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Showing 25 to 36 of 226 entries
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Some Reflections on IBM Watson and on Women's Health.

Clinical therapeutics

Shader RI.
PMID: 26773356
Clin Ther. 2016 Jan 01;38(1):1-2. doi: 10.1016/j.clinthera.2015.12.008.

No abstract available.

Trends in Pretreatment HIV-1 Drug Resistance in Antiretroviral Therapy-naive Adults in South Africa, 2000-2016: A Pooled Sequence Analysis.

EClinicalMedicine

Chimukangara B, Lessells RJ, Rhee SY, Giandhari J, Kharsany ABM, Naidoo K, Lewis L, Cawood C, Khanyile D, Ayalew KA, Diallo K, Samuel R, Hunt G, Vandormael A, Stray-Pedersen B, Gordon M, Makadzange T, Kiepiela P, Ramjee G, Ledwaba J, Kalimashe M, Morris L, Parikh UM, Mellors JW, Shafer RW, Katzenstein D, Moodley P, Gupta RK, Pillay D, Abdool Karim SS, de Oliveira T.
PMID: 31143879
EClinicalMedicine. 2019 Mar 18;9:26-34. doi: 10.1016/j.eclinm.2019.03.006. eCollection 2019 Mar.

BACKGROUND: South Africa has the largest public antiretroviral therapy (ART) programme in the world. We assessed temporal trends in pretreatment HIV-1 drug resistance (PDR) in ART-naĂŻve adults from South Africa.METHODS: We included datasets from studies conducted between 2000 and...

Can Beliefs Be Modified?.

Clinical therapeutics

Shader RI.
PMID: 31133335
Clin Ther. 2019 Jun;41(6):1005-1008. doi: 10.1016/j.clinthera.2019.05.004. Epub 2019 May 24.

No abstract available.

Differences in fatigability of muscles involved in fecal continence: Potential clinical ramifications.

Physiological reports

Patel K, Mei L, Yu E, Kern M, Lehal N, Edeani F, Sanvanson P, Davidson ERW, Shaker R.
PMID: 34927399
Physiol Rep. 2021 Dec;9(24):e15144. doi: 10.14814/phy2.15144.

INTRODUCTION: Fatigue of the anal sphincter complex has been demonstrated using high-resolution anorectal manometry (HRAM). However, the fatigability of individual muscles such as the external anal sphincter (EAS) and puborectalis muscles (PRM) has not been described. Vaginal manometry has...

Patch Testing to Carvone: North American Contact Dermatitis Group Experience, 2009 to 2018.

Dermatitis : contact, atopic, occupational, drug

Warshaw EM, Shaver RL, DeKoven JG, Maibach HI, Taylor JS, Atwater AR, Belsito DV, Silverberg JI, Reeder MJ, Zug KA, Sasseville D, Fowler JF, Pratt MD, Fransway AF, DeLeo VA.
PMID: 33867494
Dermatitis. 2022 Jan-Feb 01;33(1):42-50. doi: 10.1097/DER.0000000000000741.

BACKGROUND/OBJECTIVES: Carvone, a flavoring agent, may cause allergic contact dermatitis. This study summarizes patch test reactions to carvone in patients tested by the North American Contact Dermatitis Group, 2009 to 2018.METHODS: This was a retrospective analysis of patients positive...

Vancomycin therapeutic monitoring by measured trough concentration versus Bayesian-derived area under the curve in critically ill patients with cancer.

Pharmacology research & perspectives

AbuSara AK, Abdelrahman DH, Habash KI, Al-Shaer MH, Le J, Nazer LH.
PMID: 34990089
Pharmacol Res Perspect. 2022 Feb;10(1):e00912. doi: 10.1002/prp2.912.

The updated vancomycin guideline and recent studies suggested that trough concentrations may result in underestimation of the actual area under the curve (AUC), leading to excessive dosing and nephrotoxicity. With limited data available on critically ill cancer patients, this...

SARS-CoV-2 Variants and Their Relevant Mutational Profiles: Update Summer 2021.

Microbiology spectrum

Alkhatib M, Svicher V, Salpini R, Ambrosio FA, Bellocchi MC, Carioti L, Piermatteo L, Scutari R, Costa G, Artese A, Alcaro S, Shafer R, Ceccherini-Silberstein F.
PMID: 34787497
Microbiol Spectr. 2021 Dec 22;9(3):e0109621. doi: 10.1128/Spectrum.01096-21. Epub 2021 Nov 17.

Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic caused by it, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been undergoing a genetic diversification leading to the emergence of new variants. Nevertheless, a clear definition of the...

Atypical neural processing during the execution of complex sensorimotor behavior in autism.

Behavioural brain research

Shafer RL, Lewis MH, Newell KM, Bodfish JW.
PMID: 33933522
Behav Brain Res. 2021 Jul 09;409:113337. doi: 10.1016/j.bbr.2021.113337. Epub 2021 Apr 30.

Stereotyped behavior is rhythmic, repetitive movement that is essentially invariant in form. Stereotypy is common in several clinical disorders, such as autism spectrum disorders (ASD), where it is considered maladaptive. However, it also occurs early in typical development (TD)...

Comments on Chronic Fatigue Syndrome.

Clinical therapeutics

Shader RI.
PMID: 30926194
Clin Ther. 2019 Apr;41(4):605-607. doi: 10.1016/j.clinthera.2019.03.003. Epub 2019 Mar 27.

No abstract available.

Femtosecond time synchronization of optical clocks off of a flying quadcopter.

Nature communications

Bergeron H, Sinclair LC, Swann WC, Khader I, Cossel KC, Cermak M, DeschĂȘnes JD, Newbury NR.
PMID: 31000702
Nat Commun. 2019 Apr 18;10(1):1819. doi: 10.1038/s41467-019-09768-9.

Future optical clock networks will require free-space optical time-frequency transfer between flying clocks. However, simple one-way or standard two-way time transfer between flying clocks will completely break down because of the time-of-flight variations and Doppler shifts associated with the...

Identification and characterization of rostral ventromedial medulla neurons synaptically connected to the urinary bladder afferents in female rats with or without neonatal cystitis.

The Journal of comparative neurology

Talluri B, Hoelzel F, Medda BK, Terashvili M, Sanvanson P, Shaker R, Banerjee A, Sengupta JN, Banerjee B.
PMID: 34628661
J Comp Neurol. 2021 Oct 09; doi: 10.1002/cne.25260. Epub 2021 Oct 09.

The neurons in the rostral ventromedial medulla (RVM) play a major role in pain modulation. We have previously shown that early-life noxious bladder stimuli in rats resulted in an overall spinal GABAergic disinhibition and a long-lasting bladder/colon sensitization when...

Some Reflections on Sleep and its Treatment.

Clinical therapeutics

Shader RI.
PMID: 27793355
Clin Ther. 2016 Nov;38(11):2325-2328. doi: 10.1016/j.clinthera.2016.10.002. Epub 2016 Oct 25.

No abstract available.

Showing 25 to 36 of 226 entries