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Showing 1405 to 1409 of 1409 entries
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Arid5a Promotes Immune Evasion by Augmenting Tryptophan Metabolism and Chemokine Expression.

Cancer immunology research

Parajuli G, Tekguc M, Wing JB, Hashimoto A, Okuzaki D, Hirata T, Sasaki A, Itokazu T, Handa H, Sugino H, Nishikawa Y, Metwally H, Kodama Y, Tanaka S, Sabe H, Yamashita T, Sakaguchi S, Kishimoto T, Hashimoto S.
PMID: 34006522
Cancer Immunol Res. 2021 Aug;9(8):862-876. doi: 10.1158/2326-6066.CIR-21-0014. Epub 2021 May 18.

The acquisition of mesenchymal traits leads to immune evasion in various cancers, but the underlying molecular mechanisms remain unclear. In this study, we found that the expression levels of AT-rich interaction domain-containing protein 5a (Arid5a), an RNA-binding protein, were...

Association of Time-Updated Anion Gap With Risk of Kidney Failure in Advanced CKD: A Cohort Study.

American journal of kidney diseases : the official journal of the National Kidney Foundation

Asahina Y, Sakaguchi Y, Kajimoto S, Hattori K, Doi Y, Oka T, Kaimori JY, Isaka Y.
PMID: 34280508
Am J Kidney Dis. 2021 Jul 16; doi: 10.1053/j.ajkd.2021.05.022. Epub 2021 Jul 16.

RATIONALE & OBJECTIVE: High anion gap acidosis frequently develops in patients with advanced chronic kidney disease (CKD) and might be involved in kidney injury. Its impact on kidney outcomes, however, has not been well studied. We sought to examine...

Hepatic actinomycosis after total pancreatectomy: A case report.

International journal of surgery case reports

Sakaguchi T, Hashimoto D, Satoi S, Yamamoto T, Yamaki S, Sekimoto M.
PMID: 34330068
Int J Surg Case Rep. 2021 Aug;85:106212. doi: 10.1016/j.ijscr.2021.106212. Epub 2021 Jul 20.

INTRODUCTION AND IMPORTANCE: Hepatic actinomycosis (HA) is a rare infection mimicking a malignancy. HA after total pancreatectomy for a pancreatic tumor has not been reported.CASE PRESENTATION: A 70-year-old woman with a history of gastrectomy and sigmoidectomy for benign lesions,...

Association between choriocapillaris flow deficit and choroidal neovascularization activity in eyes with myopic choroidal neovascularization.

Scientific reports

Uematsu S, Sakaguchi H, Sayanagi K, Ikuno Y, Yokoyama A, Asai T, Fukushima Y, Hara C, Sakimoto S, Nishida K.
PMID: 34754047
Sci Rep. 2021 Nov 09;11(1):21947. doi: 10.1038/s41598-021-01557-z.

Although choriocapillaris flow deficit (CFD) around choroidal neovascularization (CNV) is less associated with CNV activity in myopic eyes, no reports are investigating its size as an indicator of CNV activity. We investigated the relationship between CFD and high myopia-related...

Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation.

Nature

Saito A, Irie T, Suzuki R, Maemura T, Nasser H, Uriu K, Kosugi Y, Shirakawa K, Sadamasu K, Kimura I, Ito J, Wu J, Iwatsuki-Horimoto K, Ito M, Yamayoshi S, Loeber S, Tsuda M, Wang L, Ozono S, Butlertanaka EP, Tanaka YL, Shimizu R, Shimizu K, Yoshimatsu K, Kawabata R, Sakaguchi T, Tokunaga K, Yoshida I, Asakura H, Nagashima M, Kazuma Y, Nomura R, Horisawa Y, Yoshimura K, Takaori-Kondo A, Imai M, Tanaka S, Nakagawa S, Ikeda T, Fukuhara T, Kawaoka Y, Sato K.
PMID: 34823256
Nature. 2021 Nov 25; doi: 10.1038/s41586-021-04266-9. Epub 2021 Nov 25.

During the current coronavirus disease 2019 (COVID-19) pandemic, a variety of mutations have accumulated in the viral genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and, at the time of writing, four variants of concern are considered to...

Showing 1405 to 1409 of 1409 entries