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Showing 37 to 48 of 1918 entries
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Influence of Leaving-Group Electronic Effect on alpha-Chymotrypsin: Catalytic Constants of Specific Substrates.

Proceedings of the National Academy of Sciences of the United States of America

Philipp M, Pollack RM, Bender ML.
PMID: 16592059
Proc Natl Acad Sci U S A. 1973 Feb;70(2):517-20. doi: 10.1073/pnas.70.2.517.

Rate constants and binding constants for the alpha-chymotrypsin-catalyzed hydrolysis of N-acetyltyrosine, tryptophan, and phenylalanine anilides are presented. Both k(cat) and K(m) are independent of electronic effects in the substrate over a range of 9.8 orders of magnitude (as measured...

Quantification of single fluid inclusions by combining synchrotron radiation-induced micro-X-ray fluorescence and transmission.

Analytical chemistry

Cauzid J, Philippot P, Somogyi A, Simionovici A, Bleuet P.
PMID: 15253633
Anal Chem. 2004 Jul 15;76(14):3988-94. doi: 10.1021/ac035533f.

Fluid inclusions represent the only direct samples of ancient fluids in many crustal rocks; precise knowledge of their chemical composition provides crucial information to model paleofluid-rock interactions and hydrothermal transport processes. Owing to its nondestructive character, micrometer-scale spatial resolution,...

Reflections on complementary and alternative medicine.

The Journal of the Kentucky Medical Association

Browne PT.
PMID: 15291137
J Ky Med Assoc. 2004 Jul;102(7):325.

No abstract available.

[Psychological aspects of cancer Information dedicated to patients and relatives].

Bulletin du cancer

Machavoine JL, Bonnet V, Leichtnam-Dugarin L, Dolbeault S, Marx E, Dauchy S, Flahault C, Bendrihen N, Pelicier N, Syp L, Pérennec ME, Dilhuydy JM, Marx G, Chaussumier C, Brusco S, Carretier J, Delavigne V, Fervers B, Philip T.
PMID: 17338095
Bull Cancer. 2007 Feb;94(2):203-11.

In response to the evolution of the information-seeking behaviour of patients and concerns from health professionals regarding cancer patient information, the French National Federation of Comprehensive Cancer Centres (FNCLCC) introduced, in 1998, an information and education program dedicated to...

Elegance of disordered granular packings: a validation of Edward's hypothesis.

Physical review letters

Metzger PT, Donahue CM.
PMID: 15904114
Phys Rev Lett. 2005 Apr 15;94(14):148001. doi: 10.1103/PhysRevLett.94.148001. Epub 2005 Apr 14.

We have found a way to analyze Edwards' density of states for static granular packings in the special case of round, rigid, frictionless grains assuming a constant coordination number. It obtains the most entropic density of single grain states,...

German education.

Science (New York, N.Y.)

Philipp M.
PMID: 17817621
Science. 1996 Aug 23;273(5278):1030a. doi: 10.1126/science.273.5278.1030a.

No abstract available.

Remission with venlafaxine extended release or selective serotonin reuptake inhibitors in depressed patients: a randomized, open-label study.

The primary care companion for CNS disorders

Thase ME, Ninan PT, Musgnung JJ, Trivedi MH.
PMID: 21731835
Prim Care Companion CNS Disord. 2011;13(1). doi: 10.4088/PCC.10m00979blu.

BACKGROUND: This randomized, open-label, rater-blinded, multicenter study compared treatment outcomes with the serotonin-norepinephrine reuptake inhibitor (SNRI) venlafaxine extended release (ER) with selective serotonin reuptake inhibitors (SSRIs) in primary care patients with major depressive disorder.METHOD: Study data were collected from...

Global classical solutions of the Boltzmann equation with long-range interactions.

Proceedings of the National Academy of Sciences of the United States of America

Gressman PT, Strain RM.
PMID: 20231489
Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5744-9. doi: 10.1073/pnas.1001185107. Epub 2010 Mar 15.

This is a brief announcement of our recent proof of global existence and rapid decay to equilibrium of classical solutions to the Boltzmann equation without any angular cutoff, that is, for long-range interactions. We consider perturbations of the Maxwellian...

Posaconazole in the management of refractory invasive fungal infections.

Therapeutics and clinical risk management

Langner S, Staber PB, Neumeister P.
PMID: 19209257
Ther Clin Risk Manag. 2008 Aug;4(4):747-58. doi: 10.2147/tcrm.s3329.

The rising incidence of invasive fungal infections due to the expanding population of immunocompromised hosts and the increasing prevalence of fungal resistance has led to the need for novel antifungal agents. Posaconazole, a new member of the triazole class...

DNA indels in coding regions reveal selective constraints on protein evolution in the human lineage.

BMC evolutionary biology

de la Chaux N, Messer PW, Arndt PF.
PMID: 17935613
BMC Evol Biol. 2007 Oct 12;7:191. doi: 10.1186/1471-2148-7-191.

BACKGROUND: Insertions and deletions of DNA segments (indels) are together with substitutions the major mutational processes that generate genetic variation. Here we focus on recent DNA insertions and deletions in protein coding regions of the human genome to investigate...

Rate of gas phase association of hydroxyl radical and nitrogen dioxide.

Science (New York, N.Y.)

Mollner AK, Valluvadasan S, Feng L, Sprague MK, Okumura M, Milligan DB, Bloss WJ, Sander SP, Martien PT, Harley RA, McCoy AB, Carter WP.
PMID: 21030650
Science. 2010 Oct 29;330(6004):646-9. doi: 10.1126/science.1193030.

The reaction of OH and NO(2) to form gaseous nitric acid (HONO(2)) is among the most influential in atmospheric chemistry. Despite its importance, the rate coefficient remains poorly determined under tropospheric conditions because of difficulties in making laboratory rate...

Desvenlafaxine and weight change in major depressive disorder.

Primary care companion to the Journal of clinical psychiatry

Tourian KA, Leurent C, Graepel J, Ninan PT.
PMID: 20582292
Prim Care Companion J Clin Psychiatry. 2010;12(1):PCC.08m00746. doi: 10.4088/PCC.08m00746blu.

OBJECTIVE: To characterize weight change during short- and longer-term treatment with desvenlafaxine (administered as desvenlafaxine succinate) for major depressive disorder (MDD).METHOD: Data from 9 short-term, double-blind, placebo-controlled studies and 1 longer-term relapse-prevention trial conducted between September 2002 and January...

Showing 37 to 48 of 1918 entries