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Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis.

Medicines (Basel, Switzerland)

Gado F, Digiacomo M, Macchia M, Bertini S, Manera C.
PMID: 30111755
Medicines (Basel). 2018 Aug 15;5(3). doi: 10.3390/medicines5030091.

Recent findings highlight the emerging role of the endocannabinoid system in the control of symptoms and disease progression in multiple sclerosis (MS). MS is a chronic, immune-mediated, demyelinating disorder of the central nervous system with no cure so far....

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Gado F, Digiacomo M, Macchia M, et al. Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis. Medicines (Basel). 2018;5(3)doi: 10.3390/medicines5030091.
Gado, F., Digiacomo, M., Macchia, M., Bertini, S., & Manera, C. (2018). Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis. Medicines (Basel, Switzerland), 5(3), . https://doi.org/10.3390/medicines5030091
Gado, Francesca, et al. "Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis." Medicines (Basel, Switzerland) vol. 5,3 (2018). doi: https://doi.org/10.3390/medicines5030091
Gado F, Digiacomo M, Macchia M, Bertini S, Manera C. Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis. Medicines (Basel). 2018 Aug 15;5(3). doi: 10.3390/medicines5030091. PMID: 30111755; PMCID: PMC6164967.
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Novel Synthetic Opioids: The Pathologist's Point of View.

Brain sciences

Frisoni P, Bacchio E, Bilel S, Talarico A, Gaudio RM, Barbieri M, Neri M, Marti M.
PMID: 30200549
Brain Sci. 2018 Sep 02;8(9). doi: 10.3390/brainsci8090170.

BACKGROUND: New Psychoactive Substances (NPS) constitute a broad range of hundreds of natural and synthetic drugs, including synthetic opioids, synthetic cannabinoids, synthetic cathinones, and other NPS classes, which were not controlled from 1961 to 1971 by the United Nations...

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Frisoni P, Bacchio E, Bilel S, et al. Novel Synthetic Opioids: The Pathologist's Point of View. Brain Sci. 2018;8(9)doi: 10.3390/brainsci8090170.
Frisoni, P., Bacchio, E., Bilel, S., Talarico, A., Gaudio, R. M., Barbieri, M., Neri, M., & Marti, M. (2018). Novel Synthetic Opioids: The Pathologist's Point of View. Brain sciences, 8(9), . https://doi.org/10.3390/brainsci8090170
Frisoni, Paolo, et al. "Novel Synthetic Opioids: The Pathologist's Point of View." Brain sciences vol. 8,9 (2018). doi: https://doi.org/10.3390/brainsci8090170
Frisoni P, Bacchio E, Bilel S, Talarico A, Gaudio RM, Barbieri M, Neri M, Marti M. Novel Synthetic Opioids: The Pathologist's Point of View. Brain Sci. 2018 Sep 02;8(9). doi: 10.3390/brainsci8090170. PMID: 30200549; PMCID: PMC6162684.
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Evaluation of the Endo-Uro trainer for semi-rigid ureteroscopy training.

Therapeutic advances in urology

Palaneer S, Aydin A, Janabi HA, Al-Jabir A, Macchione N, Khan MS, Dasgupta P, Ahmed K.
PMID: 31579093
Ther Adv Urol. 2019 Sep 22;11:1756287219875584. doi: 10.1177/1756287219875584. eCollection 2019.

BACKGROUND: The aim of this study was to evaluate the validity of evidence of the Endo-Uro Trainer (SAMED, Dresden, Germany) for semi-rigid ureteroscopy.METHODS: Novice (RESULTS: The evaluation survey revealed a realism rating in all aspects, with a mean Likert...

