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PCN Art Brut Series No. 22, Artwork Description.

Psychiatry and clinical neurosciences

Hosaka K.
PMID: 34355477
Psychiatry Clin Neurosci. 2021 Aug;75(8):271. doi: 10.1111/pcn.13280.

No abstract available.

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Hosaka K. PCN Art Brut Series No. 22, Artwork Description. Psychiatry Clin Neurosci. 2021;75(8):271doi: 10.1111/pcn.13280.
Hosaka, K. (2021). PCN Art Brut Series No. 22, Artwork Description. Psychiatry and clinical neurosciences, 75(8), 271. https://doi.org/10.1111/pcn.13280
Hosaka, Kenjiro. "PCN Art Brut Series No. 22, Artwork Description." Psychiatry and clinical neurosciences vol. 75,8 (2021): 271. doi: https://doi.org/10.1111/pcn.13280
Hosaka K. PCN Art Brut Series No. 22, Artwork Description. Psychiatry Clin Neurosci. 2021 Aug;75(8):271. doi: 10.1111/pcn.13280. PMID: 34355477.
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Understanding the genetics of intracranial aneurysms: A primer.

Clinical neurology and neurosurgery

Laurent D, Small C, Lucke-Wold B, Dodd WS, Chalouhi N, Hu YC, Hosaka K, Motwani K, Martinez M, Polifka A, Koch M, Busl KM, Maciel CB, Hoh B.
PMID: 34863053
Clin Neurol Neurosurg. 2021 Nov 25;212:107060. doi: 10.1016/j.clineuro.2021.107060. Epub 2021 Nov 25.

The genetics of intracranial aneurysms is complex. Much work has been done looking at the extracellular matrix surrounding cerebral vasculature as well as the role of matrix metalloproteinases. This comprehensive review summarizes what is known to date about the...

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Laurent D, Small C, Lucke-Wold B, et al. Understanding the genetics of intracranial aneurysms: A primer. Clin Neurol Neurosurg. 2021;212:107060doi: 10.1016/j.clineuro.2021.107060.
Laurent, D., Small, C., Lucke-Wold, B., Dodd, W. S., Chalouhi, N., Hu, Y. C., Hosaka, K., Motwani, K., Martinez, M., Polifka, A., Koch, M., Busl, K. M., Maciel, C. B., & Hoh, B. (2021). Understanding the genetics of intracranial aneurysms: A primer. Clinical neurology and neurosurgery, 212107060. https://doi.org/10.1016/j.clineuro.2021.107060
Laurent, Dimitri, et al. "Understanding the genetics of intracranial aneurysms: A primer." Clinical neurology and neurosurgery vol. 212 (2021): 107060. doi: https://doi.org/10.1016/j.clineuro.2021.107060
Laurent D, Small C, Lucke-Wold B, Dodd WS, Chalouhi N, Hu YC, Hosaka K, Motwani K, Martinez M, Polifka A, Koch M, Busl KM, Maciel CB, Hoh B. Understanding the genetics of intracranial aneurysms: A primer. Clin Neurol Neurosurg. 2021 Nov 25;212:107060. doi: 10.1016/j.clineuro.2021.107060. Epub 2021 Nov 25. PMID: 34863053.
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The Usefulness of a Simple Classification for Bronchoscopic Findings for Diagnosis of Peripheral Pulmonary Tumour.

Respiration; international review of thoracic diseases

Fukada T, Morita K, Kurimoto N, Setoguchi M, Nosaka S, Katsumata T.
PMID: 33839728
Respiration. 2021;100(8):794-803. doi: 10.1159/000515183. Epub 2021 Apr 09.

BACKGROUND: Normal bronchial epithelium has been described in terms of transparency and smoothness. No studies have compared bronchoscopic and pathological findings in the identification of bronchial epithelium.OBJECTIVES: This study aimed to classify bronchoscopic findings for peripheral pulmonary tumour (PPT)...

