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Showing 181 to 190 of 190 entries
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The Role of Cancer Stem Cells and Mechanical Forces in Ovarian Cancer Metastasis.

Cancers

Bregenzer ME, Horst EN, Mehta P, Novak CM, Repetto T, Mehta G.
PMID: 31323899
Cancers (Basel). 2019 Jul 18;11(7). doi: 10.3390/cancers11071008.

Ovarian cancer is an extremely lethal gynecologic disease; with the high-grade serous subtype predominantly associated with poor survival rates. Lack of early diagnostic biomarkers and prevalence of post-treatment recurrence, present substantial challenges in treating ovarian cancers. These cancers are...

Structural and functional studies of the metalloregulator Fur identify a promoter-binding mechanism and its role in .

Communications biology

Pérard J, Nader S, Levert M, Arnaud L, Carpentier P, Siebert C, Blanquet F, Cavazza C, Renesto P, Schneider D, Maurin M, Coves J, Crouzy S, Michaud-Soret I.
PMID: 30271974
Commun Biol. 2018 Jul 17;1:93. doi: 10.1038/s42003-018-0095-6. eCollection 2018.

No abstract available.

Fast Fiber Orientation Estimation in Diffusion MRI from kq-Space Sampling and Anatomical Priors.

Journal of imaging

Pesce M, Repetti A, Auría A, Daducci A, Thiran JP, Wiaux Y.
PMID: 34821857
J Imaging. 2021 Oct 27;7(11). doi: 10.3390/jimaging7110226.

High spatio-angular resolution diffusion MRI (dMRI) has been shown to provide accurate identification of complex neuronal fiber configurations, albeit, at the cost of long acquisition times. We propose a method to recover intra-voxel fiber configurations at high spatio-angular resolution...

Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior.

Cell reports

Klatt O, Repetto D, Brockhaus J, Reissner C, El Khallouqi A, Rohlmann A, Heine M, Missler M.
PMID: 34133920
Cell Rep. 2021 Jun 15;35(11):109266. doi: 10.1016/j.celrep.2021.109266.

Neurexins are key organizer molecules that regulate synaptic function and are implicated in autism and schizophrenia. β-neurexins interact with numerous cell adhesion and receptor molecules, but their neuronal localization remains elusive. Using single-molecule tracking and high-resolution microscopy to detect...

Unilateral Nephrectomy Stimulates ERK and Is Associated With Enhanced Na Transport.

Frontiers in physiology

Repetti R, Majumder N, De Oliveira KC, Meth J, Yangchen T, Sharma M, Srivastava T, Rohatgi R.
PMID: 33633581
Front Physiol. 2021 Feb 03;12:583453. doi: 10.3389/fphys.2021.583453. eCollection 2021.

Nephron loss initiates compensatory hemodynamic and cellular effects on the remaining nephrons. Increases in single nephron glomerular filtration rate and tubular flow rate exert higher fluid shear stress (FSS) on tubules. In principal cell (PC) culture models FSS induces...

Type 2 diabetes mellitus increases the risk of hepatic fibrosis in individuals with obesity and nonalcoholic fatty liver disease.

Obesity (Silver Spring, Md.)

Barb D, Repetto EM, Stokes ME, Shankar SS, Cusi K.
PMID: 34553836
Obesity (Silver Spring). 2021 Nov;29(11):1950-1960. doi: 10.1002/oby.23263. Epub 2021 Sep 23.

OBJECTIVE: This study assessed the impact of diabetes mellitus (DM) on nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) with advanced fibrosis prevalence in adults with overweight or obesity in the United States.METHODS: Participants (National Health and Nutrition...

Reconstruction of the Swine Pulmonary Artery Using a Graft Engineered With Syngeneic Cardiac Pericytes.

Frontiers in bioengineering and biotechnology

Alvino VV, Thomas AC, Ghorbel MT, Rapetto F, Narayan SA, Kilcooley M, Iacobazzi D, Carrabba M, Fagnano M, Cathery W, Avolio E, Caputo M, Madeddu P.
PMID: 34568300
Front Bioeng Biotechnol. 2021 Sep 09;9:715717. doi: 10.3389/fbioe.2021.715717. eCollection 2021.

The neonatal heart represents an attractive source of regenerative cells. Here, we report the results of a randomized, controlled, investigator-blinded preclinical study, which assessed the safety and effectiveness of a matrix graft cellularized with cardiac pericytes (CPs) in a...

When first line treatment of neonatal infection is not enough: blood culture and resistance patterns in neonates requiring second line antibiotic therapy in Bangui, Central African Republic.

BMC pediatrics

Nebbioso A, Ogundipe OF, Repetto EC, Mekiedje C, Sanke-Waigana H, Ngaya G, Ingelbeen B, Gil-Cuesta J.
PMID: 34903185
BMC Pediatr. 2021 Dec 13;21(1):570. doi: 10.1186/s12887-021-02911-w.

BACKGROUND: Infectious diseases account for the third most common cause of neonatal deaths. Globally, antibiotic resistance (ABR) has been increasingly challenging neonatal sepsis treatment, with 26 to 84% of gram-negative bacteria resistant to third-generation cephalosporins. In sub-Saharan Africa, limited...

Targeted proteomics to identify cadmium-induced protein modifications in Glomus mosseae-inoculated pea roots.

The New phytologist

Repetto O, Bestel-Corre G, Dumas-Gaudot E, Berta G, Gianinazzi-Pearson V, Gianinazzi S.
PMID: 33873415
New Phytol. 2003 Mar;157(3):555-567. doi: 10.1046/j.1469-8137.2003.00682.x.

•   Arbuscular mycorrhiza (AM) can increase plant tolerance to heavy metals. A targeted proteomic approach was used to determine the putative identity of some of the proteins induced/modulated by cadmium (Cd) and to analyse the impact of the mycorrhizal...

HPG-Dependent Peri-Pubertal Regulation of Adult Neurogenesis in Mice.

Frontiers in neuroanatomy

Trova S, Bovetti S, Pellegrino G, Bonzano S, Giacobini P, Peretto P.
PMID: 33328903
Front Neuroanat. 2020 Nov 27;14:584493. doi: 10.3389/fnana.2020.584493. eCollection 2020.

Adult neurogenesis, a striking form of neural plasticity, is involved in the modulation of social stimuli driving reproduction. Previous studies on adult neurogenesis have shown that this process is significantly modulated around puberty in female mice. Puberty is a...

Showing 181 to 190 of 190 entries