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Showing 1273 to 1281 of 1281 entries
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Evaluation of diazepam as a drug treatment for water hemlock (Cicuta species) poisoning in Spanish goats.

Toxicon : official journal of the International Society on Toxinology

Green BT, Stonecipher CA, Welch KD, Lee ST, Cook D.
PMID: 34871669
Toxicon. 2022 Jan 15;205:79-83. doi: 10.1016/j.toxicon.2021.12.003. Epub 2021 Dec 03.

Water hemlocks (Cicuta spp.) are toxic members of the Apiaceae plant family. The best drug treatment for the convulsions associated with acute water hemlock poisoning in livestock and humans has not been determined experimentally. This work compared the therapeutic...

Premedication with pregabalin 150mg versus 300mg for postoperative pain relief after laparoscopic cholecystectomy.

Journal of anaesthesiology, clinical pharmacology

Singh T, Kathuria S, Jain R, Sood D, Gupta S.
PMID: 33840934
J Anaesthesiol Clin Pharmacol. 2020 Oct-Dec;36(4):518-523. doi: 10.4103/joacp.JOACP_440_19. Epub 2021 Jan 18.

BACKGROUND AND AIMS: Pregabalin has been used in various studies for postoperative pain relief in varying doses. However, there is no conclusive evidence to support a safe and effective dose of pregabalin. The present study was designed to compare...

A comparative study of desflurane versus sevoflurane in obese patients: Effect on recovery profile.

Journal of anaesthesiology, clinical pharmacology

Bansal T, Garg K, Katyal S, Sood D, Grewal A, Kumar A.
PMID: 33840938
J Anaesthesiol Clin Pharmacol. 2020 Oct-Dec;36(4):541-545. doi: 10.4103/joacp.JOACP_307_19. Epub 2021 Jan 18.

BACKGROUND AND AIMS: Anesthesia in obese patients is difficult due to associated comorbidities and altered physiology. Desflurane and sevoflurane have a low fat-blood solubility coefficient and are better suited in these patients to achieve a rapid emergence. We studied...

Monitoring populations at increased risk for SARS-CoV-2 infection in the community using population-level demographic and behavioural surveillance.

The Lancet regional health. Europe

Pritchard E, Jones J, Vihta KD, Stoesser N, Matthews PPC, Eyre DW, House T, Bell JI, Newton PJN, Farrar J, Crook PD, Hopkins S, Cook D, Rourke E, Studley R, Diamond PI, Peto PT, Pouwels KB, Walker PAS.
PMID: 34927119
Lancet Reg Health Eur. 2022 Feb;13:100282. doi: 10.1016/j.lanepe.2021.100282. Epub 2021 Dec 12.

BACKGROUND: The COVID-19 pandemic is rapidly evolving, with emerging variants and fluctuating control policies. Real-time population screening and identification of groups in whom positivity is highest could help monitor spread and inform public health messaging and strategy.METHODS: To develop...

Cost-effectiveness of a European preventive cardiology programme in primary care: a Markov modelling approach.

BMJ open

Mistry H, Morris S, Dyer M, Kotseva K, Wood D, Buxton M.
PMID: 23065443
BMJ Open. 2012 Oct 11;2(5). doi: 10.1136/bmjopen-2012-001029. Print 2012.

OBJECTIVE: To investigate the longer-term cost-effectiveness of a nurse-coordinated preventive cardiology programme for primary prevention of cardiovascular disease (CVD) compared to routine practice from a health service perspective.DESIGN: A matched, paired cluster-randomised controlled trial.SETTING: Six pairs of general practices...

Tissue Multiplex Analyte Detection in Anatomic Pathology - Pathways to Clinical Implementation.

Frontiers in molecular biosciences

Wharton KA, Wood D, Manesse M, Maclean KH, Leiss F, Zuraw A.
PMID: 34386519
Front Mol Biosci. 2021 Jul 27;8:672531. doi: 10.3389/fmolb.2021.672531. eCollection 2021.

No abstract available.

Preliminary Evaluation of a Recombinant Rift Valley Fever Virus Glycoprotein Subunit Vaccine Providing Full Protection against Heterologous Virulent Challenge in Cattle.

Vaccines

Wilson WC, Faburay B, Trujillo JD, Ragan I, Sunwoo SY, Morozov I, Shivanna V, Balogh A, Urbaniak K, McVey DS, Bold D, Gaudreault NN, Schirtzinger EE, Ma W, Richt JA.
PMID: 34358166
Vaccines (Basel). 2021 Jul 06;9(7). doi: 10.3390/vaccines9070748.

Rift Valley fever virus (RVFV) is a mosquito-borne zoonotic pathogen that causes periodic outbreaks of abortion in ruminant species and hemorrhagic disease in humans in sub-Saharan Africa. These outbreaks have a significant impact on veterinary and public health. Its...

Nanotransfection-based vasculogenic cell reprogramming drives functional recovery in a mouse model of ischemic stroke.

Science advances

Lemmerman LR, Balch MHH, Moore JT, Alzate-Correa D, Rincon-Benavides MA, Salazar-Puerta A, Gnyawali S, Harris HN, Lawrence W, Ortega-Pineda L, Wilch L, Risser IB, Maxwell AJ, Duarte-Sanmiguel S, Dodd D, Guio-Vega GP, McTigue DM, Arnold WD, Nimjee SM, Sen CK, Khanna S, Rink C, Higuita-Castro N, Gallego-Perez D.
PMID: 33741587
Sci Adv. 2021 Mar 19;7(12). doi: 10.1126/sciadv.abd4735. Print 2021 Mar.

Ischemic stroke causes vascular and neuronal tissue deficiencies that could lead to substantial functional impairment and/or death. Although progenitor-based vasculogenic cell therapies have shown promise as a potential rescue strategy following ischemic stroke, current approaches face major hurdles. Here,...

A first-in-human study of BLZ-100 (tozuleristide) demonstrates tolerability and safety in skin cancer patients.

Contemporary clinical trials communications

Yamada M, Miller DM, Lowe M, Rowe C, Wood D, Soyer HP, Byrnes-Blake K, Parrish-Novak J, Ishak L, Olson JM, Brandt G, Griffin P, Spelman L, Prow TW.
PMID: 34401600
Contemp Clin Trials Commun. 2021 Aug 04;23:100830. doi: 10.1016/j.conctc.2021.100830. eCollection 2021 Sep.

BLZ-100 (tozuleristide) is an intraoperative fluorescent imaging agent that selectively detects malignant tissue and can be used in real time to guide tumor resection. The purpose of this study was to assess the safety, tolerability, and pharmacokinetics of BLZ-100...

Showing 1273 to 1281 of 1281 entries