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Showing 601 to 612 of 612 entries
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Proteomic Dissection of the Impact of Environmental Exposures on Mouse Seminal Vesicle Function.

Molecular & cellular proteomics : MCP

Skerrett-Byrne DA, Trigg NA, Bromfield EG, Dun MD, Bernstein IR, Anderson AL, Stanger SJ, MacDougall LA, Lord T, Aitken RJ, Roman SD, Robertson SA, Nixon B, Schjenken JE.
PMID: 34089863
Mol Cell Proteomics. 2021;20:100107. doi: 10.1016/j.mcpro.2021.100107. Epub 2021 Jun 02.

Seminal vesicles are an integral part of the male reproductive accessory gland system. They produce a complex array of secretions containing bioactive constituents that support gamete function and promote reproductive success, with emerging evidence suggesting these secretions are influenced...

Strategies for extended lifetime of implantable intraperitoneal insulin catheters.

Journal of controlled release : official journal of the Controlled Release Society

He J, Renard E, Lord P, Cohen D, Gu B, Wang X, Yenduri G, Burgess DJ.
PMID: 34856228
J Control Release. 2021 Nov 29;341:487-497. doi: 10.1016/j.jconrel.2021.11.038. Epub 2021 Nov 29.

Implantable insulin infusion systems using the intra-peritoneal route have dramatically changed the management of diabetes paving the way toward the realization of the potential "holy grail" of a fully implantable artificial pancreas. However, the wear duration of delivery catheters...

The evolutionary trade-offs in phage-resistant Klebsiella pneumoniae entail cross-phage sensitization and loss of multidrug resistance.

Environmental microbiology

Majkowska-Skrobek G, Markwitz P, Sosnowska E, Lood C, Lavigne R, Drulis-Kawa Z.
PMID: 33754440
Environ Microbiol. 2021 Mar 22; doi: 10.1111/1462-2920.15476. Epub 2021 Mar 22.

Bacteriophage therapy is currently being evaluated as a critical complement to traditional antibiotic treatment. However, the emergence of phage resistance is perceived as a major hurdle to the sustainable implementation of this antimicrobial strategy. By combining comprehensive genomics and...

Non-cardiogenic pulmonary oedema complicating balloon valvuloplasty and stent angioplasty of severe pulmonary valve stenosis in four dogs.

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology

Santarelli G, Bouvard J, Brethel SF, Gordon S, Lord S, Mavropoulou A, Oliveira P, Sykes KT, Swift S, Culshaw GJ.
PMID: 34999479
J Vet Cardiol. 2021 Dec 08;39:79-88. doi: 10.1016/j.jvc.2021.12.003. Epub 2021 Dec 08.

In dogs, balloon valvuloplasty is considered the treatment of choice for severe pulmonary valve stenosis, and this technique is currently performed routinely in specialist referral practices with low morbidity and mortality. Stent angioplasty has also been recently proposed as...

Robust humoral and cellular immune responses and low risk for reinfection at least 8 months following asymptomatic to mild COVID-19.

Journal of internal medicine

Havervall S, Ng H, Jernbom Falk A, Greilert-Norin N, Månberg A, Marking U, Laurén I, Gabrielsson L, Salomonsson AC, Aguilera K, Kihlgren M, Månsson M, Rosell A, Hellström C, Andersson E, Olofsson J, Skoglund L, Yousef J, Pin E, Lord M, Åberg M, Hedhammar M, Tegel H, Dönnes P, Phillipson M, Nilsson P, Klingström J, Mangsbo S, Hober S, Thålin C.
PMID: 34459525
J Intern Med. 2022 Jan;291(1):72-80. doi: 10.1111/joim.13387. Epub 2021 Sep 27.

BACKGROUND: Emerging data support detectable immune responses for months after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and vaccination, but it is not yet established to what degree and for how long protection against reinfection lasts.METHODS: We investigated...

PARP Inhibitors - Trapped in a Toxic Love Affair.

Cancer research

Krastev DB, Wicks AJ, Lord CJ.
PMID: 34782321
Cancer Res. 2021 Nov 15;81(22):5605-5607. doi: 10.1158/0008-5472.CAN-21-3201.

It is often the case that when an investigational cancer drug first enters clinical development, its precise mechanism of action is unclear. This was the case for PARP inhibitors (PARPi) used to treat homologous recombination-defective cancers. In 2012, nearly...

