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Showing 1249 to 1260 of 1260 entries
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Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal.

Acta medica portuguesa

Dias MC, Dos Reis RS, Santos JV, Nunes AP, Ferreira P, Maia B, Fragata I, Reis J, Lopes JR, Cruz L, Santo G, Machado E, Gabriel D, Felgueiras R, Dória HM, Carneiro A, Correia M, Veloso LM, Barros P, Gregorio T, Carvalho A, Ribeiro M, Teotonio P, Neto L, E Melo TP, Canhao P, Filipe JP, Moreira G, Azevedo E, Silva ML, Costa EC, Oliveira G, Pereira L, Neves L, Rodrigues M, Marto JP, Calado S, Grenho F, Branco G, Baptista T, Rocha J, Ferreira C, Pinho J, Amorim JM, Araujo JM, Neiva RM, Viana J, Lobo M, Freitas A, Cruz VT, Sargento-Freitas J, Lopes JC.
PMID: 34499849
Acta Med Port. 2021 Sep 09; doi: 10.20344/amp.15031. Epub 2021 Sep 09.

INTRODUCTION: Since the publication of endovascular treatment trials and European Stroke Guidelines, Portugal has re-organized stroke healthcare. The nine centers performing endovascular treatment are not equally distributed within the country, which may lead to differential access to endovascular treatment....

Theoretical insights into the DNA repair function of .

Biophysics and physicobiology

Sato R, Mori Y, Matsui R, Okimoto N, Yamamoto J, Taiji M.
PMID: 33194514
Biophys Physicobiol. 2020 Sep 04;17:113-124. doi: 10.2142/biophysico.BSJ-2020010. eCollection 2020.

Following the discovery of cryptochrome-DASH (CRYD) as a new type of blue-light receptor cryptochrome, theoretical and experimental findings on CRYD have been reported. Early studies identified CRYD as highly homologous to the DNA repair enzyme photolyases (PLs), suggesting the...

A case of simultaneous laparoscopic surgery for double cancer comprising multiple early gastric cancer and advanced sigmoid colon cancer after revascularization.

Surgical case reports

Takiguchi K, Furuya S, Sudo M, Hirayama K, Saito R, Yamamoto A, Shoda K, Akaike H, Hosomura N, Kawaguchi Y, Amemiya H, Kawaida H, Kono H, Ichikawa D.
PMID: 33834304
Surg Case Rep. 2021 Apr 08;7(1):88. doi: 10.1186/s40792-021-01161-3.

BACKGROUND: Traditionally, the surgery for simultaneous double cancer of the stomach and colon required a large incision to the upper and lower region of the abdomen. In this case, an artificial blood vessel was located under the skin after...

Realistic computer modelling of stent retriever thrombectomy: a hybrid finite-element analysis-smoothed particle hydrodynamics model.

Journal of the Royal Society, Interface

Mousavi J S SM, Faghihi D, Sommer K, Bhurwani MMS, Patel TR, Santo B, Waqas M, Ionita C, Levy EI, Siddiqui AH, Tutino VM.
PMID: 34905967
J R Soc Interface. 2021 Dec;18(185):20210583. doi: 10.1098/rsif.2021.0583. Epub 2021 Dec 15.

Stent retriever thrombectomy is a pre-eminent treatment modality for large vessel ischaemic stroke. Simulation of thrombectomy could help understand stent and clot mechanics in failed cases and provide a digital testbed for the development of new, safer devices. Here,...

Treatment of rheumatoid arthritis after regression of lymphoproliferative disorders in patients treated with methotrexate: a retrospective, multi-center descriptive study.

Modern rheumatology

Nakano K, Tanaka Y, Saito K, Kaneko Y, Saito S, Tanaka M, Saito R, Fujii T, Kuramoto N, Sugimoto N, Takada H, Harigai M, Sasaki S, Suzuki Y.
PMID: 34919717
Mod Rheumatol. 2020 Dec 07; doi: 10.1080/14397595.2020.1847775. Epub 2020 Dec 07.

OBJECTIVES: To identify the optimal treatment for rheumatoid arthritis (RA) after the regression of lymphoproliferative disorders (LPDs).METHODS: The subjects were 232 patients with RA who developed LPD between 2000 and 2017 at seven hospitals participating in the LPD-WG study....

Effect of Inpatient and Outpatient Pneumonia on Mobility Disability, Gait Speed, and Physical Activity in Older Adults.

Journal of clinical medicine

Brown J, Sato R, Morley JE.
PMID: 33809731
J Clin Med. 2021 Mar 16;10(6). doi: 10.3390/jcm10061236.

