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Showing 397 to 405 of 405 entries
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Rapid pathogen-specific recruitment of immune effector cells in the skin by secreted toxins.

Nature microbiology

Nguyen TH, Cheung GYC, Rigby KM, Kamenyeva O, Kabat J, Sturdevant DE, Villaruz AE, Liu R, Piewngam P, Porter AR, Firdous S, Chiou J, Park MD, Hunt RL, Almufarriji FMF, Tan VY, Asiamah TK, McCausland JW, Fisher EL, Yeh AJ, Bae JS, Kobayashi SD, Wang JM, Barber DL, DeLeo FR, Otto M.
PMID: 34873293
Nat Microbiol. 2021 Dec 06; doi: 10.1038/s41564-021-01012-9. Epub 2021 Dec 06.

Swift recruitment of phagocytic leucocytes is critical in preventing infection when bacteria breach through the protective layers of the skin. According to canonical models, this occurs via an indirect process that is initiated by contact of bacteria with resident...

Rapid pathogen-specific recruitment of immune effector cells in the skin by secreted toxins.

Nature microbiology

Nguyen TH, Cheung GYC, Rigby KM, Kamenyeva O, Kabat J, Sturdevant DE, Villaruz AE, Liu R, Piewngam P, Porter AR, Firdous S, Chiou J, Park MD, Hunt RL, Almufarriji FMF, Tan VY, Asiamah TK, McCausland JW, Fisher EL, Yeh AJ, Bae JS, Kobayashi SD, Wang JM, Barber DL, DeLeo FR, Otto M.
PMID: 34873293
Nat Microbiol. 2021 Dec 06; doi: 10.1038/s41564-021-01012-9. Epub 2021 Dec 06.

Swift recruitment of phagocytic leucocytes is critical in preventing infection when bacteria breach through the protective layers of the skin. According to canonical models, this occurs via an indirect process that is initiated by contact of bacteria with resident...

Cognition in mood disorders.

BJPsych open

Douglas KM, Porter RJ, Young AH.
PMID: 33308366
BJPsych Open. 2020 Dec 14;7(1):e16. doi: 10.1192/bjo.2020.149.

Cognitive impairment plays a key role in determining the course of illness and functional outcomes in mood disorders. This article summarises and discusses important papers within this thematic series of BJPsych Open that contribute to a greater understanding of...

International Core Outcome Set for Acute Simple Appendicitis in Children: Results of A Systematic Review, Delphi Study, and Focus Groups with Young People.

Annals of surgery

Knaapen M, Hall NJ, Moulin D, van der Lee JH, Butcher NJ, Minneci PC, Svensson JF, St Peter SD, Adams S, Nah SA, Skarsgard ED, Zani A, Emil S, Suominen JS, Aziz DA, Rai R, Offringa M, van Heurn EW, Bakx R, Gorter RR.
PMID: 33630468
Ann Surg. 2020 Dec 29; doi: 10.1097/SLA.0000000000004707. Epub 2020 Dec 29.

OBJECTIVE:: To develop an international Core Outcome Set (COS), a minimal collection of outcomes that should be measured and reported in all future clinical trials evaluating treatments of acute simple appendicitis in children.SUMMARY BACKGROUND DATA: A previous systematic review...

A randomised controlled trial of psychotherapy and cognitive remediation to target cognition in mood disorders.

Acta psychiatrica Scandinavica

Douglas KM, Groves S, Crowe MT, Inder ML, Jordan J, Carlyle D, Wells H, Beaglehole B, Mulder R, Lacey C, Luty SE, Eggleston K, Frampton CMA, Bowie CR, Porter RJ.
PMID: 34800298
Acta Psychiatr Scand. 2021 Nov 20; doi: 10.1111/acps.13387. Epub 2021 Nov 20.

OBJECTIVE: To examine the impact of a treatment package combining Interpersonal and Social Rhythm Therapy (IPSRT) and cognitive remediation (CR), vs IPSRT alone, on cognition, functioning, and mood disturbance outcomes in mood disorders.METHODS: A pragmatic randomised controlled trial in...

Longitudinal optical coherence tomography to visualize the in vivo response of middle ear biofilms to antibiotic therapy.

Scientific reports

Won J, Hong W, Khampang P, Spillman DR, Marshall S, Yan K, Porter RG, Novak MA, Kerschner JE, Boppart SA.
PMID: 33664323
Sci Rep. 2021 Mar 04;11(1):5176. doi: 10.1038/s41598-021-84543-9.

Studying the impact of antibiotic treatment on otitis media (OM), the leading cause of primary care office visits during childhood, is critical to develop appropriate treatment strategies. Tracking dynamic middle ear conditions during antibiotic treatment is not readily applicable...

Development of a Recombinant Pichinde Virus-Vectored Vaccine against Turkey Arthritis Reovirus and Its Immunological Response Characterization in Vaccinated Animals.

Pathogens (Basel, Switzerland)

Kumar P, Sharafeldin TA, Kumar R, Huang Q, Liang Y, Goyal SM, Porter RE, Ly H, Mor SK.
PMID: 33668435
Pathogens. 2021 Feb 13;10(2). doi: 10.3390/pathogens10020197.

Vaccination may be an effective way to reduce turkey arthritis reovirus (TARV)-induced lameness in turkey flocks. However, there are currently no commercial vaccines available against TARV infection. Here, we describe the use of reverse genetics technology to generate a...

Myocardial function reclassification: Echocardiographic strain patterns in patients with chronic Chagas cardiomyopathy and intraventricular dyssynchrony.

International journal of cardiology

Athayde GAT, Borges BCC, Pinheiro AO, Souza AL, Oliveira CP, Martins SAM, Teixeira RA, Siqueira SF, Porter TR, Mathias Junior W, Martinelli Filho M.
PMID: 34890764
Int J Cardiol. 2021 Dec 08; doi: 10.1016/j.ijcard.2021.12.005. Epub 2021 Dec 08.

BACKGROUND: We aimed to identify, among Chronic Chagas Cardiomyopathy (CCC) patients with left ventricular dysfunction (LVD) and non-left bundle branch block (non-LBBB), subgroups with different functional and mechanical patterns of global longitudinal strain (GLS) and intraventricular dyssynchrony (IVD) at...

Addiction and "Generation Me:" Narcissistic and Prosocial Behaviors of Adolescents with Substance Dependency Disorder in Comparison to Normative Adolescents.

Alcoholism treatment quarterly

Carter RR, Johnson SM, Exline JJ, Post SG, Pagano ME.
PMID: 22544995
Alcohol Treat Q. 2012;30(2):163-178. doi: 10.1080/07347324.2012.663286. Epub 2012 Apr 13.

The purpose of this study is to explore narcissistic and prosocial behaviors as reported by adolescents with and without substance dependency disorder (SDD). This study employs a quasi-experimental design using SDD adolescents compared with two normative samples of adolescents....

Showing 397 to 405 of 405 entries