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Showing 565 to 576 of 596 entries
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Transcatheter Heart Valve Downstream Fluid Dynamics in an Accelerated Evaluation Environment.

Annals of biomedical engineering

Ponnaluri SV, Deutsch S, Sacks MS, Manning KB.
PMID: 33638029
Ann Biomed Eng. 2021 Sep;49(9):2170-2182. doi: 10.1007/s10439-021-02751-w. Epub 2021 Feb 26.

Transcatheter aortic valve replacements (TAVRs) provide minimally invasive delivery of bioprosthetic heart valves (BHVs) for the treatment of aortic valve disease. While surgical BHVs show efficacy for 8-10 years, long-term TAVR durability remains unknown. Pre-clinical testing evaluates BHV durability...

Role of novel cancer gene SLITRK3 to activate NTRK3 in squamous cell lung cancer.

Molecular biomedicine

Bollig-Fischer A, Bao B, Manning M, Dyson G, Michelhaugh SK, Mittal S, Bepler G, Mamdani H.
PMID: 35006496
Mol Biomed. 2021 Aug 30;2(1):26. doi: 10.1186/s43556-021-00051-2.

The development of targeted therapies that inhibit cancer-driving oncogenes has improved outcomes of patients diagnosed with lung adenocarcinoma (LUAD). In contrast, patients diagnosed with lung squamous cell carcinoma (LUSC) suffer worse survival outcomes and lack effective targeted treatment options....

Reversible Cerebral Vasoconstriction Syndrome Associated With Fluoxetine.

Journal of the Academy of Consultation-Liaison Psychiatry

Manning T, Bartow C, Dunlap M, Kiehl R, Kneale H, Walker A.
PMID: 34371244
J Acad Consult Liaison Psychiatry. 2021 Nov-Dec;62(6):634-644. doi: 10.1016/j.jaclp.2021.07.013. Epub 2021 Aug 08.

BACKGROUND: Reversible cerebral vasoconstriction syndrome (RCVS) is an increasingly recognized neurological syndrome that typically presents with a severe headache. The proposed etiology is transient and segmental constriction of cerebral arteries, which in severe cases can lead to cerebral ischemia....

Maternal morbidity and mortality: an iceberg phenomenon.

BJOG : an international journal of obstetrics and gynaecology

Leitao S, Manning E, Greene RA, Corcoran P.
PMID: 34455672
BJOG. 2022 Feb;129(3):402-411. doi: 10.1111/1471-0528.16880. Epub 2021 Sep 23.

OBJECTIVE: To apply the iceberg model, quantifying absolute and relative incidence, to the four main causes of maternal morbidity and mortality in Ireland: haemorrhage, hypertension, sepsis and thrombosis.DESIGN: Secondary analysis of national data on maternal morbidity and mortality.SETTING: Republic...

Children with medical complexity: A concept analysis.

Nursing forum

Rogers J, Reed MP, Blaine K, Manning H.
PMID: 33625740
Nurs Forum. 2021 Jul;56(3):676-683. doi: 10.1111/nuf.12559. Epub 2021 Feb 24.

AIM: The aim of this paper is to conduct a concept analysis on the term, "children with medical complexity."BACKGROUND: Children with medical complexity (CMC) describes pediatric patients with chronic, sustained acuity; however, there is a lack of consensus in...

Antimalarials for children with Plasmodium vivax infection: Current status, challenges, and research priorities.

Parasitology international

Woon SA, Manning L, Moore BR.
PMID: 34785369
Parasitol Int. 2021 Nov 14;87:102512. doi: 10.1016/j.parint.2021.102512. Epub 2021 Nov 14.

The aim of this narrative review is to summarise efficacy and pharmacokinetic data for Plasmodium vivax in children. The burden of P. vivax malaria in children continues to remain a significant public health issue, and the need for improved...

Burden of increasing opioid use in the treatment of migraine: Results from the Migraine in America Symptoms and Treatment Study.

