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MDM4 expression as an indicator of TP53 reactivation by combined targeting of MDM2 and MDM4 in cancer cells without TP53 mutation.

Oncoscience

Hirose M, Yamato K, Endo S, Saito R, Ueno T, Hirai S, Suzuki H, Abei M, Natori Y, Hyodo I.
PMID: 25621298
Oncoscience. 2014 Nov 25;1(12):830-43. doi: 10.18632/oncoscience.103. eCollection 2014.

MDM2 and MDM4, a structurally related MDM2 homolog, negatively regulates expression and functions of TP53 tumor suppressor gene. To explore the precise expression patterns and function of MDM2 and MDM4 in wild-type (wt) TP53 cancer cells, we analyzed 11...

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Hirose M, Yamato K, Endo S, et al. MDM4 expression as an indicator of TP53 reactivation by combined targeting of MDM2 and MDM4 in cancer cells without TP53 mutation. Oncoscience. 2014;1(12):830-43doi: 10.18632/oncoscience.103.
Hirose, M., Yamato, K., Endo, S., Saito, R., Ueno, T., Hirai, S., Suzuki, H., Abei, M., Natori, Y., & Hyodo, I. (2014). MDM4 expression as an indicator of TP53 reactivation by combined targeting of MDM2 and MDM4 in cancer cells without TP53 mutation. Oncoscience, 1(12), 830-43. https://doi.org/10.18632/oncoscience.103
Hirose, Mitsuaki, et al. "MDM4 expression as an indicator of TP53 reactivation by combined targeting of MDM2 and MDM4 in cancer cells without TP53 mutation." Oncoscience vol. 1,12 (2014): 830-43. doi: https://doi.org/10.18632/oncoscience.103
Hirose M, Yamato K, Endo S, Saito R, Ueno T, Hirai S, Suzuki H, Abei M, Natori Y, Hyodo I. MDM4 expression as an indicator of TP53 reactivation by combined targeting of MDM2 and MDM4 in cancer cells without TP53 mutation. Oncoscience. 2014 Nov 25;1(12):830-43. doi: 10.18632/oncoscience.103. eCollection 2014. PMID: 25621298; PMCID: PMC4303891.
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Chronic inflammation in urothelial bladder cancer.

Virchows Archiv : an international journal of pathology

Nesi G, Nobili S, Cai T, Caini S, Santi R.
PMID: 26263854
Virchows Arch. 2015 Dec;467(6):623-633. doi: 10.1007/s00428-015-1820-x. Epub 2015 Aug 12.

The association between inflammation and cancer has been pointed out in epidemiological and clinical studies, revealing how chronic inflammation may contribute to carcinogenesis in various malignancies. However, the molecular events leading to malignant transformation in a chronically inflamed environment...

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Nesi G, Nobili S, Cai T, et al. Chronic inflammation in urothelial bladder cancer. Virchows Arch. 2015;467(6):623-633doi: 10.1007/s00428-015-1820-x.
Nesi, G., Nobili, S., Cai, T., Caini, S., & Santi, R. (2015). Chronic inflammation in urothelial bladder cancer. Virchows Archiv : an international journal of pathology, 467(6), 623-633. https://doi.org/10.1007/s00428-015-1820-x
Nesi, Gabriella, et al. "Chronic inflammation in urothelial bladder cancer." Virchows Archiv : an international journal of pathology vol. 467,6 (2015): 623-633. doi: https://doi.org/10.1007/s00428-015-1820-x
Nesi G, Nobili S, Cai T, Caini S, Santi R. Chronic inflammation in urothelial bladder cancer. Virchows Arch. 2015 Dec;467(6):623-633. doi: 10.1007/s00428-015-1820-x. Epub 2015 Aug 12. PMID: 26263854.
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Membranous nephropathy associated with primary biliary cirrhosis and acute meningitis.

