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Showing 25 to 36 of 78 entries
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Publisher Correction: Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques.

Nature

Mercado NB, Zahn R, Wegmann F, Loos C, Chandrashekar A, Yu J, Liu J, Peter L, McMahan K, Tostanoski LH, He X, Martinez DR, Rutten L, Bos R, van Manen D, Vellinga J, Custers J, Langedijk JP, Kwaks T, Bakkers MJG, Zuijdgeest D, Huber SKR, Atyeo C, Fischinger S, Burke JS, Feldman J, Hauser BM, Caradonna TM, Bondzie EA, Dagotto G, Gebre MS, Hoffman E, Jacob-Dolan C, Kirilova M, Li Z, Lin Z, Mahrokhian SH, Maxfield LF, Nampanya F, Nityanandam R, Nkolola JP, Patel S, Ventura JD, Verrington K, Wan H, Pessaint L, Van Ry A, Blade K, Strasbaugh A, Cabus M, Brown R, Cook A, Zouantchangadou S, Teow E, Andersen H, Lewis MG, Cai Y, Chen B, Schmidt AG, Reeves RK, Baric RS, Lauffenburger DA, Alter G, Stoffels P, Mammen M, Van Hoof J, Schuitemaker H, Barouch DH.
PMID: 33469218
Nature. 2021 Feb;590(7844):E25. doi: 10.1038/s41586-020-03100-y.

No abstract available.

The FASTK family proteins fine-tune mitochondrial RNA processing.

PLoS genetics

Ohkubo A, Van Haute L, Rudler DL, Stentenbach M, Steiner FA, Rackham O, Minczuk M, Filipovska A, Martinou JC.
PMID: 34748562
PLoS Genet. 2021 Nov 08;17(11):e1009873. doi: 10.1371/journal.pgen.1009873. eCollection 2021 Nov.

Transcription of the human mitochondrial genome and correct processing of the two long polycistronic transcripts are crucial for oxidative phosphorylation. According to the tRNA punctuation model, nucleolytic processing of these large precursor transcripts occurs mainly through the excision of...

Ad26.COV2.S protects Syrian hamsters against G614 spike variant SARS-CoV-2 and does not enhance respiratory disease.

NPJ vaccines

van der Lubbe JEM, Rosendahl Huber SK, Vijayan A, Dekking L, van Huizen E, Vreugdenhil J, Choi Y, Baert MRM, Feddes-de Boer K, Izquierdo Gil A, van Heerden M, Dalebout TJ, Myeni SK, Kikkert M, Snijder EJ, de Waal L, Stittelaar KJ, Tolboom JTBM, Serroyen J, Muchene L, van der Fits L, Rutten L, Langedijk JPM, Barouch DH, Schuitemaker H, Zahn RC, Wegmann F.
PMID: 33741993
NPJ Vaccines. 2021 Mar 19;6(1):39. doi: 10.1038/s41541-021-00301-y.

Previously we have shown that a single dose of recombinant adenovirus serotype 26 (Ad26) vaccine expressing a prefusion stabilized SARS-CoV-2 spike antigen (Ad26.COV2.S) is immunogenic and provides protection in Syrian hamster and non-human primate SARS-CoV-2 infection models. Here, we...

Activated CD4.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Duizendstra AA, de Knegt RJ, Mancham S, Klepper M, Roelen DL, Brand-Schaaf SH, Boor PP, Doukas M, de Man RA, Sprengers D, Peppelenbosch MP, Betjes MGH, Kwekkeboom J, Litjens NHR.
PMID: 34081828
Liver Transpl. 2021 Jun 03; doi: 10.1002/lt.26188. Epub 2021 Jun 03.

Spontaneous operational tolerance to the allograft develops in a proportion of liver transplantation (LT) recipients weaned off immunosuppressive (IS) drugs. Several studies have investigated whether peripheral blood circulating T cells could play a role in the development or identify...

Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses.

NPJ vaccines

Bos R, Rutten L, van der Lubbe JEM, Bakkers MJG, Hardenberg G, Wegmann F, Zuijdgeest D, de Wilde AH, Koornneef A, Verwilligen A, van Manen D, Kwaks T, Vogels R, Dalebout TJ, Myeni SK, Kikkert M, Snijder EJ, Li Z, Barouch DH, Vellinga J, Langedijk JPM, Zahn RC, Custers J, Schuitemaker H.
PMID: 34580303
NPJ Vaccines. 2020 Sep 28;5(1):91. doi: 10.1038/s41541-020-00243-x.

