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Showing 73 to 77 of 77 entries
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'It is good to have a target in mind': qualitative views of patients and parents informing a treat to target clinical trial in juvenile-onset systemic lupus erythematosus.

Rheumatology (Oxford, England)

Smith EMD, Gorst SL, Al-Abadi E, Hawley DP, Leone V, Pilkington C, Ramanan AV, Rangaraj S, Sridhar A, Beresford MW, Young B.
PMID: 33629109
Rheumatology (Oxford). 2021 Dec 01;60(12):5630-5641. doi: 10.1093/rheumatology/keab173.

OBJECTIVE: We sought to explore patient and parental views on treatment targets, outcome measures and study designs being considered for a future JSLE treat-to-target (T2T) study.METHODS: We conducted topic-guided, semistructured interviews with JSLE patients and parents and analysed the...

Real-World Experience in Toxicity with Bevacizumab in Indian Cancer Patients.

South Asian journal of cancer

Patil PP, Rangaraju RR, Abbas W, Garg S.
PMID: 34568227
South Asian J Cancer. 2021 Apr;10(2):131-134. doi: 10.1055/s-0041-1729445. Epub 2021 Sep 04.

No abstract available.

Phase IIa Global Study Evaluating Rituximab for the Treatment of Pediatric Patients With Granulomatosis With Polyangiitis or Microscopic Polyangiitis.

Arthritis & rheumatology (Hoboken, N.J.)

Brogan P, Yeung RSM, Cleary G, Rangaraj S, Kasapcopur O, Hersh AO, Li S, Paripovic D, Schikler K, Zeft A, Bracaglia C, Eleftheriou D, Pordeli P, Melega S, Jamois C, Gaudreault J, Michalska M, Brunetta P, Cooper JC, Lehane PB.
PMID: 34164952
Arthritis Rheumatol. 2021 Jun 23; doi: 10.1002/art.41901. Epub 2021 Jun 23.

OBJECTIVE: To assess the safety, tolerability, pharmacokinetics, and efficacy of rituximab (RTX) in pediatric patients with granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA).METHODS: The Pediatric Polyangiitis Rituximab Study was a phase IIa, international, open-label, single-arm study. During the...

Implementation research to accelerate scale-up of national screen and treat strategies towards the elimination of cervical cancer.

Preventive medicine

Broutet N, Jeronimo J, Kumar S, Almonte M, Murillo R, Huy NVQ, Denny L, Kapambwe S, Bhatla N, Sebitloane M, Zhao F, Gravitt P, Adsul P, Rangaraj A, Dalal S, Newman M, Chowdhury R, Church K, Nakisige C, Diop M, Parham G, Thomson KA, Basu P, Steyn P.
PMID: 34896155
Prev Med. 2021 Dec 08;155:106906. doi: 10.1016/j.ypmed.2021.106906. Epub 2021 Dec 08.

BACKGROUND: Cervical cancer is a significant public health problem, with 570,000 new cases and 300,000 deaths of women per year globally, mostly in low- and middle-income countries. In 2018 the WHO Director General made a call to action for...

Y chromosomal noncoding RNAs regulate autosomal gene expression via piRNAs in mouse testis.

BMC biology

Reddy HM, Bhattacharya R, Tiwari S, Mishra K, Annapurna P, Jehan Z, Praveena NM, Alex JL, Dhople VM, Singh L, Sivaramakrishnan M, Chaturvedi A, Rangaraj N, Shiju TM, Sreedevi B, Kumar S, Dereddi RR, Rayabandla SM, Jesudasan RA.
PMID: 34503492
BMC Biol. 2021 Sep 09;19(1):198. doi: 10.1186/s12915-021-01125-x.

BACKGROUND: Deciphering the functions of Y chromosome in mammals has been slow owing to the presence of repeats. Some of these repeats transcribe coding RNAs, the roles of which have been studied. Functions of the noncoding transcripts from Y...

Showing 73 to 77 of 77 entries