Clinical journal of gastroenterology

Sato S, Saito R, Iwadate H, Asano T, Abe K, Takahashi A, Kobayashi H, Watanabe H, Ohira H.
PMID: 26182396
Clin J Gastroenterol. 2012 Aug;5(4):292-7. doi: 10.1007/s12328-012-0321-6. Epub 2012 Jul 20.

A 40-year-old man with acute meningitis, nephrotic syndrome, elevated antinuclear antibody (2560×), and liver dysfunction was referred to our hospital. He was antimitochondrial antibody positive, and renal and liver biopsy findings revealed membranous nephropathy (MN) and primary biliary cirrhosis...

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Sato S, Saito R, Iwadate H, et al. Membranous nephropathy associated with primary biliary cirrhosis and acute meningitis. Clin J Gastroenterol. 2012;5(4):292-7doi: 10.1007/s12328-012-0321-6.
Sato, S., Saito, R., Iwadate, H., Asano, T., Abe, K., Takahashi, A., Kobayashi, H., Watanabe, H., & Ohira, H. (2012). Membranous nephropathy associated with primary biliary cirrhosis and acute meningitis. Clinical journal of gastroenterology, 5(4), 292-7. https://doi.org/10.1007/s12328-012-0321-6
Sato, Shuzo, et al. "Membranous nephropathy associated with primary biliary cirrhosis and acute meningitis." Clinical journal of gastroenterology vol. 5,4 (2012): 292-7. doi: https://doi.org/10.1007/s12328-012-0321-6
Sato S, Saito R, Iwadate H, Asano T, Abe K, Takahashi A, Kobayashi H, Watanabe H, Ohira H. Membranous nephropathy associated with primary biliary cirrhosis and acute meningitis. Clin J Gastroenterol. 2012 Aug;5(4):292-7. doi: 10.1007/s12328-012-0321-6. Epub 2012 Jul 20. PMID: 26182396.
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Prognostic impact of carbohydrate sulfotransferase 15 in patients with pancreatic ductal adenocarcinoma.

Oncology letters

Ito Z, Takakura K, Suka M, Kanai T, Saito R, Fujioka S, Kajihara M, Yanagisawa H, Misawa T, Akiba T, Koido S, Ohkusa T.
PMID: 28599481
Oncol Lett. 2017 Jun;13(6):4799-4805. doi: 10.3892/ol.2017.6071. Epub 2017 Apr 21.

Patients with pancreatic ductal adenocarcinoma (PDA) typically succumb to mortality early, even following surgical resection. Therefore, prognostic factors associated with early mortality are required to improve the survival of patients with PDA following surgical resection. Carbohydrate sulfotransferase 15 (CHST15)...

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Ito Z, Takakura K, Suka M, et al. Prognostic impact of carbohydrate sulfotransferase 15 in patients with pancreatic ductal adenocarcinoma. Oncol Lett. 2017;13(6):4799-4805doi: 10.3892/ol.2017.6071.
Ito, Z., Takakura, K., Suka, M., Kanai, T., Saito, R., Fujioka, S., Kajihara, M., Yanagisawa, H., Misawa, T., Akiba, T., Koido, S., & Ohkusa, T. (2017). Prognostic impact of carbohydrate sulfotransferase 15 in patients with pancreatic ductal adenocarcinoma. Oncology letters, 13(6), 4799-4805. https://doi.org/10.3892/ol.2017.6071
Ito, Zensho, et al. "Prognostic impact of carbohydrate sulfotransferase 15 in patients with pancreatic ductal adenocarcinoma." Oncology letters vol. 13,6 (2017): 4799-4805. doi: https://doi.org/10.3892/ol.2017.6071
Ito Z, Takakura K, Suka M, Kanai T, Saito R, Fujioka S, Kajihara M, Yanagisawa H, Misawa T, Akiba T, Koido S, Ohkusa T. Prognostic impact of carbohydrate sulfotransferase 15 in patients with pancreatic ductal adenocarcinoma. Oncol Lett. 2017 Jun;13(6):4799-4805. doi: 10.3892/ol.2017.6071. Epub 2017 Apr 21. PMID: 28599481; PMCID: PMC5453115.
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Selective coherent phonon-mode generation in single-wall carbon nanotubes.

