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Showing 337 to 345 of 345 entries
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Upregulation of estrogen receptor alpha (ERα) expression in transgenic mice expressing human CYP4Z1.

Breast cancer research and treatment

Khayeka-Wandabwa C, Zhao J, Pathak JL, Wu H, Bureik M.
PMID: 34725776
Breast Cancer Res Treat. 2021 Nov 01; doi: 10.1007/s10549-021-06435-w. Epub 2021 Nov 01.

PURPOSE: CYP4Z1 is a human cytochrome P450 enzyme involved in breast cancer progression and prognosis, but its functional role in these processes is not understood. In order to gain more insight into CYP4Z1's properties it was recombinantly expressed in...

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Khayeka-Wandabwa C, Zhao J, Pathak JL, et al. Upregulation of estrogen receptor alpha (ERα) expression in transgenic mice expressing human CYP4Z1. Breast Cancer Res Treat. 2021;doi: 10.1007/s10549-021-06435-w.
Khayeka-Wandabwa, C., Zhao, J., Pathak, J. L., Wu, H., & Bureik, M. (2021). Upregulation of estrogen receptor alpha (ERα) expression in transgenic mice expressing human CYP4Z1. Breast cancer research and treatment, . https://doi.org/10.1007/s10549-021-06435-w
Khayeka-Wandabwa, Christopher, et al. "Upregulation of estrogen receptor alpha (ERα) expression in transgenic mice expressing human CYP4Z1." Breast cancer research and treatment vol. (2021). doi: https://doi.org/10.1007/s10549-021-06435-w
Khayeka-Wandabwa C, Zhao J, Pathak JL, Wu H, Bureik M. Upregulation of estrogen receptor alpha (ERα) expression in transgenic mice expressing human CYP4Z1. Breast Cancer Res Treat. 2021 Nov 01; doi: 10.1007/s10549-021-06435-w. Epub 2021 Nov 01. PMID: 34725776.
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"The Janus Face" of Thrombocytes in COVID-19.

Current health sciences journal

Singh S, Singh AR, Pathak BK, Mohakuda SS, Tilak T.
PMID: 34211762
Curr Health Sci J. 2021 Jan-Mar;47(1):139-142. doi: 10.12865/CHSJ.47.01.23. Epub 2021 Mar 31.

A 55 year old patient of COVID-19, with no known comorbidities presented with fever, myalgia and headache and at presentation had leukopenia and thrombocytopenia, however did not have any bleeding manifestations. The patient's inflammatory markers including ferritin and C-reactive...

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Singh S, Singh AR, Pathak BK, et al. "The Janus Face" of Thrombocytes in COVID-19. Curr Health Sci J. 2021;47(1):139-142doi: 10.12865/CHSJ.47.01.23.
Singh, S., Singh, A. R., Pathak, B. K., Mohakuda, S. S., & Tilak, T. (2021). "The Janus Face" of Thrombocytes in COVID-19. Current health sciences journal, 47(1), 139-142. https://doi.org/10.12865/CHSJ.47.01.23
Singh, Suhail, et al. ""The Janus Face" of Thrombocytes in COVID-19." Current health sciences journal vol. 47,1 (2021): 139-142. doi: https://doi.org/10.12865/CHSJ.47.01.23
Singh S, Singh AR, Pathak BK, Mohakuda SS, Tilak T. "The Janus Face" of Thrombocytes in COVID-19. Curr Health Sci J. 2021 Jan-Mar;47(1):139-142. doi: 10.12865/CHSJ.47.01.23. Epub 2021 Mar 31. PMID: 34211762; PMCID: PMC8200617.
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Sugar Beet Cultivation in India: Prospects for Bio-Ethanol Production and Value-Added Co-Products.

Sugar tech : an international journal of sugar crops & related industries

Mall AK, Misra V, Santeshwari, Pathak AD, Srivastava S.
PMID: 34248307
Sugar Tech. 2021 Jul 07;1-17. doi: 10.1007/s12355-021-01007-0. Epub 2021 Jul 07.

Sugar beet is an important crop in the advent of COVID 19 as it has a high potential for ethanol production in less growth span. The life cycle of this crop is of five to six months with a...

