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Showing 9985 to 9996 of 18495 entries
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Toxic effects of subacute exposure to acrylamide on motor endplates of the gastrocnemius in rats.

Toxicology

Bai Y, Gu Z, Zhang T, Luo Y, Zhang C, Luo L, Ma Y, Liu J.
PMID: 34509579
Toxicology. 2021 Oct;462:152934. doi: 10.1016/j.tox.2021.152934. Epub 2021 Sep 09.

Acrylamide (ACR) is a recognized toxin that is known to induce neurotoxicity in humans and experimental animals. This study aimed to investigate the toxic effects of subacute exposure of the motor endplate (MEP) of the gastrocnemius in rats to...

Tandem nanobody: A feasible way to improve the capacity of affinity chromatography.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Huang Y, Fu J, Zhong Y, Shuai W, Zhang H, Li Y, He Q, Tu Z.
PMID: 33839466
J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Mar 29;1173:122678. doi: 10.1016/j.jchromb.2021.122678. Epub 2021 Mar 29.

Nanobodies, referred to the binding domain of the heavy-chain-only antibodies, are the smallest antigen recognition unit. The molecular weight of monomeric nanobodies is about one-tenth of the conventional antibodies. The small size of nanobodies facilitates genetic manipulation and recombinant...

An extensive review: How starch and gluten impact dough machinability and resultant bread qualities.

Critical reviews in food science and nutrition

Hu X, Cheng L, Hong Y, Li Z, Li C, Gu Z.
PMID: 34423705
Crit Rev Food Sci Nutr. 2021 Aug 23;1-12. doi: 10.1080/10408398.2021.1969535. Epub 2021 Aug 23.

Wheat flour can form dough with a three-dimensional viscoelastic structure that is responsible for gas holding during fermentation and oven-rise, creating a typical fixed, open-cell foam structure of bread after baking. As the major components of dough, the continuous...

Durability of SARS-CoV-2-Specific T-Cell Responses at 12 Months Postinfection.

The Journal of infectious diseases

Lu Z, Laing ED, Pena DaMata J, Pohida K, Tso MS, Samuels EC, Epsi NJ, Dorjbal B, Lake C, Richard SA, Maves RC, Lindholm DA, Rozman JS, English C, Huprikar N, Mende K, Colombo RE, Colombo CJ, Broder CC, Ganesan A, Lanteri CA, Agan BK, Tribble D, Simons MP, Dalgard CL, Blair PW, Chenoweth J, Pollett SD, Snow AL, Burgess TH, Malloy AMW.
PMID: 34673956
J Infect Dis. 2021 Dec 15;224(12):2010-2019. doi: 10.1093/infdis/jiab543.

BACKGROUND: Characterizing the longevity and quality of cellular immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enhances understanding of coronavirus disease 2019 (COVID-19) immunity that influences clinical outcomes. Prior studies suggest SARS-CoV-2-specific T cells are present in...

Age-Related Changes in Body Composition and Bone Mineral Density and Their Relationship with the Duration of Diabetes and Glycaemic Control in Type 2 Diabetes.

Diabetes, metabolic syndrome and obesity : targets and therapy

Tang Y, Gong L, Chen X, Du Z, Hu J, Xu Z, Wu J, Li Q, Wang Z.
PMID: 33293843
Diabetes Metab Syndr Obes. 2020 Dec 01;13:4699-4710. doi: 10.2147/DMSO.S278425. eCollection 2020.

PURPOSE: To investigate age-related changes in body composition (BC) and bone mineral density (BMD) in type 2 diabetes (T2D) and analyse whether diabetes duration or glycaemic control affects these factors.PATIENTS AND METHODS: We enrolled 1474 hospitalized T2D patients (817...

The Role of Cognitive Impairment on Physical Therapy Attendance and Outcomes in Multiple Sclerosis.

Journal of neurologic physical therapy : JNPT

Gomes KE, Ruiz JA, Raskin SA, Turner AP, DelMastro HM, Neto LO, Gromisch ES.
PMID: 34507342
J Neurol Phys Ther. 2021 Sep 09; doi: 10.1097/NPT.0000000000000375. Epub 2021 Sep 09.

