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Showing 25 to 36 of 256 entries
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The Prognostic Value of Low Muscle Mass in Pancreatic Cancer Patients: A Systematic Review and Meta-Analysis.

Journal of clinical medicine

Pierobon ES, Moletta L, Zampieri S, Sartori R, Brazzale AR, Zanchettin G, Serafini S, Capovilla G, Valmasoni M, Merigliano S, Sperti C.
PMID: 34300199
J Clin Med. 2021 Jul 07;10(14). doi: 10.3390/jcm10143033.

Low muscle mass is associated with reduced survival in patients with different cancer types. The interest in preoperative sarcopenia and pancreatic cancer has risen in the last decade as muscle mass loss seems to be associated with poorer survival,...

Reinstatement of synaptic plasticity in the aging brain through specific dopamine transporter inhibition.

Molecular psychiatry

Lubec J, Kalaba P, Hussein AM, Feyissa DD, Kotob MH, Mahmmoud RR, Wieder O, Garon A, Sagheddu C, Ilic M, Dragačević V, Cybulska-Klosowicz A, Zehl M, Wackerlig J, Sartori SB, Ebner K, Kouhnavardi S, Roller A, Gajic N, Pistis M, Singewald N, Leban JJ, Korz V, Malikovic J, Plasenzotti R, Sitte HH, Monje FJ, Langer T, Urban E, Pifl C, Lubec G.
PMID: 34244620
Mol Psychiatry. 2021 Jul 09; doi: 10.1038/s41380-021-01214-x. Epub 2021 Jul 09.

Aging-related neurological deficits negatively impact mental health, productivity, and social interactions leading to a pronounced socioeconomic burden. Since declining brain dopamine signaling during aging is associated with the onset of neurological impairments, we produced a selective dopamine transporter (DAT)...

Rituximab and Bendamustine (BR) Compared with Rituximab, Bendamustine, and Cytarabine (R-BAC) in Previously Untreated Elderly Patients with Mantle Cell Lymphoma.

Cancers

Bega G, Olivieri J, Riva M, Scapinello G, Paolini R, Finotto S, Sartori R, Lucchini E, Guandalini G, Facchinelli D, Tisi MC, Basso M, Ballotta L, Piazza F, Ferrarini I, Visco C.
PMID: 34885198
Cancers (Basel). 2021 Dec 03;13(23). doi: 10.3390/cancers13236089.

BACKGROUND: Rituximab plus bendamustine (BR), and rituximab, bendamustine, and cytarabine (R-BAC) are well-known induction therapies in elderly patients with mantle cell lymphoma (MCL), according to clinical guidelines. However, a direct comparison between the two regimens has never been performed.METHODS:...

Reproduction, Skin Aging and Sleep in Middle-Aged Women.

Clinics in dermatology

Xerfan EMS, Sartor A, Samama M, Facina AS, Tomimori J, Andersen ML.
PMID: 34780897
Clin Dermatol. 2021 Nov 12; doi: 10.1016/j.clindermatol.2021.11.001. Epub 2021 Nov 12.

There is a growing trend for women to delay having children, with a significant number of women postponing motherhood until the third or fourth decade of life. At the same time, these middle-aged women may be more concerned about...

Short- and long-term effects of perinatal phthalate exposures on metabolic pathways in the mouse liver.

Environmental epigenetics

Neier K, Montrose L, Chen K, Malloy MA, Jones TR, Svoboda LK, Harris C, Song PXK, Pennathur S, Sartor MA, Dolinoy DC.
PMID: 33391822
Environ Epigenet. 2020 Dec 23;6(1):dvaa017. doi: 10.1093/eep/dvaa017. eCollection 2020.

Phthalates have been demonstrated to interfere with metabolism, presumably by interacting with peroxisome proliferator-activated receptors (PPARs). However, mechanisms linking developmental phthalate exposures to long-term metabolic effects have not yet been elucidated. We investigated the hypothesis that developmental phthalate exposure...

Targeting Adaptive Immune Responses to Human Bacterial Flagellins in Crohn's Disease.

Gastroenterology

Sartor RB.
PMID: 34015336
Gastroenterology. 2021 Aug;161(2):416-418. doi: 10.1053/j.gastro.2021.05.031. Epub 2021 May 18.

No abstract available.

Evidence-based intervention program for reducing obesity among African-American women in Southern California.