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Mall AK, Misra V, Santeshwari, et al. Sugar Beet Cultivation in India: Prospects for Bio-Ethanol Production and Value-Added Co-Products. Sugar Tech. 2021;1-17doi: 10.1007/s12355-021-01007-0.
Mall, A. K., Misra, V., Santeshwari, Pathak, A. D., & Srivastava, S. (2021). Sugar Beet Cultivation in India: Prospects for Bio-Ethanol Production and Value-Added Co-Products. Sugar tech : an international journal of sugar crops & related industries, 1-17. https://doi.org/10.1007/s12355-021-01007-0
Mall, Ashutosh Kumar, et al. "Sugar Beet Cultivation in India: Prospects for Bio-Ethanol Production and Value-Added Co-Products." Sugar tech : an international journal of sugar crops & related industries vol. (2021): 1-17. doi: https://doi.org/10.1007/s12355-021-01007-0
Mall AK, Misra V, Santeshwari, Pathak AD, Srivastava S. Sugar Beet Cultivation in India: Prospects for Bio-Ethanol Production and Value-Added Co-Products. Sugar Tech. 2021 Jul 07;1-17. doi: 10.1007/s12355-021-01007-0. Epub 2021 Jul 07. PMID: 34248307; PMCID: PMC8261398.
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Impact of COVID-19 pandemic on non-COVID patient's management in urology: a public hospital experience in Mumbai.

African journal of urology : the official journal of the Pan African Urological Surgeons' Association (PAUSA)

Jibhakate NA, Patwardhan SK, Sawant AS, Pathak HR, Patil BP, Kamal H.
PMID: 34248350
Afr J Urol. 2021;27(1):96. doi: 10.1186/s12301-021-00196-0. Epub 2021 Jul 06.

BACKGROUND: To evaluate the impact of COVID-19 lockdown on non-COVID urological patient's management in tertiary care urology centres.METHODS: This is an observational study in which data of patients visiting the urology department of all the MCGM run tertiary care...

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Jibhakate NA, Patwardhan SK, Sawant AS, et al. Impact of COVID-19 pandemic on non-COVID patient's management in urology: a public hospital experience in Mumbai. Afr J Urol. 2021;27(1):96doi: 10.1186/s12301-021-00196-0.
Jibhakate, N. A., Patwardhan, S. K., Sawant, A. S., Pathak, H. R., Patil, B. P., & Kamal, H. (2021). Impact of COVID-19 pandemic on non-COVID patient's management in urology: a public hospital experience in Mumbai. African journal of urology : the official journal of the Pan African Urological Surgeons' Association (PAUSA), 27(1), 96. https://doi.org/10.1186/s12301-021-00196-0
Jibhakate, Nikhilesh A, et al. "Impact of COVID-19 pandemic on non-COVID patient's management in urology: a public hospital experience in Mumbai." African journal of urology : the official journal of the Pan African Urological Surgeons' Association (PAUSA) vol. 27,1 (2021): 96. doi: https://doi.org/10.1186/s12301-021-00196-0
Jibhakate NA, Patwardhan SK, Sawant AS, Pathak HR, Patil BP, Kamal H. Impact of COVID-19 pandemic on non-COVID patient's management in urology: a public hospital experience in Mumbai. Afr J Urol. 2021;27(1):96. doi: 10.1186/s12301-021-00196-0. Epub 2021 Jul 06. PMID: 34248350; PMCID: PMC8258485.
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Characterizing the effect of background selection on the polygenicity of brain-related traits.

Genomics

Wendt FR, Pathak GA, Overstreet C, Tylee DS, Gelernter J, Atkinson EG, Polimanti R.
PMID: 33278486
Genomics. 2021 Jan;113(1):111-119. doi: 10.1016/j.ygeno.2020.11.032. Epub 2020 Dec 02.

BACKGROUND: Genome-wide association studies (GWAS) have demonstrated that psychopathology phenotypes are affected by many risk alleles with small effect (polygenicity). It is unclear how ubiquitously evolutionary pressures influence the genetic architecture of these traits.METHODS: We partitioned SNP heritability to...

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Wendt FR, Pathak GA, Overstreet C, et al. Characterizing the effect of background selection on the polygenicity of brain-related traits. Genomics. 2020;113(1):111-119doi: 10.1016/j.ygeno.2020.11.032.
Wendt, F. R., Pathak, G. A., Overstreet, C., Tylee, D. S., Gelernter, J., Atkinson, E. G., & Polimanti, R. (2021). Characterizing the effect of background selection on the polygenicity of brain-related traits. Genomics, 113(1), 111-119. https://doi.org/10.1016/j.ygeno.2020.11.032
Wendt, Frank R, et al. "Characterizing the effect of background selection on the polygenicity of brain-related traits." Genomics vol. 113,1 (2021): 111-119. doi: https://doi.org/10.1016/j.ygeno.2020.11.032
Wendt FR, Pathak GA, Overstreet C, Tylee DS, Gelernter J, Atkinson EG, Polimanti R. Characterizing the effect of background selection on the polygenicity of brain-related traits. Genomics. 2021 Jan;113(1):111-119. doi: 10.1016/j.ygeno.2020.11.032. Epub 2020 Dec 02. PMID: 33278486; PMCID: PMC7855394.
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Host Genetic Liability for Severe COVID-19 Associates with Alcohol Drinking Behavior and Diabetic Outcomes in Participants of European Descent.

