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Showing 25 to 36 of 248 entries
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The involvement of sodium in the function of the human amino acid transporter ASCT2.

FEBS letters

Mazza T, Scalise M, Pappacoda G, Pochini L, Indiveri C.
PMID: 34741534
FEBS Lett. 2021 Nov 06; doi: 10.1002/1873-3468.14224. Epub 2021 Nov 06.

Alanine, serine, cysteine transporter 2 (ASCT2) is a membrane amino acid transporter with relevance to human physiology and pathology, such as cancer. Notwithstanding, the study on the ASCT2 transport cycle still has unknown aspects, such as the role of...

Sequential modulation of the Wnt/β-catenin signaling pathway enhances tumor-intrinsic MHC I expression and tumor clearance.

Gynecologic oncology

Dholakia J, Scalise CB, Katre AA, Goldsberry WN, Meza-Perez S, Randall TD, Norian LA, Novak L, Arend RC.
PMID: 34844776
Gynecol Oncol. 2022 Jan;164(1):170-180. doi: 10.1016/j.ygyno.2021.09.026. Epub 2021 Nov 26.

BACKGROUND: Progress in immunotherapy use for gynecologic malignancies is hampered by poor tumor antigenicity and weak T cell infiltration of the tumor microenvironment (TME). Wnt/β-catenin pathway modulation demonstrated patient benefit in clinical trials as well as enhanced immune cell...

New silver(I) phosphino complexes: Evaluation of their potential as prospective agents against Mycobacterium tuberculosis.

Journal of inorganic biochemistry

Maldonado YD, Scalese G, Manieri KF, Pavan FR, Aguirre Méndez LD, Gambino D.
PMID: 34896768
J Inorg Biochem. 2021 Dec 03;227:111683. doi: 10.1016/j.jinorgbio.2021.111683. Epub 2021 Dec 03.

Despite being a preventable and curable disease, Tuberculosis (TB) is the world's top infectious killer. Development of new drugs is urgently needed. In this work, the synthesis and characterization of new silver(I) complexes, that include N'-[(E)-(pyridine-2-ylmethylene)pyrazine-2-carbohydrazide, HPCPH, as main...

Reconstruction of Full-thickness Soft Tissue Defects with Integra: Risk Factors and Treatment Algorithm.

Plastic and reconstructive surgery. Global open

Scalise A, Torresetti M, Di Benedetto G.
PMID: 33133950
Plast Reconstr Surg Glob Open. 2020 Sep 24;8(9):e3099. doi: 10.1097/GOX.0000000000003099. eCollection 2020 Sep.

BACKGROUND: Despite the fact that dermal substitutes are widely used in reconstructive surgery, there have been no studies focused on predictors of complications or delayed matrix take. We propose an algorithm for management of soft tissue reconstruction with Integra...

Comparison Between Invasive and Noninvasive Methods to Estimate Subendocardial Oxygen Supply and Demand Imbalance.

Journal of the American Heart Association

Salvi P, Baldi C, Scalise F, Grillo A, Salvi L, Tan I, De Censi L, Sorropago A, Moretti F, Sorropago G, Gao L, Rovina M, Simon G, Fabris B, Carretta R, Avolio AP, Parati G.
PMID: 34465133
J Am Heart Assoc. 2021 Sep 07;10(17):e021207. doi: 10.1161/JAHA.121.021207. Epub 2021 Sep 01.

Background Estimation of the balance between subendocardial oxygen supply and demand could be a useful parameter to assess the risk of myocardial ischemia. Evaluation of the subendocardial viability ratio (SEVR, also known as Buckberg index) by invasive recording of...

Unprotected left-main coronary percutaneous intervention in elderly: a retrospective analysis of practice and clinical outcome.

Journal of cardiovascular medicine (Hagerstown, Md.)

Scalone G, Mariani L, Di Vito L, Silenzi S, Grossi P.
PMID: 33136805
J Cardiovasc Med (Hagerstown). 2021 May 01;22(5):420-422. doi: 10.2459/JCM.0000000000001122.

