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Showing 241 to 246 of 246 entries
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Is IgA nephropathy the same disease in different parts of the world?.

Seminars in immunopathology

Zhang H, Barratt J.
PMID: 34417628
Semin Immunopathol. 2021 Oct;43(5):707-715. doi: 10.1007/s00281-021-00884-7. Epub 2021 Aug 20.

Since it was first described in 1968, immunoglobulin A nephropathy (IgAN) is understood to be the most common form of glomerulonephritis worldwide. The diagnosis of IgAN depends on the presence of dominant mesangial IgA1 deposition by renal biopsy. To...

What is the role of single-stage oral mucosa graft urethroplasty in the surgical management of lichen sclerosus-related stricture disease in men? A systematic review.

World journal of urology

Esperto F, Verla W, Ploumidis A, Barratt R, La Rocca R, Lumen N, Yuan Y, Campos-Juanatey F, Greenwell T, Martins F, Osman N, Riechardt S, Waterloos M, Dimitropoulos K.
PMID: 34448008
World J Urol. 2021 Aug 26; doi: 10.1007/s00345-021-03803-5. Epub 2021 Aug 26.

PURPOSE: The benefits and harms of the available types of surgical management for lichen sclerosus-related (LS) strictures remain unclear and, thus, clear and robust clinical practice recommendations cannot be given.MATERIALS AND METHODS: To assess the role of single-stage OMGU...

Controlled human malaria infection with a clone of Plasmodium vivax with high-quality genome assembly.

JCI insight

Minassian AM, Themistocleous Y, Silk SE, Barrett JR, Kemp A, Quinkert D, Nielsen CM, Edwards NJ, Rawlinson TA, Ramos Lopez F, Roobsoong W, Ellis KJ, Cho JS, Aunin E, Otto TD, Reid AJ, Bach FA, Labbé GM, Poulton ID, Marini A, Zaric M, Mulatier M, Lopez Ramon R, Baker M, Mitton CH, Sousa JC, Rachaphaew N, Kumpitak C, Maneechai N, Suansomjit C, Piteekan T, Hou MM, Khozoee B, McHugh K, Roberts DJ, Lawrie AM, Blagborough AM, Nugent FL, Taylor IJ, Johnson KJ, Spence PJ, Sattabongkot J, Biswas S, Rayner JC, Draper SJ.
PMID: 34609964
JCI Insight. 2021 Dec 08;6(23). doi: 10.1172/jci.insight.152465.

Controlled human malaria infection (CHMI) provides a highly informative means to investigate host-pathogen interactions and enable in vivo proof-of-concept efficacy testing of new drugs and vaccines. However, unlike Plasmodium falciparum, well-characterized P. vivax parasites that are safe and suitable...

A Focus Group Study of Self-Management in Patients With Glomerular Disease.

Kidney international reports

Carter SA, Teng C, Gutman T, Logeman C, Cattran D, Lightstone L, Bagga A, Barbour SJ, Barratt J, Boletis J, Caster DJ, Coppo R, Fervenza FC, Floege J, Hladunewich MA, Hogan JJ, Kitching AR, Lafayette RA, Malvar A, Radhakrishnan J, Rovin BH, Scholes-Robertson N, Trimarchi H, Zhang H, Azukaitis K, Cho Y, Viecelli AK, Dunn L, Harris D, Johnson DW, Kerr PG, Laboi P, Ryan J, Shen JI, Ruiz L, Wang AY, Lee AHK, Ka Shun SF, Ka-Hang Tong M, Teixeira-Pinto A, Wilkie M, Alexander SI, Craig JC, Martin A, Tong A.
PMID: 35005314
Kidney Int Rep. 2021 Oct 30;7(1):56-67. doi: 10.1016/j.ekir.2021.10.011. eCollection 2022 Jan.

INTRODUCTION: Patients with glomerular disease experience symptoms that impair their physical and mental health while managing their treatments, diet, appointments and monitoring general and specific indicators of health and their illness. We sought to describe the perspectives of patients...

A Pilot Study to Predict Risk of IgA Nephropathy Progression Based on miR-204 Expression.

Kidney international reports

Pawluczyk I, Nicholson M, Barbour S, Er L, Selvaskandan H, Bhachu JS, Barratt J.
PMID: 34386667
Kidney Int Rep. 2021 Jun 05;6(8):2179-2188. doi: 10.1016/j.ekir.2021.05.018. eCollection 2021 Aug.

INTRODUCTION: Immunoglobulin (Ig)A nephropathy (IgAN) is the most frequently diagnosed primary glomerulonephritis worldwide. Despite the common diagnostic feature of mesangial IgA-containing immune complex deposition, the clinical course of the disease is extremely variable, with 30% of patients developing end-stage...

Expansion of chronic MS lesions is associated with an increase of radial diffusivity in periplaque white matter.

Multiple sclerosis (Houndmills, Basingstoke, England)

Klistorner S, Barnett MH, Yiannikas C, Barton J, Parratt J, You Y, Graham SL, Klistorner A.
PMID: 34378454
Mult Scler. 2021 Aug 11;13524585211033464. doi: 10.1177/13524585211033464. Epub 2021 Aug 11.

BACKGROUND: Expansion of chronic multiple sclerosis (MS) lesion is associated with slow-burning inflammation at lesion rim. However, the underlying mechanisms leading to expansion are not fully understood.OBJECTIVE: To investigate the relationship between diffusivity markers of demyelination and axonal loss...

Showing 241 to 246 of 246 entries