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Fukada T, Morita K, Kurimoto N, et al. The Usefulness of a Simple Classification for Bronchoscopic Findings for Diagnosis of Peripheral Pulmonary Tumour. Respiration. 2021;100(8):794-803doi: 10.1159/000515183.
Fukada, T., Morita, K., Kurimoto, N., Setoguchi, M., Nosaka, S., & Katsumata, T. (2021). The Usefulness of a Simple Classification for Bronchoscopic Findings for Diagnosis of Peripheral Pulmonary Tumour. Respiration; international review of thoracic diseases, 100(8), 794-803. https://doi.org/10.1159/000515183
Fukada, Takehisa, et al. "The Usefulness of a Simple Classification for Bronchoscopic Findings for Diagnosis of Peripheral Pulmonary Tumour." Respiration; international review of thoracic diseases vol. 100,8 (2021): 794-803. doi: https://doi.org/10.1159/000515183
Fukada T, Morita K, Kurimoto N, Setoguchi M, Nosaka S, Katsumata T. The Usefulness of a Simple Classification for Bronchoscopic Findings for Diagnosis of Peripheral Pulmonary Tumour. Respiration. 2021;100(8):794-803. doi: 10.1159/000515183. Epub 2021 Apr 09. PMID: 33839728.
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Clinical features as potential prognostic factors in patients treated with nivolumab for highly pretreated metastatic gastric cancer: a multicenter retrospective study.

BMC cancer

Sano A, Sohda M, Nakazawa N, Ubukata Y, Kuriyama K, Kimura A, Kogure N, Hosaka H, Naganuma A, Sekiguchi M, Saito K, Ogata K, Sakai M, Ogawa H, Shirabe K, Saeki H.
PMID: 34980017
BMC Cancer. 2022 Jan 03;22(1):22. doi: 10.1186/s12885-021-09118-3.

BACKGROUND: Although nivolumab (anti-programmed cell death-1 antibody) is a promising approach for advanced gastric cancer (AGC), the response rate remains limited. The aim of this multicenter retrospective study was to determine if clinical features could serve as prognostic factors...

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Sano A, Sohda M, Nakazawa N, et al. Clinical features as potential prognostic factors in patients treated with nivolumab for highly pretreated metastatic gastric cancer: a multicenter retrospective study. BMC Cancer. 2022;22(1):22doi: 10.1186/s12885-021-09118-3.
Sano, A., Sohda, M., Nakazawa, N., Ubukata, Y., Kuriyama, K., Kimura, A., Kogure, N., Hosaka, H., Naganuma, A., Sekiguchi, M., Saito, K., Ogata, K., Sakai, M., Ogawa, H., Shirabe, K., & Saeki, H. (2022). Clinical features as potential prognostic factors in patients treated with nivolumab for highly pretreated metastatic gastric cancer: a multicenter retrospective study. BMC cancer, 22(1), 22. https://doi.org/10.1186/s12885-021-09118-3
Sano, Akihiko, et al. "Clinical features as potential prognostic factors in patients treated with nivolumab for highly pretreated metastatic gastric cancer: a multicenter retrospective study." BMC cancer vol. 22,1 (2022): 22. doi: https://doi.org/10.1186/s12885-021-09118-3
Sano A, Sohda M, Nakazawa N, Ubukata Y, Kuriyama K, Kimura A, Kogure N, Hosaka H, Naganuma A, Sekiguchi M, Saito K, Ogata K, Sakai M, Ogawa H, Shirabe K, Saeki H. Clinical features as potential prognostic factors in patients treated with nivolumab for highly pretreated metastatic gastric cancer: a multicenter retrospective study. BMC Cancer. 2022 Jan 03;22(1):22. doi: 10.1186/s12885-021-09118-3. PMID: 34980017; PMCID: PMC8721909.
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CT and MR imaging findings of bilateral ovarian metastasis from renal cell carcinoma: a case report.

Acta radiologica open

Fujii S, Mukuda N, Murakami A, Yunaga H, Kitao S, Miyoshi H, Nosaka K.
PMID: 33628461
Acta Radiol Open. 2021 Feb 11;10(2):2058460121990293. doi: 10.1177/2058460121990293. eCollection 2021 Feb.

Secondary ovarian involvement by renal cell carcinoma rarely occurs. Here, we describe the computed tomography and magnetic resonance imaging findings of bilateral ovarian metastases from renal cell carcinoma that demonstrated heterogeneous strong contrast enhancing tumors with flow voids around...