Journal of physics. Condensed matter : an Institute of Physics journal

Nugraha AR, Hasdeo EH, Saito R.
PMID: 27941224
J Phys Condens Matter. 2017 Feb 08;29(5):055302. doi: 10.1088/1361-648X/29/5/055302. Epub 2016 Dec 12.

The pulse-train technique within ultrafast pump-probe spectroscopy is theoretically investigated to excite a specific coherent phonon mode while suppressing the other phonon modes generated in single-wall carbon nanotubes (SWNTs). In particular, we focus on the selectivity of the radial...

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Nugraha AR, Hasdeo EH, Saito R. Selective coherent phonon-mode generation in single-wall carbon nanotubes. J Phys Condens Matter. 2016;29(5):055302doi: 10.1088/1361-648X/29/5/055302.
Nugraha, A. R., Hasdeo, E. H., & Saito, R. (2017). Selective coherent phonon-mode generation in single-wall carbon nanotubes. Journal of physics. Condensed matter : an Institute of Physics journal, 29(5), 055302. https://doi.org/10.1088/1361-648X/29/5/055302
Nugraha, Ahmad R T, et al. "Selective coherent phonon-mode generation in single-wall carbon nanotubes." Journal of physics. Condensed matter : an Institute of Physics journal vol. 29,5 (2017): 055302. doi: https://doi.org/10.1088/1361-648X/29/5/055302
Nugraha AR, Hasdeo EH, Saito R. Selective coherent phonon-mode generation in single-wall carbon nanotubes. J Phys Condens Matter. 2017 Feb 08;29(5):055302. doi: 10.1088/1361-648X/29/5/055302. Epub 2016 Dec 12. PMID: 27941224.
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The binding structure and affinity of photodamaged duplex DNA with members of the photolyase/cryptochrome family: A computational study.

Biophysics and physicobiology

Sato R, Harada R, Shigeta Y.
PMID: 29450111
Biophys Physicobiol. 2018 Jan 20;15:18-27. doi: 10.2142/biophysico.15.0_18. eCollection 2018.

Photolyases (PHRs) and cryptochromes (CRYs) belong to the same family known as blue-light photoreceptors. Although their amino acid sequences and corresponding structures are similar to each other, they exert different functions. PHRs function as an enzyme to repair UV-induced...

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Sato R, Harada R, Shigeta Y. The binding structure and affinity of photodamaged duplex DNA with members of the photolyase/cryptochrome family: A computational study. Biophys Physicobiol. 2018;15:18-27doi: 10.2142/biophysico.15.0_18.
Sato, R., Harada, R., & Shigeta, Y. (2018). The binding structure and affinity of photodamaged duplex DNA with members of the photolyase/cryptochrome family: A computational study. Biophysics and physicobiology, 1518-27. https://doi.org/10.2142/biophysico.15.0_18
Sato, Ryuma, et al. "The binding structure and affinity of photodamaged duplex DNA with members of the photolyase/cryptochrome family: A computational study." Biophysics and physicobiology vol. 15 (2018): 18-27. doi: https://doi.org/10.2142/biophysico.15.0_18
Sato R, Harada R, Shigeta Y. The binding structure and affinity of photodamaged duplex DNA with members of the photolyase/cryptochrome family: A computational study. Biophys Physicobiol. 2018 Jan 20;15:18-27. doi: 10.2142/biophysico.15.0_18. eCollection 2018. PMID: 29450111; PMCID: PMC5812317.
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Determination of β-d-glucan and endotoxin levels in Kampo extracts.

Acute medicine & surgery

Nakae H, Takahashi G, Sato R, Shibata S, Endo S.
PMID: 29123698
Acute Med Surg. 2014 Oct 01;2(2):77-81. doi: 10.1002/ams2.70. eCollection 2015 Apr.

