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Showing 13 to 24 of 241 entries
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Terahertz spectroscopy of 2,4,6-trinitrotoluene molecular solids from first principles.

Beilstein journal of organic chemistry

Azuri I, Hirsch A, Reilly AM, Tkatchenko A, Kendler S, Hod O, Kronik L.
PMID: 29507643
Beilstein J Org Chem. 2018 Feb 09;14:381-388. doi: 10.3762/bjoc.14.26. eCollection 2018.

We present a computational analysis of the terahertz spectra of the monoclinic and the orthorhombic polymorphs of 2,4,6-trinitrotoluene. Very good agreement with experimental data is found when using density functional theory that includes Tkatchenko-Scheffler pair-wise dispersion interactions. Furthermore, we...

A high-fat diet catalyzes progression to hyperglycemia in mice with selective impairment of insulin action in Glut4-expressing tissues.

The Journal of biological chemistry

Reilly AM, Yan S, Huang M, Abhyankar SD, Conley JM, Bone RN, Stull ND, Horan DJ, Roh HC, Robling AG, Ericsson AC, Dong XC, Evans-Molina C, Ren H.
PMID: 34801552
J Biol Chem. 2021 Nov 18;298(1):101431. doi: 10.1016/j.jbc.2021.101431. Epub 2021 Nov 18.

Insulin resistance impairs postprandial glucose uptake through glucose transporter type 4 (GLUT4) and is the primary defect preceding type 2 diabetes. We previously generated an insulin-resistant mouse model with human GLUT4 promoter-driven insulin receptor knockout (GIRKO) in the muscle,...

Recurrent Respiratory Papillomatosis With Complete Response to Systemic Bevacizumab Therapy.

Ear, nose, & throat journal

Gorelik D, Frantz A, Dome JS, Reilly BK.
PMID: 34392730
Ear Nose Throat J. 2021 Aug 15;1455613211040578. doi: 10.1177/01455613211040578. Epub 2021 Aug 15.

Recurrent respiratory papillomatosis is a condition caused by human papilloma virus, usually sub types 6 and 11. Papillomas are benign neoplasms that are most commonly found on the larynx and can be often associated with significant airway involvement. Frequency...

Brentuximab vedotin in combination with chemotherapy for pediatric patients with ALK+ ALCL: results of COG trial ANHL12P1.

Blood

Lowe EJ, Reilly AF, Lim MS, Gross TG, Saguilig L, Barkauskas DA, Wu R, Alexander S, Bollard CM.
PMID: 33684925
Blood. 2021 Jul 01;137(26):3595-3603. doi: 10.1182/blood.2020009806.

Approximately 30% of pediatric patients with anaplastic large cell lymphoma (ALCL) relapse. Although brentuximab vedotin has demonstrated excellent activity in ALCL, it has not been used for newly diagnosed patients. Children's Oncology Group (COG) trial ANHL12P1 determined the toxicity...

Inter-rater and Intra-rater Reliability in the Radiographic Diagnosis of Growth Arrest in Paediatric Physeal Fractures.

Indian journal of orthopaedics

Banting N, Schaeffer EK, Bone J, Habib E, Hooper N, Reilly CW, Cooper A, Mulpuri K.
PMID: 34306559
Indian J Orthop. 2021 May 17;55:445-451. doi: 10.1007/s43465-020-00327-9. eCollection 2021 Jul.

BACKGROUND: Fractures through the physis account for 18-30% of paediatric fractures and can lead to growth arrest in 5-10% of these cases. Long-term radiographic follow-up is usually necessary to monitor for signs of growth arrest at the affected physis....

Commentary: Symptomatic Epidural Hematoma After Elective Cervical Spine Surgery: Incidence, Timing, Risk Factors, and Associated Complications.

Operative neurosurgery (Hagerstown, Md.)

Kidwell RL, Tan LA.
PMID: 35007237
Oper Neurosurg (Hagerstown). 2021 Dec 22; doi: 10.1227/ONS.0000000000000070. Epub 2021 Dec 22.

No abstract available.

Partnerships to improve social determinants of health, health equity, and health outcomes: An SNRS whitepaper.

Research in nursing & health

Ahn H, Butts B, Cottrell DB, Kesey J, McNeill CC, Mumba MN, O'Brien T, Reifsnider E, Reilly CM.
PMID: 34800040
Res Nurs Health. 2021 Nov 20; doi: 10.1002/nur.22198. Epub 2021 Nov 20.