Pathophysiological changes caused by pneumonia may influence physical functioning in older adults. This study was a secondary analysis of the Lifestyle Interventions and Independence for Elders (LIFE) Study. The LIFE Study included 1635 individuals over an average follow-up of...

Dynamic Polymer Free Volume Monitored by Single-Molecule Spectroscopy of a Dual Fluorescent Flapping Dopant.

Journal of the American Chemical Society

Goto Y, Omagari S, Sato R, Yamakado T, Achiwa R, Dey N, Suga K, Vacha M, Saito S.
PMID: 34448563
J Am Chem Soc. 2021 Sep 08;143(35):14306-14313. doi: 10.1021/jacs.1c06428. Epub 2021 Aug 27.

Single-molecule spectroscopy (SMS) of a dual fluorescent flapping molecular probe (N-FLAP) enabled real-time nanoscale monitoring of local free volume dynamics in polystyrenes. The SMS study was realized by structural improvement of a previously reported flapping molecule by nitrogen substitution,...

Comparison of gene expression and activation of transcription factors in organoid-derived monolayer intestinal epithelial cells and organoids.

Bioscience, biotechnology, and biochemistry

Takahashi Y, Inoue Y, Kuze K, Sato S, Shimizu M, Kiyono H, Yamauchi Y, Sato R.
PMID: 34297057
Biosci Biotechnol Biochem. 2021 Sep 22;85(10):2137-2144. doi: 10.1093/bbb/zbab136.

Intestinal organoids better represent in vivo intestinal properties than conventionally used established cell lines in vitro. However, they are maintained in three-dimensional culture conditions that may be accompanied by handling complexities. We characterized the properties of human organoid-derived two-dimensionally...

Bilateral lung transplantation in a 9-year-old girl with bronchopulmonary dysplasia with pulmonary hypertension.

Pediatric pulmonology

Ota C, Saito R, Tominaga J, Iwasawa S, Hirama T, Matsuda Y, Ono K, Onoki T, Kimura M, Kawabata Y, Okada Y.
PMID: 34350735
Pediatr Pulmonol. 2021 Oct;56(10):3417-3421. doi: 10.1002/ppul.25597. Epub 2021 Aug 05.

BACKGROUND: Bronchopulmonary dysplasia (BPD) is a chronic respiratory disease that occurs in premature infants and the prognosis is variable depending on the comorbidities including fibrosis, emphysema, or pulmonary hypertension (PH). We present a case of a 9-year-old girl who...

Dual kinetics of OATP2B1: Inhibitory potency and pH-dependence of OATP2B1 inhibitors.

Drug metabolism and pharmacokinetics

Sato R, Akiyoshi T, Morita T, Katayama K, Yajima K, Kataoka H, Imaoka A, Ohtani H.
PMID: 34619547
Drug Metab Pharmacokinet. 2021 Dec;41:100416. doi: 10.1016/j.dmpk.2021.100416. Epub 2021 Aug 04.

Organic anion transporting polypeptide (OATP) 2B1 is expressed in the intestine and liver, and OATP2B1-mediated transport of estrone 3-sulfate is pH-dependent and consists of: the high-affinity component (Hc) and low-affinity component (Lc). This study aimed to evaluate the influence...

Reliability of IDH1-R132H and ATRX and/or p53 immunohistochemistry for molecular subclassification of Grade 2/3 gliomas.

Brain tumor pathology

Nishikawa T, Watanabe R, Kitano Y, Yamamichi A, Motomura K, Ohka F, Aoki K, Hirano M, Kato A, Yamaguchi J, Maeda S, Kibe Y, Saito R, Wakabayashi T, Kato Y, Sato S, Ogino T, Natsume A, Ito I.
PMID: 34826036
Brain Tumor Pathol. 2022 Jan;39(1):14-24. doi: 10.1007/s10014-021-00418-x. Epub 2021 Nov 26.

Since the World Health Organization 2016 classification (2016 WHO), genetic status has been incorporated into the diagnosis of Grade 2/3 gliomas (lower-grade gliomas). Therefore, immunohistochemistry (IHC) of IDH1-R132H, ATRX, and p53 have been used in place of genetic status....

A Novel Enrichment Program Using Cascading Mentorship to Increase Diversity in the Health Care Professions.

Afghani B, Santos R, Angulo M, Muratori W.
UIID-AD: 91
2013;88:1232-1238. doi: 10.1097/ACM.0b013e31829ed47e.

The authors describe an innovative summer enrichment program based on a cascading mentorship model to transfer knowledge and skills from faculty to medical students to undergraduate students and finally to high school students. The program was designed to give...

Showing 1249 to 1260 of 1260 entries