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Showing 13 to 24 of 141 entries
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The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease.

American journal of respiratory cell and molecular biology

Schiller HB, Montoro DT, Simon LM, Rawlins EL, Meyer KB, Strunz M, Vieira Braga FA, Timens W, Koppelman GH, Budinger GRS, Burgess JK, Waghray A, van den Berge M, Theis FJ, Regev A, Kaminski N, Rajagopal J, Teichmann SA, Misharin AV, Nawijn MC.
PMID: 30995076
Am J Respir Cell Mol Biol. 2019 Jul;61(1):31-41. doi: 10.1165/rcmb.2018-0416TR.

Lung disease accounts for every sixth death globally. Profiling the molecular state of all lung cell types in health and disease is currently revolutionizing the identification of disease mechanisms and will aid the design of novel diagnostic and personalized...

Adapting behavioral activation for perinatal depression and anxiety in response to the COVID-19 pandemic and racial injustice.

Journal of affective disorders

Singla DR, Hossain S, Ravitz P, Schiller CE, Andrejek N, Kim J, La Porte L, Meltzer-Brody SE, Silver R, Vigod SN, Jung JW, Dimidjian S.
PMID: 34875282
J Affect Disord. 2021 Dec 05;299:180-187. doi: 10.1016/j.jad.2021.12.006. Epub 2021 Dec 05.

BACKGROUND: We examined the implementation of a brief, behavioural activation (BA) model, via telemedicine, for perinatal populations during a confluence of significant global events in 2020. We conducted a rigorous qualitative study to identify relevant barriers and facilitators from...

IL-37 regulates allergic inflammation by counterbalancing pro-inflammatory IL-1 and IL-33.

Allergy

Schröder A, Lunding LP, Zissler UM, Vock C, Webering S, Ehlers JC, Orinska Z, Chaker A, Schmidt-Weber CB, Lang NJ, Schiller HB, Mall MA, Fehrenbach H, Dinarello CA, Wegmann M.
PMID: 34460953
Allergy. 2021 Aug 30; doi: 10.1111/all.15072. Epub 2021 Aug 30.

BACKGROUND: Children with asthma have impaired production of interleukin (IL) 37; in mice, IL-37 reduces hallmarks of experimental allergic asthma (EAA). However, it remains unclear how IL-37 exerts its inhibitory properties in asthma. This study aimed to identify the...

Adapting behavioral activation for perinatal depression and anxiety in response to the COVID-19 pandemic and racial injustice.

Journal of affective disorders

Singla DR, Hossain S, Ravitz P, Schiller CE, Andrejek N, Kim J, La Porte L, Meltzer-Brody SE, Silver R, Vigod SN, Jung JW, Dimidjian S.
PMID: 34875282
J Affect Disord. 2021 Dec 05;299:180-187. doi: 10.1016/j.jad.2021.12.006. Epub 2021 Dec 05.

BACKGROUND: We examined the implementation of a brief, behavioural activation (BA) model, via telemedicine, for perinatal populations during a confluence of significant global events in 2020. We conducted a rigorous qualitative study to identify relevant barriers and facilitators from...

Adapting behavioral activation for perinatal depression and anxiety in response to the COVID-19 pandemic and racial injustice.

Journal of affective disorders

Singla DR, Hossain S, Ravitz P, Schiller CE, Andrejek N, Kim J, La Porte L, Meltzer-Brody SE, Silver R, Vigod SN, Jung JW, Dimidjian S.
PMID: 34875282
J Affect Disord. 2021 Dec 04; doi: 10.1016/j.jad.2021.12.006. Epub 2021 Dec 04.

BACKGROUND: We examined the implementation of a behavioural activation (BA) model, via telemedicine, for perinatal populations during a confluence of significant global events in 2020. We conducted a rigorous qualitative study to identify relevant barriers and facilitators from the...

Adapting behavioral activation for perinatal depression and anxiety in response to the COVID-19 pandemic and racial injustice.

Journal of affective disorders

Singla DR, Hossain S, Ravitz P, Schiller CE, Andrejek N, Kim J, La Porte L, Meltzer-Brody SE, Silver R, Vigod SN, Jung JW, Dimidjian S.
PMID: 34875282
J Affect Disord. 2021 Dec 05;299:180-187. doi: 10.1016/j.jad.2021.12.006. Epub 2021 Dec 05.

BACKGROUND: We examined the implementation of a brief, behavioural activation (BA) model, via telemedicine, for perinatal populations during a confluence of significant global events in 2020. We conducted a rigorous qualitative study to identify relevant barriers and facilitators from...