No abstract available.

Remdesivir and GS-441524 Extraction by Ex Vivo Extracorporeal Life Support Circuits.

ASAIO journal (American Society for Artificial Internal Organs : 1992)

Imburgia CE, Rower JE, Green DJ, Mcknite AM, Kelley WE, Reilly CA, Watt KM.
PMID: 34799526
ASAIO J. 2021 Nov 17; doi: 10.1097/MAT.0000000000001616. Epub 2021 Nov 17.

Patients with severe, COVID-related multi-organ failure often require extracorporeal life support (ECLS) such as extracorporeal membrane oxygenation (ECMO) or continuous renal replacement therapy (CRRT). An ECLS can alter drug exposure via multiple mechanisms. Remdesivir (RDV) and its active metabolite...

A high-fat diet catalyzes progression to hyperglycemia in mice with selective impairment of insulin action in Glut4-expressing tissues.

The Journal of biological chemistry

Reilly AM, Yan S, Huang M, Abhyankar SD, Conley JM, Bone RN, Stull ND, Horan DJ, Roh HC, Robling AG, Ericsson AC, Dong XC, Evans-Molina C, Ren H.
PMID: 34801552
J Biol Chem. 2021 Nov 18;298(1):101431. doi: 10.1016/j.jbc.2021.101431. Epub 2021 Nov 18.

Insulin resistance impairs postprandial glucose uptake through glucose transporter type 4 (GLUT4) and is the primary defect preceding type 2 diabetes. We previously generated an insulin-resistant mouse model with human GLUT4 promoter-driven insulin receptor knockout (GIRKO) in the muscle,...

A trial of a six-month sugar-sweetened beverage intervention in secondary schools from a socio-economically disadvantaged region in Australia.

Australian and New Zealand journal of public health

Ooi JY, Wolfenden L, Yoong SL, Janssen LM, Reilly K, Nathan N, Sutherland R.
PMID: 34761854
Aust N Z J Public Health. 2021 Dec;45(6):599-607. doi: 10.1111/1753-6405.13159. Epub 2021 Nov 11.

OBJECTIVE: This study assessed the effectiveness of a school-based intervention in reducing adolescents' sugar-sweetened beverage (SSB) consumption and percentage of energy from SSBs. Secondary outcomes were SSB consumption within school, average daily energy intake, and body mass index z-scores.METHODS:...

Synthetic DNA spike-ins (SDSIs) enable sample tracking and detection of inter-sample contamination in SARS-CoV-2 sequencing workflows.

Nature microbiology

Lagerborg KA, Normandin E, Bauer MR, Adams G, Figueroa K, Loreth C, Gladden-Young A, Shaw BM, Pearlman LR, Berenzy D, Dewey HB, Kales S, Dobbins ST, Shenoy ES, Hooper D, Pierce VM, Zachary KC, Park DJ, MacInnis BL, Tewhey R, Lemieux JE, Sabeti PC, Reilly SK, Siddle KJ.
PMID: 34907347
Nat Microbiol. 2022 Jan;7(1):108-119. doi: 10.1038/s41564-021-01019-2. Epub 2021 Dec 14.

The global spread and continued evolution of SARS-CoV-2 has driven an unprecedented surge in viral genomic surveillance. Amplicon-based sequencing methods provide a sensitive, low-cost and rapid approach but suffer a high potential for contamination, which can undermine laboratory processes...

Efficacy and safety of as-needed albuterol/budesonide versus albuterol in adults and children aged ≥4 years with moderate-to-severe asthma: rationale and design of the randomised, double-blind, active-controlled MANDALA study.

BMJ open respiratory research

Chipps BE, Albers FC, Reilly L, Johnsson E, Cappelletti C, Papi A.
PMID: 34887317
BMJ Open Respir Res. 2021 Dec;8(1). doi: 10.1136/bmjresp-2021-001077.

INTRODUCTION: Uncontrolled asthma is associated with substantial morbidity. While fast-acting bronchodilators provide quick relief from asthma symptoms, their use as rescue fails to address the underlying inflammation. Combining a short-acting betaMETHODS AND ANALYSIS: The Phase 3 MANDALA study was...

Showing 13 to 24 of 241 entries