AIMS: Kampo medicine is based on the use of established formulations combining natural extracts with no "brand-name" products or corresponding "generic" formulation. Due to differences in manufacturing practices, products of different pharmaceutical companies may contain different concentrations of β-d-glucan...

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Nakae H, Takahashi G, Sato R, et al. Determination of β-d-glucan and endotoxin levels in Kampo extracts. Acute Med Surg. 2014;2(2):77-81doi: 10.1002/ams2.70.
Nakae, H., Takahashi, G., Sato, R., Shibata, S., & Endo, S. (2015). Determination of β-d-glucan and endotoxin levels in Kampo extracts. Acute medicine & surgery, 2(2), 77-81. https://doi.org/10.1002/ams2.70
Nakae, Hajime, et al. "Determination of β-d-glucan and endotoxin levels in Kampo extracts." Acute medicine & surgery vol. 2,2 (2015): 77-81. doi: https://doi.org/10.1002/ams2.70
Nakae H, Takahashi G, Sato R, Shibata S, Endo S. Determination of β-d-glucan and endotoxin levels in Kampo extracts. Acute Med Surg. 2014 Oct 01;2(2):77-81. doi: 10.1002/ams2.70. eCollection 2015 Apr. PMID: 29123698; PMCID: PMC5667204.
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Using administrative data to study child health.

Healthcare policy = Politiques de sante

Brownell M, Kozyrskyj A, Fuchs D, Santos R.
PMID: 24933380
Healthc Policy. 2011 Jan;6:91-3.

No abstract available.

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Brownell M, Kozyrskyj A, Fuchs D, et al. Utilisation des données administratives pour étudier l'état de santé des enfants. Using administrative data to study child health. Healthc Policy. 2011;6:91-3
Brownell, M., Kozyrskyj, A., Fuchs, D., & Santos, R. (2011). Utilisation des données administratives pour étudier l'état de santé des enfants. Using administrative data to study child health. Healthcare policy = Politiques de sante, 691-3.
Brownell, Marni, et al. "Utilisation des données administratives pour étudier l'état de santé des enfants." Using administrative data to study child health. Healthcare policy = Politiques de sante vol. 6 (2011): 91-3.
Brownell M, Kozyrskyj A, Fuchs D, Santos R. Utilisation des données administratives pour étudier l'état de santé des enfants. Using administrative data to study child health. Healthc Policy. 2011 Jan;6:91-3. PMID: 24933380; PMCID: PMC5319580.
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Nanoscale layer-selective readout of magnetization direction from a magnetic multilayer using a spin-torque oscillator.

Nanotechnology

Suto H, Nagasawa T, Kudo K, Mizushima K, Sato R.
PMID: 24872254
Nanotechnology. 2014 Jun 20;25(24):245501. doi: 10.1088/0957-4484/25/24/245501.

Technology for detecting the magnetization direction of nanoscale magnetic material is crucial for realizing high-density magnetic recording devices. Conventionally, a magnetoresistive device is used that changes its resistivity in accordance with the direction of the stray field from an...

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Suto H, Nagasawa T, Kudo K, et al. Nanoscale layer-selective readout of magnetization direction from a magnetic multilayer using a spin-torque oscillator. Nanotechnology. 2014;25(24):245501doi: 10.1088/0957-4484/25/24/245501.
Suto, H., Nagasawa, T., Kudo, K., Mizushima, K., & Sato, R. (2014). Nanoscale layer-selective readout of magnetization direction from a magnetic multilayer using a spin-torque oscillator. Nanotechnology, 25(24), 245501. https://doi.org/10.1088/0957-4484/25/24/245501
Suto, Hirofumi, et al. "Nanoscale layer-selective readout of magnetization direction from a magnetic multilayer using a spin-torque oscillator." Nanotechnology vol. 25,24 (2014): 245501. doi: https://doi.org/10.1088/0957-4484/25/24/245501
Suto H, Nagasawa T, Kudo K, Mizushima K, Sato R. Nanoscale layer-selective readout of magnetization direction from a magnetic multilayer using a spin-torque oscillator. Nanotechnology. 2014 Jun 20;25(24):245501. doi: 10.1088/0957-4484/25/24/245501. PMID: 24872254.
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Surrogate endpoints for overall survival in advanced non-small-cell lung cancer patients with mutations of the epidermal growth factor receptor gene.

