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Showing 13 to 24 of 356 entries
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Are AMPA receptor positive allosteric modulators potential pharmacotherapeutics for addiction?.

Pharmaceuticals (Basel, Switzerland)

Watterson LR, Olive MF.
PMID: 24380895
Pharmaceuticals (Basel). 2013 Dec 30;7(1):29-45. doi: 10.3390/ph7010029.

Positive allosteric modulators (PAMs) of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are a diverse class of compounds that increase fast excitatory transmission in the brain. AMPA PAMs have been shown to facilitate long-term potentiation, strengthen communication between various cortical and subcortical...

A multifactorial anti-cachectic approach for cancer cachexia in a rat model undergoing chemotherapy.

Journal of cachexia, sarcopenia and muscle

Toledo M, Penna F, Oliva F, Luque M, Betancourt A, Marmonti E, López-Soriano FJ, Argilés JM, Busquets S.
PMID: 27066318
J Cachexia Sarcopenia Muscle. 2016 Mar;7(1):48-59. doi: 10.1002/jcsm.12035. Epub 2015 May 14.

BACKGROUND: The effectiveness of drugs aimed at counteracting cancer cachexia is generally tested in pre-clinical rodent models, where only the tumour-induced alterations are taken into account, excluding the co-presence of anti-tumour molecules that could worsen the scenario and/or interfere...

Biological properties of mesenchymal Stem Cells from different sources.

Muscles, ligaments and tendons journal

Via AG, Frizziero A, Oliva F.
PMID: 23738292
Muscles Ligaments Tendons J. 2012 Oct 16;2(3):154-62. Print 2012 Jul.

Mesenchymal stem cells (MSCs) are adult, nonhematopoietic, stem cells that were initially isolated from bone marrow. Now they can be isolated from almost every tissue of the body. They have the ability to self-renew and differentiate into multiple cell...

Sensitization to the motor stimulant effects of 3,4-methylenedioxypyrovalerone (MDPV) and cross-sensitization to methamphetamine in rats.

Journal of drug and alcohol research

Watterson LR, Kufahl PR, Taylor SB, Nemirovsky NE, Olive MF.
PMID: 27284493
J Drug Alcohol Res. 2016 May;5. doi: 10.4303/jdar/235967.

BACKGROUND: In recent years, there has been a dramatic increase in abuse of the synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV), often in combination with other illicit stimulants.PURPOSE: We sought to determine if repeated exposure to MDPV would produce sensitization to the...

[The borderlines between classical tuberculosis and atypical tuberculoses].

La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris

JACQUELIN A, GRATAY A, OLIVO HR, CHIRON JP, SCHWARTZ B.
PMID: 13789094
Sem Hop. 1961 Apr 20;37:1315-20.

No abstract available.

Computed tomography imaging of subpleural lipoma in two men: two case reports.

Journal of medical case reports

Karlo CA, Stolzmann P, Frauenfelder T, Donati OF, Leschka S.
PMID: 21108781
J Med Case Rep. 2010 Nov 25;4:380. doi: 10.1186/1752-1947-4-380.

INTRODUCTION: Subpleural lipomas are very rare pleural lesions and are often discovered incidentally in asymptomatic patients on conventional radiographs.CASE PRESENTATIONS: We report two cases of subpleural lipomas and describe their imaging characteristics on chest radiographs and computed tomography. We...

Investigating Methamphetamine Craving Using the Extinction-Reinstatement Model in the Rat.

Journal of addiction research & therapy

Kufahl PR, Olive MF.
PMID: 22428089
J Addict Res Ther. 2011 Nov 15;(3). doi: 10.4172/2155-6105.s1-003.

Like all other drugs of abuse, the primary therapeutic objective for treating methamphetamine addiction research is the maintenance of abstinence and prevention of relapse to habitual drug-taking. Compounds with the potential to prevent relapse are often investigated in rats...

The mGluR5 Positive Allosteric Modulator CDPPB Does Not Alter Extinction or Contextual Reinstatement of Methamphetamine-Seeking Behavior in Rats.

Journal of addiction research & therapy

Widholm JJ, Gass JT, Cleva RM, Olive MF.
PMID: 22428090
J Addict Res Ther. 2011 Dec 24;(4). doi: 10.4172/2155-6105.S1-004.

Extinction of drug-seeking behavior is a form of new and active learning. Facilitation of extinction learning is of clinical interest since cue exposure therapies for the treatment of addiction have largely been unsuccessful in preventing relapse, primarily due to...

Positive or negative allosteric modulation of metabotropic glutamate receptor 5 (mGluR5) does not alter expression of behavioral sensitization to methamphetamine.

F1000Research

Kufahl PR, Nemirovsky NE, Watterson LR, Zautra N, Olive MF.
PMID: 24358885
F1000Res. 2013 Mar 12;2:84. doi: 10.12688/f1000research.2-84.v1. eCollection 2013.

We investigated the role of metabotropic glutamate receptor type 5 (mGluR5) in methamphetamine-induced behavioral sensitization. The mGluR5 positive allosteric modulator (3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl) benzamide (CDPPB) and negative allosteric modulator fenobam were tested in separate experiments. Sprague-Dawley rats were repeatedly injected with...