Development of effective preventative interventions against SARS-CoV-2, the etiologic agent of COVID-19 is urgently needed. The viral surface spike (S) protein of SARS-CoV-2 is a key target for prophylactic measures as it is critical for the viral replication cycle...

Generalizability of Homeopathic Prognostic Factor Research Outcome in COVID-19 Treatment: Comparison of Data.

Homeopathy : the journal of the Faculty of Homeopathy

Rutten L, Miglani A, Gold P, Manchanda RK, Chakraborty M, Meena BS, Sharma K, Gupta M, Sharma B, Sharma A, Rani P, Singh RK.
PMID: 34666410
Homeopathy. 2021 Oct 19; doi: 10.1055/s-0041-1732307. Epub 2021 Oct 19.

BACKGROUND/OBJECTIVE:  During the coronavirus disease 2019 (COVID-19) pandemic, several homeopathic prognostic factor research (PFR) projects have been undertaken. We found two projects with comparable outcomes to assess consistency and possible flaws.METHODS:  Two comparisons were made. (1) Outcome of a...

The FASTK family proteins fine-tune mitochondrial RNA processing.

PLoS genetics

Ohkubo A, Van Haute L, Rudler DL, Stentenbach M, Steiner FA, Rackham O, Minczuk M, Filipovska A, Martinou JC.
PMID: 34748562
PLoS Genet. 2021 Nov 08;17(11):e1009873. doi: 10.1371/journal.pgen.1009873. eCollection 2021 Nov.

Transcription of the human mitochondrial genome and correct processing of the two long polycistronic transcripts are crucial for oxidative phosphorylation. According to the tRNA punctuation model, nucleolytic processing of these large precursor transcripts occurs mainly through the excision of...

Optical bit-pattern recognition by use of dynamic gratings in erbium-doped fiber.

Optics letters

Wey JS, Butler DL, Rush NW, Burdge GL, Goldhar J.
PMID: 18188356
Opt Lett. 1997 Dec 01;22(23):1757-9. doi: 10.1364/ol.22.001757.

We present a novel optical bit-pattern-recognition technique that uses erbium-doped fiber at room temperature. Counterpropagating beams write a patterned gain-depletion grating in pumped erbium-doped fiber. This grating, recorded in the erbium gain medium, can be used for correlation with...

SMAD6 transduces endothelial cell flow responses required for blood vessel homeostasis.

Angiogenesis

Ruter DL, Liu Z, Ngo KM, X S, Marvin A, Buglak DB, Kidder EJ, Bautch VL.
PMID: 33779885
Angiogenesis. 2021 May;24(2):387-398. doi: 10.1007/s10456-021-09777-7. Epub 2021 Mar 29.

Fluid shear stress provided by blood flow instigates a transition from active blood vessel network expansion during development, to vascular homeostasis and quiescence that is important for mature blood vessel function. Here we show that SMAD6 is required for...

Microwave optical modulation by using the electro-optic effect in total internal reflection at the critical angle.

Optics letters

Butler DL, Burdge GL, Lee CH, Simon HJ.
PMID: 19794739
Opt Lett. 1992 Aug 15;17(16):1125-7. doi: 10.1364/ol.17.001125.

We demonstrate microwave modulation of an optical beam by using the electro-optic effect in total internal reflection near the critical angle. An internally reflected mode-locked laser beam and a microwave field electrooptically interact near the surface of a KDP...

Technique for measurement of the Raman gain coefficient in optical fibers.

Optics letters

Mahgerefteh D, Butler DL, Goldhar J, Rosenberg B, Burdge GL.
PMID: 19881881
Opt Lett. 1996 Dec 15;21(24):2026-8. doi: 10.1364/ol.21.002026.

We demonstrate a simple, novel technique for measurement of the Raman gain spectrum in optical fibers. We measure the stimulated Raman scattered power generated by a square pulse as a function of its pulse width. Because of fiber dispersion,...

Proteomic analysis of breast tissue and nipple aspirate fluid for breast cancer detection.

Biomarkers in medicine

Ruhlen RL, Sauter ER.
PMID: 20477400
Biomark Med. 2007 Aug;1(2):251-60. doi: 10.2217/17520363.1.2.251.

Clinical proteomics has great promise, but many hurdles. Proteomic approaches may prove to be the answer to decades of frustrating searches for markers that are specific and selective for breast cancer. In order to achieve this goal, the challenge...

Showing 25 to 36 of 78 entries