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Palaneer S, Aydin A, Janabi HA, et al. Evaluation of the Endo-Uro trainer for semi-rigid ureteroscopy training. Ther Adv Urol. 2019;11:1756287219875584doi: 10.1177/1756287219875584.
Palaneer, S., Aydin, A., Janabi, H. A., Al-Jabir, A., Macchione, N., Khan, M. S., Dasgupta, P., & Ahmed, K. (2019). Evaluation of the Endo-Uro trainer for semi-rigid ureteroscopy training. Therapeutic advances in urology, 111756287219875584. https://doi.org/10.1177/1756287219875584
Palaneer, Sharanya, et al. "Evaluation of the Endo-Uro trainer for semi-rigid ureteroscopy training." Therapeutic advances in urology vol. 11 (2019): 1756287219875584. doi: https://doi.org/10.1177/1756287219875584
Palaneer S, Aydin A, Janabi HA, Al-Jabir A, Macchione N, Khan MS, Dasgupta P, Ahmed K. Evaluation of the Endo-Uro trainer for semi-rigid ureteroscopy training. Ther Adv Urol. 2019 Sep 22;11:1756287219875584. doi: 10.1177/1756287219875584. eCollection 2019. PMID: 31579093; PMCID: PMC6759697.
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IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils.

Oncoimmunology

Lucarini V, Ziccheddu G, Macchia I, La Sorsa V, Peschiaroli F, Buccione C, Sistigu A, Sanchez M, Andreone S, D'Urso MT, Spada M, Macchia D, Afferni C, Mattei F, Schiavoni G.
PMID: 28680750
Oncoimmunology. 2017 Apr 20;6(6):e1317420. doi: 10.1080/2162402X.2017.1317420. eCollection 2017.

The alarmin IL-33 is an IL-1 family member that stimulates pleiotropic immune reactions depending on the target tissue and microenvironmental factors. In this study, we have investigated the role of IL-33/ST2 axis in antitumor response to melanoma. Injection of...

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Lucarini V, Ziccheddu G, Macchia I, et al. IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils. Oncoimmunology. 2017;6(6):e1317420doi: 10.1080/2162402X.2017.1317420.
Lucarini, V., Ziccheddu, G., Macchia, I., La Sorsa, V., Peschiaroli, F., Buccione, C., Sistigu, A., Sanchez, M., Andreone, S., D'Urso, M. T., Spada, M., Macchia, D., Afferni, C., Mattei, F., & Schiavoni, G. (2017). IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils. Oncoimmunology, 6(6), e1317420. https://doi.org/10.1080/2162402X.2017.1317420
Lucarini, Valeria, et al. "IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils." Oncoimmunology vol. 6,6 (2017): e1317420. doi: https://doi.org/10.1080/2162402X.2017.1317420
Lucarini V, Ziccheddu G, Macchia I, La Sorsa V, Peschiaroli F, Buccione C, Sistigu A, Sanchez M, Andreone S, D'Urso MT, Spada M, Macchia D, Afferni C, Mattei F, Schiavoni G. IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils. Oncoimmunology. 2017 Apr 20;6(6):e1317420. doi: 10.1080/2162402X.2017.1317420. eCollection 2017. PMID: 28680750; PMCID: PMC5486175.
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Adjuvant radiotherapy with brachytherapy boost in soft tissue sarcomas.

Journal of contemporary brachytherapy

Cortesi A, Galuppi A, Frakulli R, Arcelli A, Romani F, Mattiucci GC, Bianchi G, Ferrari S, Ferraro A, Farioli A, Gambarotti M, Righi A, Macchia G, Deodato F, Cilla S, Buwenge M, Valentini V, Morganti AG, Donati D, Cammelli S.
PMID: 28725250
J Contemp Brachytherapy. 2017 Jun;9(3):256-262. doi: 10.5114/jcb.2017.68215. Epub 2017 Jun 05.

PURPOSE: The standard primary treatment for soft tissue sarcoma (STS) is a wide surgical resection, preceded or followed by radiotherapy. Purpose of this retrospective study was to assess the efficacy of perioperative brachytherapy (BRT) plus postoperative external beam radiation...

