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Showing 13 to 24 of 100 entries
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HB-EGF-EGFR Signaling in Bone Marrow Endothelial Cells Mediates Angiogenesis Associated with Multiple Myeloma.

Cancers

Rao L, Giannico D, Leone P, Solimando AG, Maiorano E, Caporusso C, Duda L, Tamma R, Mallamaci R, Susca N, Buonavoglia A, Da Vià MC, Ribatti D, De Re V, Vacca A, Racanelli V.
PMID: 31936715
Cancers (Basel). 2020 Jan 10;12(1). doi: 10.3390/cancers12010173.

Epidermal growth factor receptor (EGFR) and its ligand heparin-binding EGF-like growth factor (HB-EGF) sustain endothelial cell proliferation and angiogenesis in solid tumors, but little is known about the role of HB-EGF-EGFR signaling in bone marrow angiogenesis and multiple myeloma...

Exploiting systems biology to investigate the gene modules and drugs in ovarian cancer: A hypothesis based on the weighted gene co-expression network analysis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Nomiri S, Karami H, Baradaran B, Javadrashid D, Derakhshani A, Nourbakhsh NS, Shadbad MA, Solimando AG, Tabrizi NJ, Brunetti O, Nasseri S, Racanelli V, Safarpour H, Silvestris N.
PMID: 34922114
Biomed Pharmacother. 2021 Dec 15;146:112537. doi: 10.1016/j.biopha.2021.112537. Epub 2021 Dec 15.

BACKGROUND: Ovarian cancer (OC) is one of the worrisome gynecological cancers worldwide. Given its considerable mortality rate, it is necessary to investigate its oncogenesis.METHODS: In this study, we used systems biology approaches to describe the key gene modules, hub...

Anti-COVID-19 Vaccination in Patients with Autoimmune-Autoinflammatory Disorders and Primary/Secondary Immunodeficiencies: The Position of the Task Force on Behalf of the Italian Immunological Societies.

Biomedicines

D'Amelio R, Asero R, Cassatella MA, Laganà B, Lunardi C, Migliorini P, Nisini R, Parronchi P, Quinti I, Racanelli V, Senna G, Vacca A, Maggi E.
PMID: 34572349
Biomedicines. 2021 Sep 04;9(9). doi: 10.3390/biomedicines9091163.

The Coronavirus disease 2019 (COVID-19) pandemic has represented an unprecedented challenge for humankind from health, economic, and social viewpoints. In February 2020, Italy was the first western country to be deeply hit by the pandemic and suffered the highest...

Antibiotics or No Antibiotics, That Is the Question: An Update on Efficient and Effective Use of Antibiotics in Dental Practice.

Antibiotics (Basel, Switzerland)

Buonavoglia A, Leone P, Solimando AG, Fasano R, Malerba E, Prete M, Corrente M, Prati C, Vacca A, Racanelli V.
PMID: 34065113
Antibiotics (Basel). 2021 May 09;10(5). doi: 10.3390/antibiotics10050550.

The antimicrobial resistance (AMR) phenomenon is an emerging global problem and is induced by overuse and misuse of antibiotics in medical practice. In total, 10% of antibiotic prescriptions are from dentists, usually to manage oro-dental pains and avoid postsurgical...

CT pulmonary angiography appropriateness in a single emergency department: does the use of revised Geneva score matter?.

La Radiologia medica

Mirabile A, Lucarelli NM, Sollazzo EP, Stabile Ianora AA, Sardaro A, Mirabile G, Lorusso F, Racanelli V, Maggialetti N, Scardapane A.
PMID: 34518985
Radiol Med. 2021 Dec;126(12):1544-1552. doi: 10.1007/s11547-021-01416-x. Epub 2021 Sep 13.

PURPOSE: To assess the percentage of computed tomography pulmonary angiography (CTPA) procedures that could have been avoided by methodical application of the Revised Geneva Score (RGS) coupled with age-adjusted D-dimer cut-offs rather than only clinical judgment in Emergency Department...

The Evolving Role of Immune Checkpoint Inhibitors in Hepatocellular Carcinoma Treatment.

Vaccines

Leone P, Solimando AG, Fasano R, Argentiero A, Malerba E, Buonavoglia A, Lupo LG, De Re V, Silvestris N, Racanelli V.
PMID: 34065489
Vaccines (Basel). 2021 May 20;9(5). doi: 10.3390/vaccines9050532.

Hepatocellular carcinoma (HCC) is one of most common cancers and the fourth leading cause of death worldwide. Commonly, HCC development occurs in a liver that is severely compromised by chronic injury or inflammation. Liver transplantation, hepatic resection, radiofrequency ablation...