Molecular and clinical oncology

Yoshino R, Imai H, Mori K, Takei K, Tomizawa M, Kaira K, Yoshii A, Tomizawa Y, Saito R, Yamada M.
PMID: 25054038
Mol Clin Oncol. 2014 Sep;2(5):731-736. doi: 10.3892/mco.2014.334. Epub 2014 Jul 01.

Subsequent therapies confound the ability to discern the effect of first-line chemotherapy on overall survival (OS). We investigated whether progression-free survival (PFS), post-progression survival (PPS) and tumor response were valid surrogate endpoints for OS following first-line chemotherapy in individual...

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Yoshino R, Imai H, Mori K, et al. Surrogate endpoints for overall survival in advanced non-small-cell lung cancer patients with mutations of the epidermal growth factor receptor gene. Mol Clin Oncol. 2014;2(5):731-736doi: 10.3892/mco.2014.334.
Yoshino, R., Imai, H., Mori, K., Takei, K., Tomizawa, M., Kaira, K., Yoshii, A., Tomizawa, Y., Saito, R., & Yamada, M. (2014). Surrogate endpoints for overall survival in advanced non-small-cell lung cancer patients with mutations of the epidermal growth factor receptor gene. Molecular and clinical oncology, 2(5), 731-736. https://doi.org/10.3892/mco.2014.334
Yoshino, Reiko, et al. "Surrogate endpoints for overall survival in advanced non-small-cell lung cancer patients with mutations of the epidermal growth factor receptor gene." Molecular and clinical oncology vol. 2,5 (2014): 731-736. doi: https://doi.org/10.3892/mco.2014.334
Yoshino R, Imai H, Mori K, Takei K, Tomizawa M, Kaira K, Yoshii A, Tomizawa Y, Saito R, Yamada M. Surrogate endpoints for overall survival in advanced non-small-cell lung cancer patients with mutations of the epidermal growth factor receptor gene. Mol Clin Oncol. 2014 Sep;2(5):731-736. doi: 10.3892/mco.2014.334. Epub 2014 Jul 01. PMID: 25054038; PMCID: PMC4106738.
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CARBON/NUTRIENT BALANCE IN RELATION TO BIOMASS PRODUCTION AND HALOGENATED COMPOUND CONTENT IN THE RED ALGA ASPARAGOPSIS TAXIFORMIS (BONNEMAISONIACEAE)(1).

Journal of phycology

Mata L, Gaspar H, Santos R.
PMID: 27009670
J Phycol. 2012 Feb;48(1):248-53. doi: 10.1111/j.1529-8817.2011.01083.x. Epub 2011 Dec 12.

We tested how the availability of carbon and nitrogen determines both the production of Asparagopsis taxiformis (Delile) V. Trevis. and content of the two major halocarbons, bromoform and dibromoacetic acid. The halogenated secondary metabolites of Asparagopsis species are particularly...

