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Showing 25 to 36 of 113 entries
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PDGFRA Immunohistochemistry Predicts PDGFRA Mutations in Gastrointestinal Stromal Tumors.

The American journal of surgical pathology

Papke DJ, Forgó E, Charville GW, Hornick JL.
PMID: 33859072
Am J Surg Pathol. 2022 Jan 01;46(1):3-10. doi: 10.1097/PAS.0000000000001720.

Platelet-derived growth factor receptor A (PDGFRA) is a receptor tyrosine kinase that is activated by mutations in 10% of gastrointestinal stromal tumors (GISTs) and 55% to 70% of inflammatory fibroid polyps. PDGFRA-mutant GISTs are usually epithelioid and occur predominantly...

Recent advances in the diagnosis, classification and molecular pathogenesis of cutaneous mesenchymal neoplasms.

Histopathology

Papke DJ, Hornick JL.
PMID: 34958499
Histopathology. 2022 Jan;80(1):216-232. doi: 10.1111/his.14450.

The diagnosis of cutaneous mesenchymal neoplasms remains challenging, due to a combination of overlapping histological features, the rarity of some diagnoses and often inadequate sampling in superficial biopsies. Here, we describe recent advances in cutaneous mesenchymal neoplasms. We discuss...

A pilot randomised controlled trial of a structured, home-based exercise programme on cardiovascular structure and function in kidney transplant recipients: the ECSERT study design and methods.

BMJ open

Billany RE, Vadaszy N, Bishop NC, Wilkinson TJ, Adenwalla SF, Robinson KA, Croker K, Brady EM, Wormleighton JV, Parke KS, Cooper NJ, Webster AC, Barratt J, McCann GP, Burton JO, Smith AC, Graham-Brown MP.
PMID: 34610929
BMJ Open. 2021 Oct 05;11(10):e046945. doi: 10.1136/bmjopen-2020-046945.

BACKGROUND: Cardiovascular disease (CVD) is a major cause of morbidity and mortality in kidney transplant recipients (KTRs). CVD risk scores underestimate risk in this population as CVD is driven by clustering of traditional and non-traditional risk factors, which lead...

Measuring and Mattering.

Missouri medicine

Parke DW.
PMID: 30228525
Mo Med. 2016 Nov-Dec;113(6):448.

No abstract available.

A cautionary note for claims about the microbiome's impact on the "self".

PLoS biology

Parke EC, Calcott B, O'Malley MA.
PMID: 30208018
PLoS Biol. 2018 Sep 12;16(9):e2006654. doi: 10.1371/journal.pbio.2006654. eCollection 2018 Sep.

No abstract available.

Fast Data Sorting with Modified Principal Component Analysis to Distinguish Unique Single Molecular Break Junction Trajectories.

Physical review letters

Hamill JM, Zhao XT, Mészáros G, Bryce MR, Arenz M, Pinnock H, Parke HL, Panagioti M.
PMID: 29350952
Phys Rev Lett. 2018 Jan 05;120(1):016601. doi: 10.1103/PhysRevLett.120.016601.

A simple and fast analysis method to sort large data sets into groups with shared distinguishing characteristics is described and applied to single molecular break junction conductance versus electrode displacement data. The method, based on principal component analysis, successfully...

Phytophthora-ID.org: A Sequence-Based Phytophthora Identification Tool.

Plant disease

Grünwald NJ, Martin FN, Larsen MM, Sullivan CM, Press CM, Coffey MD, Hansen EM, Parke JL.
PMID: 30743500
Plant Dis. 2011 Mar;95(3):337-342. doi: 10.1094/PDIS-08-10-0609.

Contemporary species identification relies strongly on sequence-based identification, yet resources for identification of many fungal and oomycete pathogens are rare. We developed two web-based, searchable databases for rapid identification of Phytophthora spp. based on sequencing of the internal transcribed...

Seasat altimeter calibration: initial results.

Science (New York, N.Y.)

Tapley BD, Born GH, Hagar HH, Lorell J, Parke ME, Diamante JM, Douglas BC, Goad CC, Kolenkiewicz R, Marsh JG, Martin CF, Smith SL, Townsend WF, Whitehead JA, Byrne HM, Fedor LS, Hammond DC, Mognard NM.
PMID: 17814198
Science. 1979 Jun 29;204(4400):1410-2. doi: 10.1126/science.204.4400.1410.

Preliminary analysis of radar altimeter data indicates that the instrument has met its specifications for measuring spacecraft height above the ocean surface (+/- 10 centimeters) and significant wave height (+/- 0.5 meter). There is ample evidence that the radar...

Computer modelling and in vitro tests in the safety evaluation of chemicals-Strategic applications.

Toxicology in vitro : an international journal published in association with BIBRA

Parke DV, Ioannides C, Lewis DF.
PMID: 20702255
Toxicol In Vitro. 1990;4(4):680-5. doi: 10.1016/0887-2333(90)90141-f.

The cytochromes P-450 detoxicate most chemicals, but activate carcinogens and other toxic chemicals by oxygenating them to reactive intermediates. A new strategy based on the P-450s has resulted in the development of a computer program (COMPACT) and of a...

An unusually large granular cell tumor of the pharynx: a case report and literature review.

International journal of clinical and experimental pathology

Li X, Parke RB, Rushton JR, Sienko A, Zhai QJ.
PMID: 19079624
Int J Clin Exp Pathol. 2009;2(3):300-2. Epub 2008 Oct 01.

We report a granular cell tumor of the pharynx in a 53 year-old woman who presented with a large retropharyngeal mass. Surgical excision revealed a 5.5 cm tan rubbery unencapsulated but circumscribed mass. Histologically, the tumor is composed of...

Sjögren's syndrome: History, clinical and pathological features.

Inflammopharmacology

Parke AL, Buchanan WW.
PMID: 17657625
Inflammopharmacology. 1998;6(4):271-87. doi: 10.1007/s10787-998-0012-6.

The history, ocular and oral clinical features, and histopathology of Sjögren's syndrome are described. Primary Sjögren's syndrome is defined when only the ocular and oral components are present, while the secondary form refers to the association with a connective...

Social and ethical checkpoints for bottom-up synthetic biology, or protocells.

Systems and synthetic biology

Bedau MA, Parke EC, Tangen U, Hantsche-Tangen B.
PMID: 19816801
Syst Synth Biol. 2009 Dec;3(1):65-75. doi: 10.1007/s11693-009-9039-2. Epub 2009 Oct 10.

An alternative to creating novel organisms through the traditional "top-down" approach to synthetic biology involves creating them from the "bottom up" by assembling them from non-living components; the products of this approach are called "protocells." In this paper we...

Showing 25 to 36 of 113 entries