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Showing 25 to 36 of 205 entries
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Dual-Targeting Peptide-Guided Approach for Precision Delivery and Cancer Monitoring by Using a Safe Upconversion Nanoplatform.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Zha S, Chau HF, Chau WY, Chan LS, Lin J, Lo KW, Cho WC, Yip YL, Tsao SW, Farrell PJ, Feng L, Di JM, Law GL, Lung HL, Wong KL.
PMID: 33717845
Adv Sci (Weinh). 2021 Jan 06;8(5):e2002919. doi: 10.1002/advs.202002919. eCollection 2021 Mar.

Using Epstein-Barr virus (EBV)-induced cancer cells and HeLa cells as a comparative study model, a novel and safe dual-EBV-oncoproteins-targeting pH-responsive peptide engineering, coating, and guiding approach to achieve precision targeting and treatment strategy against EBV-associated cancers is introduced. Individual...

Allergies, genetic polymorphisms of Th2 interleukins, and childhood acute lymphoblastic leukemia: The ESTELLE study.

Pediatric blood & cancer

Ajrouche R, Chandab G, Petit A, Strullu M, Nelken B, Plat G, Michel G, Domenech C, Clavel J, Bonaventure A.
PMID: 34662484
Pediatr Blood Cancer. 2021 Oct 18;e29402. doi: 10.1002/pbc.29402. Epub 2021 Oct 18.

CONTEXT: A negative association between a history of allergy and childhood acute lymphoblastic leukemia (ALL) has been reported in previous studies, but remains debated. This work aimed to investigate this association accounting for genetic polymorphisms of the Th2 pathway...

Fertility status among long-term childhood acute lymphoblastic leukaemia survivors enrolled between 1971 and 1998 in EORTC CLG studies: results of the 58 Late Adverse Effects study.

Human reproduction (Oxford, England)

Rossi G, Kicinski M, Suciu S, Vandecruys E, Plat G, Uyttebroeck A, Paillard C, Barbati M, Dresse MF, Simon P, Minckes O, Pluchart C, Ferster A, Freycon C, Millot F, van der Werff Ten Bosch J, Chantrain C, Paulus R, de Rojas T, de Schaetzen G, Rohrlich P, Benoit Y, Piette C.
PMID: 34788455
Hum Reprod. 2021 Nov 11; doi: 10.1093/humrep/deab236. Epub 2021 Nov 11.

STUDY QUESTION: What are the fertility outcomes of male and female childhood acute lymphoblastic leukaemia (ALL) long-term survivors?SUMMARY ANSWER: We observed similar fertility outcomes in both male and female childhood ALL survivors compared with the general population, with the...

Lanthanide supramolecular helical diastereoselective breaking induced by point chirality: mixture or P-helix, M-helix.

Chemical communications (Cambridge, England)

Yeung CT, Chan WT, Yan SC, Yu KL, Yim KH, Wong WT, Law GL.
PMID: 25415266
Chem Commun (Camb). 2015 Jan 11;51(3):592-5. doi: 10.1039/c4cc08362h. Epub 2014 Nov 21.

The self-assembly of lanthanide (europium or lanthanium) bimetallic triple helicates from two closely related chiral ligands resulted in a very different supramolecular phenomenon. One gave rise to significantly diastereoselective formation of a triple helicate, whereas the other led to...

Interband Absorption Enhanced Optical Activity in Discrete Au@Ag Core-Shell Nanocuboids: Probing Extended Helical Conformation of Chemisorbed Cysteine Molecules.

Angewandte Chemie (International ed. in English)

Bao ZY, Zhang W, Zhang YL, He J, Dai J, Yeung CT, Law GL, Lei DY.
PMID: 28004466
Angew Chem Int Ed Engl. 2017 Jan 24;56(5):1283-1288. doi: 10.1002/anie.201607563. Epub 2016 Dec 22.

Detailed understanding of the interaction between a chiral molecule and a noble metal surface is essential to rationalize and advance interfacial self-assembly of amino acids and metal-mediated anchoring of proteins. Here we demonstrate that individual Au@Ag core-shell nanocuboids can...

Fertility status among long-term childhood acute lymphoblastic leukaemia survivors enrolled between 1971 and 1998 in EORTC CLG studies: results of the 58 Late Adverse Effects study.

Human reproduction (Oxford, England)

Rossi G, Kicinski M, Suciu S, Vandecruys E, Plat G, Uyttebroeck A, Paillard C, Barbati M, Dresse MF, Simon P, Minckes O, Pluchart C, Ferster A, Freycon C, Millot F, van der Werff Ten Bosch J, Chantrain C, Paulus R, de Rojas T, de Schaetzen G, Rohrlich P, Benoit Y, Piette C.
PMID: 34788455
Hum Reprod. 2021 Dec 27;37(1):44-53. doi: 10.1093/humrep/deab236.