Clinical and biological aspects of rotator cuff tears.

Muscles, ligaments and tendons journal

Via AG, De Cupis M, Spoliti M, Oliva F.
PMID: 23888289
Muscles Ligaments Tendons J. 2013 Jul 09;3(2):70-9. doi: 10.11138/mltj/2013.3.2.070. Print 2013 Apr.

Rotator cuff tears are common and are a frequent source of shoulder pain and disability. A wide variation in the prevalence of rotator cuff tears has been reported. The etiology of rotator cuff tear remains multifactorial and attempts to...

Search for a dark matter annihilation signal from the galactic center halo with H.E.S.S.

Physical review letters

Abramowski A, Acero F, Aharonian F, Akhperjanian AG, Anton G, Barnacka A, de Almeida UB, Bazer-Bachi AR, Becherini Y, Becker J, Behera B, Bernlöhr K, Bochow A, Boisson C, Bolmont J, Bordas P, Borrel V, Brucker J, Brun F, Brun P, Bulik T, Büsching I, Carrigan S, Casanova S, Cerruti M, Chadwick PM, Charbonnier A, Chaves RC, Cheesebrough A, Chounet LM, Clapson AC, Coignet G, Conrad J, Dalton M, Daniel MK, Davids ID, Degrange B, Deil C, Dickinson HJ, Djannati-Ataï A, Domainko W, Drury LO, Dubois F, Dubus G, Dyks J, Dyrda M, Egberts K, Eger P, Espigat P, Fallon L, Farnier C, Fegan S, Feinstein F, Fernandes MV, Fiasson A, Fontaine G, Förster A, Füssling M, Gallant YA, Gast H, Gérard L, Gerbig D, Giebels B, Glicenstein JF, Glück B, Goret P, Göring D, Hague JD, Hampf D, Hauser M, Heinz S, Heinzelmann G, Henri G, Hermann G, Hinton JA, Hoffmann A, Hofmann W, Hofverberg P, Horns D, Jacholkowska A, de Jager OC, Jahn C, Jamrozy M, Jung I, Kastendieck MA, Katarzyński K, Katz U, Kaufmann S, Keogh D, Kerschhaggl M, Khangulyan D, Khélifi B, Klochkov D, Kluźniak W, Kneiske T, Komin N, Kosack K, Kossakowski R, Laffon H, Lamanna G, Lennarz D, Lohse T, Lopatin A, Lu CC, Marandon V, Marcowith A, Masbou J, Maurin D, Maxted N, McComb TJ, Medina MC, Méhault J, Moderski R, Moulin E, Naumann CL, Naumann-Godo M, de Naurois M, Nedbal D, Nekrassov D, Nguyen N, Nicholas B, Niemiec J, Nolan SJ, Ohm S, Olive JF, Wilhelmi Ede O, Opitz B, Ostrowski M, Panter M, Arribas MP, Pedaletti G, Pelletier G, Petrucci PO, Pita S, Pühlhofer G, Punch M, Quirrenbach A, Raue M, Rayner SM, Reimer A, Reimer O, Renaud M, de los Reyes R, Rieger F, Ripken J, Rob L, Rosier-Lees S, Rowell G, Rudak B, Rulten CB, Ruppel J, Ryde F, Sahakian V, Santangelo A, Schlickeiser R, Schöck FM, Schönwald A, Schwanke U, Schwarzburg S, Schwemmer S, Shalchi A, Sikora M, Skilton JL, Sol H, Spengler G, Stawarz Ł, Steenkamp R, Stegmann C, Stinzing F, Sushch I, Szostek A, Tavernet JP, Terrier R, Tibolla O, Tluczykont M, Valerius K, van Eldik C, Vasileiadis G, Venter C, Vialle JP, Viana A, Vincent P, Vivier M, Völk HJ, Volpe F, Vorobiov S, Vorster M, Wagner SJ, Ward M, Wierzcholska A, Zajczyk A, Zdziarski AA, Zech A, Zechlin HS.
PMID: 21599352
Phys Rev Lett. 2011 Apr 22;106(16):161301. doi: 10.1103/PhysRevLett.106.161301. Epub 2011 Apr 18.

A search for a very-high-energy (VHE; ≥100  GeV) γ-ray signal from self-annihilating particle dark matter (DM) is performed towards a region of projected distance r∼45-150  pc from the Galactic center. The background-subtracted γ-ray spectrum measured with the High Energy...

ISMuLT Guidelines for muscle injuries.

Muscles, ligaments and tendons journal

Maffulli N, Oliva F, Frizziero A, Nanni G, Barazzuol M, Via AG, Ramponi C, Brancaccio P, Lisitano G, Rizzo D, Freschi M, Galletti S, Melegati G, Pasta G, Testa V, Valent A, Del Buono A.
PMID: 24596685
Muscles Ligaments Tendons J. 2014 Feb 24;3(4):241-9. eCollection 2013 Oct.

Muscle injuries are frequent in high demand sports. No guidelines are available in the scientific literature. ISMuLT, the "Italian Society of Muscles, Ligaments and Tendons", in line with its multidisciplinary mission, is proud to cover this gap.

Showing 13 to 24 of 356 entries