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Showing 25 to 36 of 172 entries
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The effects of isoflavone supplementation plus combined exercise on salivary markers of oxidative stress in postmenopausal women.

Journal of clinical biochemistry and nutrition

Amaral AL, Mendonça AM, Giolo JS, Costa JG, Mariano IM, de Souza TCF, Batista JP, Rodrigues ML, de Souza AV, Caixeta DC, Peixoto LG, de Oliveira EP, Espindola FS, Puga GM.
PMID: 32001955
J Clin Biochem Nutr. 2020 Jan;66(1):43-48. doi: 10.3164/jcbn.19-44. Epub 2019 Oct 31.

This study tested the effect of isoflavone supplementation in addition to combined exercise training in salivary oxidative stress markers in non-obese postmenopausal women. Thirty-two postmenopausal women without hormone therapy were randomly assigned to exercise + placebo (

(Meta-)stability and Core-Shell Dynamics of Gold Nanoclusters at Finite Temperature.

The journal of physical chemistry letters

Guedes-Sobrinho D, Wang W, Hamilton IP, Da Silva JLF, Ghiringhelli LM.
PMID: 30681851
J Phys Chem Lett. 2019 Feb 07;10(3):685-692. doi: 10.1021/acs.jpclett.8b03397. Epub 2019 Jan 30.

Gold nanoclusters have been the focus of numerous computational studies, but an atomistic understanding of their structural and dynamical properties at finite temperature is far from satisfactory. To address this deficiency, we investigate gold nanoclusters via ab initio molecular...

Integrative diagnosis, biological observations, and histopathology of the fig cyst nematode .

ZooKeys

Fanelli E, Vovlas A, Santoro S, Troccoli A, Giuseppe Lucarelli, Trisciuzzi N, Luca F.
PMID: 30814900
Zookeys. 2019 Feb 12;(824):1-19. doi: 10.3897/zookeys.824.26820. eCollection 2019.

Morpho-biological notes and histopathology, based on LM and SEM observations, of the fig cyst nematode

Viewpoint: Atomic-Scale Design Protocols toward Energy, Electronic, Catalysis, and Sensing Applications.

Inorganic chemistry

Belviso F, Claerbout VEP, Comas-Vives A, Dalal NS, Fan FR, Filippetti A, Fiorentini V, Foppa L, Franchini C, Geisler B, Ghiringhelli LM, Groß A, Hu S, Íñiguez J, Kauwe SK, Musfeldt JL, Nicolini P, Pentcheva R, Polcar T, Ren W, Ricci F, Ricci F, Sen HS, Skelton JM, Sparks TD, Stroppa A, Urru A, Vandichel M, Vavassori P, Wu H, Yang K, Zhao HJ, Puggioni D, Cortese R, Cammarata A.
PMID: 31668070
Inorg Chem. 2019 Nov 18;58(22):14939-14980. doi: 10.1021/acs.inorgchem.9b01785. Epub 2019 Oct 31.

Nanostructured materials are essential building blocks for the fabrication of new devices for energy harvesting/storage, sensing, catalysis, magnetic, and optoelectronic applications. However, because of the increase of technological needs, it is essential to identify new functional materials and improve...

Feasibility of Using Short Message Service and In-Depth Interviews to Collect Data on Contraceptive Use Among Young, Unmarried, Sexually Active Men in Moshi, Tanzania, and Addis Ababa, Ethiopia: Mixed Methods Study With a Longitudinal Follow-Up.

JMIR formative research

Pima FM, Oshosen M, Ngowi KM, Habte BM, Maro E, Teffera BE, Kisigo G, Swai IU, Msangi SS, Ermias A, Mmbaga BT, Both R, Sumari-de Boer M.
PMID: 31244476
JMIR Form Res. 2019 Jun 26;3(2):e12657. doi: 10.2196/12657.

BACKGROUND: Data on contraceptive needs and use among young unmarried men are limited. Conventional ways of data collection may lead to limited and unreliable information on contraceptive use due to sensitivity of the topic, as many young men feel...

Sonography of tendon pathology in the hand and wrist.

Journal of ultrasonography

Rosskopf AB, Martinoli C, Sconfienza LM, Gitto S, Taljanovic MS, Picasso R, Klauser A.
PMID: 34970442
J Ultrason. 2021 Nov 29;21(87):e306-e317. doi: 10.15557/JoU.2021.0052. Epub 2021 Dec 15.

Traumatic and non-traumatic tendon lesions are common at the wrist and hand. For the diagnosis, therapy management, and long-term prognosis of tendon lesions, a detailed understanding of the complex anatomy and knowledge of typical injury patterns is crucial for...

