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Showing 25 to 36 of 276 entries
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Nonconstrictive epicarditis mimicking a cardiac mass in a 71-year-old Caucasian man: a case report and review of the literature.

Journal of medical case reports

Margolis AM, Emmerman AB, Rascon M, Chaudhry SI.
PMID: 19126192
J Med Case Rep. 2009 Jan 06;3:2. doi: 10.1186/1752-1947-3-2.

INTRODUCTION: Isolated cases of epicarditis are rare. Thus far, all have occurred with constrictive physiology as most cases involve both parietal and visceral pericardium. We report the first case of asymptomatic epicarditis that involved only the visceral pericardium presenting...

B-50/GAP-43 in neuronal development and repair.

Restorative neurology and neuroscience

Gispen WH, Boonstra J, De Graan PN, Jennekens FG, Oestreicher AB, Schotman P, Schrama LH, Verhaagen J, Margolis FL.
PMID: 21551562
Restor Neurol Neurosci. 1990 Jan 01;1(3):237-44. doi: 10.3233/RNN-1990-13410.

The protein kinase C substrate B-50 is identical to the growth-associated protein GAP-43. Although as yet no causal relationship has been established between B-50/GAP-43 and neurite outgrowth, evidence accumulates that the function of the protein relates to neuronal plasticity....

Optical recording of neuronal activity with a genetically-encoded calcium indicator in anesthetized and freely moving mice.

Frontiers in neural circuits

Lütcke H, Murayama M, Hahn T, Margolis DJ, Astori S, Zum Alten Borgloh SM, Göbel W, Yang Y, Tang W, Kügler S, Sprengel R, Nagai T, Miyawaki A, Larkum ME, Helmchen F, Hasan MT.
PMID: 20461230
Front Neural Circuits. 2010 Apr 29;4:9. doi: 10.3389/fncir.2010.00009. eCollection 2010.

Fluorescent calcium (Ca(2+)) indicator proteins (FCIPs) are promising tools for functional imaging of cellular activity in living animals. However, they have still not reached their full potential for in vivo imaging of neuronal activity due to limitations in expression...

Trabecular scaffolds created using micro CT guided fused deposition modeling.

Materials science & engineering. C, Materials for biological applications

Tellis BC, Szivek JA, Bliss CL, Margolis DS, Vaidyanathan RK, Calvert P.
PMID: 21461176
Mater Sci Eng C Mater Biol Appl. 2009 Jan 10;28(1):171-178. doi: 10.1016/j.msec.2006.11.010.

Free form fabrication and high resolution imaging techniques enable the creation of biomimetic tissue engineering scaffolds. A 3D CAD model of canine trabecular bone was produced via micro CT and exported to a fused deposition modeler, to produce polybutylene...

It takes more than two for this tango.

Cell host & microbe

Margolis L.
PMID: 23332149
Cell Host Microbe. 2013 Jan 16;13(1):1-3. doi: 10.1016/j.chom.2013.01.002. Epub 2013 Jan 16.

A paper in this issue by Ogawa et al. (2013) shows that HSV-2-infected keratinocytes in human skin explants release a protein that enhances HIV-1 infection of Langerhans cells in vitro. This may explain the in vivo observation that HSV-2...

In Vitro Techniques for Studies of HIV-1 Promoter Activity.

Methods in molecular medicine

Romerio F, Margolis DM.
PMID: 21380669
Methods Mol Med. 1999;17:197-203. doi: 10.1385/0-89603-369-4:197.

A rather unique feature of the human immunodeficiency virus type-1 (HIV-1) is the structural complexity of the regulatory sequences located in the long-terminal repeat (LTR) promoter region and the number of cellular and viral transcription factors known to interact...

HDAC inhibition induces HIV-1 protein and enables immune-based clearance following latency reversal.

