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Showing 13 to 24 of 95 entries
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Red blood cell oxidative stress impairs oxygen delivery and induces red blood cell aging.

Frontiers in physiology

Mohanty JG, Nagababu E, Rifkind JM.
PMID: 24616707
Front Physiol. 2014 Feb 28;5:84. doi: 10.3389/fphys.2014.00084. eCollection 2014.

Red Blood Cells (RBCs) need to deform and squeeze through narrow capillaries. Decreased deformability of RBCs is, therefore, one of the factors that can contribute to the elimination of aged or damaged RBCs from the circulation. This process can...

A Multicohort Open-label Phase II Trial of Bipolar Androgen Therapy in Men with Metastatic Castration-resistant Prostate Cancer (RESTORE): A Comparison of Post-abiraterone Versus Post-enzalutamide Cohorts.

European urology

Markowski MC, Wang H, Sullivan R, Rifkind I, Sinibaldi V, Schweizer MT, Teply BA, Ngomba N, Fu W, Carducci MA, Paller CJ, Marshall CH, Eisenberger MA, Luo J, Antonarakis ES, Denmeade SR.
PMID: 32624280
Eur Urol. 2021 May;79(5):692-699. doi: 10.1016/j.eururo.2020.06.042. Epub 2020 Jul 02.

BACKGROUND: Cyclic high-dose testosterone injections, also known as bipolar androgen therapy (BAT), is a novel treatment strategy for patients with metastatic castration-resistant prostate cancer (mCRPC). BAT has shown clinical activity in prior studies enrolling men with mCRPC and may...

Systems and the structure of meaning.

The American journal of psychiatry

Rifkin A.
PMID: 3605420
Am J Psychiatry. 1987 Jul;144(7):971-2. doi: 10.1176/ajp.144.7.aj1447971.

No abstract available.

New genomic resources and comparative analyses reveal differences in floral gene expression in selfing and outcrossing Collinsia sister species.

G3 (Bethesda, Md.)

Frazee LJ, Rifkin J, Maheepala DC, Grant AG, Wright S, Kalisz S, Litt A, Spigler R.
PMID: 34014319
G3 (Bethesda). 2021 Aug 07;11(8). doi: 10.1093/g3journal/jkab177.

The evolutionary transition from outcross- to self-fertilization is one of the most common in angiosperms and is often associated with a parallel shift in floral morphological and developmental traits, such as reduced flower size and pollen to ovule ratios,...

Design, Development, and Evaluation of a Telemedicine Platform for Patients With Sleep Apnea (Ognomy): Design Science Research Approach.

JMIR formative research

Mulgund P, Sharman R, Rifkin D, Marrazzo S.
PMID: 34279237
JMIR Form Res. 2021 Jul 19;5(7):e26059. doi: 10.2196/26059.

BACKGROUND: With an aging population and the escalating cost of care, telemedicine has become a societal imperative. Telemedicine alternatives are especially relevant to patients seeking care for sleep apnea, with its prevalence approaching one billion cases worldwide. Increasing awareness...

Perceptions of Telehealth vs In-Person Visits Among Older Adults With Advanced Kidney Disease, Care Partners, and Clinicians.

JAMA network open

Ladin K, Porteny T, Perugini JM, Gonzales KM, Aufort KE, Levine SK, Wong JB, Isakova T, Rifkin D, Gordon EJ, Rossi A, Koch-Weser S, Weiner DE.
PMID: 34870680
JAMA Netw Open. 2021 Dec 01;4(12):e2137193. doi: 10.1001/jamanetworkopen.2021.37193.

IMPORTANCE: Telehealth has been posited as a cost-effective means for improving access to care for persons with chronic conditions, including kidney disease. Perceptions of telehealth among older patients with chronic illness, their care partners, and clinicians are largely unknown...

Alma Ata after 40 years: Primary Health Care and Health for All-from consensus to complexity.

BMJ global health

Rifkin SB.
PMID: 30622747
BMJ Glob Health. 2018 Dec 20;3:e001188. doi: 10.1136/bmjgh-2018-001188. eCollection 2018.

Forty years ago, the 134 national government members of the WHO signed the Alma Ata Declaration. The Declaration made Primary Health Care (PHC) the official health policy of all members countries. Emerging from the conference was the consensus that...

Choroidal nonperfusion on optical coherence tomography angiography in a case of unilateral posterior segment ocular sarcoidosis misdiagnosed as MEWDS.

American journal of ophthalmology case reports

Levine ES, Mendonça LSM, Baumal CR, Chin AT, Rifkin L, Waheed NK.
PMID: 33024892
Am J Ophthalmol Case Rep. 2020 Sep 25;20:100944. doi: 10.1016/j.ajoc.2020.100944. eCollection 2020 Dec.

PURPOSE: To report a case of presumed ocular sarcoidosis initially presenting with features of multiple evanescent white dot syndrome (MEWDS) with atypical optical coherence tomography angiography (OCTA) findings.OBSERVATIONS: A 23 year-old woman presented with a unilateral central scotoma, photophobia,...

The role of LTBPs in TGF beta signaling.

Developmental dynamics : an official publication of the American Association of Anatomists

Rifkin D, Sachan N, Singh K, Sauber E, Tellides G, Ramirez F.
PMID: 33742701
Dev Dyn. 2022 Jan;251(1):95-104. doi: 10.1002/dvdy.331. Epub 2021 Mar 25.

The purpose of this review is to discuss the transforming growth factor beta (TGFB) binding proteins (LTBP) with respect to their participation in the activity of TGFB. We first describe pertinent aspects of the biology and cell function of...

The pathophysiology of extracellular hemoglobin associated with enhanced oxidative reactions.

Frontiers in physiology

Rifkind JM, Mohanty JG, Nagababu E.
PMID: 25642190
Front Physiol. 2015 Jan 14;5:500. doi: 10.3389/fphys.2014.00500. eCollection 2014.

Hemoglobin (Hb) continuously undergoes autoxidation producing superoxide which dismutates into hydrogen peroxide (H2O2) and is a potential source for subsequent oxidative reactions. Autoxidation is most pronounced under hypoxic conditions in the microcirculation and for unstable dimers formed at reduced...

Toward a new understanding of poverty alleviation.

Tropical doctor

Rifkin SB.
PMID: 9133781
Trop Doct. 1997 Apr;27(2):66-7. doi: 10.1177/004947559702700202.

No abstract available.

Pentoxifylline, Ciprofloxacin and Dexamethasone Improve the Ineffective Hematopoiesis in Myelodysplastic Syndrome Patients; Malignancy.

Hematology (Amsterdam, Netherlands)

Raza A, Qawi H, Andric T, Dar S, Lisak L, Huang RW, Venugopal P, Gezer S, Gregory SA, Hsu WT, Loew J, Robin E, Rifkin S, Shah R, Divgi A, Taylor R, Grosset A.
PMID: 11399622
Hematology. 2000;5(4):275-284. doi: 10.1080/10245332.2000.11746517.

Twenty-five patients with a diagnosis of myelodysplastic syndromes (MDS) were randomized to either begin therapy with pentoxifylline, ciprofloxacin and dexamethasone (PCD) immediately (10 patients) or after a 12 week observation period (control arm, 15 patients). PCD was administered with...

Showing 13 to 24 of 95 entries