Poor T-cell receptor β repertoire diversity early posttransplant for severe combined immunodeficiency predicts failure of immune reconstitution.

The Journal of allergy and clinical immunology

Delmonte OM, Castagnoli R, Yu J, Dvorak CC, Cowan MJ, Dávila Saldaña BJ, De Ravin SS, Mamcarz E, Chang CK, Daley SR, Griffith LM, Notarangelo LD, Puck JM.
PMID: 34384841
J Allergy Clin Immunol. 2021 Aug 09; doi: 10.1016/j.jaci.2021.07.029. Epub 2021 Aug 09.

BACKGROUND: Development of a diverse T-cell receptor β (TRB) repertoire is associated with immune recovery following hematopoietic cell transplantation (HCT) for severe combined immunodeficiency (SCID). High-throughput sequencing of the TRB repertoire allows evaluation of clonotype dynamics during immune reconstitution.OBJECTIVES:...

Short-chain aurachin D derivatives are selective inhibitors of E. coli cytochrome bd-I and bd-II oxidases.

Scientific reports

Radloff M, Elamri I, Grund TN, Witte LF, Hohmann KF, Nakagaki S, Goojani HG, Nasiri H, Hideto Miyoshi, Bald D, Xie H, Sakamoto J, Schwalbe H, Safarian S.
PMID: 34903826
Sci Rep. 2021 Dec 13;11(1):23852. doi: 10.1038/s41598-021-03288-7.

Cytochrome bd-type oxidases play a crucial role for survival of pathogenic bacteria during infection and proliferation. This role and the fact that there are no homologues in the mitochondrial respiratory chain qualify cytochrome bd as a potential antimicrobial target....

Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma.

Cancer discovery

Puca F, Yu F, Bartolacci C, Pettazzoni P, Carugo A, Huang-Hobbs E, Liu J, Zanca C, Carbone F, Del Poggetto E, Gumin J, Dasgupta P, Seth S, Srinivasan S, Lang FF, Sulman EP, Lorenzi PL, Tan L, Shan M, Tolstyka ZP, Kachman M, Zhang L, Gao S, Deem AK, Genovese G, Scaglioni PP, Lyssiotis CA, Viale A, Draetta GF.
PMID: 34039636
Cancer Discov. 2021 Nov;11(11):2904-2923. doi: 10.1158/2159-8290.CD-20-1437. Epub 2021 May 26.

Glioblastoma (GBM) is highly resistant to chemotherapies, immune-based therapies, and targeted inhibitors. To identify novel drug targets, we screened orthotopically implanted, patient-derived glioblastoma sphere-forming cells using an RNAi library to probe essential tumor cell metabolic programs. This identified high...

Evaluating Thresholds to Adopt Hypofractionated Preoperative Radiotherapy as Standard of Care in Sarcoma.

Sarcoma

Valle LF, Bernthal N, Eilber FC, Shabason JE, Bedi M, Kalbasi A.
PMID: 34720663
Sarcoma. 2021 Oct 26;2021:3735874. doi: 10.1155/2021/3735874. eCollection 2021.

INTRODUCTION: Data supporting hypofractionated preoperative radiation therapy (RT) for patients with extremity and trunk soft tissue sarcoma (STS) are currently limited to phase II single-institution studies. We sought to understand the type and thresholds of clinical evidence required for...

Ultrasonication Improves Solid Phase Synthesis of Peptides Specific for Fibroblast Growth Factor Receptor and for the Protein-Protein Interface RANK-TRAF6.

Molecules (Basel, Switzerland)

Silva RDM, Franco Machado J, Gonçalves K, Lucas FM, Batista S, Melo R, Morais TS, Correia JDG.
PMID: 34885928
Molecules. 2021 Dec 03;26(23). doi: 10.3390/molecules26237349.

Considering our interest in the use of peptides as potential target-specific drugs or as delivery vectors of metallodrugs for various biomedical applications, it is crucial to explore improved synthetic methodologies to accomplish the highest peptide crude purity in the...

Targeted protein degraders from an oncologist point of view: The Holy Grail of cancer therapy?.

Critical reviews in oncology/hematology

Ambrosini M, Fucà G, Duca M, Damian S, De Santis F, Corti F, Cresta S, de Braud F, Di Nicola M.
PMID: 34800655
Crit Rev Oncol Hematol. 2021 Nov 17;169:103532. doi: 10.1016/j.critrevonc.2021.103532. Epub 2021 Nov 17.

In the era of precision medicine, monoclonal antibodies and small molecule inhibitors are the mainstays of the biological therapy in patients with solid tumors. However, resistance to treatment and the "undruggability" of certain key oncogenic proteins emerged as major...

Showing 25 to 36 of 172 entries