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Showing 157 to 168 of 168 entries
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Soybean Yellow Stripe-like 7 is a symbiosome membrane peptide transporter important for nitrogen fixation.

Plant physiology

Gavrin A, Loughlin PC, Brear E, Griffith OW, Bedon F, Suter Grotemeyer M, Escudero V, Reguera M, Qu Y, Mohd-Noor SN, Chen C, Osorio MB, Rentsch D, González-Guerrero M, Day DA, Smith PMC.
PMID: 33619553
Plant Physiol. 2021 May 27;186(1):581-598. doi: 10.1093/plphys/kiab044.

Legumes form a symbiosis with rhizobia that convert atmospheric nitrogen (N2) to ammonia and provide it to the plant in return for a carbon and nutrient supply. Nodules, developed as part of the symbiosis, harbor rhizobia that are enclosed...

Insufficient Stability of Clavulanic Acid in Widely Used Child-Appropriate Formulations.

Antibiotics (Basel, Switzerland)

Mack I, Sharland M, Brussee JM, Rehm S, Rentsch K, Bielicki J.
PMID: 33672363
Antibiotics (Basel). 2021 Feb 23;10(2). doi: 10.3390/antibiotics10020225.

Amoxicillin-clavulanic acid (AMC) belongs to the WHO Essential Medicines List for children, but for optimal antimicrobial effectiveness, reconstituted dry powder suspensions need to be stored in a refrigerated environment. Many patients in low- and middle-income countries who are sold...

Polypharmacy-associated risk of hospitalisation among people ageing with and without HIV: an observational study.

The Lancet. Healthy longevity

Justice AC, Gordon KS, Romero J, Edelman EJ, Garcia BJ, Jones P, Khoo S, Lo Re V, Rentsch CT, Tate JP, Tseng A, Womack J, Jacobson D.
PMID: 34870254
Lancet Healthy Longev. 2021 Oct;2(10):e639-e650. doi: 10.1016/S2666-7568(21)00206-3. Epub 2021 Sep 29.

BACKGROUND: Polypharmacy, defined as use of five or more medications concurrently, is associated with adverse health outcomes and people ageing with HIV might be at greater risk than similar uninfected individuals. We aimed to determine whether known pairwise drug...

Direct Comparison of Clinical Characteristics, Outcomes, and Risk Prediction in Patients with COVID-19 and Controls-A Prospective Cohort Study.

Journal of clinical medicine

Lampart M, Rüegg M, Jauslin AS, Simon NR, Zellweger N, Eken C, Tschudin-Sutter S, Bassetti S, Rentsch KM, Siegemund M, Bingisser R, Nickel CH, Osswald S, Kuster GM, Twerenbold R.
PMID: 34204453
J Clin Med. 2021 Jun 17;10(12). doi: 10.3390/jcm10122672.

Most studies investigating early risk predictors in coronavirus disease 19 (COVID-19) lacked comparison with controls. We aimed to assess and directly compare outcomes and risk predictors at time of emergency department (ED) presentation in COVID-19 and controls. Consecutive patients...

Corrigendum to 'In vitro measurement of the chemical changes occurring within β-tricalcium phosphate bone graft substitutes' Acta Biomaterialia 2020, ISSUE/VOLUME 102, 440-457.

Acta biomaterialia

Maazouz Y, Rentsch I, Bin L, Santoni BLG, Doebelin N, Bohner M.
PMID: 34334348
Acta Biomater. 2021 Oct 15;134:818. doi: 10.1016/j.actbio.2021.07.025. Epub 2021 Jul 29.

No abstract available.

A community-targeted implementation of self-management for people with epilepsy and a history of negative health events (SMART): A research and community partnership to reduce epilepsy burden.

Epilepsy & behavior : E&B

Kottapalli I, Needham K, Colón-Zimmermann K, Richter N, Schrag K, Ryan ER, Storer N, Sarna K, Briggs FBS, Rentsch J, Sajatovic M.
PMID: 34920349
Epilepsy Behav. 2021 Dec 14;126:108440. doi: 10.1016/j.yebeh.2021.108440. Epub 2021 Dec 14.

AIMS: Self-management for people with epilepsy and a history of negative health events (SMART) is a behavioral intervention that has been demonstrated to reduce epilepsy-related complications and improve physical and mental health functioning among people with epilepsy (PWE) [1]....

Protease inhibitor-based direct-acting antivirals are associated with increased risk of aminotransferase elevations but not hepatic dysfunction or decompensation.

Journal of hepatology

Torgersen J, Newcomb CW, Carbonari DM, Rentsch CT, Park LS, Mezochow A, Mehta RL, Buchwalder L, Tate JP, Bräu N, Bhattacharya D, Lim JK, Taddei TH, Justice AC, Lo Re V.
PMID: 34333102
J Hepatol. 2021 Dec;75(6):1312-1322. doi: 10.1016/j.jhep.2021.07.021. Epub 2021 Jul 29.

BACKGROUND & AIMS: Cases of acute liver injury (ALI) have been reported among chronic HCV-infected patients receiving protease inhibitor (PI)-based direct-acting antiviral (DAA) regimens, but no analyses have compared the risk of ALI in patients receiving PI- vs. non-PI-based...