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Cortesi A, Galuppi A, Frakulli R, et al. Adjuvant radiotherapy with brachytherapy boost in soft tissue sarcomas. J Contemp Brachytherapy. 2017;9(3):256-262doi: 10.5114/jcb.2017.68215.
Cortesi, A., Galuppi, A., Frakulli, R., Arcelli, A., Romani, F., Mattiucci, G. C., Bianchi, G., Ferrari, S., Ferraro, A., Farioli, A., Gambarotti, M., Righi, A., Macchia, G., Deodato, F., Cilla, S., Buwenge, M., Valentini, V., Morganti, A. G., Donati, D., & Cammelli, S. (2017). Adjuvant radiotherapy with brachytherapy boost in soft tissue sarcomas. Journal of contemporary brachytherapy, 9(3), 256-262. https://doi.org/10.5114/jcb.2017.68215
Cortesi, Annalisa, et al. "Adjuvant radiotherapy with brachytherapy boost in soft tissue sarcomas." Journal of contemporary brachytherapy vol. 9,3 (2017): 256-262. doi: https://doi.org/10.5114/jcb.2017.68215
Cortesi A, Galuppi A, Frakulli R, Arcelli A, Romani F, Mattiucci GC, Bianchi G, Ferrari S, Ferraro A, Farioli A, Gambarotti M, Righi A, Macchia G, Deodato F, Cilla S, Buwenge M, Valentini V, Morganti AG, Donati D, Cammelli S. Adjuvant radiotherapy with brachytherapy boost in soft tissue sarcomas. J Contemp Brachytherapy. 2017 Jun;9(3):256-262. doi: 10.5114/jcb.2017.68215. Epub 2017 Jun 05. PMID: 28725250; PMCID: PMC5509983.
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Characterization of Covalently Bound Anti-Human Immunoglobulins on Self-Assembled Monolayer Modified Gold Electrodes.

Advanced biosystems

Holzer B, Manoli K, Ditaranto N, Macchia E, Tiwari A, Di Franco C, Scamarcio G, Palazzo G, Torsi L.
PMID: 32646170
Adv Biosyst. 2017 Nov;1(11):e1700055. doi: 10.1002/adbi.201700055. Epub 2017 Jun 05.

Bioconjugated gold surfaces constitute interesting platforms for biosensing applications. The immobilization of antibodies such as anti-immunoglobulin G and M (anti-IgG and anti-IgM) on gold electrodes via self-assembled monolayers (SAMs) is here studied as a model system for further immunoassays...

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Holzer B, Manoli K, Ditaranto N, et al. Characterization of Covalently Bound Anti-Human Immunoglobulins on Self-Assembled Monolayer Modified Gold Electrodes. Adv Biosyst. 2017;1(11):e1700055doi: 10.1002/adbi.201700055.
Holzer, B., Manoli, K., Ditaranto, N., Macchia, E., Tiwari, A., Di Franco, C., Scamarcio, G., Palazzo, G., & Torsi, L. (2017). Characterization of Covalently Bound Anti-Human Immunoglobulins on Self-Assembled Monolayer Modified Gold Electrodes. Advanced biosystems, 1(11), e1700055. https://doi.org/10.1002/adbi.201700055
Holzer, Brigitte, et al. "Characterization of Covalently Bound Anti-Human Immunoglobulins on Self-Assembled Monolayer Modified Gold Electrodes." Advanced biosystems vol. 1,11 (2017): e1700055. doi: https://doi.org/10.1002/adbi.201700055
Holzer B, Manoli K, Ditaranto N, Macchia E, Tiwari A, Di Franco C, Scamarcio G, Palazzo G, Torsi L. Characterization of Covalently Bound Anti-Human Immunoglobulins on Self-Assembled Monolayer Modified Gold Electrodes. Adv Biosyst. 2017 Nov;1(11):e1700055. doi: 10.1002/adbi.201700055. Epub 2017 Jun 05. PMID: 32646170.
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Efficacy and safety of honeybee and wasp tyrosine-adsorbed venom immunotherapy.