STUDY QUESTION: What are the fertility outcomes of male and female childhood acute lymphoblastic leukaemia (ALL) long-term survivors?SUMMARY ANSWER: We observed similar fertility outcomes in both male and female childhood ALL survivors compared with the general population, with the...

Sex-Based Dimorphism of Anticancer Immune Response and Molecular Mechanisms of Immune Evasion.

Clinical cancer research : an official journal of the American Association for Cancer Research

Conforti F, Pala L, Pagan E, Bagnardi V, De Pas T, Queirolo P, Pennacchioli E, Catania C, Cocorocchio E, Ferrucci PF, Saponara M, Orsolini G, Zagami P, Nicoló E, De Marinis F, Tortora G, Bria E, Minucci S, Joffe H, Veronesi P, Wargo J, Rosenthal R, Swanton C, Mantovani A, Gelber RD, Viale G, Goldhirsch A, Giaccone G.
PMID: 34016641
Clin Cancer Res. 2021 Aug 01;27(15):4311-4324. doi: 10.1158/1078-0432.CCR-21-0136. Epub 2021 May 20.

PURPOSE: We previously demonstrated that sex influences response to immune checkpoint inhibitors. In this article, we investigate sex-based differences in the molecular mechanisms of anticancer immune response and immune evasion in patients with NSCLC.EXPERIMENTAL DESIGN: We analyzed (i) transcriptome...

Chiral Organic Chromophoric Systems in the Enhancement of Circularly Polarized Luminescence.

Frontiers in chemistry

Wu T, Zheng YX, Longhi G, Law GL.
PMID: 33708760
Front Chem. 2021 Feb 23;9:635655. doi: 10.3389/fchem.2021.635655. eCollection 2021.

No abstract available.

Recurrent bacterial infections, but not fungal infections, characterise patients with ELANE-related neutropenia: a French Severe Chronic Neutropenia Registry study.

British journal of haematology

Rotulo GA, Plat G, Beaupain B, Blanche S, Moushous D, Sicre de Fontbrune F, Leblanc T, Renard C, Barlogis V, Vigue MG, Freycon C, Piguet C, Pasquet M, Fieschi C, Abou-Chahla W, Gandemer V, Rialland F, Millot F, Marie-Cardine A, Paillard C, Levy P, Aladjidi N, Biosse-Duplan M, Bellanné-Chantelot C, Donadieu J.
PMID: 34340247
Br J Haematol. 2021 Sep;194(5):908-920. doi: 10.1111/bjh.17695. Epub 2021 Aug 02.

Among 143 patients with elastase, neutrophil-expressed (ELANE)-related neutropenia enrolled in the French Severe Chronic Neutropenia Registry, 94 were classified as having severe chronic neutropenia (SCN) and 49 with cyclic neutropenia (CyN). Their infectious episodes were classified as severe, mild...

Prevalence of anabolic steroid use among illinois high school students.

Journal of athletic training

Tuttle LD, Gaa GL, Griffith EH, Cahill BR.
PMID: 16558283
J Athl Train. 1994 Sep;29(3):216-22.

This study was conducted to quantify anabolic steroid use in Illinois, investigate student knowledge and perception of anabolic steroid use, and identify characteristics of the anabolic steroid user. We surveyed 3047 freshman and senior high school students from 38...

Tris(1H-benzimidazol-3-ium-2-ylmeth-yl)amine tris-(2,4,6-trinitro-phenolate) acetonitrile disolvate.

Acta crystallographica. Section E, Structure reports online

Bai Y, Yuan JK, Wang H, Pan GL, Wu HL.
PMID: 22719675
Acta Crystallogr Sect E Struct Rep Online. 2012 Jun 01;68:o1922. doi: 10.1107/S160053681202329X. Epub 2012 May 31.

In the cation of the title salt, C(24)H(24)N(7) (3+)·3C(6)H(2)N(3)O(7) (-)·2C(2)H(3)N, the three benzimidazolium ring systems are oriented to each other at dihedral angles of 10.42 (7), 23.98 (7) and 22.17 (7)°. In the crystal, the cation links to the...

Arthroscopic excision of intra-articular hip osteoid osteoma: a report of 2 cases.

Case reports in orthopedics

Nehme AH, Bou Ghannam AG, Imad JP, Jabbour FC, Moucharafieh R, Wehbe J.
PMID: 23304593
Case Rep Orthop. 2012;2012:820501. doi: 10.1155/2012/820501. Epub 2012 Dec 11.

Intra-articular osteoid osteoma is uncommon accounting for approximately 12% of all osteoid osteomas. It presents diagnostic and therapeutic challenges since several traumatic or degenerative pathologies of the joint can be simulated with delay in the diagnosis. We report the...

Showing 25 to 36 of 205 entries