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Showing 13 to 24 of 116 entries
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Effect of the DASH Diet on Pre- and Stage 1 Hypertensive Individuals in a Free-Living Environment.

Nutrition and metabolic insights

Malloy-McFall J, Barkley JE, Gordon KL, Burzminski N, Glickman EL.
PMID: 23966788
Nutr Metab Insights. 2010 Mar 31;3:15-23. doi: 10.4137/NMI.S3871. eCollection 2010.

BACKGROUND: Dietary Approaches to Stop Hypertension (DASH) has been shown to successfully reduce systolic (SBP) and diastolic blood pressure (DBP) when evaluated in clinically controlled environments but there is a lack of information regarding the efficacy of the original...

Strategies for rapid risk assessment of color additives used in medical devices.

Toxicological sciences : an official journal of the Society of Toxicology

Saylor DM, Chandrasekar V, Simon DD, Turner P, Markley LC, Hood AM.
PMID: 31388681
Toxicol Sci. 2019 Aug 06; doi: 10.1093/toxsci/kfz179. Epub 2019 Aug 06.

Many polymeric medical devices contain color additives for differentiation or labeling. While some additives can be toxic under certain conditions, the risk associated with the use of these additives in medical device applications is not well established, and evaluating...

Using antibody directed phototherapy to target oesophageal adenocarcinoma with heterogeneous HER2 expression.

Oncotarget

Pye H, Butt MA, Funnell L, Reinert HW, Puccio I, Rehman Khan SU, Saouros S, Marklew JS, Stamati I, Qurashi M, Haidry R, Sehgal V, Oukrif D, Gandy M, Whitaker HC, Rodriguez-Justo M, Novelli M, Hamoudi R, Yahioglu G, Deonarain MP, Lovat LB.
PMID: 29796164
Oncotarget. 2018 May 01;9(33):22945-22959. doi: 10.18632/oncotarget.25159. eCollection 2018 May 01.

Early oesophageal adenocarcinoma (OA) and pre-neoplastic dysplasia may be treated with endoscopic resection and ablative techniques such as photodynamic therapy (PDT). Though effective, discrete areas of disease may be missed leading to recurrence. PDT further suffers from the side...

Pediatric Antimicrobial Stewardship: State of the Art.

Current infectious disease reports

Godbout EJ, Pakyz AL, Markley JD, Noda AJ, Stevens MP.
PMID: 30069834
Curr Infect Dis Rep. 2018 Aug 01;20(10):39. doi: 10.1007/s11908-018-0644-7.

PURPOSE OF REVIEW: We aim to systematically review the literature on the effectiveness of pediatric antimicrobial stewardship programs (ASPs) and antimicrobial stewardship (AS) strategies in the United States (US) inpatient setting. Furthermore, we review current gaps and challenges for...

Cell phone use predicts being an "active couch potato": results from a cross-sectional survey of sufficiently active college students.

Digital health

Lepp A, Barkley JE.
PMID: 31019724
Digit Health. 2019 Apr 12;5:2055207619844870. doi: 10.1177/2055207619844870. eCollection 2019.

OBJECTIVE: "Active couch potato" describes an individual who is sufficiently physically active yet highly sedentary. Cell phones promote activities understood as sedentary behaviors (e.g. watching videos). Research demonstrates that cell phone use is positively associated with sedentary behavior. Although...

Automated evaluation of consistency within the PubChem Compound database.

Scientific data

Dashti H, Wedell JR, Westler WM, Markley JL, Eghbalnia HR.
PMID: 30778259
Sci Data. 2019 Feb 19;6:190023. doi: 10.1038/sdata.2019.23.

Identification of discrepant data in aggregated databases is a key step in data curation and remediation. We have applied the ALATIS approach, which is based on the international chemical shift identifier (InChI) model, to the full PubChem Compound database...

The BRPF1 bromodomain is a molecular reader of di-acetyllysine.

Current research in structural biology

Obi JO, Lubula MY, Cornilescu G, Henrickson A, McGuire K, Evans CM, Phillips M, Boyson SP, Demeler B, Markley JL, Glass KC.
PMID: 33554132
Curr Res Struct Biol. 2020;2:104-115. doi: 10.1016/j.crstbi.2020.05.001. Epub 2020 May 12.

Bromodomain-containing proteins are often part of chromatin-modifying complexes, and their activity can lead to altered expression of genes that drive cancer, inflammation and neurological disorders in humans. Bromodomain-PHD finger protein 1 (BRPF1) is part of the MOZ (monocytic leukemic...

Evaluation of Variability in Gait Styles Used by Dogs Completing Weave Poles in Agility Competition and Its Effect on Completion of the Obstacle.

Frontiers in veterinary science

Eicher LD, Markley AP, Shoben A, Sundby AE, Kieves NR.
PMID: 34869735
Front Vet Sci. 2021 Nov 17;8:761493. doi: 10.3389/fvets.2021.761493. eCollection 2021.

No abstract available.

Omega-3 fatty acid supplementation in severe brain trauma: case for a large multicenter trial.

Journal of neurosurgery

Bailes JE, Abusuwwa R, Arshad M, Chowdhry SA, Schleicher D, Hempeck N, Gandhi YN, Jaffa Z, Bokhari F, Karahalios D, Barkley J, Patel V, Sears B.
PMID: 32413868
J Neurosurg. 2020 May 15;1-5. doi: 10.3171/2020.3.JNS20183. Epub 2020 May 15.

No abstract available.

The cytotoxicity of gallium maltolate in glioblastoma cells is enhanced by metformin through combined action on mitochondrial complex 1.

Oncotarget

Alhajala HS, Markley JL, Kim JH, Al-Gizawiy MM, Schmainda KM, Kuo JS, Chitambar CR.
PMID: 32391122
Oncotarget. 2020 Apr 28;11(17):1531-1544. doi: 10.18632/oncotarget.27567. eCollection 2020 Apr 28.

New drugs are needed for glioblastoma, an aggressive brain tumor with a dismal prognosis. We recently reported that gallium maltolate (GaM) retards the growth of glioblastoma in a rat orthotopic brain tumor model by inhibiting mitochondrial function and iron-dependent...

Transient acoustic vaporization signatures unique to low boiling point phase change contrast agents enable super-resolution ultrasound imaging without spatiotemporal filtering.

AIP advances

DeRuiter RM, Markley EN, Rojas JD, Pinton GF, Dayton PA.
PMID: 33094029
AIP Adv. 2020 Oct 19;10(10):105124. doi: 10.1063/5.0029207. eCollection 2020 Oct.

The unique activation signal of phase-change contrast agents (PCCAs or droplets) can be separated from the tissue signal and localized to generate super-resolution (SR) ultrasound (US) images. Lipid-shelled, perfluorocarbon PCCAs can be stochastically vaporized (activated) by a plane wave...

The Acute Effects of the COVID-19 Pandemic on Physical Activity and Sedentary Behavior in University Students and Employees.

International journal of exercise science

Barkley JE, Lepp A, Glickman E, Farnell G, Beiting J, Wiet R, Dowdell B.
PMID: 33042377
Int J Exerc Sci. 2020 Sep 01;13(5):1326-1339. eCollection 2020.

The COVID-19 pandemic has closed non-essential businesses which may alter individuals' leisure behaviors. Consequently, physical activity and sedentary behavior may be negatively impacted as many fitness and recreational centers have been closed. This study aimed to examine the impact...

Showing 13 to 24 of 116 entries