The World Allergy Organization journal

Severino M, Simioni L, Bonadonna P, Cantone R, Cortellini G, Crescioli S, D'Angelo A, La Rosa L, Macchia D, Martignago I, Massolo A, Reccardini F, Bagnasco D, Passalacqua G.
PMID: 31768218
World Allergy Organ J. 2019 Nov 19;12(12):100086. doi: 10.1016/j.waojou.2019.100086. eCollection 2019 Dec.

INTRODUCTION: It is acknowledged that any claim of efficacy of allergen immunotherapy must be done for each specific product, and this remains true also for venom immunotherapy (VIT). Thus, we evaluated the efficacy and safety of a specific tyrosine-adsorbed...

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Severino M, Simioni L, Bonadonna P, et al. Efficacy and safety of honeybee and wasp tyrosine-adsorbed venom immunotherapy. World Allergy Organ J. 2019;12(12):100086doi: 10.1016/j.waojou.2019.100086.
Severino, M., Simioni, L., Bonadonna, P., Cantone, R., Cortellini, G., Crescioli, S., D'Angelo, A., La Rosa, L., Macchia, D., Martignago, I., Massolo, A., Reccardini, F., Bagnasco, D., & Passalacqua, G. (2019). Efficacy and safety of honeybee and wasp tyrosine-adsorbed venom immunotherapy. The World Allergy Organization journal, 12(12), 100086. https://doi.org/10.1016/j.waojou.2019.100086
Severino, Maurizio, et al. "Efficacy and safety of honeybee and wasp tyrosine-adsorbed venom immunotherapy." The World Allergy Organization journal vol. 12,12 (2019): 100086. doi: https://doi.org/10.1016/j.waojou.2019.100086
Severino M, Simioni L, Bonadonna P, Cantone R, Cortellini G, Crescioli S, D'Angelo A, La Rosa L, Macchia D, Martignago I, Massolo A, Reccardini F, Bagnasco D, Passalacqua G. Efficacy and safety of honeybee and wasp tyrosine-adsorbed venom immunotherapy. World Allergy Organ J. 2019 Nov 19;12(12):100086. doi: 10.1016/j.waojou.2019.100086. eCollection 2019 Dec. PMID: 31768218; PMCID: PMC6872772.
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Longitudinal study on the elderly population of a little town near Turin: preliminary results.

Archives of gerontology and geriatrics

Macchione C, Tamietti E, Santoro M, Gobbi C, Bianchi M, Giacometto F, Baietto T, Fantó F.
PMID: 18653088
Arch Gerontol Geriatr. 1996;22:523-6. doi: 10.1016/0167-4943(96)86993-7.

UNLABELLED: A longitudinal study on the over 65-year-old population (656 subjects) of a little town in the district of Turin (Italy) has started. A random sample of 200 people, stratified for sex and age, has been extracted and subdivided...

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Macchione C, Tamietti E, Santoro M, et al. Longitudinal study on the elderly population of a little town near Turin: preliminary results. Arch Gerontol Geriatr. 1996;22:523-6doi: 10.1016/0167-4943(96)86993-7.
Macchione, C., Tamietti, E., Santoro, M., Gobbi, C., Bianchi, M., Giacometto, F., Baietto, T., & Fantó, F. (1996). Longitudinal study on the elderly population of a little town near Turin: preliminary results. Archives of gerontology and geriatrics, 22523-6. https://doi.org/10.1016/0167-4943(96)86993-7
Macchione, C, et al. "Longitudinal study on the elderly population of a little town near Turin: preliminary results." Archives of gerontology and geriatrics vol. 22 (1996): 523-6. doi: https://doi.org/10.1016/0167-4943(96)86993-7
Macchione C, Tamietti E, Santoro M, Gobbi C, Bianchi M, Giacometto F, Baietto T, Fantó F. Longitudinal study on the elderly population of a little town near Turin: preliminary results. Arch Gerontol Geriatr. 1996;22:523-6. doi: 10.1016/0167-4943(96)86993-7. PMID: 18653088.
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Natural based products for cleaning copper and copper alloys artefacts.