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Fujii S, Mukuda N, Murakami A, et al. CT and MR imaging findings of bilateral ovarian metastasis from renal cell carcinoma: a case report. Acta Radiol Open. 2021;10(2):2058460121990293doi: 10.1177/2058460121990293.
Fujii, S., Mukuda, N., Murakami, A., Yunaga, H., Kitao, S., Miyoshi, H., & Nosaka, K. (2021). CT and MR imaging findings of bilateral ovarian metastasis from renal cell carcinoma: a case report. Acta radiologica open, 10(2), 2058460121990293. https://doi.org/10.1177/2058460121990293
Fujii, Shinya, et al. "CT and MR imaging findings of bilateral ovarian metastasis from renal cell carcinoma: a case report." Acta radiologica open vol. 10,2 (2021): 2058460121990293. doi: https://doi.org/10.1177/2058460121990293
Fujii S, Mukuda N, Murakami A, Yunaga H, Kitao S, Miyoshi H, Nosaka K. CT and MR imaging findings of bilateral ovarian metastasis from renal cell carcinoma: a case report. Acta Radiol Open. 2021 Feb 11;10(2):2058460121990293. doi: 10.1177/2058460121990293. eCollection 2021 Feb. PMID: 33628461; PMCID: PMC7883165.
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Increases in Integrin-ILK-RICTOR-Akt Proteins, Muscle Mass, and Strength after Eccentric Cycling Training.

Medicine and science in sports and exercise

Mavropalias G, Wu YF, Boppart MD, Blazevich AJ, Nosaka K.
PMID: 34468415
Med Sci Sports Exerc. 2022 Jan 01;54(1):89-97. doi: 10.1249/MSS.0000000000002778.

PURPOSE: Recently, it has been suggested that a cellular pathway composed of integrin, integrin-linked kinase (ILK), rapamycin-insensitive companion of mTOR (RICTOR), and Akt may facilitate long-term structural and functional adaptations associated with exercise, independent of the mTORC1 pathway. Therefore,...

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Mavropalias G, Wu YF, Boppart MD, et al. Increases in Integrin-ILK-RICTOR-Akt Proteins, Muscle Mass, and Strength after Eccentric Cycling Training. Med Sci Sports Exerc. 2022;54(1):89-97doi: 10.1249/MSS.0000000000002778.
Mavropalias, G., Wu, Y. F., Boppart, M. D., Blazevich, A. J., & Nosaka, K. (2022). Increases in Integrin-ILK-RICTOR-Akt Proteins, Muscle Mass, and Strength after Eccentric Cycling Training. Medicine and science in sports and exercise, 54(1), 89-97. https://doi.org/10.1249/MSS.0000000000002778
Mavropalias, Georgios, et al. "Increases in Integrin-ILK-RICTOR-Akt Proteins, Muscle Mass, and Strength after Eccentric Cycling Training." Medicine and science in sports and exercise vol. 54,1 (2022): 89-97. doi: https://doi.org/10.1249/MSS.0000000000002778
Mavropalias G, Wu YF, Boppart MD, Blazevich AJ, Nosaka K. Increases in Integrin-ILK-RICTOR-Akt Proteins, Muscle Mass, and Strength after Eccentric Cycling Training. Med Sci Sports Exerc. 2022 Jan 01;54(1):89-97. doi: 10.1249/MSS.0000000000002778. PMID: 34468415.
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Enzymatic Synthesis and Structural Confirmation of Novel Oligosaccharide, D-Fructofuranose-linked Chitin Oligosaccharide.

Journal of applied glycoscience

Hosaka H, Shirai S, Fujita S, Tashiro M, Hirano T, Hakamata W, Nishio T.
PMID: 34354539
J Appl Glycosci (1999). 2020 Nov 20;67(4):129-135. doi: 10.5458/jag.jag.JAG-2020_0009. eCollection 2020.

Utilizing transglycosylation reaction catalyzed by β-

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Hosaka H, Shirai S, Fujita S, et al. Enzymatic Synthesis and Structural Confirmation of Novel Oligosaccharide, D-Fructofuranose-linked Chitin Oligosaccharide. J Appl Glycosci (1999). 2020;67(4):129-135doi: 10.5458/jag.jag.JAG-2020_0009.
Hosaka, H., Shirai, S., Fujita, S., Tashiro, M., Hirano, T., Hakamata, W., & Nishio, T. (2020). Enzymatic Synthesis and Structural Confirmation of Novel Oligosaccharide, D-Fructofuranose-linked Chitin Oligosaccharide. Journal of applied glycoscience, 67(4), 129-135. https://doi.org/10.5458/jag.jag.JAG-2020_0009
Hosaka, Hiroki, et al. "Enzymatic Synthesis and Structural Confirmation of Novel Oligosaccharide, D-Fructofuranose-linked Chitin Oligosaccharide." Journal of applied glycoscience vol. 67,4 (2020): 129-135. doi: https://doi.org/10.5458/jag.jag.JAG-2020_0009
Hosaka H, Shirai S, Fujita S, Tashiro M, Hirano T, Hakamata W, Nishio T. Enzymatic Synthesis and Structural Confirmation of Novel Oligosaccharide, D-Fructofuranose-linked Chitin Oligosaccharide. J Appl Glycosci (1999). 2020 Nov 20;67(4):129-135. doi: 10.5458/jag.jag.JAG-2020_0009. eCollection 2020. PMID: 34354539; PMCID: PMC8116863.
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PCN Art Brut Series No. 18, Artwork Description.

