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Showing 1069 to 1077 of 1077 entries
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Pediatric HIV-1 Acquisition and Lifelong Consequences of Infant Infection.

Current immunology reviews

Nelson CS, Fouda GGA, Permar SR.
PMID: 33223981
Curr Immunol Rev. 2019;15(1):131-138. doi: 10.2174/1573395514666180531074047.

Increased availability of antiretroviral therapy to pregnant and breastfeeding women in resource-limited areas has proven remarkably successful at reducing HIV vertical transmission rates over the past several decades. Yet, still more than 170,000 children are infected annually due to...

Regulation of CEACAM5 and Therapeutic Efficacy of an Anti-CEACAM5-SN38 Antibody-drug Conjugate in Neuroendocrine Prostate Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

DeLucia DC, Cardillo TM, Ang L, Labrecque MP, Zhang A, Hopkins JE, De Sarkar N, Coleman I, da Costa RMG, Corey E, True LD, Haffner MC, Schweizer MT, Morrissey C, Nelson PS, Lee JK.
PMID: 33199493
Clin Cancer Res. 2021 Feb 01;27(3):759-774. doi: 10.1158/1078-0432.CCR-20-3396. Epub 2020 Nov 16.

PURPOSE: Neuroendocrine prostate cancer (NEPC) is an aggressive form of castration-resistant prostate cancer (CRPC) for which effective therapies are lacking. We previously identified carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) as a promising NEPC cell surface antigen. Here we...

Fruit secondary metabolites shape seed dispersal effectiveness.

Trends in ecology & evolution

Nelson AS, Whitehead SR.
PMID: 34509316
Trends Ecol Evol. 2021 Dec;36(12):1113-1123. doi: 10.1016/j.tree.2021.08.005. Epub 2021 Sep 08.

Plant secondary metabolites (PSMs) play a central role in seed dispersal and fruit defense, with potential for large impacts on plant fitness and demography. Yet because PSMs can have multiple interactive functions across seed dispersal stages, we must systematically...

Examining effects of habitual physical activity and body composition on bone structure in early post-menopausal women: a pQCT analysis.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

Flores LE, Nelson S, Waltman N, Kupzyk K, Lappe J, Mack L, Bilek LD.
PMID: 34510230
Osteoporos Int. 2021 Sep 11; doi: 10.1007/s00198-021-06146-4. Epub 2021 Sep 11.

After menopause, bones decline in structure and can break more easily. Physical activity can strengthen bones. This study investigated how activity and body composition can impact bone structure in post-menopausal women. Higher levels of physical activity were positively associated...

Rapid establishment of a frontline field laboratory in response to an imported outbreak of Ebola virus disease in western Uganda, June 2019.

PLoS neglected tropical diseases

Schuh AJ, Kyondo J, Graziano J, Balinandi S, Kainulainen MH, Tumusiime A, Nyakarahuka L, Mulei S, Baluku J, Lonergan W, Mayer O, Masereka R, Masereka F, Businge E, Gatare A, Kabyanga L, Muhindo S, Mugabe R, Makumbi I, Kayiwa J, Wetaka MM, Brown V, Ojwang J, Nelson L, Millard M, Nichol ST, Montgomery JM, Taboy CH, Lutwama JJ, Klena JD.
PMID: 34860831
PLoS Negl Trop Dis. 2021 Dec 03;15(12):e0009967. doi: 10.1371/journal.pntd.0009967. eCollection 2021 Dec.

The Democratic Republic of the Congo (DRC) declared an Ebola virus disease (EVD) outbreak in North Kivu in August 2018. By June 2019, the outbreak had spread to 26 health zones in northeastern DRC, causing >2,000 reported cases and...

Modern Lung Magnetic Resonance Imaging to Screen for Pulmonary Complications in Patients with Dyskeratosis Congenita.

American journal of respiratory and critical care medicine

Walkup LL, Myers KC, Willmering MM, Mehta PA, Nelson AS, Fleck RJ, Woods JC, Davies SM, Towe CT.
PMID: 34516939
Am J Respir Crit Care Med. 2021 Dec 01;204(11):1340-1343. doi: 10.1164/rccm.202103-0736LE.

No abstract available.

Aggressive osteoblastoma with a secondary aneurysmal bone cyst treated with denosumab.

Rare tumors

Wong K, Chantharasamee J, Nelson S, Eckardt MA, Motamedi K, Hornicek FJ, Singh AS.
PMID: 34484648
Rare Tumors. 2021 Aug 29;13:20363613211034710. doi: 10.1177/20363613211034710. eCollection 2021.

Osteoblastomas and aneurysmal bone cysts (ABC) are rare benign bone tumors that make up about 1%-2% of primary bone malignancies, typically occurring in young patients with a median age of 20 years, most commonly effecting the axial skeleton. ABCs...

Ruxolitinib for the treatment of chronic GVHD and overlap syndrome in children and young adults.

Transplantation

Wang YM, Teusink-Cross A, Elborai Y, Krupski MC, Nelson AS, Grimley MS, Flannery A, Mehta PA, Bleesing JJ, Chandra S, Kumar AR, Myers KC, Davies SM, Khandelwal P.
PMID: 33795598
Transplantation. 2021 Mar 26; doi: 10.1097/TP.0000000000003768. Epub 2021 Mar 26.

BACKGROUND: Ruxolitinib, a JAK1/2 inhibitor, is used to treat chronic graft-versus-host-disease (cGVHD) in adult allogeneic hematopoietic stem cell transplant patients, but experience in children is limited, perhaps due to lack of pediatric dosing information. In this report we describe...

Strategies That Promote Equity in COVID-19 Vaccine Uptake for Black Communities: a Review.

Journal of urban health : bulletin of the New York Academy of Medicine

Dada D, Djiometio JN, McFadden SM, Demeke J, Vlahov D, Wilton L, Wang M, Nelson LE.
PMID: 35018612
J Urban Health. 2022 Jan 11; doi: 10.1007/s11524-021-00594-3. Epub 2022 Jan 11.

Black communities have had a high burden of COVID-19 cases, hospitalizations, and death, yet rates of COVID-19 vaccine uptake among Blacks lag behind other demographic groups. This has been due in part to vaccine hesitancy and multi-level issues around...

Showing 1069 to 1077 of 1077 entries