Natural product research

Macchia A, Colasanti IA, Rivaroli L, Favero G, de Caro T, Pantoja Munoz L, Campanella L, La Russa MF.
PMID: 34753376
Nat Prod Res. 2021 Nov 09;1-8. doi: 10.1080/14786419.2021.2000408. Epub 2021 Nov 09.

Copper alloys objects can deteriorate their conservation state through irreversible corrosion. Since in the cultural heritage field every artefact is unique and any loss irreplaceable, solutions for conservation are needed. Hence, there is the necessity to stop the corrosion...

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Macchia A, Colasanti IA, Rivaroli L, et al. Natural based products for cleaning copper and copper alloys artefacts. Nat Prod Res. 2021;1-8doi: 10.1080/14786419.2021.2000408.
Macchia, A., Colasanti, I. A., Rivaroli, L., Favero, G., de Caro, T., Pantoja Munoz, L., Campanella, L., & La Russa, M. F. (2021). Natural based products for cleaning copper and copper alloys artefacts. Natural product research, 1-8. https://doi.org/10.1080/14786419.2021.2000408
Macchia, Andrea, et al. "Natural based products for cleaning copper and copper alloys artefacts." Natural product research vol. (2021): 1-8. doi: https://doi.org/10.1080/14786419.2021.2000408
Macchia A, Colasanti IA, Rivaroli L, Favero G, de Caro T, Pantoja Munoz L, Campanella L, La Russa MF. Natural based products for cleaning copper and copper alloys artefacts. Nat Prod Res. 2021 Nov 09;1-8. doi: 10.1080/14786419.2021.2000408. Epub 2021 Nov 09. PMID: 34753376.
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Unravelling similarities and differences in the role of circular and linear PVT1 in cancer and human disease.

British journal of cancer

Traversa D, Simonetti G, Tolomeo D, Visci G, Macchia G, Ghetti M, Martinelli G, Kristensen LS, Storlazzi CT.
PMID: 34754096
Br J Cancer. 2021 Nov 09; doi: 10.1038/s41416-021-01584-7. Epub 2021 Nov 09.

The plasmacytoma variant translocation 1 (PVT1) is a long non-coding RNA gene involved in human disease, mainly in cancer onset/progression. Although widely analysed, its biological roles need to be further clarified. Notably, functional studies on PVT1 are complicated by...

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Traversa D, Simonetti G, Tolomeo D, et al. Unravelling similarities and differences in the role of circular and linear PVT1 in cancer and human disease. Br J Cancer. 2021;doi: 10.1038/s41416-021-01584-7.
Traversa, D., Simonetti, G., Tolomeo, D., Visci, G., Macchia, G., Ghetti, M., Martinelli, G., Kristensen, L. S., & Storlazzi, C. T. (2021). Unravelling similarities and differences in the role of circular and linear PVT1 in cancer and human disease. British journal of cancer, . https://doi.org/10.1038/s41416-021-01584-7
Traversa, Debora, et al. "Unravelling similarities and differences in the role of circular and linear PVT1 in cancer and human disease." British journal of cancer vol. (2021). doi: https://doi.org/10.1038/s41416-021-01584-7
Traversa D, Simonetti G, Tolomeo D, Visci G, Macchia G, Ghetti M, Martinelli G, Kristensen LS, Storlazzi CT. Unravelling similarities and differences in the role of circular and linear PVT1 in cancer and human disease. Br J Cancer. 2021 Nov 09; doi: 10.1038/s41416-021-01584-7. Epub 2021 Nov 09. PMID: 34754096.
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Effects of intrauterine exposure to concentrated ambient particles on allergic sensitization in juvenile mice.

