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Showing 1741 to 1745 of 1745 entries
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Humanized Patient-Derived Xenograft Models of Ovarian Cancer.

Methods in molecular biology (Clifton, N.J.)

Gitto SB, George E, Medvedev S, Simpkins F, Powell DJ.
PMID: 34918300
Methods Mol Biol. 2022;2424:255-274. doi: 10.1007/978-1-0716-1956-8_17.

In vivo modeling of cancer is a critical step in testing novel therapeutic strategies to advance patient care. Here we describe how to develop a humanized patient-derived xenograft (PDX) model of ovarian cancer that uses orthotopically transplanted patient ovarian...

Phantom epistasis between unlinked loci.

Nature

Hemani G, Powell JE, Wang H, Shakhbazov K, Westra HJ, Esko T, Henders AK, McRae AF, Martin NG, Metspalu A, Franke L, Montgomery GW, Goddard ME, Gibson G, Yang J, Visscher PM.
PMID: 34381229
Nature. 2021 Aug;596(7871):E1-E3. doi: 10.1038/s41586-021-03765-z. Epub 2021 Aug 11.

No abstract available.

Systematic analysis of CD39, CD103, CD137, and PD-1 as biomarkers for naturally occurring tumor antigen-specific TILs.

European journal of immunology

Eiva MA, Omran DK, Chacon JA, Powell DJ.
PMID: 34505280
Eur J Immunol. 2022 Jan;52(1):96-108. doi: 10.1002/eji.202149329. Epub 2021 Sep 18.

The detection of tumor-specific T cells in solid tumors is integral to interrogate endogenous antitumor responses and to advance downstream therapeutic applications. Multiple biomarkers are reported to identify endogenous tumor-specific tumor-infiltrating lymphocytes (TILs), namely CD137, PD-1, CD103, and CD39;...

Characterization of Circulating and Urinary Biomarkers in the Fontan Circulation and Their Correlation With Cardiac Imaging.

The American journal of cardiology

Ghelani SJ, Opotowsky AR, Harrild DM, Powell AJ, Azcue N, Ahmad S, Clair NS, Bradwin G, Rathod RH.
PMID: 34903340
Am J Cardiol. 2022 Jan 01;162:177-183. doi: 10.1016/j.amjcard.2021.08.063.

Several circulating biomarkers have been found to play a role in the surveillance and risk stratification of heart failure without congenital heart disease, but these have not been widely studied in patients with single ventricles palliated with a Fontan...

The Effects of Social Distancing Policies on Non-SARS-CoV-2 Respiratory Pathogens.

Open forum infectious diseases

Nawrocki J, Olin K, Holdrege MC, Hartsell J, Meyers L, Cox C, Powell M, Cook CV, Jones J, Robbins T, Hemmert A, Ginocchio CC.
PMID: 34322558
Open Forum Infect Dis. 2021 Mar 17;8(7):ofab133. doi: 10.1093/ofid/ofab133. eCollection 2021 Jul.

BACKGROUND: The initial focus of the US public health response to coronavirus disease 2019 (COVID-19) was the implementation of numerous social distancing policies. While COVID-19 was the impetus for imposing these policies, it is not the only respiratory disease...

Showing 1741 to 1745 of 1745 entries