Psychiatry and clinical neurosciences

Hosaka K.
PMID: 33269502
Psychiatry Clin Neurosci. 2020 Dec;74(12):674. doi: 10.1111/pcn.13164.

No abstract available.

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Hosaka K. PCN Art Brut Series No. 18, Artwork Description. Psychiatry Clin Neurosci. 2020;74(12):674doi: 10.1111/pcn.13164.
Hosaka, K. (2020). PCN Art Brut Series No. 18, Artwork Description. Psychiatry and clinical neurosciences, 74(12), 674. https://doi.org/10.1111/pcn.13164
Hosaka, Kenjiro. "PCN Art Brut Series No. 18, Artwork Description." Psychiatry and clinical neurosciences vol. 74,12 (2020): 674. doi: https://doi.org/10.1111/pcn.13164
Hosaka K. PCN Art Brut Series No. 18, Artwork Description. Psychiatry Clin Neurosci. 2020 Dec;74(12):674. doi: 10.1111/pcn.13164. PMID: 33269502.
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Identification of pulvomycin as an inhibitor of the futalosine pathway.

The Journal of antibiotics

Ogasawara Y, Umetsu S, Inahashi Y, Nonaka K, Dairi T.
PMID: 34417567
J Antibiot (Tokyo). 2021 Nov;74(11):825-829. doi: 10.1038/s41429-021-00465-8. Epub 2021 Aug 20.

Menaquinone is an essential cofactor in the electron-transfer pathway for bacteria. Menaquinone is biosynthesized from chorismate using either the well-known canonical pathway established by pioneering studies in model microorganisms or the futalosine pathway, which we discovered in Streptomyces. Because...

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Ogasawara Y, Umetsu S, Inahashi Y, et al. Identification of pulvomycin as an inhibitor of the futalosine pathway. J Antibiot (Tokyo). 2021;74(11):825-829doi: 10.1038/s41429-021-00465-8.
Ogasawara, Y., Umetsu, S., Inahashi, Y., Nonaka, K., & Dairi, T. (2021). Identification of pulvomycin as an inhibitor of the futalosine pathway. The Journal of antibiotics, 74(11), 825-829. https://doi.org/10.1038/s41429-021-00465-8
Ogasawara, Yasushi, et al. "Identification of pulvomycin as an inhibitor of the futalosine pathway." The Journal of antibiotics vol. 74,11 (2021): 825-829. doi: https://doi.org/10.1038/s41429-021-00465-8
Ogasawara Y, Umetsu S, Inahashi Y, Nonaka K, Dairi T. Identification of pulvomycin as an inhibitor of the futalosine pathway. J Antibiot (Tokyo). 2021 Nov;74(11):825-829. doi: 10.1038/s41429-021-00465-8. Epub 2021 Aug 20. PMID: 34417567.
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Adropin decreases endothelial monolayer permeability after cell-free hemoglobin exposure and reduces MCP-1-induced macrophage transmigration.

Biochemical and biophysical research communications

Dodd WS, Patel D, Lucke-Wold B, Hosaka K, Chalouhi N, Hoh BL.
PMID: 34710824
Biochem Biophys Res Commun. 2021 Dec 10;582:105-110. doi: 10.1016/j.bbrc.2021.10.032. Epub 2021 Oct 16.

BACKGROUND: Cell-free heme-containing proteins mediate endothelial injury in a variety of disease states including subarachnoid hemorrhage and sepsis by increasing endothelial permeability. Inflammatory cells are also attracted to sites of vascular injury by monocyte chemotactic protein 1 (MCP-1) and...