Public health nursing (Boston, Mass.)

Onyegbule P, Iyiegbuniwe E, Sarter B, James KS.
PMID: 33496008
Public Health Nurs. 2021 May;38(3):350-356. doi: 10.1111/phn.12830. Epub 2021 Jan 26.

OBJECTIVE: This study evaluated the effectiveness of group motivational education and empowerment program using evidence-based approaches for obesity and weight loss management for African-American Women.DESIGN: This study employed a quasi-experimental time series design based on the theoretical frameworks of...

Molecular Tumor Subtypes of HPV-Positive Head and Neck Cancers: Biological Characteristics and Implications for Clinical Outcomes.

Cancers

Qin T, Li S, Henry LE, Liu S, Sartor MA.
PMID: 34072836
Cancers (Basel). 2021 May 31;13(11). doi: 10.3390/cancers13112721.

Until recently, research on the molecular signatures of Human papillomavirus (HPV)-associated head and neck cancers mainly focused on their differences with respect to HPV-negative head and neck squamous cell carcinomas (HNSCCs). However, given the continuing high incidence level of...

Neuroinvasive West Nile Infection with an Unusual Clinical Presentation: A Single-Center Case Series.

Tropical medicine and infectious disease

Castaldo N, Graziano E, Peghin M, Gallo T, D'Agaro P, Sartor A, Bove T, Cocconi R, Merlino G, Bassetti M.
PMID: 32878269
Trop Med Infect Dis. 2020 Aug 31;5(3). doi: 10.3390/tropicalmed5030138.

The 2018 West Nile Virus (WNV) season in Europe was characterized by an extremely high infection rate and an exceptionally higher burden when compared to previous seasons. Overall, there was a 10.9-fold increase in incidence in Italy, with 577...

Post-traumatic entrapment of the median nerve in the ulno-humeral joint: Diagnosis, treatment and literature review.

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association

Montanari S, Sartore R, Spina V, Adani R.
PMID: 33863636
J Orthop Sci. 2021 Apr 14; doi: 10.1016/j.jos.2021.02.006. Epub 2021 Apr 14.

BACKGROUND: The incidence of median nerve injuries in pediatric elbow dislocations is approximately 3% and avulsion of the open medial epicondylar epiphysis in the pediatric population is one predisposing factor that may explain this age predilection. These lesions can...

Microfluidic Formulation of DNA-Loaded Multicomponent Lipid Nanoparticles for Gene Delivery.

Pharmaceutics

Quagliarini E, Renzi S, Digiacomo L, Giulimondi F, Sartori B, Amenitsch H, Tassinari V, Masuelli L, Bei R, Cui L, Wang J, Amici A, Marchini C, Pozzi D, Caracciolo G.
PMID: 34452253
Pharmaceutics. 2021 Aug 19;13(8). doi: 10.3390/pharmaceutics13081292.

In recent years, lipid nanoparticles (LNPs) have gained considerable attention in numerous research fields ranging from gene therapy to cancer immunotherapy and DNA vaccination. While some RNA-encapsulating LNP formulations passed clinical trials, DNA-loaded LNPs have been only marginally explored...

Assessment of Magnetic Resonance Imaging Changes and Functional Outcomes Among Adults With Severe Herpes Simplex Encephalitis.

JAMA network open

Sarton B, Jaquet P, Belkacemi D, de Montmollin E, Bonneville F, Sazio C, Frérou A, Conrad M, Daubin D, Chabanne R, Argaud L, Dailler F, Brulé N, Lerolle N, Maestraggi Q, Marechal J, Bailly P, Razazi K, Mateos F, Guidet B, Levrat A, Susset V, Lautrette A, Mira JP, El Kalioubie A, Robert A, Massri A, Albucher JF, Olivot JM, Conil JM, Boudma L, Timsit JF, Sonneville R, Silva S.
PMID: 34313743
JAMA Netw Open. 2021 Jul 01;4(7):e2114328. doi: 10.1001/jamanetworkopen.2021.14328.

IMPORTANCE: Current guidelines recommend brain magnetic resonance imaging (MRI) for clinical management of patients with severe herpes simplex encephalitis (HSE). However, the prognostic value of brain imaging has not been demonstrated in this setting.OBJECTIVE: To investigate the association between...

Showing 25 to 36 of 256 entries