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Showing 229 to 234 of 234 entries
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PI3K-driven HER2 expression is a potential therapeutic target in colorectal cancer stem cells.

Gut

Mangiapane LR, Nicotra A, Turdo A, Gaggianesi M, Bianca P, Di Franco S, Sardina DS, Veschi V, Signore M, Beyes S, Fagnocchi L, Fiori ME, Bongiorno MR, Lo Iacono M, Pillitteri I, Ganduscio G, Gulotta G, Medema JP, Zippo A, Todaro M, De Maria R, Stassi G.
PMID: 33436496
Gut. 2022 Jan;71(1):119-128. doi: 10.1136/gutjnl-2020-323553. Epub 2021 Jan 12.

OBJECTIVE: Cancer stem cells are responsible for tumour spreading and relapse. Human epidermal growth factor receptor 2 (HER2) expression is a negative prognostic factor in colorectal cancer (CRC) and a potential target in tumours carrying the gene amplification. Our...

Patient-Reported Outcomes in Cardiovascular Trials.

The Canadian journal of cardiology

Masterson Creber R, Spadaccio C, Dimagli A, Myers A, Taylor B, Fremes S.
PMID: 33974992
Can J Cardiol. 2021 Sep;37(9):1340-1352. doi: 10.1016/j.cjca.2021.04.006. Epub 2021 May 08.

Patient-reported outcomes (PROs) are reports of a person's health status that provide a global perspective of patient well-being. PROs can be classified into 4 primary domains: global, mental, physical, and social health. In this descriptive review, we focus on...

Reduced order methods for parametric optimal flow control in coronary bypass grafts, toward patient-specific data assimilation.

International journal for numerical methods in biomedical engineering

Zainib Z, Ballarin F, Fremes S, Triverio P, Jiménez-Juan L, Rozza G.
PMID: 32458572
Int J Numer Method Biomed Eng. 2021 Dec;37(12):e3367. doi: 10.1002/cnm.3367. Epub 2020 Jul 08.

Coronary artery bypass grafts (CABG) surgery is an invasive procedure performed to circumvent partial or complete blood flow blockage in coronary artery disease. In this work, we apply a numerical optimal flow control model to patient-specific geometries of CABG,...

Expression of programmed death ligand-1 (PD-L1) in metastatic and postchemotherapy viable testicular germ cell tumors.

Urologic oncology

Al-Hogbani M, Duguay J, Wagner DC, Haferkamp A, Joubert P, Frees S, Rendon R, Power N, Périgny M, Toren P.
PMID: 33685799
Urol Oncol. 2021 May;39(5):303.e1-303.e8. doi: 10.1016/j.urolonc.2021.02.014. Epub 2021 Mar 05.

INTRODUCTION: Chemotherapy for testicular germ cell tumors (GCT) is highly effective, with few patients who do not respond. Clinical studies to evaluated novel treatments are challenging given the rarity of these patients. Therefore, we sought to evaluate PD-L1 staining...

A familial case of .

SAGE open medical case reports

Heiman P, Drewes S, Ghaloul-Gonzalez L.
PMID: 33796307
SAGE Open Med Case Rep. 2021 Feb 01;9:2050313X21990982. doi: 10.1177/2050313X21990982. eCollection 2021.

Variants in CAMK2-associated genes have recently been implicated in neurodevelopmental disorders and intellectual disability. The clinical manifestations reported in patients with mutations in these genes include intellectual disability (ranging from mild to severe), global developmental delay, seizures, delayed speech,...

CS10K teachers by 2017? Try CS1K+ students NOW! Coping with the largest CS1 courses in history.

Garcia DD, Campbell J, DeNero J, Dorf ML, Reges S.
UIID-AD: 4182
2016;396-397. doi: 10.1145/2839509.2844660.

"Be careful what you wish for, you just might get it."- Proverb In 2005, computing education was experiencing a crisis. Enrollments had "fallen to such an extent that some academic computing programs were facing significant reductions in staffing levels...

Showing 229 to 234 of 234 entries