Generation and diversification of recombinant monoclonal antibodies.

eLife

DeLuca KF, Mick JE, Ide AH, Lima WC, Sherman L, Schaller KL, Anderson SM, Zhao N, Stasevich TJ, Varma D, Nilsson J, DeLuca JG.
PMID: 34970967
Elife. 2021 Dec 31;10. doi: 10.7554/eLife.72093. Epub 2021 Dec 31.

Antibodies are indispensable tools used for a large number of applications in both foundational and translational bioscience research; however, there are drawbacks to using traditional antibodies generated in animals. These include a lack of standardization leading to problems with...

Adapting behavioral activation for perinatal depression and anxiety in response to the COVID-19 pandemic and racial injustice.

Journal of affective disorders

Singla DR, Hossain S, Ravitz P, Schiller CE, Andrejek N, Kim J, La Porte L, Meltzer-Brody SE, Silver R, Vigod SN, Jung JW, Dimidjian S.
PMID: 34875282
J Affect Disord. 2021 Dec 05;299:180-187. doi: 10.1016/j.jad.2021.12.006. Epub 2021 Dec 05.

BACKGROUND: We examined the implementation of a brief, behavioural activation (BA) model, via telemedicine, for perinatal populations during a confluence of significant global events in 2020. We conducted a rigorous qualitative study to identify relevant barriers and facilitators from...

Composition, Stratigraphy, and Geological History of the Noachian Basement Surrounding the Isidis Impact Basin.

Journal of geophysical research. Planets

Scheller EL, Ehlmann BL.
PMID: 34422533
J Geophys Res Planets. 2020 Jul;125(7):e2019JE006190. doi: 10.1029/2019je006190. Epub 2020 Mar 10.

The western part of the Isidis basin structure hosts a well-characterized Early Noachian to Amazonian stratigraphy. The Noachian Basement comprises its oldest exposed rocks (Early to Mid-Noachian) and was previously considered a single low-Ca pyroxenes (LCP)- and Fe/Mg-smectite-bearing unit....

Association between fluoroquinolone utilization rates and susceptibilities of gram-negative bacilli: Results from an 8-year intervention by an antibiotic stewardship program in an inner-city United States hospital.

Science progress

Zeana C, Palmieri FE, Gupta V, Ye G, Lao P, Yu K, Kang KS, Schiller L, Purswani M.
PMID: 33908291
Sci Prog. 2021 Apr-Jun;104(2):368504211011876. doi: 10.1177/00368504211011876.

This study evaluated an antibiotic stewardship program (ASP) intervention aimed at reducing inpatient fluoroquinolone (FQ) use and examined its impact on ciprofloxacin susceptibilities of gram-negative bacteria in a large 611-bed community hospital. A two-step ASP intervention was implemented: an...

A Phase Ib Study of Onvansertib, a Novel Oral PLK1 Inhibitor, in Combination Therapy for Patients with Relapsed or Refractory Acute Myeloid Leukemia.

Clinical cancer research : an official journal of the American Association for Cancer Research

Zeidan AM, Ridinger M, Lin TL, Becker PS, Schiller GJ, Patel PA, Spira AI, Tsai ML, Samuëlsz E, Silberman SL, Erlander M, Wang ES.
PMID: 32998961
Clin Cancer Res. 2020 Dec 01;26(23):6132-6140. doi: 10.1158/1078-0432.CCR-20-2586. Epub 2020 Sep 30.

PURPOSE: The Polo-like kinase 1 (PLK1) is a master regulator of mitosis and overexpressed in acute myeloid leukemia (AML). We conducted a phase Ib study of the PLK1 inhibitor, onvansertib, in combination with either low-dose cytarabine (LDAC) or decitabine...

Adapting behavioral activation for perinatal depression and anxiety in response to the COVID-19 pandemic and racial injustice.

Journal of affective disorders

Singla DR, Hossain S, Ravitz P, Schiller CE, Andrejek N, Kim J, La Porte L, Meltzer-Brody SE, Silver R, Vigod SN, Jung JW, Dimidjian S.
PMID: 34875282
J Affect Disord. 2021 Dec 05;299:180-187. doi: 10.1016/j.jad.2021.12.006. Epub 2021 Dec 05.

BACKGROUND: We examined the implementation of a brief, behavioural activation (BA) model, via telemedicine, for perinatal populations during a confluence of significant global events in 2020. We conducted a rigorous qualitative study to identify relevant barriers and facilitators from...

Showing 13 to 24 of 141 entries