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Showing 13 to 24 of 1645 entries
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Origin of High Regio-, Diastereo-, and Enantioselectivities in 1,6-Addition of Azlactones to Dienyl N-Acylpyrroles: A Computational Study.

The Journal of organic chemistry

Yamanaka M, Sakata K, Yoshioka K, Uraguchi D, Ooi T.
PMID: 27997163
J Org Chem. 2017 Jan 06;82(1):541-548. doi: 10.1021/acs.joc.6b02572. Epub 2016 Dec 20.

Chiral P-spiro triaminoiminophosphorane (1) was developed to promote the highly regio-, diastereo-, and enantioselective 1,6- and 1,8-additions of azlactones (2·H) to dienyl and trienyl N-acylpyrroles (3 and 4). DFT calculations enabled us to gain deep insight into the whole...

Thermoregulation modulated by hypothalamic histamine in rats.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]

Sakata T, Yoshimatsu H, Kurokawa M.
PMID: 27517991
Inflamm Res. 1997 Mar;46:35-6. doi: 10.1007/s000110050046.

No abstract available.

Inhaled hydrogen ameliorates endotoxin-induced bowel dysfunction.

Acute medicine & surgery

Sakata H, Okamoto A, Aoyama-Ishikawa M, Yamashita H, Kohama K, Fujisaki N, Yamada T, Kotani J, Tsukahara K, Iida A, Nakao A.
PMID: 29123834
Acute Med Surg. 2016 Jun 14;4(1):38-45. doi: 10.1002/ams2.218. eCollection 2017 Jan.

AIM: Gastrointestinal dysmotility frequently occurs during sepsis and multiple organ failure, remaining a major cause of morbidity and mortality in critically ill patients. Previous studies have shown that hydrogen, a new therapeutic gas, can improve various organ damage associated...

Heterozygosity for leptin receptor (fa) accelerates hepatic triglyceride accumulation without hyperphagia in Zucker rats.

Obesity research & clinical practice

Himeno K, Seike M, Fukuchi S, Masaki T, Kakuma T, Sakata T, Yoshimatsu H.
PMID: 24345539
Obes Res Clin Pract. 2009 Mar;3(1):1-52. doi: 10.1016/j.orcp.2008.10.003.

SUMMARY: Leptin, ob gene product, and its receptors are involved in the regulation of peripheral lipid and glucose metabolism. The present study sought to clarify the functional role of peripheral leptin receptors in hepatic lipid metabolism through analysis of...

Expression and Localization of α-amylase in the Submandibular and Sublingual Glands of Mice.

Acta histochemica et cytochemica

Yamagishi R, Wakayama T, Nakata H, Adthapanyawanich K, Kumchantuek T, Yamamoto M, Iseki S.
PMID: 25320406
Acta Histochem Cytochem. 2014 Jun 28;47(3):95-102. doi: 10.1267/ahc.14005. Epub 2014 Jun 14.

In the major salivary glands of mice, acinar cells in the parotid gland (PG) are known to be the main site for the production of the digestive enzyme α-amylase, whereas α-amylase production in the submandibular gland (SMG) and sublingual...

Therapeutic effect of dienogest on adenosarcoma arising from endometriosis: a case report.

SpringerPlus

Tasaka N, Matsumoto K, Satoh T, Minaguchi T, Onuki M, Ochi H, Tanaka YO, Sakata A, Noguchi M, Yoshikawa H.
PMID: 24324925
Springerplus. 2013 Nov 20;2:618. doi: 10.1186/2193-1801-2-618. eCollection 2013.

Dienogest is a novel synthesized progestin used for treatment of endometriosis. This is the first case report describing a therapeutic effect of dienogest on a gynecologic malignancy. The patient was a 44-year-old woman with advanced adenosarcoma arising from the...

Evaluation of Fibrous Cap Rupture of Atherosclerotic Carotid Plaque with Thin-Slice Source Images of Time-of-Flight MR Angiography.

Annals of vascular diseases

Watanabe Y, Nagayama M, Sakata A, Okumura A, Amoh Y, Ishimori T, Nakashita S, Dodo Y.
PMID: 24995056
Ann Vasc Dis. 2014;7(2):127-33. doi: 10.3400/avd.oa.13-00101. Epub 2014 May 16.

