMID: 31565552
PeerJ. 2019 Sep 12;7:e7500. doi: 10.7717/peerj.7500. eCollection 2019.

Although most plant species are photosynthetic, several hundred species have lost the ability to photosynthesize and instead obtain nutrients via various types of heterotrophic feeding. Their plastid genomes markedly differ from the plastid genomes of photosynthetic plants. In this...

Complete genome assembly data of .

Data in brief

Shtratnikova VY, Rudenskaya YA, Gerasimov ES, Schelkunov MI, Logacheva MD, Kolesnikov AA.
PMID: 32793774
Data Brief. 2020 Jul 25;32:106070. doi: 10.1016/j.dib.2020.106070. eCollection 2020 Oct.

An unknown bacterial strain was detected in the cytostome of

Complete Genome Sequence of Steroid-Transforming Nocardioides simplex VKM Ac-2033D.

Genome announcements

Shtratnikova VY, Schelkunov MI, Pekov YA, Fokina VV, Logacheva MD, Sokolov SL, Bragin EY, Ashapkin VV, Donova MV.
PMID: 25573942
Genome Announc. 2015 Jan 08;3(1). doi: 10.1128/genomeA.01406-14.

Nocardioides simplex VKM Ac-2033D is an effective microbial catalyst for 3-ketosteroid 1(2)-dehydrogenation, and it is capable of effective reduction of carbonyl groups at C-17 and C-20, hydrolysis of acetylated steroids, and utilization of natural sterols. Here, the complete genome...

SECRET domain of variola virus CrmB protein can be a member of poxviral type II chemokine-binding proteins family.

BMC research notes

Antonets DV, Nepomnyashchikh TS, Shchelkunov SN.
PMID: 20979600
BMC Res Notes. 2010 Oct 27;3:271. doi: 10.1186/1756-0500-3-271.

BACKGROUND: Variola virus (VARV) the causative agent of smallpox, eradicated in 1980, have wide spectrum of immunomodulatory proteins to evade host immunity. Recently additional biological activity was discovered for VARV CrmB protein, known to bind and inhibit tumour necrosis...

Corrigendum to "Comparative analysis of genes encoding key steroid core oxidation enzymes in fast-growing Mycobacterium spp. strains" [J. Steroid Biochem. Mol. Biol. 138 (2013) 41-53].

The Journal of steroid biochemistry and molecular biology

Bragin EY, Shtratnikova VY, Dovbnya DV, Schelkunov MI, Pekov YA, Malakho SG, Egorova OV, Ivashina TV, Sokolov SL, Ashapkin VV, Donova MV.
PMID: 32408066
J Steroid Biochem Mol Biol. 2020 Jun;200:105666. doi: 10.1016/j.jsbmb.2020.105666. Epub 2020 May 11.

No abstract available.

Genomic comparison of non-photosynthetic plants from the family Balanophoraceae with their photosynthetic relatives.

PeerJ

Schelkunov MI, Nuraliev MS, Logacheva MD.
PMID: 34540375
PeerJ. 2021 Aug 31;9:e12106. doi: 10.7717/peerj.12106. eCollection 2021.

The plant family Balanophoraceae consists entirely of species that have lost the ability to photosynthesize. Instead, they obtain nutrients by parasitizing other plants. Recent studies have revealed that plastid genomes of Balanophoraceae exhibit a number of interesting features, one...

Orthopoxvirus genes that mediate disease virulence and host tropism.

Advances in virology

Shchelkunov SN.
PMID: 22899927
Adv Virol. 2012;2012:524743. doi: 10.1155/2012/524743. Epub 2012 Jul 30.

In the course of evolution, viruses have developed various molecular mechanisms to evade the defense reactions of the host organism. When understanding the mechanisms used by viruses to overcome manifold defense systems of the animal organism, represented by molecular...

Enhancing the Protective Immune Response to Administration of a LIVP-GFP Live Attenuated Vaccinia Virus to Mice.

Pathogens (Basel, Switzerland)

Shchelkunov SN, Yakubitskiy SN, Titova KA, Pyankov SA, Sergeev AA.
PMID: 33801026
Pathogens. 2021 Mar 21;10(3). doi: 10.3390/pathogens10030377.

Following the WHO announcement of smallpox eradication, discontinuation of smallpox vaccination with vaccinia virus (VACV) was recommended. However, interest in VACV was soon renewed due to the opportunity of genetic engineering of the viral genome by directed insertion of...

Showing 13 to 24 of 27 entries