Headache

Lipton RB, Buse DC, Dodick DW, Schwedt TJ, Singh P, Munjal S, Fanning K, Bostic Bs R, Reed ML.
PMID: 33326608
Headache. 2021 Jan;61(1):103-116. doi: 10.1111/head.14018. Epub 2020 Dec 16.

OBJECTIVE: We sought to assess factors associated with the frequency of self-reported prescription opioid use in persons with migraine, including demographic variables, comorbidities, headache characteristics, and patterns of consultation.BACKGROUND: Despite the dose-dependent effect of opioids on migraine progression and...

The APEC Digital Hub-WONCA Collaborative Framework on Integration of Mental Health into Primary Care in the Asia Pacific.

Journal of multidisciplinary healthcare

Dowrick C, Kassai R, Lam CLK, Lam RW, Manning G, Murphy J, Ng CH, Thuraisingham C.
PMID: 33268991
J Multidiscip Healthc. 2020 Nov 25;13:1693-1704. doi: 10.2147/JMDH.S271070. eCollection 2020.

Mental ill health affects individual well-being and national economic prosperity and makes up a substantial portion of the burden of disease globally, especially in the Asia-Pacific region. Integrating mental health into primary care is widely considered a key strategy...

Pathogenicity of VHL variants in families with non-syndromic von Hippel-Lindau phenotypes: An integrated evaluation of germline and somatic genomic results.

European journal of medical genetics

Rana HQ, Koeller DR, Schwartz A, Manning DK, Schneider KA, Krajewski KM, Choueiri TK, Lindeman NI, Garber JE, Ghazani AA.
PMID: 34628056
Eur J Med Genet. 2021 Dec;64(12):104359. doi: 10.1016/j.ejmg.2021.104359. Epub 2021 Oct 08.

Von Hippel-Lindau (VHL) syndrome is a hereditary tumor syndrome associated with germline loss-of-function pathogenic variants (PVs) in the VHL gene. VHL is classically associated with a high penetrance for many different tumor types. The same tumors may be sporadic...

Prevalence of SARS-CoV-2 infection among people experiencing homelessness in Toronto during the first wave of the COVID-19 pandemic.

Canadian journal of public health = Revue canadienne de sante publique

Luong L, Beder M, Nisenbaum R, Orkin A, Wong J, Damba C, Emond R, Lena S, Wright V, Loutfy M, Bruce-Barrett C, Cheung W, Cheung YK, Williams V, Vanmeurs M, Boozary A, Manning H, Hester J, Hwang SW.
PMID: 34919211
Can J Public Health. 2021 Dec 17; doi: 10.17269/s41997-021-00591-8. Epub 2021 Dec 17.

OBJECTIVES: People experiencing homelessness are at increased risk of SARS-CoV-2 infection. This study reports the point prevalence of SARS-CoV-2 infection during testing conducted at sites serving people experiencing homelessness in Toronto during the first wave of the COVID-19 pandemic....

Long-term follow-up of Phase 2A trial results involving advanced ovarian cancer patients treated with Vigil® in frontline maintenance.

Gynecologic oncology reports

Oh J, Barve M, Senzer N, Aaron P, Manning L, Wallraven G, Bognar E, Stanbery L, Horvath S, Manley M, Nemunaitis J, Walter A, Rocconi RP.
PMID: 33364285
Gynecol Oncol Rep. 2020 Sep 17;34:100648. doi: 10.1016/j.gore.2020.100648. eCollection 2020 Nov.

No abstract available.

3D Microtissues Mimic the Architecture, Estradiol Synthesis and Gap Junction Intercellular Communication of the Avascular Granulosa.

Toxicological sciences : an official journal of the Society of Toxicology

Ip BC, Leary E, Knorlein B, Reich D, Van V, Manning J, Morgan JR.
PMID: 34935973
Toxicol Sci. 2021 Dec 22; doi: 10.1093/toxsci/kfab153. Epub 2021 Dec 22.

Humans are consistently exposed to thousands of untested chemicals that have been detected in the follicular fluid of the ovaries, and can disrupt reproductive health. Human granulosa cells (GCs) are the functional unit of the ovarian follicle with steroidogenic...

Showing 565 to 576 of 596 entries