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Preclinical studies of efficacy thresholds and tolerability of a clinically ready lentiviral vector for pyruvate kinase deficiency treatment.

Molecular therapy. Methods & clinical development

Navarro S, Quintana-Bustamante O, Sanchez-Dominguez R, Lopez-Manzaneda S, Ojeda-Perez I, Garcia-Torralba A, Alberquilla O, Law K, Beard BC, Bastone A, Rothe M, Villanueva M, Ramirez JC, Fañanas-Baquero S, Nieto-Romero V, Molinos-Vicente A, Gutierrez S, Nicoletti E, García-Bravo M, Bueren JA, Schwartz JD, Segovia JC.
PMID: 34514027
Mol Ther Methods Clin Dev. 2021 Jul 29;22:350-359. doi: 10.1016/j.omtm.2021.07.006. eCollection 2021 Sep 10.

Pyruvate kinase deficiency (PKD) is a rare autosomal recessive disorder caused by mutations in the

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Navarro S, Quintana-Bustamante O, Sanchez-Dominguez R, et al. Preclinical studies of efficacy thresholds and tolerability of a clinically ready lentiviral vector for pyruvate kinase deficiency treatment. Mol Ther Methods Clin Dev. 2021;22:350-359doi: 10.1016/j.omtm.2021.07.006.
Navarro, S., Quintana-Bustamante, O., Sanchez-Dominguez, R., Lopez-Manzaneda, S., Ojeda-Perez, I., Garcia-Torralba, A., Alberquilla, O., Law, K., Beard, B. C., Bastone, A., Rothe, M., Villanueva, M., Ramirez, J. C., Fañanas-Baquero, S., Nieto-Romero, V., Molinos-Vicente, A., Gutierrez, S., Nicoletti, E., García-Bravo, M., Bueren, J. A., Schwartz, J. D., & Segovia, J. C. (2021). Preclinical studies of efficacy thresholds and tolerability of a clinically ready lentiviral vector for pyruvate kinase deficiency treatment. Molecular therapy. Methods & clinical development, 22350-359. https://doi.org/10.1016/j.omtm.2021.07.006
Navarro, Susana, et al. "Preclinical studies of efficacy thresholds and tolerability of a clinically ready lentiviral vector for pyruvate kinase deficiency treatment." Molecular therapy. Methods & clinical development vol. 22 (2021): 350-359. doi: https://doi.org/10.1016/j.omtm.2021.07.006
Navarro S, Quintana-Bustamante O, Sanchez-Dominguez R, Lopez-Manzaneda S, Ojeda-Perez I, Garcia-Torralba A, Alberquilla O, Law K, Beard BC, Bastone A, Rothe M, Villanueva M, Ramirez JC, Fañanas-Baquero S, Nieto-Romero V, Molinos-Vicente A, Gutierrez S, Nicoletti E, García-Bravo M, Bueren JA, Schwartz JD, Segovia JC. Preclinical studies of efficacy thresholds and tolerability of a clinically ready lentiviral vector for pyruvate kinase deficiency treatment. Mol Ther Methods Clin Dev. 2021 Jul 29;22:350-359. doi: 10.1016/j.omtm.2021.07.006. eCollection 2021 Sep 10. PMID: 34514027; PMCID: PMC8408550.
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Psychometric Evaluation of a 10-Item Health Insurance Knowledge Scale.

Journal of nursing measurement

James TG, David Miller M, Nicolette G, Cheong J.
PMID: 34518425
J Nurs Meas. 2021 Dec 01;29(3):491-504. doi: 10.1891/JNM-D-20-00019. Epub 2021 Sep 13.

BACKGROUND: College students are a priority population for health insurance literacy interventions. Yet, there are few psychometric studies on measuring health insurance knowledge - a core construct of health insurance literacy.METHODS: We administered a health insurance survey to 2,250...

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James TG, David Miller M, Nicolette G, et al. Psychometric Evaluation of a 10-Item Health Insurance Knowledge Scale. J Nurs Meas. 2021;29(3):491-504doi: 10.1891/JNM-D-20-00019.
James, T. G., David Miller, M., Nicolette, G., & Cheong, J. (2021). Psychometric Evaluation of a 10-Item Health Insurance Knowledge Scale. Journal of nursing measurement, 29(3), 491-504. https://doi.org/10.1891/JNM-D-20-00019
James, Tyler G, et al. "Psychometric Evaluation of a 10-Item Health Insurance Knowledge Scale." Journal of nursing measurement vol. 29,3 (2021): 491-504. doi: https://doi.org/10.1891/JNM-D-20-00019
James TG, David Miller M, Nicolette G, Cheong J. Psychometric Evaluation of a 10-Item Health Insurance Knowledge Scale. J Nurs Meas. 2021 Dec 01;29(3):491-504. doi: 10.1891/JNM-D-20-00019. Epub 2021 Sep 13. PMID: 34518425.
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CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI - difference from BNP visualized by targeted cGMP biosensors.

Cardiovascular research

Manfra O, Calamera G, Froese A, Arunthavarajah D, Surdo NC, Meier S, Melleby AO, Aasrum M, Aronsen JM, Nikolaev VO, Zaccolo M, Moltzau LR, Levy FO, Andressen KW.
PMID: 33970224
Cardiovasc Res. 2021 May 10; doi: 10.1093/cvr/cvab167. Epub 2021 May 10.

AIMS: Guanylyl cyclase-B (GC-B; natriuretic peptide receptor-B, NPR-B) stimulation by C-type natriuretic peptide (CNP) increases cGMP and causes a lusitropic and negative inotropic response in adult myocardium. These effects are not mimicked by NPR-A (GC-A) stimulation by brain natriuretic...

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Manfra O, Calamera G, Froese A, et al. CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI - difference from BNP visualized by targeted cGMP biosensors. Cardiovasc Res. 2021;doi: 10.1093/cvr/cvab167.
Manfra, O., Calamera, G., Froese, A., Arunthavarajah, D., Surdo, N. C., Meier, S., Melleby, A. O., Aasrum, M., Aronsen, J. M., Nikolaev, V. O., Zaccolo, M., Moltzau, L. R., Levy, F. O., & Andressen, K. W. (2021). CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI - difference from BNP visualized by targeted cGMP biosensors. Cardiovascular research, . https://doi.org/10.1093/cvr/cvab167
Manfra, Ornella, et al. "CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI - difference from BNP visualized by targeted cGMP biosensors." Cardiovascular research vol. (2021). doi: https://doi.org/10.1093/cvr/cvab167
Manfra O, Calamera G, Froese A, Arunthavarajah D, Surdo NC, Meier S, Melleby AO, Aasrum M, Aronsen JM, Nikolaev VO, Zaccolo M, Moltzau LR, Levy FO, Andressen KW. CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI - difference from BNP visualized by targeted cGMP biosensors. Cardiovasc Res. 2021 May 10; doi: 10.1093/cvr/cvab167. Epub 2021 May 10. PMID: 33970224.
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Showing 625 to 627 of 627 entries