No abstract available.

Rare and novel RUNX1 fusions in myeloid neoplasms: A single-institute experience.

Genes, chromosomes & cancer

Aypar U, Yao J, Londono DM, Khoobyar R, Scalise A, Arcila ME, Roshal M, Xiao W, Zhang Y.
PMID: 33078873
Genes Chromosomes Cancer. 2021 Feb;60(2):100-107. doi: 10.1002/gcc.22901. Epub 2020 Oct 21.

Chromosome translocations involving the RUNX1 gene at 21q22 are recurring abnormalities in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), that is, t(8;21) and t(3;21) and in B-cell acute lymphoblastic leukemia with t(12;21). These translocations result in the fusion...

A case report of metastatic giant sarcomatoid melanoma with BRAF V600E mutation: a complete response to targeted therapy.

Oncotarget

Torresetti M, Brancorsini D, Morgese F, Cognigni V, Scalise A, Berardi R, Di Benedetto G.
PMID: 32922664
Oncotarget. 2020 Aug 25;11(34):3256-3262. doi: 10.18632/oncotarget.27701. eCollection 2020 Aug 25.

Sarcomatoid melanoma is an extremely rare pattern of malignant melanoma, and only few cases have been described throughout the literature. We herein report a case of a patient with newly diagnosed, metastatic giant sarcomatoid melanoma of the arm. The...

Role of Internal Jugular Vein Ultrasound Measurements in the Assessment of Central Venous Pressure in Spontaneously Breathing Patients: A Systematic Review.

Journal of acute medicine

Parenti N, Scalese M, Palazzi C, Agrusta F, Cahill J, Agnelli G.
PMID: 32995230
J Acute Med. 2019 Jun 01;9(2):39-48. doi: 10.6705/j.jacme.201906_9(2).0001.

BACKGROUND: Few studies have tested the role of the internal jugular vein (IJV) ultrasonographic (US) diameters in the assessment of central venous pressure (CVP) in spontaneously breathing patients. No review or meta-analysis is currently available on the role of...

Prevalence and description of dental disorders in skulls of free-living wild primates from Paraná State, Brazil.

Journal of medical primatology

Przydzimirski AC, Correia AM, Scalise VP, Martini R, Maciel JVB, Lange RR.
PMID: 34738242
J Med Primatol. 2021 Nov 04; doi: 10.1111/jmp.12548. Epub 2021 Nov 04.

BACKGROUND: Non-human primates can present oral diseases. However, differences among the dentition of the various species make it difficult to understand their dental features and associated diseases. This research hypothesizes that the prevalence of dental disorders varies in the...

What COVID-19 taught us: New opportunities and pathways from telemedicine and novel antiseptics in wound healing.

International wound journal

Scalise A, Falcone M, Avruscio G, Brocco E, Ciacco E, Parodi A, Tasinato R, Ricci E.
PMID: 34599861
Int Wound J. 2021 Oct 02; doi: 10.1111/iwj.13695. Epub 2021 Oct 02.

The COVID-19 pandemic deeply impacted the capacity of the health systems to maintain preventive and curative services, especially for the most vulnerable populations. During the pandemic, the wound healing centres in Italy assisted a significant reduction of the frequency...

Prismatic Ge-rich inclusions in the hexagonal SiGe shell of GaP-Si-SiGe nanowires by controlled faceting.

Nanoscale

Bergamaschini R, Plantenga RC, Albani M, Scalise E, Ren Y, Hauge HIT, Kölling S, Montalenti F, Bakkers EPAM, Verheijen MA, Miglio L.
PMID: 34008608
Nanoscale. 2021 May 27;13(20):9436-9445. doi: 10.1039/d0nr08051a.

Formation of Ge-rich prismatic inclusions in the hexagonal SiGe shell of GaP-Si-SiGe nanowires is reported and discussed in relation to a growth model that explains their origin. An accurate TEM/EDX analysis shows that such prisms develop right on top...

Showing 25 to 36 of 248 entries