Toxicology

de Brito JM, de Ameida FM, Arantes-Costa FM, Guimarães ET, Morgan A, Mangone FR, Pavanelli AC, Nagai MA, Vieira RP, Macchione M, Mauad T.
PMID: 34606951
Toxicology. 2021 Nov;463:152970. doi: 10.1016/j.tox.2021.152970. Epub 2021 Oct 01.

Intrauterine exposure to particulate matter (PM) has been associated with an increased risk of asthma development, which may differ by the age of asthma onset, sex, and pollutant concentration. To investigate the pulmonary effects of in utero exposure to...

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de Brito JM, de Ameida FM, Arantes-Costa FM, et al. Effects of intrauterine exposure to concentrated ambient particles on allergic sensitization in juvenile mice. Toxicology. 2021;463:152970doi: 10.1016/j.tox.2021.152970.
de Brito, J. M., de Ameida, F. M., Arantes-Costa, F. M., Guimarães, E. T., Morgan, A., Mangone, F. R., Pavanelli, A. C., Nagai, M. A., Vieira, R. P., Macchione, M., & Mauad, T. (2021). Effects of intrauterine exposure to concentrated ambient particles on allergic sensitization in juvenile mice. Toxicology, 463152970. https://doi.org/10.1016/j.tox.2021.152970
de Brito, Jôse Mára, et al. "Effects of intrauterine exposure to concentrated ambient particles on allergic sensitization in juvenile mice." Toxicology vol. 463 (2021): 152970. doi: https://doi.org/10.1016/j.tox.2021.152970
de Brito JM, de Ameida FM, Arantes-Costa FM, Guimarães ET, Morgan A, Mangone FR, Pavanelli AC, Nagai MA, Vieira RP, Macchione M, Mauad T. Effects of intrauterine exposure to concentrated ambient particles on allergic sensitization in juvenile mice. Toxicology. 2021 Nov;463:152970. doi: 10.1016/j.tox.2021.152970. Epub 2021 Oct 01. PMID: 34606951.
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Sustained symptomatic remission in schizophrenia: Course and predictors from a two-year prospective study.

Schizophrenia research

Carpiniello B, Pinna F, Manchia M, Tusconi M, Cavallaro R, Bosia M.
PMID: 34839071
Schizophr Res. 2021 Nov 25;239:34-41. doi: 10.1016/j.schres.2021.11.023. Epub 2021 Nov 25.

BACKGROUND: Although remission is a priority target in psychosis, reported rates show a marked variation across studies and instability over time. Such variability, partly due to methodology, emphasizes the need to define the optimal assessment procedure, as well as...

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Carpiniello B, Pinna F, Manchia M, et al. Sustained symptomatic remission in schizophrenia: Course and predictors from a two-year prospective study. Schizophr Res. 2021;239:34-41doi: 10.1016/j.schres.2021.11.023.
Carpiniello, B., Pinna, F., Manchia, M., Tusconi, M., Cavallaro, R., & Bosia, M. (2021). Sustained symptomatic remission in schizophrenia: Course and predictors from a two-year prospective study. Schizophrenia research, 23934-41. https://doi.org/10.1016/j.schres.2021.11.023
Carpiniello, Bernardo, et al. "Sustained symptomatic remission in schizophrenia: Course and predictors from a two-year prospective study." Schizophrenia research vol. 239 (2021): 34-41. doi: https://doi.org/10.1016/j.schres.2021.11.023
Carpiniello B, Pinna F, Manchia M, Tusconi M, Cavallaro R, Bosia M. Sustained symptomatic remission in schizophrenia: Course and predictors from a two-year prospective study. Schizophr Res. 2021 Nov 25;239:34-41. doi: 10.1016/j.schres.2021.11.023. Epub 2021 Nov 25. PMID: 34839071.
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