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Mata L, Gaspar H, Santos R. CARBON/NUTRIENT BALANCE IN RELATION TO BIOMASS PRODUCTION AND HALOGENATED COMPOUND CONTENT IN THE RED ALGA ASPARAGOPSIS TAXIFORMIS (BONNEMAISONIACEAE)(1). J Phycol. 2011;48(1):248-53doi: 10.1111/j.1529-8817.2011.01083.x.
Mata, L., Gaspar, H., & Santos, R. (2012). CARBON/NUTRIENT BALANCE IN RELATION TO BIOMASS PRODUCTION AND HALOGENATED COMPOUND CONTENT IN THE RED ALGA ASPARAGOPSIS TAXIFORMIS (BONNEMAISONIACEAE)(1). Journal of phycology, 48(1), 248-53. https://doi.org/10.1111/j.1529-8817.2011.01083.x
Mata, Leonardo, et al. "CARBON/NUTRIENT BALANCE IN RELATION TO BIOMASS PRODUCTION AND HALOGENATED COMPOUND CONTENT IN THE RED ALGA ASPARAGOPSIS TAXIFORMIS (BONNEMAISONIACEAE)(1)." Journal of phycology vol. 48,1 (2012): 248-53. doi: https://doi.org/10.1111/j.1529-8817.2011.01083.x
Mata L, Gaspar H, Santos R. CARBON/NUTRIENT BALANCE IN RELATION TO BIOMASS PRODUCTION AND HALOGENATED COMPOUND CONTENT IN THE RED ALGA ASPARAGOPSIS TAXIFORMIS (BONNEMAISONIACEAE)(1). J Phycol. 2012 Feb;48(1):248-53. doi: 10.1111/j.1529-8817.2011.01083.x. Epub 2011 Dec 12. PMID: 27009670.
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Conversion of leucine to β-hydroxy-β-methylbutyrate by α-keto isocaproate dioxygenase is required for a potent stimulation of protein synthesis in L6 rat myotubes.

Journal of cachexia, sarcopenia and muscle

Girón MD, Vílchez JD, Salto R, Manzano M, Sevillano N, Campos N, Argilés JM, Rueda R, López-Pedrosa JM.
PMID: 27065075
J Cachexia Sarcopenia Muscle. 2016 Mar;7(1):68-78. doi: 10.1002/jcsm.12032. Epub 2015 May 14.

BACKGROUND: L-Leu and its metabolite β-hydroxy-β-methylbutyrate (HMB) stimulate muscle protein synthesis enhancing the phosphorylation of proteins that regulate anabolic signalling pathways. Alterations in these pathways are observed in many catabolic diseases, and HMB and L-Leu have proven their anabolic...

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Girón MD, Vílchez JD, Salto R, et al. Conversion of leucine to β-hydroxy-β-methylbutyrate by α-keto isocaproate dioxygenase is required for a potent stimulation of protein synthesis in L6 rat myotubes. J Cachexia Sarcopenia Muscle. 2015;7(1):68-78doi: 10.1002/jcsm.12032.
Girón, M. D., Vílchez, J. D., Salto, R., Manzano, M., Sevillano, N., Campos, N., Argilés, J. M., Rueda, R., & López-Pedrosa, J. M. (2016). Conversion of leucine to β-hydroxy-β-methylbutyrate by α-keto isocaproate dioxygenase is required for a potent stimulation of protein synthesis in L6 rat myotubes. Journal of cachexia, sarcopenia and muscle, 7(1), 68-78. https://doi.org/10.1002/jcsm.12032
Girón, María D, et al. "Conversion of leucine to β-hydroxy-β-methylbutyrate by α-keto isocaproate dioxygenase is required for a potent stimulation of protein synthesis in L6 rat myotubes." Journal of cachexia, sarcopenia and muscle vol. 7,1 (2016): 68-78. doi: https://doi.org/10.1002/jcsm.12032
Girón MD, Vílchez JD, Salto R, Manzano M, Sevillano N, Campos N, Argilés JM, Rueda R, López-Pedrosa JM. Conversion of leucine to β-hydroxy-β-methylbutyrate by α-keto isocaproate dioxygenase is required for a potent stimulation of protein synthesis in L6 rat myotubes. J Cachexia Sarcopenia Muscle. 2016 Mar;7(1):68-78. doi: 10.1002/jcsm.12032. Epub 2015 May 14. PMID: 27065075; PMCID: PMC4799859.
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Showing 13 to 24 of 1260 entries