OBJECTIVE: To investigate the ability of source image of time-of-flight magnetic resonance angiography (TOF-MRA) in the detection of fibrous cap rupture of atherosclerotic carotid plaques.MATERIALS AND METHODS: From the database of radiological information in our hospital, 35 patients who...

Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells.

Molecular metabolism

Engelstoft MS, Park WM, Sakata I, Kristensen LV, Husted AS, Osborne-Lawrence S, Piper PK, Walker AK, Pedersen MH, Nøhr MK, Pan J, Sinz CJ, Carrington PE, Akiyama TE, Jones RM, Tang C, Ahmed K, Offermanns S, Egerod KL, Zigman JM, Schwartz TW.
PMID: 24327954
Mol Metab. 2013 Sep 04;2(4):376-92. doi: 10.1016/j.molmet.2013.08.006. eCollection 2013.

The molecular mechanisms regulating secretion of the orexigenic-glucoregulatory hormone ghrelin remain unclear. Based on qPCR analysis of FACS-purified gastric ghrelin cells, highly expressed and enriched 7TM receptors were comprehensively identified and functionally characterized using in vitro, ex vivo and...

Can Platelet-Rich Plasma Protect Rat Achilles Tendons From the Deleterious Effects of Triamcinolone Acetonide?.

Orthopaedic journal of sports medicine

Muto T, Kokubu T, Mifune Y, Inui A, Sakata R, Harada Y, Takase F, Ueda Y, Kuroda R, Kurosaka M.
PMID: 26673355
Orthop J Sports Med. 2015 Jul 07;3(7):2325967115590968. doi: 10.1177/2325967115590968. eCollection 2015 Jul.

BACKGROUND: Triamcinolone acetonide (TA) injections are widely used for tendinitis but have deleterious effects, including tendon degeneration or tendon rupture.PURPOSE: To investigate whether adding platelet-rich plasma (PRP), a blood fraction that participates in tissue repair processes, to TA can...

Post-marketing surveillance data of thrombomodulin alfa: sub-analysis in patients with sepsis-induced disseminated intravascular coagulation.

Journal of intensive care

Eguchi Y, Gando S, Ishikura H, Saitoh D, Mimuro J, Takahashi H, Kitajima I, Tsuji H, Matsushita T, Tsujita R, Nagao O, Sakata Y.
PMID: 25520842
J Intensive Care. 2014 Apr 30;2(1):30. doi: 10.1186/2052-0492-2-30. eCollection 2014.

BACKGROUND: Thrombomodulin alfa (TM-α, recombinant thrombomodulin) significantly improved disseminated intravascular coagulation (DIC) when compared with heparin therapy in a phase III study. Post-marketing surveillance of TM-α was performed to evaluate the effects and safety in patients with sepsis-induced DIC.METHODS:...

Osteogenic Potential of Adipose-Derived Macrospheroids Cocultured with CD11b+ Monocytes.

The International journal of oral & maxillofacial implants

Nakata H, Yamamoto M, Okada E, Nagayama T, Miyasaka M, Kasugai S, Kuroda S.
PMID: 28518185
Int J Oral Maxillofac Implants. 2017 July/August;32(4):e231–e240. doi: 10.11607/jomi.4957. Epub 2017 May 18.

PURPOSE: Among potential cell-based therapies, adipose-derived stem cells (ASCs) have been proposed as a promising source of stem cells for tissue regeneration. Although many recent clinical trials have investigated the use of adipose tissue or ASCs in transplantation, analysis...

Spontaneous Oscillations and Synchronization of Active Droplets on a Water Surface via Marangoni Convection.

Langmuir : the ACS journal of surfaces and colloids

Chen YJ, Sadakane K, Sakuta H, Yao C, Yoshikawa K.
PMID: 28991482
Langmuir. 2017 Oct 31;33(43):12362-12368. doi: 10.1021/acs.langmuir.7b03061. Epub 2017 Oct 18.

Shape-oscillations and synchronization are intriguing phenomena in many biological and physical systems. Here, we report the rhythmic mechanical oscillations and synchronization of aniline oil droplets on a water phase, which is induced by Marangoni convection during transfer of the...

Showing 13 to 24 of 1645 entries