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Dodd WS, Patel D, Lucke-Wold B, et al. Adropin decreases endothelial monolayer permeability after cell-free hemoglobin exposure and reduces MCP-1-induced macrophage transmigration. Biochem Biophys Res Commun. 2021;582:105-110doi: 10.1016/j.bbrc.2021.10.032.
Dodd, W. S., Patel, D., Lucke-Wold, B., Hosaka, K., Chalouhi, N., & Hoh, B. L. (2021). Adropin decreases endothelial monolayer permeability after cell-free hemoglobin exposure and reduces MCP-1-induced macrophage transmigration. Biochemical and biophysical research communications, 582105-110. https://doi.org/10.1016/j.bbrc.2021.10.032
Dodd, William S, et al. "Adropin decreases endothelial monolayer permeability after cell-free hemoglobin exposure and reduces MCP-1-induced macrophage transmigration." Biochemical and biophysical research communications vol. 582 (2021): 105-110. doi: https://doi.org/10.1016/j.bbrc.2021.10.032
Dodd WS, Patel D, Lucke-Wold B, Hosaka K, Chalouhi N, Hoh BL. Adropin decreases endothelial monolayer permeability after cell-free hemoglobin exposure and reduces MCP-1-induced macrophage transmigration. Biochem Biophys Res Commun. 2021 Dec 10;582:105-110. doi: 10.1016/j.bbrc.2021.10.032. Epub 2021 Oct 16. PMID: 34710824.
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A case of fetal-onset type 3 familial hemophagocytic lymphohistiocytosis surviving without severe complications after early diagnosis and treatment.

Pediatric blood & cancer

Matsumoto T, Fukushima H, Fujiyama S, Nagatomo K, Hosaka S, Suzuki R, Yamaki Y, Kanai Y, Shibata H, Yasumi T, Isshiki K, Kato M, Miyazono Y, Takada H.
PMID: 33769695
Pediatr Blood Cancer. 2021 Jul;68(7):e29016. doi: 10.1002/pbc.29016. Epub 2021 Mar 26.

No abstract available.

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Matsumoto T, Fukushima H, Fujiyama S, et al. A case of fetal-onset type 3 familial hemophagocytic lymphohistiocytosis surviving without severe complications after early diagnosis and treatment. Pediatr Blood Cancer. 2021;68(7):e29016doi: 10.1002/pbc.29016.
Matsumoto, T., Fukushima, H., Fujiyama, S., Nagatomo, K., Hosaka, S., Suzuki, R., Yamaki, Y., Kanai, Y., Shibata, H., Yasumi, T., Isshiki, K., Kato, M., Miyazono, Y., & Takada, H. (2021). A case of fetal-onset type 3 familial hemophagocytic lymphohistiocytosis surviving without severe complications after early diagnosis and treatment. Pediatric blood & cancer, 68(7), e29016. https://doi.org/10.1002/pbc.29016
Matsumoto, Takashi, et al. "A case of fetal-onset type 3 familial hemophagocytic lymphohistiocytosis surviving without severe complications after early diagnosis and treatment." Pediatric blood & cancer vol. 68,7 (2021): e29016. doi: https://doi.org/10.1002/pbc.29016
Matsumoto T, Fukushima H, Fujiyama S, Nagatomo K, Hosaka S, Suzuki R, Yamaki Y, Kanai Y, Shibata H, Yasumi T, Isshiki K, Kato M, Miyazono Y, Takada H. A case of fetal-onset type 3 familial hemophagocytic lymphohistiocytosis surviving without severe complications after early diagnosis and treatment. Pediatr Blood Cancer. 2021 Jul;68(7):e29016. doi: 10.1002/pbc.29016. Epub 2021 Mar 26. PMID: 33769695.
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Sedation and Ventilator Liberation Protocol vs Usual Care and Duration of Invasive Ventilation in Pediatric Intensive Care Units.

JAMA

Nosaka N, Masuda T.
PMID: 34905039
JAMA. 2021 Dec 14;326(22):2328-2329. doi: 10.1001/jama.2021.17728.

No abstract available.

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Nosaka N, Masuda T. Sedation and Ventilator Liberation Protocol vs Usual Care and Duration of Invasive Ventilation in Pediatric Intensive Care Units. JAMA. 2021;326(22):2328-2329doi: 10.1001/jama.2021.17728.
Nosaka, N., & Masuda, T. (2021). Sedation and Ventilator Liberation Protocol vs Usual Care and Duration of Invasive Ventilation in Pediatric Intensive Care Units. JAMA, 326(22), 2328-2329. https://doi.org/10.1001/jama.2021.17728
Nosaka, Nobuyuki, and Masuda, Takahiro. "Sedation and Ventilator Liberation Protocol vs Usual Care and Duration of Invasive Ventilation in Pediatric Intensive Care Units." JAMA vol. 326,22 (2021): 2328-2329. doi: https://doi.org/10.1001/jama.2021.17728
Nosaka N, Masuda T. Sedation and Ventilator Liberation Protocol vs Usual Care and Duration of Invasive Ventilation in Pediatric Intensive Care Units. JAMA. 2021 Dec 14;326(22):2328-2329. doi: 10.1001/jama.2021.17728. PMID: 34905039.
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