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Showing 1825 to 1834 of 1834 entries
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Fecal microbiota transplantation as therapy for recurrent Clostridioides difficile infection is associated with amelioration of delirium and accompanied by changes in fecal microbiota and the metabolome.

Anaerobe

Gotoh K, Sakaguchi Y, Kato H, Osaki H, Jodai Y, Wakuda M, Také A, Hayashi S, Morita E, Sugie T, Ito Y, Ohmiya N.
PMID: 34896553
Anaerobe. 2021 Dec 09;102502. doi: 10.1016/j.anaerobe.2021.102502. Epub 2021 Dec 09.

Recurrent Clostridioides difficile infection (rCDI) is a frustrating condition that may affect a person's quality of life for months. Microbiome-based therapy such as fecal microbiota transplantation (FMT) has been effective for the treatment of rCDI by correcting the imbalance...

Trends in voluntary vaccination coverage in a Japanese city.

Pediatrics international : official journal of the Japan Pediatric Society

Hoshina T, Kawase M, Watanabe S, Shibahara J, Kojiro M, Miyake T, Sakaguchi Y, Kajiwara Y, Kusuhara K.
PMID: 33780596
Pediatr Int. 2021 Dec;63(12):1466-1471. doi: 10.1111/ped.14712. Epub 2021 Nov 08.

BACKGROUND: Large numbers of patients with diseases preventable by voluntary vaccines have been reported in Japan. However, it is difficult to analyze the impact of voluntary vaccination on disease prevention, as governments do not aggregate the number of recipients...

Arid5a Promotes Immune Evasion by Augmenting Tryptophan Metabolism and Chemokine Expression.

Cancer immunology research

Parajuli G, Tekguc M, Wing JB, Hashimoto A, Okuzaki D, Hirata T, Sasaki A, Itokazu T, Handa H, Sugino H, Nishikawa Y, Metwally H, Kodama Y, Tanaka S, Sabe H, Yamashita T, Sakaguchi S, Kishimoto T, Hashimoto S.
PMID: 34006522
Cancer Immunol Res. 2021 Aug;9(8):862-876. doi: 10.1158/2326-6066.CIR-21-0014. Epub 2021 May 18.

The acquisition of mesenchymal traits leads to immune evasion in various cancers, but the underlying molecular mechanisms remain unclear. In this study, we found that the expression levels of AT-rich interaction domain-containing protein 5a (Arid5a), an RNA-binding protein, were...

Association of Time-Updated Anion Gap With Risk of Kidney Failure in Advanced CKD: A Cohort Study.

American journal of kidney diseases : the official journal of the National Kidney Foundation

Asahina Y, Sakaguchi Y, Kajimoto S, Hattori K, Doi Y, Oka T, Kaimori JY, Isaka Y.
PMID: 34280508
Am J Kidney Dis. 2021 Jul 16; doi: 10.1053/j.ajkd.2021.05.022. Epub 2021 Jul 16.

RATIONALE & OBJECTIVE: High anion gap acidosis frequently develops in patients with advanced chronic kidney disease (CKD) and might be involved in kidney injury. Its impact on kidney outcomes, however, has not been well studied. We sought to examine...

Nutritional assessments for ordinary medical care in patients with chronic liver disease.

Hepatology research : the official journal of the Japan Society of Hepatology

Taniguchi E, Kawaguchi T, Otsuka M, Uchida Y, Nagamatsu A, Itou M, Oriishi T, Ishii K, Imanaga M, Suetsugu T, Otsuyama J, Ibi R, Ono M, Tanaka S, Sata M.
PMID: 22827610
Hepatol Res. 2013 Feb;43(2):192-9. doi: 10.1111/j.1872-034X.2012.01055.x. Epub 2012 Jul 25.

AIM:   In patients with chronic liver disease who are at risk of malnutrition, simple and useful assessments for nutritional status should be established for ordinary medical care. The prognostic nutritional index (PNI) and controlling nutritional status (CONUT) are simple...

