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Showing 37 to 48 of 289 entries
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Trends in Outcomes for Marginal Allografts in Liver Transplant.

JAMA surgery

Zhang T, Dunson J, Kanwal F, Galvan NTN, Vierling JM, O'Mahony C, Goss JA, Rana A.
PMID: 32936250
JAMA Surg. 2020 Aug 05; doi: 10.1001/jamasurg.2020.2484. Epub 2020 Aug 05.

IMPORTANCE: Investigating outcomes after marginal allograft transplant is essential in determining appropriate and more aggressive use of these allografts.OBJECTIVE: To determine the time trends in the outcomes of marginal liver allografts as defined by 6 different sets of criteria.DESIGN,...

Association of Left Ventricular Systolic Dysfunction Among Carriers of Truncating Variants in Filamin C With Frequent Ventricular Arrhythmia and End-stage Heart Failure.

JAMA cardiology

Akhtar MM, Lorenzini M, Pavlou M, Ochoa JP, O'Mahony C, Restrepo-Cordoba MA, Segura-Rodriguez D, Bermúdez-Jiménez F, Molina P, Cuenca S, Ader F, Larrañaga-Moreira JM, Sabater-Molina M, Garcia-Alvarez MI, Arantzamendi LG, Truszkowska G, Ortiz-Genga M, Ruiz IS, Nielsen SK, Rasmussen TB, Robles Mezcua A, Alvarez-Rubio J, Eiskjaer H, Gautel M, Garcia-Pinilla JM, Ripoll-Vera T, Mogensen J, Limeres Freire J, Rodríguez-Palomares JF, Peña-Peña ML, Rangel-Sousa D, Palomino-Doza J, Arana Achaga X, Bilinska Z, Zamarreño Golvano E, Climent V, Peñalver MN, Barriales-Villa R, Charron P, Yotti R, Zorio E, Jiménez-Jáimez J, Garcia-Pavia P, Elliott PM.
PMID: 33978673
JAMA Cardiol. 2021 Aug 01;6(8):891-901. doi: 10.1001/jamacardio.2021.1106.

IMPORTANCE: Truncating variants in the gene encoding filamin C (FLNCtv) are associated with arrhythmogenic and dilated cardiomyopathies with a reportedly high risk of ventricular arrhythmia.OBJECTIVE: To determine the frequency of and risk factors associated with adverse events among FLNCtv...

Cross-sectional study on the prevalence of influenza and pneumococcal vaccination and its association with health conditions and risk factors among hospitalized multimorbid older patients.

PloS one

Papazoglou DD, Baretella O, Feller M, Del Giovane C, Moutzouri E, Aujesky D, Schwenkglenks M, O'Mahony D, Knol W, Dalleur O, Rodondi N, Baumgartner C.
PMID: 34784405
PLoS One. 2021 Nov 16;16(11):e0260112. doi: 10.1371/journal.pone.0260112. eCollection 2021.

BACKGROUND: Older adults with chronic conditions are at high risk of complications from influenza and pneumococcal infections. Evidence about factors associated with influenza and pneumococcal vaccination among older multimorbid persons in Europe is limited. The aim of this study...

Should we use dabigatran or aspirin thromboprophylaxis in total hip and knee arthroplasty? A natural experiment.

Journal of orthopaedics

McHale S, Williams M, O'Mahony C, Hockings M.
PMID: 31660024
J Orthop. 2019 May 27;16(6):563-568. doi: 10.1016/j.jor.2019.05.008. eCollection 2019.

BACKGROUND: Despite long clinical experience some authorities recommend against the use of aspirin for perioperative VTE prophylaxis and favour alternatives such as dabigatran. A change from Dabigatran to an Aspirin based protocol in a British district general hospital created...

Practice Improvement Projects in an Interdisciplinary Palliative Care Training Program.

The American journal of hospice & palliative care

Ansari A, Baron A, Nelson-Becker H, Deamant C, Fitchett G, Fister E, O'Mahony S, Levine S.
PMID: 34490785
Am J Hosp Palliat Care. 2021 Sep 07;10499091211044689. doi: 10.1177/10499091211044689. Epub 2021 Sep 07.

CONTEXT: Demand for palliative care (PC) continues to increase with an insufficient number of specialists to meet the need. This requires implementation of training curricula to expand the workforce of interdisciplinary clinicians who care for persons with serious illness.OBJECTIVES:...

Screening for obstructive sleep apnea with novel hybrid acoustic smartphone app technology.

Journal of thoracic disease

Tiron R, Lyon G, Kilroy H, Osman A, Kelly N, O'Mahony N, Lopes C, Coffey S, McMahon S, Wren M, Conway K, Fox N, Costello J, Shouldice R, Lederer K, Fietze I, Penzel T.
PMID: 32944361
J Thorac Dis. 2020 Aug;12(8):4476-4495. doi: 10.21037/jtd-20-804.

BACKGROUND: Obstructive sleep apnea (OSA) has a high prevalence, with an estimated 425 million adults with apnea hypopnea index (AHI) of ≥15 events/hour, and is significantly underdiagnosed. This presents a significant pain point for both the sufferers, and for...