Frontiers in genetics

Wendt FR, De Lillo A, Pathak GA, De Angelis F, Polimanti R.
PMID: 34966408
Front Genet. 2021 Dec 13;12:765247. doi: 10.3389/fgene.2021.765247. eCollection 2021.

Risk factors and long-term consequences of COVID-19 infection are unclear but can be investigated with large-scale genomic data. To distinguish correlation from causation, we performed

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Wendt FR, De Lillo A, Pathak GA, et al. Host Genetic Liability for Severe COVID-19 Associates with Alcohol Drinking Behavior and Diabetic Outcomes in Participants of European Descent. Front Genet. 2021;12:765247doi: 10.3389/fgene.2021.765247.
Wendt, F. R., De Lillo, A., Pathak, G. A., De Angelis, F., & Polimanti, R. (2021). Host Genetic Liability for Severe COVID-19 Associates with Alcohol Drinking Behavior and Diabetic Outcomes in Participants of European Descent. Frontiers in genetics, 12765247. https://doi.org/10.3389/fgene.2021.765247
Wendt, Frank R, et al. "Host Genetic Liability for Severe COVID-19 Associates with Alcohol Drinking Behavior and Diabetic Outcomes in Participants of European Descent." Frontiers in genetics vol. 12 (2021): 765247. doi: https://doi.org/10.3389/fgene.2021.765247
Wendt FR, De Lillo A, Pathak GA, De Angelis F, Polimanti R. Host Genetic Liability for Severe COVID-19 Associates with Alcohol Drinking Behavior and Diabetic Outcomes in Participants of European Descent. Front Genet. 2021 Dec 13;12:765247. doi: 10.3389/fgene.2021.765247. eCollection 2021. PMID: 34966408; PMCID: PMC8711039.
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Cross-ancestry genome-wide association studies identified heterogeneous loci associated with differences of allele frequency and regulome tagging between participants of European descent and other ancestry groups from the UK Biobank.

Human molecular genetics

De Lillo A, D'Antona S, Pathak GA, Wendt FR, De Angelis F, Fuciarelli M, Polimanti R.
PMID: 33890984
Hum Mol Genet. 2021 Jul 09;30(15):1457-1467. doi: 10.1093/hmg/ddab114.

To investigate cross-ancestry genetics of complex traits, we conducted a phenome-wide analysis of loci with heterogeneous effects across African, Admixed-American, Central/South Asian, East Asian, European and Middle Eastern participants of the UK Biobank (N = 441 331). Testing 843...

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De Lillo A, D'Antona S, Pathak GA, et al. Cross-ancestry genome-wide association studies identified heterogeneous loci associated with differences of allele frequency and regulome tagging between participants of European descent and other ancestry groups from the UK Biobank. Hum Mol Genet. 2021;30(15):1457-1467doi: 10.1093/hmg/ddab114.
De Lillo, A., D'Antona, S., Pathak, G. A., Wendt, F. R., De Angelis, F., Fuciarelli, M., & Polimanti, R. (2021). Cross-ancestry genome-wide association studies identified heterogeneous loci associated with differences of allele frequency and regulome tagging between participants of European descent and other ancestry groups from the UK Biobank. Human molecular genetics, 30(15), 1457-1467. https://doi.org/10.1093/hmg/ddab114
De Lillo, Antonella, et al. "Cross-ancestry genome-wide association studies identified heterogeneous loci associated with differences of allele frequency and regulome tagging between participants of European descent and other ancestry groups from the UK Biobank." Human molecular genetics vol. 30,15 (2021): 1457-1467. doi: https://doi.org/10.1093/hmg/ddab114
De Lillo A, D'Antona S, Pathak GA, Wendt FR, De Angelis F, Fuciarelli M, Polimanti R. Cross-ancestry genome-wide association studies identified heterogeneous loci associated with differences of allele frequency and regulome tagging between participants of European descent and other ancestry groups from the UK Biobank. Hum Mol Genet. 2021 Jul 09;30(15):1457-1467. doi: 10.1093/hmg/ddab114. PMID: 33890984; PMCID: PMC8283210.
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Temporal .