BACKGROUND AND PURPOSE: Many persons with multiple sclerosis (PwMS) experience cognitive impairments, which may affect their ability to engage in physical therapy. There is limited information on how cognitive impairments are associated with PwMS' ability to participate and improve...

Association of postoperative delirium with cognitive outcomes: A meta-analysis.

Journal of clinical anesthesia

Huang H, Li H, Zhang X, Shi G, Xu M, Ru X, Chen Y, Patel MB, Ely EW, Lin S, Zhang G, Zhou J.
PMID: 34482263
J Clin Anesth. 2021 Dec;75:110496. doi: 10.1016/j.jclinane.2021.110496. Epub 2021 Sep 02.

STUDY OBJECTIVE: To determine the association between postoperative delirium (POD) and cognitive outcomes at least 1 month after surgery in elderly patients, and synthesize the dynamic risk trajectory of cognition impairment after POD.DESIGN: Meta-analysis searching PubMed, Cochrane and EMBASE...

High expression levels of centromere protein A plus upregulation of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling pathway affect chemotherapy response and prognosis in patients with breast cancer.

Oncology letters

Zhang S, Xie Y, Tian T, Yang Q, Zhou Y, Qiu J, Xu L, Wen N, Lv Q, Du Z.
PMID: 33841571
Oncol Lett. 2021 May;21(5):410. doi: 10.3892/ol.2021.12671. Epub 2021 Mar 22.

Centromere proteins (CENPs) are involved in mitosis, and

Flavor Formation in Chinese Rice Wine (Huangjiu): Impacts of the Flavor-Active Microorganisms, Raw Materials, and Fermentation Technology.

Frontiers in microbiology

Yang Y, Hu W, Xia Y, Mu Z, Tao L, Song X, Zhang H, Ni B, Ai L.
PMID: 33281774
Front Microbiol. 2020 Nov 13;11:580247. doi: 10.3389/fmicb.2020.580247. eCollection 2020.

Huangjiu (Chinese rice wine) has been consumed for centuries in Asian countries and is known for its unique flavor and subtle taste. The flavor compounds of Huangjiu are derived from a wide range of sources, such as raw materials,...

Metal-Organic Framework-Derived Fe-Doped Ni.

ACS applied materials & interfaces

Srinivas K, Chen Y, Wang B, Yu B, Lu Y, Su Z, Zhang W, Yang D.
PMID: 33258579
ACS Appl Mater Interfaces. 2020 Dec 16;12(50):55782-55794. doi: 10.1021/acsami.0c13836. Epub 2020 Dec 01.

Strategic design and fabrication of a highly efficient and cost-effective bifunctional electrocatalyst is of great significance in water electrolysis in order to produce sustainable hydrogen fuel in a large scale. However, it is still challenging to develop a stable,...

IL-30 ameliorates imiquimod and K14-VEGF induced psoriasis-like disease by inhibiting both innate and adaptive immunity disorders.

Biochemical and biophysical research communications

Liu X, Hu Z, Zhang J, Ma T, Wu W, Wei X, Wang Z, Zhen H, Zhou H, Huang N, Li J.
PMID: 34597998
Biochem Biophys Res Commun. 2021 Nov 19;579:97-104. doi: 10.1016/j.bbrc.2021.09.042. Epub 2021 Sep 21.

Psoriasis is a severe skin disease with significant physical and psychological health consequences. As a typical type of immune disease, both innate and adaptive immunity disorders play key roles in the development of psoriasis. Interleukin (IL)-30 was thought as...

Mechanistic dissection of spatial organization in NF-κB signaling pathways by hybrid simulations.

Integrative biology : quantitative biosciences from nano to macro

Wu Y, Dhusia K, Su Z.
PMID: 33893499
Integr Biol (Camb). 2021 May 18;13(5):109-120. doi: 10.1093/intbio/zyab006.

The nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is one of the most important transcription factors involved in the regulation of inflammatory signaling pathways. Inappropriate activation of these pathways has been linked to autoimmunity and cancers. Emerging experimental...

Showing 9985 to 9996 of 18495 entries