JCI insight

Wu G, Swanson M, Talla A, Graham D, Strizki J, Gorman D, Barnard RJ, Blair W, Søgaard OS, Tolstrup M, Østergaard L, Rasmussen TA, Sekaly RP, Archin NM, Margolis DM, Hazuda DJ, Howell BJ.
PMID: 28814661
JCI Insight. 2017 Aug 17;2(16). doi: 10.1172/jci.insight.92901. eCollection 2017 Aug 17.

Promising therapeutic approaches for eradicating HIV include transcriptional activation of provirus from latently infected cells using latency-reversing agents (LRAs) and immune-mediated clearance to purge reservoirs. Accurate detection of cells capable of producing viral antigens and virions, and the measurement...

Interrupting antiretroviral treatment in HIV cure research: scientific and ethical considerations.

Journal of virus eradication

Garner SA, Rennie S, Ananworanich J, Dube K, Margolis DM, Sugarman J, Tressler R, Gilbertson A, Dawson L.
PMID: 28435691
J Virus Erad. 2017 Apr 01;3(2):82-84.

Over the past several years there has been intense activity directed at the possibility of achieving remission or eradication of HIV infection. Current assays for the measurement of latent HIV are insufficient to demonstrate complete clearance of replication-competent HIV....

Ingesting a Combined Carbohydrate and Essential Amino Acid Supplement Compared to a Non-Nutritive Placebo Blunts Mitochondrial Biogenesis-Related Gene Expression after Aerobic Exercise.

Current developments in nutrition

Margolis LM, Murphy NE, Carrigan CT, McClung HL, Pasiakos SM.
PMID: 29955707
Curr Dev Nutr. 2017 May 23;1(6):e000893. doi: 10.3945/cdn.117.000893. eCollection 2017 Jun.

No abstract available.

BI-RADS 3: Current and Future Use of Probably Benign.

Current radiology reports

Lee KA, Talati N, Oudsema R, Steinberger S, Margolies LR.
PMID: 29399419
Curr Radiol Rep. 2018;6(2):5. doi: 10.1007/s40134-018-0266-8. Epub 2018 Jan 27.

PURPOSE OF REVIEW: Probably benign (BI-RADS 3) causes confusion for interpreting physicians and referring physicians and can induce significant patient anxiety. The best uses and evidence for using this assessment category in mammography, breast ultrasound, and breast MRI will...

The role of mitophagy in the regulation of mitochondrial energetic status in neurons.

Autophagy

Han S, Zhang M, Jeong YY, Margolis DJ, Cai Q.
PMID: 33757395
Autophagy. 2021 Dec;17(12):4182-4201. doi: 10.1080/15548627.2021.1907167. Epub 2021 Apr 05.

Mitochondria are the main cellular energy powerhouses and supply most of the energy in the form of ATP to fuel essential neuronal functions through oxidative phosphorylation (OXPHOS). In Alzheimer disease (AD), metabolic and mitochondrial disruptions are an early feature...

Week 96 extension results of a Phase 3 study evaluating long-acting cabotegravir with rilpivirine for HIV-1 treatment.

AIDS (London, England)

Swindells S, Lutz T, Van Zyl L, Porteiro N, Stoll M, Mitha E, Shon A, Benn P, Huang JO, Harrington CM, Hove K, Ford SL, Talarico CL, Chounta V, Crauwels H, Van Solingen-Ristea R, Vanveggel S, Margolis DA, Smith KY, Vandermeulen K, Spreen WR.
PMID: 34261093
AIDS. 2022 Feb 01;36(2):185-194. doi: 10.1097/QAD.0000000000003025.

BACKGROUND: ATLAS (NCT02951052), a phase 3, multicenter, open-label study, demonstrated that switching to injectable cabotegravir (CAB) with rilpivirine (RPV) long-acting dosed every 4 weeks was noninferior at week (W) 48 to continuing three-drug daily oral current antiretroviral therapy (CAR)....

Showing 25 to 36 of 276 entries