Hepatic actinomycosis after total pancreatectomy: A case report.

International journal of surgery case reports

Sakaguchi T, Hashimoto D, Satoi S, Yamamoto T, Yamaki S, Sekimoto M.
PMID: 34330068
Int J Surg Case Rep. 2021 Aug;85:106212. doi: 10.1016/j.ijscr.2021.106212. Epub 2021 Jul 20.

INTRODUCTION AND IMPORTANCE: Hepatic actinomycosis (HA) is a rare infection mimicking a malignancy. HA after total pancreatectomy for a pancreatic tumor has not been reported.CASE PRESENTATION: A 70-year-old woman with a history of gastrectomy and sigmoidectomy for benign lesions,...

Association between choriocapillaris flow deficit and choroidal neovascularization activity in eyes with myopic choroidal neovascularization.

Scientific reports

Uematsu S, Sakaguchi H, Sayanagi K, Ikuno Y, Yokoyama A, Asai T, Fukushima Y, Hara C, Sakimoto S, Nishida K.
PMID: 34754047
Sci Rep. 2021 Nov 09;11(1):21947. doi: 10.1038/s41598-021-01557-z.

Although choriocapillaris flow deficit (CFD) around choroidal neovascularization (CNV) is less associated with CNV activity in myopic eyes, no reports are investigating its size as an indicator of CNV activity. We investigated the relationship between CFD and high myopia-related...

Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation.

Nature

Saito A, Irie T, Suzuki R, Maemura T, Nasser H, Uriu K, Kosugi Y, Shirakawa K, Sadamasu K, Kimura I, Ito J, Wu J, Iwatsuki-Horimoto K, Ito M, Yamayoshi S, Loeber S, Tsuda M, Wang L, Ozono S, Butlertanaka EP, Tanaka YL, Shimizu R, Shimizu K, Yoshimatsu K, Kawabata R, Sakaguchi T, Tokunaga K, Yoshida I, Asakura H, Nagashima M, Kazuma Y, Nomura R, Horisawa Y, Yoshimura K, Takaori-Kondo A, Imai M, Tanaka S, Nakagawa S, Ikeda T, Fukuhara T, Kawaoka Y, Sato K.
PMID: 34823256
Nature. 2021 Nov 25; doi: 10.1038/s41586-021-04266-9. Epub 2021 Nov 25.

During the current coronavirus disease 2019 (COVID-19) pandemic, a variety of mutations have accumulated in the viral genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and, at the time of writing, four variants of concern are considered to...

Immune-mediated thrombocytopenia induced with durvalumab after chemoradiotherapy in a non-small cell lung cancer patient: A case report.

Thoracic cancer

Makiguchi T, Tanaka H, Kamata K, Taima K, Kurose A, Tasaka S.
PMID: 34405563
Thorac Cancer. 2021 Oct;12(20):2811-2814. doi: 10.1111/1759-7714.14106. Epub 2021 Aug 17.

We describe a case of a 60-year-old man with a prolonged thrombocytopenia during a durvalumab maintenance therapy after chemoradiotherapy for locally advanced non-small cell lung carcinoma. Bone marrow specimen was normoplastic with the marked megakaryocyte depletion, which was assumed...

Idiopathic eosinophilic pleurisy: A practical diagnostic approach.

Respiratory medicine case reports

Haraguchi T, Tashiro H, Takahashi K, Kurihara Y, Sadamatsu H, Miyahara N, Hiratsuka M, Kimura S, Sueoka-Aragane N.
PMID: 34401274
Respir Med Case Rep. 2021 May 20;33:101430. doi: 10.1016/j.rmcr.2021.101430. eCollection 2021.

A 37-year-old man with fever, cough, and dyspnea with no medical history developed an eosinophilic pleural effusion and blood eosinophilia. No evidence of malignancy or pathogens was detected in the pleural effusion, and the pleural specimen obtained by thoracoscopy...

Showing 1825 to 1834 of 1834 entries