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Showing 97 to 103 of 103 entries
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Putative mechanism for cancer suppression by PLGA nanoparticles loaded with .

Journal of microencapsulation

Shabestarian H, Homayouni Tabrizi M, Movahedi M, Neamati A, Sharifnia F.
PMID: 33951988
J Microencapsul. 2021 Aug;38(5):324-337. doi: 10.1080/02652048.2021.1917715. Epub 2021 May 05.

Synthesis and investigation of biological activity of

Discovery and Lead Optimization of Benzene-1,4-disulfonamides as Oxidative Phosphorylation Inhibitors.

Journal of medicinal chemistry

Xue D, Xu Y, Kyani A, Roy J, Dai L, Sun D, Neamati N.
PMID: 34982568
J Med Chem. 2022 Jan 04; doi: 10.1021/acs.jmedchem.1c01509. Epub 2022 Jan 04.

Inhibition of oxidative phosphorylation (OXPHOS) is a promising therapeutic strategy for select cancers that are dependent on aerobic metabolism. Here, we report the discovery, optimization, and structure-activity relationship (SAR) study of a series of novel OXPHOS inhibitors. The hit...

Research in pharmaceutical sciences

Shirzad S, Neamati A, Vafaee F, Ghazavi H.
PMID: 33828600
Res Pharm Sci. 2020 Nov 27;15(6):571-582. doi: 10.4103/1735-5362.301342. eCollection 2020 Dec.

BACKGROUND AND PURPOSE: Venenum Bufonis is a Chinese traditional medicine produced from the glandular secretions of toads that contain biogenic amines, which have anti-inflammatory properties. The present study aimed to examine the effect of EXPERIMENTAL APPROACH: Thirty-eight male Wistar...

Ensembl Genomes 2022: an expanding genome resource for non-vertebrates.

Nucleic acids research

Yates AD, Allen J, Amode RM, Azov AG, Barba M, Becerra A, Bhai J, Campbell LI, Carbajo Martinez M, Chakiachvili M, Chougule K, Christensen M, Contreras-Moreira B, Cuzick A, Da Rin Fioretto L, Davis P, De Silva NH, Diamantakis S, Dyer S, Elser J, Filippi CV, Gall A, Grigoriadis D, Guijarro-Clarke C, Gupta P, Hammond-Kosack KE, Howe KL, Jaiswal P, Kaikala V, Kumar V, Kumari S, Langridge N, Le T, Luypaert M, Maslen GL, Maurel T, Moore B, Muffato M, Mushtaq A, Naamati G, Naithani S, Olson A, Parker A, Paulini M, Pedro H, Perry E, Preece J, Quinton-Tulloch M, Rodgers F, Rosello M, Ruffier M, Seager J, Sitnik V, Szpak M, Tate J, Tello-Ruiz MK, Trevanion SJ, Urban M, Ware D, Wei S, Williams G, Winterbottom A, Zarowiecki M, Finn RD, Flicek P.
PMID: 34791415
Nucleic Acids Res. 2021 Nov 13; doi: 10.1093/nar/gkab1007. Epub 2021 Nov 13.

Ensembl Genomes (https://www.ensemblgenomes.org) provides access to non-vertebrate genomes and analysis complementing vertebrate resources developed by the Ensembl project (https://www.ensembl.org). The two resources collectively present genome annotation through a consistent set of interfaces spanning the tree of life presenting genome...

Prognostic impact of spread through air spaces in lung adenocarcinoma.

Interactive cardiovascular and thoracic surgery

Mantovani S, Pernazza A, Bassi M, Amore D, Vannucci J, Poggi C, Diso D, d'Amati G, Della Rocca C, Rendina EA, Venuta F, Anile M.
PMID: 34662397
Interact Cardiovasc Thorac Surg. 2021 Oct 18; doi: 10.1093/icvts/ivab289. Epub 2021 Oct 18.

OBJECTIVE: Spread through air spaces (STAS) is a pattern of invasion present in some adenocarcinomas (ADC). The goal of this study was to assess the impact of STAS in patients treated with different types of surgical resections and on...

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Clinical and experimental immunology

Riff R, Naamani O, Mazar J, Haviv YS, Chaimovitz C, Douvdevani A.
PMID: 33894002
Clin Exp Immunol. 2021 Sep;205(3):278-287. doi: 10.1111/cei.13607. Epub 2021 Jun 02.

Adenosine is a potent modulator that has a tremendous effect on the immune system. Adenosine affects T cell activity, and is necessary in maintaining the T helper/regulatory T cell (T

Verbascoside inhibits paraquate-induced pulmonary toxicity via modulating oxidative stress, inflammation, apoptosis and DNA damage in A549 cell.

Drug and chemical toxicology

Khorashadizadeh N, Neamati A, Moshiri M, Etemad L.
PMID: 34607471
Drug Chem Toxicol. 2021 Oct 04;1-9. doi: 10.1080/01480545.2021.1917467. Epub 2021 Oct 04.

Paraquat (PQ), one of the most frequently used herbicides, can cause serious health problems in an exposed individual. In the present study, we investigated the protective effect of verbascoside (VB), a phenylpropanoid glycoside from lemon verbena, against PQ-induced A549...

Showing 97 to 103 of 103 entries