Effect of pre-exposure use of hydroxychloroquine on COVID-19 mortality: a population-based cohort study in patients with rheumatoid arthritis or systemic lupus erythematosus using the OpenSAFELY platform.

The Lancet. Rheumatology

Rentsch CT, DeVito NJ, MacKenna B, Morton CE, Bhaskaran K, Brown JP, Schultze A, Hulme WJ, Croker R, Walker AJ, Williamson EJ, Bates C, Bacon S, Mehrkar A, Curtis HJ, Evans D, Wing K, Inglesby P, Mathur R, Drysdale H, Wong AYS, McDonald HI, Cockburn J, Forbes H, Parry J, Hester F, Harper S, Smeeth L, Douglas IJ, Dixon WG, Evans SJW, Tomlinson L, Goldacre B.
PMID: 33349815
Lancet Rheumatol. 2021 Jan;3(1):e19-e27. doi: 10.1016/S2665-9913(20)30378-7. Epub 2020 Nov 05.

BACKGROUND: Hydroxychloroquine has been shown to inhibit entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into epithelial cells in vitro, but clinical studies found no evidence of reduced mortality when treating patients with COVID-19. We aimed to evaluate...

Early initiation of prophylactic anticoagulation for prevention of COVID-19 mortality: a nationwide cohort study of hospitalized patients in the United States.

medRxiv : the preprint server for health sciences

Rentsch CT, Beckman JA, Tomlinson L, Gellad WF, Alcorn C, Kidwai-Khan F, Skanderson M, Brittain E, King JT, Ho YL, Eden S, Kundu S, Lann MF, Greevy RA, Ho PM, Heidenreich PA, Jacobson DA, Douglas IJ, Tate JP, Evans SJ, Atkins D, Justice AC, Freiberg MS.
PMID: 33330896
medRxiv. 2020 Dec 11; doi: 10.1101/2020.12.09.20246579.

IMPORTANCE: Deaths among patients with coronavirus disease 2019 (COVID-19) are partially attributed to venous thromboembolism and arterial thromboses. Anticoagulants prevent thrombosis formation, possess anti-inflammatory and anti-viral properties, and may be particularly effective for treating patients with COVID-19.OBJECTIVE: To evaluate...

Clinical coding of long COVID in English primary care: a federated analysis of 58 million patient records .

The British journal of general practice : the journal of the Royal College of General Practitioners

Walker AJ, MacKenna B, Inglesby P, Tomlinson L, Rentsch CT, Curtis HJ, Morton CE, Morley J, Mehrkar A, Bacon S, Hickman G, Bates C, Croker R, Evans D, Ward T, Cockburn J, Davy S, Bhaskaran K, Schultze A, Williamson EJ, Hulme WJ, McDonald HI, Mathur R, Eggo RM, Wing K, Wong AY, Forbes H, Tazare J, Parry J, Hester F, Harper S, O'Hanlon S, Eavis A, Jarvis R, Avramov D, Griffiths P, Fowles A, Parkes N, Douglas IJ, Evans SJ.
PMID: 34340970
Br J Gen Pract. 2021 Oct 28;71(712):e806-e814. doi: 10.3399/BJGP.2021.0301. Print 2021 Nov.

BACKGROUND: Long COVID describes new or persistent symptoms at least 4 weeks after onset of acute COVID-19. Clinical codes to describe this phenomenon were recently created.AIM: To describe the use of long-COVID codes, and variation of use by general...

The Al Doping Effect on Epitaxial (In,Mn)As Dilute Magnetic Semiconductors Prepared by Ion Implantation and Pulsed Laser Melting.

Materials (Basel, Switzerland)

Yuan Y, Xie Y, Yuan N, Wang M, Heller R, Kentsch U, Zhai T, Wang X.
PMID: 34361332
Materials (Basel). 2021 Jul 25;14(15). doi: 10.3390/ma14154138.

One of the most attractive characteristics of diluted ferromagnetic semiconductors is the possibility to modulate their electronic and ferromagnetic properties, coupled by itinerant holes through various means. A prominent example is the modification of Curie temperature and magnetic anisotropy...

OpenSAFELY NHS Service Restoration Observatory 1: primary care clinical activity in England during the first wave of COVID-19.

The British journal of general practice : the journal of the Royal College of General Practitioners

Curtis HJ, MacKenna B, Croker R, Inglesby P, Walker AJ, Morley J, Mehrkar A, Morton CE, Bacon S, Hickman G, Bates C, Evans D, Ward T, Cockburn J, Davy S, Bhaskaran K, Schultze A, Rentsch CT, Williamson EJ, Hulme WJ, McDonald HI, Tomlinson L, Mathur R, Drysdale H, Eggo RM, Wing K, Wong AY, Forbes H, Parry J, Hester F, Harper S, Evans SJ, Douglas IJ, Smeeth L, Goldacre B.
PMID: 34750105
Br J Gen Pract. 2021 Dec 31;72(714):e63-e74. doi: 10.3399/BJGP.2021.0380. Print 2022 Jan.

BACKGROUND: The COVID-19 pandemic has disrupted healthcare activity. The NHS stopped non-urgent work in March 2020, later recommending services be restored to near-normal levels before winter where possible.AIM: To describe the volume and variation of coded clinical activity in...

Showing 157 to 168 of 168 entries