The COVID-19 pandemic and eating disorders in children, adolescents, and emerging adults: virtual care recommendations from the Canadian consensus panel during COVID-19 and beyond.

Journal of eating disorders

Couturier J, Pellegrini D, Miller C, Bhatnagar N, Boachie A, Bourret K, Brouwers M, Coelho JS, Dimitropoulos G, Findlay S, Ford C, Geller J, Grewal S, Gusella J, Isserlin L, Jericho M, Johnson N, Katzman DK, Kimber M, Lafrance A, Leclerc A, Loewen R, Loewen T, McVey G, Norris M, Pilon D, Preskow W, Spettigue W, Steinegger C, Waite E, Webb C.
PMID: 33863388
J Eat Disord. 2021 Apr 16;9(1):46. doi: 10.1186/s40337-021-00394-9.

OBJECTIVE: The COVID-19 pandemic has had detrimental effects on mental health. Literature on the impact on individuals with eating disorders is slowly emerging. While outpatient eating disorder services in Canada have attempted to transition to virtual care, guidelines related...

Serum Cardiac and Skeletal Muscle Marker Changes in Repetitive Breath-hold Diving.

Sports medicine - open

Cialoni D, Brizzolari A, Sponsiello N, Lancellotti V, Lori C, Bosco G, Marroni A, Barassi A.
PMID: 34417928
Sports Med Open. 2021 Aug 21;7(1):58. doi: 10.1186/s40798-021-00349-z.

BACKGROUND: Breath-hold diving (BH-diving) is associated to extreme environmental conditions, prolonged physical activity, and complex adaptation mechanisms to supply enough ORESULTS: We found statistically significant increases of CK (T0: 136.1% p < 0.0001; T1: 138.5%, p < 0.0001), CK-MBm...

Care Provider Behaviors That Shape Parent Identity as a "Good Parent" to Their Seriously Ill Child.

Palliative medicine reports

Neumann ML, Weaver MS, Lord B, Wiener L, Hinds PS.
PMID: 33937910
Palliat Med Rep. 2021 Apr 27;2(1):113-121. doi: 10.1089/pmr.2021.0005. eCollection 2021.

No abstract available.

Point-of-Care Ultrasound Assisting in the Rapid Diagnosis of Acute Cholangitis 60 Years After Cholecystectomy.

The Journal of emergency medicine

Georges N, Ford C, Moreno M, Zagroba S.
PMID: 34511296
J Emerg Med. 2021 Sep 09; doi: 10.1016/j.jemermed.2021.07.001. Epub 2021 Sep 09.

BACKGROUND: Point-of-care ultrasound (POCUS) is used frequently to evaluate the right upper quadrant of patients with high suspicion for biliary pathology. In patients with a history of cholecystectomy, the utility of POCUS can be overlooked.CASE REPORT: We report the...

Social Determinants of Health Attenuate the Relationship Between Race and Ethnicity and White Matter Hyperintensity Severity but not Microbleed Presence in Patients with Intracerebral Hemorrhage.

Neurocritical care

Bauman KM, Yaghi S, Lewis A, Agarwal S, Changa A, Dogra S, Litao M, Sanger M, Lord A, Ishida K, Zhang C, Czeisler B, Torres J, Dehkharghani S, Frontera JA, Melmed KR.
PMID: 34918215
Neurocrit Care. 2021 Dec 16; doi: 10.1007/s12028-021-01403-0. Epub 2021 Dec 16.

BACKGROUND: The association between race and ethnicity and microvascular disease in patients with intracerebral hemorrhage (ICH) is unclear. We hypothesized that social determinants of health (SDOHs) mediate the relationship between race and ethnicity and severity of white matter hyperintensities...

Work and well-being: Vocational activity trajectories in young adults with autism spectrum disorder.

Autism research : official journal of the International Society for Autism Research

Clarke EB, Sterrett K, Lord C.
PMID: 34516710
Autism Res. 2021 Dec;14(12):2613-2624. doi: 10.1002/aur.2606. Epub 2021 Sep 13.

Young adults with autism spectrum disorder (ASD) experience limited social connectedness, difficulty living independently, and other poor outcomes at high rates. Vocational activities, including employment and postsecondary education, are associated with increased positive outcomes and subjective well-being in typical...

Showing 601 to 612 of 612 entries