CRMP4-mediated fornix development involves Semaphorin-3E signaling pathway.

eLife

Boulan B, Ravanello C, Peyrel A, Bosc C, Delphin C, Appaix F, Denarier E, Kraut A, Jacquier-Sarlin M, Fournier A, Andrieux A, Gory-Fauré S, Deloulme JC.
PMID: 34860155
Elife. 2021 Dec 03;10. doi: 10.7554/eLife.70361.

Neurodevelopmental axonal pathfinding plays a central role in correct brain wiring and subsequent cognitive abilities. Within the growth cone, various intracellular effectors transduce axonal guidance signals by remodeling the cytoskeleton. Semaphorin-3E (Sema3E) is a guidance cue implicated in development...

CT pulmonary angiography appropriateness in a single emergency department: does the use of revised Geneva score matter?.

La Radiologia medica

Mirabile A, Lucarelli NM, Sollazzo EP, Stabile Ianora AA, Sardaro A, Mirabile G, Lorusso F, Racanelli V, Maggialetti N, Scardapane A.
PMID: 34518985
Radiol Med. 2021 Dec;126(12):1544-1552. doi: 10.1007/s11547-021-01416-x. Epub 2021 Sep 13.

PURPOSE: To assess the percentage of computed tomography pulmonary angiography (CTPA) procedures that could have been avoided by methodical application of the Revised Geneva Score (RGS) coupled with age-adjusted D-dimer cut-offs rather than only clinical judgment in Emergency Department...

Exploiting systems biology to investigate the gene modules and drugs in ovarian cancer: A hypothesis based on the weighted gene co-expression network analysis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Nomiri S, Karami H, Baradaran B, Javadrashid D, Derakhshani A, Nourbakhsh NS, Shadbad MA, Solimando AG, Tabrizi NJ, Brunetti O, Nasseri S, Racanelli V, Safarpour H, Silvestris N.
PMID: 34922114
Biomed Pharmacother. 2021 Dec 16;146:112537. doi: 10.1016/j.biopha.2021.112537. Epub 2021 Dec 16.

BACKGROUND: Ovarian cancer (OC) is one of the worrisome gynecological cancers worldwide. Given its considerable mortality rate, it is necessary to investigate its oncogenesis.METHODS: In this study, we used systems biology approaches to describe the key gene modules, hub...

Anti-angiogenesis and Immunotherapy: Novel Paradigms to Envision Tailored Approaches in Renal Cell-Carcinoma.

Journal of clinical medicine

Argentiero A, Solimando AG, Krebs M, Leone P, Susca N, Brunetti O, Racanelli V, Vacca A, Silvestris N.
PMID: 32456352
J Clin Med. 2020 May 24;9(5). doi: 10.3390/jcm9051594.

Although decision making strategy based on clinico-histopathological criteria is well established, renal cell carcinoma (RCC) represents a spectrum of biological ecosystems characterized by distinct genetic and molecular alterations, diverse clinical courses and potential specific therapeutic vulnerabilities. Given the plethora...

CRMP4-mediated fornix development involves semaphorin-3E signaling pathway.

eLife

Boulan B, Ravanello C, Peyrel A, Bosc C, Delphin C, Appaix F, Denarier E, Kraut A, Jacquier-Sarlin M, Fournier A, Andrieux A, Gory-Fauré S, Deloulme JC.
PMID: 34860155
Elife. 2021 Dec 03;10. doi: 10.7554/eLife.70361. Epub 2021 Dec 03.

Neurodevelopmental axonal pathfinding plays a central role in correct brain wiring and subsequent cognitive abilities. Within the growth cone, various intracellular effectors transduce axonal guidance signals by remodeling the cytoskeleton. Semaphorin-3E (Sema3E) is a guidance cue implicated in development...

Early postnatal overnutrition impairs VO.

Journal of developmental origins of health and disease

Almeida DL, Fabricio GS, Tófolo LP, Ribeiro TA, Matiusso CCI, Ribeiro MVG, Oliveira Ferreira AR, Pavanello A, Malta A, Palma-Rigo K, de Freitas Mathias PC.
PMID: 34284843
J Dev Orig Health Dis. 2021 Jul 21;1-5. doi: 10.1017/S2040174421000428. Epub 2021 Jul 21.

Exercise counteracts obesity effects, but information on how early-life obesity may affect long-term adaptation to exercise is lacking. This study investigates the impact of early-life postnatal overfeeding (PO) on animals' adaptation to exercise. Only male Wistar rats were used....

Showing 13 to 24 of 100 entries