Knowledge and attitudes of Irish GPs towards abortion following its legalisation: a cross-sectional study.

BJGP open

O'Connor R, O'Doherty J, O'Mahony M, Spain E.
PMID: 31822491
BJGP Open. 2019 Dec 10; doi: 10.3399/bjgpopen19X101669. Epub 2019 Dec 10.

BACKGROUND: In May 2018, the Irish Constitution was changed following a referendum allowing termination of pregnancy by abortion. It is envisaged that the majority of terminations will be by medical abortion and will take place in general practice before...

Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories.

bioRxiv : the preprint server for biology

Su Y, Chen D, Lausted C, Yuan D, Choi J, Dai C, Voillet V, Scherler K, Troisch P, Duvvuri VR, Baloni P, Qin G, Smith B, Kornilov S, Rostomily C, Xu A, Li J, Dong S, Rothchild A, Zhou J, Murray K, Edmark R, Hong S, Jones L, Zhou Y, Roper R, Mackay S, O'Mahony DS, Dale CR, Wallick JA, Algren HA, Michael ZA, Magis A, Wei W, Price ND, Huang S, Subramanian N, Wang K, Hadlock J, Hood L, Aderem A, Bluestone JA, Lanier LL, Greenberg P, Gottardo R, Davis MM, Goldman JD, Heath JR.
PMID: 32766585
bioRxiv. 2020 Jul 31; doi: 10.1101/2020.07.27.224063.

Host immune responses play central roles in controlling SARS-CoV2 infection, yet remain incompletely characterized and understood. Here, we present a comprehensive immune response map spanning 454 proteins and 847 metabolites in plasma integrated with single-cell multi-omic assays of PBMCs...

Signal Detection in EUROmediCAT: Identification and Evaluation of Medication-Congenital Anomaly Associations and Use of VigiBase as a Complementary Source of Reference.

Drug safety

Cavadino A, Sandberg L, Öhman I, Bergvall T, Star K, Dolk H, Loane M, Addor MC, Barisic I, Cavero-Carbonell C, Garne E, Gatt M, Khoshnood B, Klungsøyr K, Latos-Bielenska A, Lelong N, Lutke R, Materna-Kiryluk A, Nelen V, Nevill A, O'Mahony M, Mokoroa O, Pierini A, Randrianaivo H, Rissmann A, Tucker D, Wiesel A, Yevtushok L, Morris JK.
PMID: 33966183
Drug Saf. 2021 Jul;44(7):765-785. doi: 10.1007/s40264-021-01073-z. Epub 2021 May 09.

INTRODUCTION: Knowledge on the safety of medication use during pregnancy is often sparse. Pregnant women are generally excluded from clinical trials, and there is a dependence on post-marketing surveillance to identify teratogenic medications.AIMS: This study aimed to identify signals...

Late-Onset Tay-Sachs Disease in an Irish Family.

Movement disorders clinical practice

Lefter S, O' Mahony O, Sweeney B, Ryan AM.
PMID: 33426165
Mov Disord Clin Pract. 2020 Oct 28;8(1):106-110. doi: 10.1002/mdc3.13096. eCollection 2021 Jan.

BACKGROUND: Late-onset Tay-Sachs disease (LOTS) is an autosomal-recessive lysosomal storage disease caused by deficient β-hexosaminidase A activity. LOTS is rare in the Ashkenazi Jews, but even rarer in the non-Jewish population.CASES: We report an Irish family expanding the LOTS...

Lymphangioleiomyomatosis: a clinical review.

Breathe (Sheffield, England)

O'Mahony AM, Lynn E, Murphy DJ, Fabre A, McCarthy C.
PMID: 33304400
Breathe (Sheff). 2020 Jun;16(2):200007. doi: 10.1183/20734735.0007-2020.

Lymphangioleiomyomatosis (LAM) is a diffuse cystic lung disease. There are two main types of LAM: sporadic, and LAM associated with the tuberous sclerosis complex (TSC), which is caused by mutations in the EDUCATIONAL AIMS: To illustrate the clinical features,...

Recycling of aluminium laminated pouches and Tetra Pak cartons by molten metal pyrolysis - Pilot-scale experiments and economic analysis.

Waste management (New York, N.Y.)

Riedewald F, Wilson E, Patel Y, Vogt D, Povey I, Barton K, Lewis L, Caris T, Santos S, O'Mahoney M, Sousa-Gallagher M.
PMID: 34896737
Waste Manag. 2021 Dec 09;138:172-179. doi: 10.1016/j.wasman.2021.11.049. Epub 2021 Dec 09.

Aluminium laminated (AL) pouch packages and aluminium laminated Tetra-Pak cartons are considered unrecyclable, reducing their otherwise excellent lifecycle performance. This paper describes experimental results on pilot plant trials to recycle AL packages with a molten metal pyrolysis reactor. The...

Showing 37 to 48 of 289 entries