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Design of Functional Chiral Cyclen-Based Radiometal Chelators for Theranostics.

Inorganic chemistry

Dai L, Zhang J, Wong CT, Chan WTK, Ling X, Anderson CJ, Law GL.
PMID: 33689299
Inorg Chem. 2021 May 17;60(10):7082-7088. doi: 10.1021/acs.inorgchem.0c03734. Epub 2021 Mar 09.

A series of water-soluble chiral cyclen-based chelators with chemical handles for selective targeting have been synthesized (cyclen = 1,4,7,10-Tetraazacyclododecane). Optical studies, relaxivity measurements, and competitive titrations were performed to show the versatility of these chiral chelators. The complexations of...

Showing 205 to 205 of 205 entries