ACS omega

Tiwari D, Jakhmola S, Pathak DK, Kumar R, Jha HC.
PMID: 33225186
ACS Omega. 2020 Nov 04;5(45):29547-29560. doi: 10.1021/acsomega.0c04525. eCollection 2020 Nov 17.

Raman spectroscopy can be used as a tool to study virus entry and pathogen-driven manipulation of the host efficiently. To date, Epstein-Barr virus (EBV) entry and altered biochemistry of the glial cell upon infection are elusive. In this study,...

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Tiwari D, Jakhmola S, Pathak DK, et al. Temporal . ACS Omega. 2020;5(45):29547-29560doi: 10.1021/acsomega.0c04525.
Tiwari, D., Jakhmola, S., Pathak, D. K., Kumar, R., & Jha, H. C. (2020). Temporal . ACS omega, 5(45), 29547-29560. https://doi.org/10.1021/acsomega.0c04525
Tiwari, Deeksha, et al. "Temporal ." ACS omega vol. 5,45 (2020): 29547-29560. doi: https://doi.org/10.1021/acsomega.0c04525
Tiwari D, Jakhmola S, Pathak DK, Kumar R, Jha HC. Temporal . ACS Omega. 2020 Nov 04;5(45):29547-29560. doi: 10.1021/acsomega.0c04525. eCollection 2020 Nov 17. PMID: 33225186; PMCID: PMC7676301.
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Entinostat, a selective HDAC1/2 inhibitor, potentiates the effects of olaparib in homologous recombination proficient ovarian cancer.

Gynecologic oncology

Gupta VG, Hirst J, Petersen S, Roby KF, Kusch M, Zhou H, Clive ML, Jewell A, Pathak HB, Godwin AK, Wilson AJ, Crispens MA, Cybulla E, Vindigni A, Fuh KC, Khabele D.
PMID: 33867143
Gynecol Oncol. 2021 Jul;162(1):163-172. doi: 10.1016/j.ygyno.2021.04.015. Epub 2021 Apr 16.

OBJECTIVE: Poly ADP ribose polymerase inhibitors (PARPi) are most effective in BRCA1/2 mutated ovarian tumors. Better treatments are needed for homologous recombination HR-proficient cancer, including CCNE1 amplified subtypes. We have shown that histone deacetylase inhibitors (HDACi) sensitize HR-proficient ovarian...

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Gupta VG, Hirst J, Petersen S, et al. Entinostat, a selective HDAC1/2 inhibitor, potentiates the effects of olaparib in homologous recombination proficient ovarian cancer. Gynecol Oncol. 2021;162(1):163-172doi: 10.1016/j.ygyno.2021.04.015.
Gupta, V. G., Hirst, J., Petersen, S., Roby, K. F., Kusch, M., Zhou, H., Clive, M. L., Jewell, A., Pathak, H. B., Godwin, A. K., Wilson, A. J., Crispens, M. A., Cybulla, E., Vindigni, A., Fuh, K. C., & Khabele, D. (2021). Entinostat, a selective HDAC1/2 inhibitor, potentiates the effects of olaparib in homologous recombination proficient ovarian cancer. Gynecologic oncology, 162(1), 163-172. https://doi.org/10.1016/j.ygyno.2021.04.015
Gupta, Vijayalaxmi G, et al. "Entinostat, a selective HDAC1/2 inhibitor, potentiates the effects of olaparib in homologous recombination proficient ovarian cancer." Gynecologic oncology vol. 162,1 (2021): 163-172. doi: https://doi.org/10.1016/j.ygyno.2021.04.015
Gupta VG, Hirst J, Petersen S, Roby KF, Kusch M, Zhou H, Clive ML, Jewell A, Pathak HB, Godwin AK, Wilson AJ, Crispens MA, Cybulla E, Vindigni A, Fuh KC, Khabele D. Entinostat, a selective HDAC1/2 inhibitor, potentiates the effects of olaparib in homologous recombination proficient ovarian cancer. Gynecol Oncol. 2021 Jul;162(1):163-172. doi: 10.1016/j.ygyno.2021.04.015. Epub 2021 Apr 16. PMID: 33867143; PMCID: PMC8647995.
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Showing 337 to 345 of 345 entries